Veterinary anaesthesia and analgesia最新文献

{"title":"Reproducibility and diagnostic accuracy of the Unesp-Botucatu Feline Pain Scale and the visual analogue scale among laypeople, cat owners, students and experienced veterinarians","authors":"Mirella M. Neves ,&nbsp;Mayara T. de Lima ,&nbsp;Pedro H.E. Trindade ,&nbsp;Marcela C. Oliveira ,&nbsp;Beatriz P. Monteiro ,&nbsp;Nadia Crosignani ,&nbsp;Chia T. Tseng ,&nbsp;Kazuto Yamashita ,&nbsp;Peter W. Kronen ,&nbsp;Stelio P.L. Luna","doi":"10.1016/j.vaa.2025.10.001","DOIUrl":"10.1016/j.vaa.2025.10.001","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the reproducibility and diagnostic accuracy of the Unesp-Botucatu Feline Pain Scale short form (UFEPS-SF) and the Visual Analogue Scale (VAS) among untrained laypersons, cat owners, veterinary students and experienced veterinarians.</div></div><div><h3>Study design</h3><div>Blind and randomized.</div></div><div><h3>Animals</h3><div>Videos of 10 female cats.</div></div><div><h3>Methods</h3><div>Three self-declared female and three male raters were included per group of experienced veterinarians, students, cat owners and laypersons (<em>n</em> = 24). Participants assessed 40 videos of female cats that underwent ovariohysterectomy: preoperative, postoperative, post-rescue analgesia, and 24 hours postoperatively. A multilevel generalized linear model followed by Bonferroni <em>post hoc</em> test was used to evaluate differences in UFEPS-SF scores between groups. Interobserver agreement was calculated by intraclass correlation coefficient (ICC) between pairs of observers within each group. Area under the curve (AUC) for the receiver operating characteristic curves, specificity (no pain) and sensitivity (pain) were calculated.</div></div><div><h3>Results</h3><div>ICC for UFEPS-SF was higher for veterinarians and students than for laypersons and cat owners, although all results were very good (≥0.81). Reliability of the VAS was very good for experienced observers only. Females assigned higher median scores than males only at 24 hours postoperatively. UFEPS-SF specificity [confidence interval (CI)] and sensitivity (CI) were 0.83–1 (0.7–1) and 0.98–1 (0.91–1), respectively, and diagnostic accuracy [AUC (CI)] was excellent across all groups [0.99–1 (0.97–1)], with no significant differences between groups. The predictive capacity (AUC) of the VAS followed the order: experienced &gt; students &gt; cat owners = laypersons. VAS AUC values were lower than those of UFEPS-SF.</div></div><div><h3>Conclusions and clinical relevance</h3><div>The UFEPS-SF can be reliably used by untrained laypersons, cat owners and students with no experience to identify acute postoperative pain in cats. The reproducibility, sensitivity and diagnostic accuracy of the VAS were suboptimal and inferior to those of the UFEPS-SF, except among experienced observers.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101145"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145446065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gas leakage around cuffed endotracheal tubes and the effect of gel lubrication: in vitro and ex vivo models","authors":"Hamaseh Tayari ,&nbsp;Ricardo Felisberto ,&nbsp;Jenny Shortland ,&nbsp;Angela Briganti ,&nbsp;Alex Dugdale","doi":"10.1016/j.vaa.2025.11.008","DOIUrl":"10.1016/j.vaa.2025.11.008","url":null,"abstract":"<div><h3>Objective</h3><div>To determine whether inflating high-volume, low-pressure (HVLP) endotracheal tube (ETT) cuffs to 30 cmH₂O prevents significant gas leakage (&gt;5 mL) during intermittent positive-pressure ventilation (IPPV) in rigid <em>in vitro</em> and <em>ex vivo</em> porcine tracheal models, and whether ETT cuff lubrication reduces the pressure needed for an effective airway seal.</div></div><div><h3>Study design</h3><div>Prospective, randomised, crossover design.</div></div><div><h3>Animals</h3><div>A group of 20 porcine excised tracheae.</div></div><div><h3>Methods</h3><div>Phase 1: In a rigid <em>in vitro</em> tracheal model (PVC tube, 22 mm inner diameter, 30 ° incline) connected to a 1 L test lung delivering IPPV (peak inspiratory pressure 10 cmH₂O, 12 breaths minute^-1, inspiratory:expiratory ratio 1:3), randomly selected HVLP ETTs (five per size, 7.0–10.0 mm inner diameter) were inserted and cuffs inflated to 30 cmH₂O. Gas leakage during IPPV, determined as inspiratory–expiratory volume difference (ΔI–E), was measured 12 times per ETT, before and after water-soluble gel lubrication. Phase 2 replicated the experiments using 20 <em>ex vivo</em> porcine tracheae [20 mm ± 2 mm inner diameter (mean ± standard deviation)]. Finally, minimum cuff pressures required to achieve negligible leakage (≤5 mL) were determined before and after lubrication. Statistical analyses included t-tests, Wilcoxon signed-rank, and Kruskal–Wallis tests, with Conover–Iman <em>post hoc</em> and Bonferroni corrections.</div></div><div><h3>Results</h3><div><em>In vitro</em>, median ΔI–E before lubrication was 155 mL (7.0 mm), 77 mL (8.0 mm), 27 mL (9.0 mm), and 20 mL (10.0 mm). Lubrication reduced leakage (<em>p</em> &lt; 0.0001) and cuff pressures by 8.7 ± 10.4 to 22 ± 4.2 cmH₂O. <em>Ex vivo</em>, median ΔI–E before lubrication was 22 mL (7.0 mm), 20 mL (8.0 mm), 19 mL (9.0 mm), and 12 mL (10.0 mm). Lubrication reduced leakage (<em>p</em> &lt; 0.0001) and cuff pressures by 3.4 ± 1.5 to 12 ± 9.5 cmH₂O. Leakage differed significantly between sizes before and after lubrication (<em>p</em> &lt; 0.0001).</div></div><div><h3>Conclusions</h3><div>Inflating HVLP ETT cuffs to 30 cmH₂O alone did not reliably prevent gas leakage, but lubrication significantly reduced leakage and the cuff pressure required for an effective airway seal, particularly in smaller ETTs.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101164"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145842242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of cardiac output and Hypotension Prediction Index using HemoSphere Acumen IQ Monitoring System in sevoflurane-anesthetized dogs","authors":"Vaidehi V. Paranjape ,&nbsp;Tayla Regenbaum ,&nbsp;Syon Link ,&nbsp;Aliya Magee ,&nbsp;Chin-Chi Liu ,&nbsp;Jeannette Cremer","doi":"10.1016/j.vaa.2025.10.012","DOIUrl":"10.1016/j.vaa.2025.10.012","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate agreement between cardiac output (CO) from intermittent pulmonary artery thermodilution (iPATD-CO) and HemoSphere with Acumen IQ sensor (HSIQ-CO) in sevoflurane-anesthetized, normovolemic and hypovolemic dogs. Also, to analyze HSIQ-derived Hypotension Prediction Index (HPI) trends, and investigate its relationship with invasive mean arterial blood pressure (MAP).</div></div><div><h3>Study design</h3><div>Blinded, nonrandomized, experimental observational study.</div></div><div><h3>Animals</h3><div>Eight mixed-breed female intact dogs.</div></div><div><h3>Methods</h3><div>Dogs were anesthetized on two occasions. In both anesthetic events, iPATD-CO and HSIQ-CO (via dorsal metatarsal artery) were measured 10 times every 10 minutes during normovolemia and 10 times every 10 minutes starting 20 minutes after a 15% blood loss (hypovolemia). Agreement between iPATD-CO and HSIQ-CO was assessed with Bland–Altman, four-quadrant and polar plot analyses. To evaluate MAP–HPI relationship, 100 standardized time points per dog per anesthetic event were uniformly sampled across the anesthetic period from instrumentation to recovery. Area under the receiver operating characteristic (AUROC) curve was used to compare HPI with short-term MAP changes (1–5 minutes) for predicting hypotension (MAP ≤ 65 mmHg &gt; 1 minute) at 5, 10 and 15 minutes. Youden’s index provided optimal HPI thresholds for predicting hypotension.</div></div><div><h3>Results</h3><div>HSIQ-CO showed significant overestimation which increased further with hypovolemia. HSIQ-CO measurements had a high percentage error (73%), and poor trending compared with iPATD-CO. HPI strongly predicted hypotension (AUROC &gt; 0.90), outperforming short-term MAP fluctuations (AUROC ≈ 0.50). Optimal HPI thresholds of 97–98 accurately predicted hypotension 15 minutes before onset.</div></div><div><h3>Conclusions and clinical relevance</h3><div>HSIQ proved unreliable for CO measurement; however, HPI accurately predicted hypotension up to 15 minutes, highlighting its potential clinical utility in veterinary anesthesia.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101156"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145640567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of sugammadex to reverse alfaxalone anesthesia in rats","authors":"Benjamin Chen ,&nbsp;Robert J. Brosnan ,&nbsp;Antonio JA. Aguiar","doi":"10.1016/j.vaa.2025.11.004","DOIUrl":"10.1016/j.vaa.2025.11.004","url":null,"abstract":"<div><h3>Objective</h3><div>To test whether sugammadex, a reversal agent for steroid neuromuscular blocking drugs, could encapsulate the neurosteroid alfaxalone and accelerate anesthetic recovery.</div></div><div><h3>Study design</h3><div>Prospective, blinded, randomized, crossover study.</div></div><div><h3>Animals</h3><div>Thirty-six male and female adult Sprague-Dawley rats.</div></div><div><h3>Methods</h3><div>Six male and six female adult Sprague-Dawley rats were intravenously administered 3 mg kg⁻¹ alfaxalone followed 1 minute later by either 0.9% saline or 96 mg kg⁻¹ sugammadex, with a 1 week washout period between repeat anesthetics. A separate cohort of 12 rats was studied using an identical experimental design, but with a 6 mg kg⁻¹ alfaxalone dose. A third cohort of 12 rats was given 12 mg kg⁻¹ alfaxalone followed by saline or sugammadex (96 mg kg⁻¹ dose or 192 mg kg⁻¹ dose) using a Latin-square crossover design with 1 week between repeated anesthetics. Physiological and behavioral recovery responses were assessed every minute by an observer who was blinded to treatment. Data were analyzed using repeated-measures ANOVA with Šidák <em>post hoc</em> comparisons (<em>p</em> &lt; 0.05).</div></div><div><h3>Results</h3><div>Compared with saline controls, sugammadex shortened recovery times by 40–60% following anesthesia induction with the 3 or 6 mg kg⁻¹ alfaxalone doses (<em>p</em> ≤ 0.002). For the 12 mg kg⁻¹ alfaxalone dose, the low and the high sugammadex doses shortened recovery times by 25–50% and 50–61%, respectively, compared with saline controls, with all differences being significant (<em>p</em> ≤ 0.003) except for movement following tail clamp (<em>p</em> = 0.112–0.419). This higher sugammadex dose also shortened the same significant recovery end points compared with the lower sugammadex dose (<em>p</em> = 0.007–0.050). At higher alfaxalone doses, female rats exhibited significantly slower recoveries than male rats.</div></div><div><h3>Conclusions and clinical relevance</h3><div>Sugammadex can be used to reverse anesthetic effects from alfaxalone in rats. Recovery speed from alfaxalone anesthesia is dependent on sugammadex dose and sex.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101160"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145744923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a surgical drain for continuous postoperative trigeminal nerve block in a dog","authors":"Shengwei Qiao ,&nbsp;Verónica Re Bravo","doi":"10.1016/j.vaa.2025.10.011","DOIUrl":"10.1016/j.vaa.2025.10.011","url":null,"abstract":"<div><div>A male, neutered, mixed-breed dog, aged 12 years, was referred for a left mandibulectomy resulting from the recurrence of a squamous cell carcinoma in the vertical ramus of the left mandible. Preoperative pain management consisted of methadone 0.2 mg kg^–1 intravenously and an ultrasound-guided trigeminal nerve block with bupivacaine. Intraoperatively, a Jackson–Pratt drain connected to a continuous suction bulb was placed in the vicinity of the trigeminal nerve for postoperative bupivacaine delivery and exudate drainage. Bupivacaine 0.13% was delivered every 4 hours along with subcutaneous meloxicam (0.2 mg kg^–1, followed by 0.1 mg kg^–1 every 24 hours). No opioid rescue analgesia was needed postoperatively based on the short-form Glasgow Composite Measure Pain Scale. The dog began eating voluntarily 4 hours after surgery without signs of pain or discomfort. The drain was removed after 24 hours and the dog was discharged 24 hours postoperatively with oral meloxicam.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101155"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145597649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative acute kidney injury in dogs undergoing elective desexing surgery","authors":"Christopher T. Quinn,&nbsp;Randi Rotne,&nbsp;Emily Dockray,&nbsp;Andrew Neil Walton","doi":"10.1016/j.vaa.2025.10.005","DOIUrl":"10.1016/j.vaa.2025.10.005","url":null,"abstract":"<div><h3>Objective</h3><div>To report the incidence of acute kidney injury (AKI) in dogs after elective desexing surgery.</div></div><div><h3>Study design</h3><div>Prospective observational clinical study.</div></div><div><h3>Animals</h3><div>A group of 165 (71 male and 94 female) dogs admitted for castration or ovariohysterectomy.</div></div><div><h3>Methods</h3><div>Inclusion criteria were normal physical examination findings and no history of cardiovascular or renal disease. Serum creatinine (sCr) was measured before anaesthesia, and 24 and 48 hours postoperatively. AKI was defined by an increase (&gt; 26 μmol L^–1) in sCr from preoperative to 24 or 48 hours postoperatively. Changes in mean sCr pre-to post-anaesthesia were compared using paired <em>t</em>-tests. Differences in variables were compared between dogs with and without AKI with Fisher’s exact test for categorical data and continuous data using <em>t</em>-test or Mann–Whitney <em>U</em> test. Multivariable logistic regression was used to assess the significance of potential risk factors identified by univariable comparisons between AKI and non-AKI cases.</div></div><div><h3>Results</h3><div>Mean ± standard deviation age and body weight were 2.1 ± 1.7 years and 20.3 ± 10 kg, respectively. Mean change in pre-sCr to 24 and 48 hours was –6.9 ± 32.8 and –0.2 ± 22.8 μmol L^–1, respectively (<em>p</em> &gt; 0.05). sCr increased &gt; 26 μmol L^–1 in eight dogs at 24 hours and in an additional four dogs at 48 hours. Twelve dogs (7.3%) were classified with AKI: one grade 2 AKI (sCr 175 μmol L^–1) and 11 as grade 1 (sCr increase &gt; 26 μmol L^–1 but within reference range). In addition, four of these dogs had oliguria in the first 24 hours postoperatively. Hypotension occurred frequently (67.9%) and along with female sex was significantly associated with AKI.</div></div><div><h3>Conclusions and clinical relevance</h3><div>Perioperative AKI may be a common complication of elective desexing surgery in dogs. Potential risk factors include hypotension and female sex.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101149"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective airway management strategy for tracheal resection in a dog with cervical tracheal stenosis","authors":"Maria Isabel Gomez-Martinez,&nbsp;Lauren Brown","doi":"10.1016/j.vaa.2025.10.010","DOIUrl":"10.1016/j.vaa.2025.10.010","url":null,"abstract":"<div><div>A female Border Collie, aged 1 year and weighing 21.8 kg, was referred for surgical correction of a cervical tracheal stenosis located at the level of the sixth cervical vertebra. The stenosis was thought to result from an intubation injury caused by endotracheal cuff inflation 1 month earlier during an ovariohysterectomy. Premedication consisted of intravenous dexmedetomidine (2 μg kg^–1) and methadone (0.2 mg kg^–1). Anaesthesia was induced with intravenous propofol to effect and maintained with a variable-rate propofol infusion (0.1–0.3 mg kg^–1 minute^–1) and dexmedetomidine infusion (0.5 μg kg^–1 hour^–1). After initial intubation cranial to the stenosis with an 11 mm cuffed endotracheal tube (ETT), volume-controlled ventilation was established. Intraoperative endoscopy confirmed the location and severity of the stenosis. Reintubation was attempted with progressively smaller sterile ETTs; a 5.5 mm ETT was successfully advanced through the stenosis using a sterile bougie and extended intraorally with an elbow connector. After surgical exposure of the trachea, two tracheal rings were resected and a second sterile 5.5 mm ETT was placed under sterile conditions into the caudal trachea to maintain ventilation across the surgical field. An arterial blood gas analysis performed at this stage was unremarkable. Two additional cranial tracheal rings were resected, and a retrograde bougie-guided reintubation was performed to place a final 8.0 mm ETT across the anastomosis. An intraoperative leak test confirmed the integrity of the repair, and final endoscopy demonstrated a patent airway with no residual stenosis or haemorrhage. The dog recovered uneventfully. This case illustrates a staged and flexible airway management strategy using progressively smaller sterile tubes, bougie guidance and intraoperative endoscopy to maintain effective ventilation during complex tracheal surgery in dogs.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101154"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145696361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided cervical plexus associated block in dogs: A preliminary cadaveric study","authors":"Elisa Silvia D’Urso ,&nbsp;Chiara De Gennaro ,&nbsp;Giuliano Ravasio","doi":"10.1016/j.vaa.2025.09.001","DOIUrl":"10.1016/j.vaa.2025.09.001","url":null,"abstract":"<div><h3>Objectives</h3><div>To describe the ultrasonographic anatomy of the neck region in dogs and to determine the feasibility of an injection targeted to the cervical plexus.</div></div><div><h3>Study design</h3><div>Prospective cadaveric study.</div></div><div><h3>Animals</h3><div>A group of six mixed-breed mesocephalic dog cadavers.</div></div><div><h3>Methods</h3><div>Cadavers were assigned to a size category according to body weight (small, ≤10 kg; medium, 10.1–24 kg; large, &gt; 24.1 kg) and placed in lateral recumbency. A linear probe was placed over the wing of the atlas perpendicular to the spine and slid caudally to identify the transverse process of the fourth cervical vertebra. A 22 gauge, 70 mm spinal needle was introduced <em>in-plane</em> and advanced in a dorso-ventral direction, reaching the cervical fascia (CF). According to the size category, 2.5 mL, 5 mL or 10 mL of 0.15% methylene blue was injected within the CF and between the intertransversarius ventralis and longus colli muscles. Each cadaver was injected bilaterally. Staining of the second (C2), third (C3) and fourth (C4) cervical ventral branches was assessed by anatomical dissection.</div></div><div><h3>Results</h3><div>Each size category included two cadavers: 8 kg and 10 kg in the small category; 15 kg and 19 kg in the medium category; and 26 kg and 37 kg in the large category. Nerve staining resulted only from injection within the CF. In all cadavers, 100% of the ventral rami of the second (12/12), third (12/12) and fourth (12/12) cervical nerves were stained circumferentially for &gt; 2 cm. In the smallest cadaver, the dye reached the atlas cranially.</div></div><div><h3>Conclusions and clinical relevance</h3><div>The described injection within the CF stained the cervical plexus and appears a feasible locoregional technique in dogs.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101137"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidural injection of combined steroid and local anaesthetic for lumbosacral stenosis pain in a cat","authors":"Francesco Aprea,&nbsp;Miguel Omaña","doi":"10.1016/j.vaa.2025.09.005","DOIUrl":"10.1016/j.vaa.2025.09.005","url":null,"abstract":"","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101141"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of pulse pressure variation, stroke volume variation and plethysmography variability index for prediction of fluid responsiveness in anesthetized and mechanically ventilated dogs: a systematic review and meta-analysis","authors":"Pablo A. Donati ,&nbsp;Lisa Tarragona ,&nbsp;Ignacio Sandez Cordero ,&nbsp;Juan V.A. Franco ,&nbsp;Camila Escobar Liquitay ,&nbsp;Diego A. Portela ,&nbsp;Joaquín Araos ,&nbsp;Francesco Staffieri ,&nbsp;Pablo E. Otero","doi":"10.1016/j.vaa.2025.10.006","DOIUrl":"10.1016/j.vaa.2025.10.006","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the diagnostic accuracy of pulse pressure variation (PPV), plethysmographic variability index (PVI) and stroke volume variation (SVV) for predicting fluid responsiveness in dogs.</div></div><div><h3>Study design</h3><div>Systematic review and meta-analysis of diagnostic test accuracy studies.</div></div><div><h3>Animals</h3><div>Anesthetized dogs undergoing surgery, in critical care, or in experimental settings.</div></div><div><h3>Methods</h3><div>The study protocol was registered in Open Science Framework (<span><span>https://doi.org/10.17605/OSF.IO/4DBGP</span><svg><path></path></svg></span>). Databases (Medline, Embase, LILACS, Web of Science and Scopus) were searched from inception to 14 April 2025. Study quality was assessed using standardized criteria. Pooled sensitivity and specificity were calculated using a bivariate random-effects model. Likelihood ratios (LR), diagnostic odds ratios (DOR) and summary receiver operating characteristic (sROC) curves were generated. Confidence intervals (CIs) were calculated.</div></div><div><h3>Results</h3><div>Risk of bias was high in all studies of PPV, PVI and SVV. In four clinical PPV studies, sensitivity was 0.88 (95% CI: 0.65–0.97), specificity 0.97 (95% CI: 0.83–0.99), LR+ 30.99 (95% CI: 5.25–182.85), LR− 0.11 (95% CI: 0.02–0.40) and DOR 263 (95% CI: 26–1890). In five experimental PPV studies, sensitivity was 0.78 (95% CI: 0.64–0.87), specificity 0.83 (95% CI: 0.70–0.91), LR+ 4.63 (95% CI: 2.41–8.88), LR− 0.27 (95% CI: 0.16–0.46) and DOR 17 (95% CI: 6–48). For PVI (five studies), sensitivity was 0.83 (95% CI: 0.75–0.89), specificity 0.85 (95% CI: 0.78–0.90) and DOR 29 (95% CI: 13–64). For SVV (10 studies), sensitivity was 0.77 (95% CI: 0.69–0.84), specificity 0.81 (95% CI: 0.68–0.89) and DOR 14 (95% CI: 6–32). The sROC curve for clinical PPV showed wide prediction and CI.</div></div><div><h3>Conclusions and clinical relevance</h3><div>PPV, PVI and SVV show moderate to high diagnostic accuracy for predicting fluid responsiveness in dogs, with clinical PPV performing best. However, findings are limited by low precision and high risk of bias.</div></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":"53 1","pages":"Article 101150"},"PeriodicalIF":1.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145530954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}