Journal of the Japan Society of the Reticuloendothelial System最新文献_第3页

Immunological responses in the aged with bacterial infection. 老年细菌感染的免疫应答。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.36.251

M. Fukayama, M. Kawakami, M. Mori, M. Utsuyama

引用次数: 0

Histopathologic study of the liver after allogeneic bone marrow transplantation: Significance of hepatic graft-versus-host disease. 同种异体骨髓移植后肝脏的组织病理学研究:肝脏移植物抗宿主病的意义。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.29.21

N. Hirabayashi, Masafumi Ito

{"title":"Histopathologic study of the liver after allogeneic bone marrow transplantation: Significance of hepatic graft-versus-host disease.","authors":"N. Hirabayashi, Masafumi Ito","doi":"10.3960/JSLRT1961.29.21","DOIUrl":"https://doi.org/10.3960/JSLRT1961.29.21","url":null,"abstract":"Postmortem livers from 38 cases were histologically examined to assess relative importance of hepatic graft-versus-host disease (GVHD) for liver dysfunction after allogeneic bone marrow transplantation. Hepatic GVHD, based on the finding of bile duct atypia, was present in 24 of 25 cases with clinical signs of GVHD (acute 14, chronic 11), and in none of 13 cases without clinical GVHD. Of the 25 cases with clinical GVHD17 (68%) had veno-occlusive disease (VOD), and 12 (48%) had opportunistic viral infections (cytomegalovirus 7, varicella-zoster virus 3, adenovirus 1, herpes simplex virus 1). Hepatic peliosis was present in two cases given azathioprine to suppress chronic GVHD. Azathioprine was also causal factor for the late occurrence of VOD in three cases. Extensive hepatocellular necrosis in the centrilobular region was found in a case treated with cyclosporin-A (CsA). All of the seven cases with hepatic failure had serious complications including VOD, peliosis, CsA hepatotoxicity and viral hepatitis either alone or in combination. In contrast, these hepatic comlications could not be found in five cases whithout cholestasis in the liver. Our results suggest that factors other than GVHD are responsible for severe cholestatic dysfunction of the liver.","PeriodicalId":237003,"journal":{"name":"Journal of the Japan Society of the Reticuloendothelial System","volume":"383 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124766660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Present states and molecular pathological analysis for Hodgkins' disease research. 何杰金氏病研究现状及分子病理分析。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.33.297

A. Mikata

引用次数: 0

Gelatinous transformation of the bone marrow in anorexia nervosa: Report of two cases. 神经性厌食症骨髓胶质转化:附2例报告。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.30.193

H. Taguchi, H. Enzan, K. Shibuya, Hirotoshi Sato, H. Ikeda, H. Hara, I. Miyoshi

引用次数: 3

High dose chemotherapy followed by autologous bone marrow transplantation (ABMT) and daily infusion of granulocyte colony stimulating factor (G-CSF) for malignant tumors in adults. 成人恶性肿瘤大剂量化疗后自体骨髓移植(ABMT)及每日输注粒细胞集落刺激因子(G-CSF)。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/jslrt1961.31.479

K. Tobinai, K. Takeyama, A. Kohno, M. Hayashi, M. Narabayashi, K. Tamayose, M. Shimoyama

{"title":"High dose chemotherapy followed by autologous bone marrow transplantation (ABMT) and daily infusion of granulocyte colony stimulating factor (G-CSF) for malignant tumors in adults.","authors":"K. Tobinai, K. Takeyama, A. Kohno, M. Hayashi, M. Narabayashi, K. Tamayose, M. Shimoyama","doi":"10.3960/jslrt1961.31.479","DOIUrl":"https://doi.org/10.3960/jslrt1961.31.479","url":null,"abstract":"Fourteen adult patients with resistant malignant tumors (3 with malignant lymphoma, 3 with acute lymphocytic leukemia, 5 with recurrent breast cancer and 3 with germ cell tumor) received high dose chemotherapy followed by autologous bone marrow transplantation (ABMT) and daily infusion of granulocyte colony stimulating factor (G-CSF). All the 14 patients showed bone marrow engraftment. Median neutrophilic recovery over 500/cmm was 12 days after ABMT, and no life-threatening infection occurred during neutropenic period. As compared with literature controls of high dose chemotherapy followed by ABMT not using G-CSF in Western countries, our results showed earlier recovery of neutrophils. It is suggested that G-CSF may shorten neutropenic period after ABMT. Non-hematologic regimen-related toxicities were under control. No therapy-related death was observed. Disease oriented, multicenter phase II studies of high dose chemotherapy followed by ABMT and daily infusion of G-CSF are ongoing.","PeriodicalId":237003,"journal":{"name":"Journal of the Japan Society of the Reticuloendothelial System","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129047051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scanning electron microscopic observation of the splenic sinus in idiopathic portal hypertension. 特发性门静脉高压脾窦的扫描电镜观察。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.31.257

Takehiko Sato

引用次数: 1

Immunopathological study of graft versus host disease (GVHD). 移植物抗宿主病(GVHD)免疫病理研究。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.29.33

S. Mori, H. Kodo

引用次数: 0

Immunopathophysiological study of amyloidosis induced by tumor transplantation and its modification. 肿瘤移植诱导淀粉样变性的免疫病理生理研究及其修饰。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.23.107

T. Nakano

引用次数: 0

T cell repertoire involved in GBHR. 参与GBHR的T细胞库。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.35.281

K. Onoé

引用次数: 0

T cells and its aging. T细胞及其老化。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.36.227

M. Utsuyama, C. Kurashima, K. Hirokawa

{"title":"T cells and its aging.","authors":"M. Utsuyama, C. Kurashima, K. Hirokawa","doi":"10.3960/JSLRT1961.36.227","DOIUrl":"https://doi.org/10.3960/JSLRT1961.36.227","url":null,"abstract":"The function of immune system peaks at around puberty and gradually declines thereafter with advance in age. The age-related decline of immunological function primarily occurs in T cell-dependent immune system and is generally associated with increase in susceptibility to infections as well as in incidence of autoimmune phenomena in the elderly. The age-related change in T cell-dependent immune functions can be ascribed to the physiological thymic atrophy which starts in an early stage of life. Emigration of T cells from the thymus to the periphery mainly takes place in the late fetal and newborn stage, and dramatically declines after puberty. In other word, the thymic capacity to promote T cell differentiation starts to change in the early stage of life in terms of quantity and quality of T cells. Age-related quantitative changes of aging T cells are seen in their number and subsets. Thus, the composition of T cell-subsets in the periphery gradually changes with age, resulting in the alteration of T cell functions in the elderly. In relation to the qualitative change of aging T cells, disturbance of intracellular signal transduction is responsible for the impairment of proliferation and cytokine production upon antigenic stimulation. However, age-related change of immune functions are controlled not only by T cells but also by endogenous and exogenous factors. In other words, the age-related alteration of immune functions in T cells might be further explained by proper understanding of the relationship between the neuroendocrine and the immune system.","PeriodicalId":237003,"journal":{"name":"Journal of the Japan Society of the Reticuloendothelial System","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131710042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0