Veterinary anaesthesia and analgesia最新文献

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Air-test for assessing gas exchange and the potential benefit of alveolar recruitment manoeuvre in anaesthetized dogs. 评估麻醉犬肺泡恢复运动的气体交换和潜在益处的空气试验。
IF 1.9 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-26 DOI: 10.1016/j.vaa.2025.07.010
Ignacio Sández, Pablo A Donati, Diego A Portela, Joaquín Araos
{"title":"Air-test for assessing gas exchange and the potential benefit of alveolar recruitment manoeuvre in anaesthetized dogs.","authors":"Ignacio Sández, Pablo A Donati, Diego A Portela, Joaquín Araos","doi":"10.1016/j.vaa.2025.07.010","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.07.010","url":null,"abstract":"<p><strong>Objective: </strong>To determine the use of Air-Test in ventilated, anaesthetized dogs for evaluating oxygen uptake and to determine its potential utility in guiding the decision to perform an alveolar recruitment manoeuvre (ARM).</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Animals: </strong>A total of 25 client-owned dogs undergoing general anaesthesia.</p><p><strong>Methods: </strong>Dogs were included if volume-controlled ventilation was performed, the dogs underwent an Air-Test and reliable haemoglobin oxygen saturation (SpO<sub>2</sub>) readings ≥ 99% with an inspired oxygen fraction (FiO<sub>2</sub>) 0.5 were available. Exclusion criteria included laparoscopic surgery, patient-ventilator asynchrony or haemodynamic instability. The Air-Test consisted of a reduction in FiO<sub>2</sub> to 0.21 for 4 minutes while monitoring SpO<sub>2</sub>. A positive Air-Test result was defined as SpO<sub>2</sub> < 96% during this period. Positive cases underwent sustained inflation ARMs with adjustments to positive end-expiratory pressure. Haemodynamic variables, gas exchange and static compliance (C<sub>st</sub>) were recorded pre-Air-Test, PaO<sub>2</sub>/FiO<sub>2</sub> ratio was calculated offline. Data from dogs with positive and negative Air-Test results were compared and they are shown as mean ± standard deviation; p < 0.05.</p><p><strong>Results: </strong>Of 835 records, 25 met the inclusion criteria. Positive Air-Tests occurred in 10 dogs (40%) and negative in 15 (60%). The baseline PaO<sub>2</sub>/FiO<sub>2</sub> ratio was 364 ± 39.6 mmHg (48.4 ± 5.1 kPa) and 510 ± 65 mmHg (67.8 ± 8.6 kPa) in the Air-Test-positive and -negative animals, respectively (p < 0.001). The C<sub>st</sub> and PaO<sub>2</sub>/FiO<sub>2</sub> increased significantly after ARM in Air-Test-positive dogs (p < 0.001 and p = 0.02, respectively). No differences were observed in the remaining variables.</p><p><strong>Conclusions and clinical relevance: </strong>A positive Air-Test was associated with a lower PaO<sub>2</sub>/FiO<sub>2</sub> ratio and in these dogs, an ARM was associated with increased C<sub>st</sub> and PaO<sub>2</sub>/FiO<sub>2</sub> ratio, indicating the potential of this noninvasive technique for assessing oxygenation and monitoring changes in response to ARM in mechanically ventilated dogs.</p>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blind digital orotracheal intubation in two dogs with difficult glottis visualization. 盲指口气管插管治疗两只声门显像困难的狗。
IF 1.9 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-25 DOI: 10.1016/j.vaa.2025.07.009
Hyunseok Kim, Won-Gyun Son, Inhyung Lee
{"title":"Blind digital orotracheal intubation in two dogs with difficult glottis visualization.","authors":"Hyunseok Kim, Won-Gyun Son, Inhyung Lee","doi":"10.1016/j.vaa.2025.07.009","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.07.009","url":null,"abstract":"<p><p>This report describes two cases of dogs in which a blind digital intubation technique was successfully used to manage difficult airways. A 9-year-old, 4.9 kg castrated male Poodle dog with history of cough and submandibular subcutaneous mass and a 13-year-old, 5.7 kg castrated male Poodle dog with dyspnoea and stridor were referred for computed tomography. In both dogs, a mass obstructing the glottis was identified following induction of anaesthesia, rendering it impossible to visualize the airway with laryngoscope use. Oxygen supplementation by face mask was ineffective and hypoxaemia worsened during repeated attempts to secure the airway. To facilitate digital intubation, the operator's nondominant index finger was introduced into the mouth, displacing the mass to access the epiglottis and palpate the glottis. The endotracheal tube was then inserted into the trachea with digital guidance, resulting in successfully secured airways in both dogs. Digitally facilitated intubation has not been described in detail or studied in small animal practice, although the technique is performed in larger animal species and in human medicine. As digital palpation provides tactile perception of key structures, blind digital intubation can be a valuable approach to facilitate intubation in dogs when direct visualization is obscured and endoscopy equipment not readily available.</p>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of approach, volume and morphometry on dye spread to the quadratus lumborum plane in canine cadavers. 入路、体积和形态学对犬腰方肌平面染料扩散的影响。
IF 1.9 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-22 DOI: 10.1016/j.vaa.2025.07.007
Marco Aurélio Camargo Fontanela, Marina Moresco, Gilberto Serighelli-Júnior, Marcello Machado, Fabiano Montiani-Ferreira, Juan Carlos Duque Moreno
{"title":"Effect of approach, volume and morphometry on dye spread to the quadratus lumborum plane in canine cadavers.","authors":"Marco Aurélio Camargo Fontanela, Marina Moresco, Gilberto Serighelli-Júnior, Marcello Machado, Fabiano Montiani-Ferreira, Juan Carlos Duque Moreno","doi":"10.1016/j.vaa.2025.07.007","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.07.007","url":null,"abstract":"<p><strong>Objective: </strong>To compare dye spread after injection in the quadratus lumborum plane (QLP) via transmuscular and lateral approaches with different volumes in canine cadavers.</p><p><strong>Study design: </strong>Cadaveric, experimental, prospective study.</p><p><strong>Animals: </strong>A group of 58 canine cadavers.</p><p><strong>Methods: </strong>Cadavers were classified by body mass as small (S, < 10 kg), medium (M, 10-20 kg) or large (L, > 20 kg). Morphometric data (mass, body condition score, axial length, abdominal and thoracic circumference) were recorded. Ultrasound-guided QLP injections with 0.15, 0.3 and 0.6 mL kg<sup>-1</sup> of 0.1% methylene blue were performed via transmuscular or lateral approaches on both hemiabdomens. Craniocaudal and dorsoventral dye spread, the number of stained ventral branches of thoracolumbar spinal nerves (VBSNs) and whether the sympathetic trunk was stained were evaluated. Technique and dissection times, along with visibility scores for reference structures, needle and the injected solution within the QLP were recorded. Statistical analysis included two-way analysis of variance, Kruskal-Wallis, Pearson correlation and multiple regression tests, with significance set at p < 0.050.</p><p><strong>Results: </strong>Morphometric variables influenced only the craniocaudal spread (p < 0.001). Craniocaudal spread did not differ significantly between approaches (p = 0.766) but was significantly influenced by volume (p < 0.002). However, greater craniocaudal spread did not result in an increased number of stained VBSNs (p = 0.488). The number of VBSNs stained was lower with 0.15 mL kg<sup>-1</sup> (p < 0.013), with no differences observed between 0.3 and 0.6 mL kg<sup>-1</sup> (p = 0.488). The most frequently stained VBSNs were L2, L3 and L1, in that order.</p><p><strong>Conclusions and clinical relevance: </strong>There were no significant differences in dye spread between transmuscular and lateral approaches. Injectate volume affects spread, but volumes > 0.3 mL kg<sup>-1</sup> do not increase the number of stained VBSNs. Morphometric variables do not affect the number of stained VBSNs.</p>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144837952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ephedrine overdose in a cat. 猫体内麻黄碱过量。
IF 1.9 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-21 DOI: 10.1016/j.vaa.2025.07.008
Matthew Gurney, Elspeth Lederer, Tristan Merlin
{"title":"Ephedrine overdose in a cat.","authors":"Matthew Gurney, Elspeth Lederer, Tristan Merlin","doi":"10.1016/j.vaa.2025.07.008","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.07.008","url":null,"abstract":"","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repeated balanced anesthesia in a juvenile sable antelope (Hippotragus niger) for diagnostic imaging and orthopedic interventions in a hospital setting. 反复平衡麻醉的幼貂羚羊(黑斑羚)诊断成像和矫形干预在医院设置。
IF 1.9 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-18 DOI: 10.1016/j.vaa.2025.07.006
Chelsea Conner, Mauricio L Lepiz, Courtney Baetge, Alexis Fichtel, Kati G Glass, Keila K Ida
{"title":"Repeated balanced anesthesia in a juvenile sable antelope (Hippotragus niger) for diagnostic imaging and orthopedic interventions in a hospital setting.","authors":"Chelsea Conner, Mauricio L Lepiz, Courtney Baetge, Alexis Fichtel, Kati G Glass, Keila K Ida","doi":"10.1016/j.vaa.2025.07.006","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.07.006","url":null,"abstract":"<p><p>The drug protocol and complications of 10 episodes of balanced anesthesia over 50 days for diagnostic imaging and orthopedic procedures in a captive female sable antelope are described. The antelope was initially admitted for lameness assessment of the right thoracic limb and admitted a second time for further lameness evaluation (right thoracic and pelvic limbs). Age and body weight ranged 5-6 months and 40-47 kg, respectively, between admissions. For the first anesthetic (day 1), after 4-6 hours of fasting (free access to water), the antelope was administered intramuscular medetomidine-vatinoxan (0.02 mg kg<sup>-1</sup>), midazolam (0.3 mg kg<sup>-1</sup>), ketamine (2 mg kg<sup>-1</sup>) and butorphanol (0.2 mg kg<sup>-1</sup>). Orotracheal intubation was performed 13 minutes after injection and followed by 45 minutes of sevoflurane (approximately 1% expired concentration; Fe'Sevo). Naloxone, atipamezole and flumazenil were administered to hasten recovery. For the nine additional anesthetics (days 35-50), intravenous premedication [midazolam (0.1-0.2 mg kg<sup>-1</sup>), combined with butorphanol (0.17 mg kg<sup>-1</sup>) for the second anesthetic] and anesthetic induction [ketamine (1.7-3.0 mg kg<sup>-1</sup>) and propofol (0.7-2.7 mg kg<sup>-1</sup>)] were followed by sevoflurane for maintenance (Fe'Sevo 1.22-2.17% for 40-90 minutes), delivered through an endotracheal tube (8.0-8.5 mm internal diameter). Tracheal extubation was performed 3-18 minutes after sevoflurane discontinuation. Morphine (0.1-0.2 mg kg<sup>-1</sup>) and saline (6-10 mL) were injected once daily through an epidural catheter (days 38-47). Complications during anesthesia included hypercapnia (10/10 anesthetics), hypothermia (9/10), hypotension (8/10), hypoglycemia (1/10), ruminal tympany (1/10) and regurgitation (1/10). Owing to the lack of response to treatment and grave prognosis, euthanasia was performed. Postmortem findings included chronic-active fibrinosuppurative polyarthritis of the right femoropatellar and metacarpophalangeal joints, necrosuppurative pyelitis and laryngeal petechiation. This case is described as a resource for anesthesia of juvenile antelopes in a hospital setting.</p>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of ketamine on the minimum anesthetic concentration of isoflurane in chickens (Gallus gallus domesticus). 氯胺酮对鸡异氟醚最低麻醉浓度的影响。
IF 1.9 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-17 DOI: 10.1016/j.vaa.2025.07.005
André Escobar, Brighton T Dzikiti, Kurt Roman, Alexandria Rogers, Jill K Maney
{"title":"Effects of ketamine on the minimum anesthetic concentration of isoflurane in chickens (Gallus gallus domesticus).","authors":"André Escobar, Brighton T Dzikiti, Kurt Roman, Alexandria Rogers, Jill K Maney","doi":"10.1016/j.vaa.2025.07.005","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.07.005","url":null,"abstract":"<p><strong>Objective: </strong>To assess the effects of two continuous intravenous (IV) infusion dose rates of ketamine on the minimum anesthetic concentration (MAC) of isoflurane in chickens.</p><p><strong>Study design: </strong>Prospective, randomized, blinded, experimental crossover design.</p><p><strong>Animals: </strong>A group of eight adult ISA Brown hens weighing 2.1 ± 0.19 kg.</p><p><strong>Methods: </strong>Anesthesia was induced and maintained with isoflurane in oxygen and chickens were mechanically ventilated. Body temperature and partial pressure of end-expired carbon dioxide were maintained between 40 and 41 °C and 30 and 40 mmHg (4-5.3 kPa). Isoflurane MAC was determined using electrical stimulation and the bracketing technique. Subsequently, a bolus of low (LD) or high (HD) dose ketamine (5 or 10 mg kg<sup>-1</sup> IV) was injected into the brachial vein followed by a constant rate IV infusion (5 or 10 mg kg<sup>-1</sup> hour<sup>-1</sup>, respectively), with a 1 week washout period between treatments. Isoflurane MAC was determined again approximately 1.5 (T1.5) and 3 hours (T3) after bolus injections. Adverse events and time to extubation were recorded. Data analyses consisted of a mixed-effects model for repeated measures (MAC data).</p><p><strong>Results: </strong>Isoflurane MAC was 1.51 ± 0.18% (mean ± standard deviation). Isoflurane MAC at T1.5 and T3 was 1.45 ± 0.16% and 1.53 ± 0.15% (LD) and 1.42 ± 0.24% and 1.46 ± 0.23% (HD). Isoflurane MAC values during LD [(T1.5) p = 0.857 and (T3) p = 0.995] and HD [(T1.5) p = 0.797 and (T3) p = 0.974] ketamine infusion were not different from baseline. Extubation times after isoflurane discontinuation was 12 ± 9 minutes for the LD and 14 ± 5 minutes for the HD treatment. Overall, four animals (both treatments) developed an obstructive mucous plug in the endotracheal tube.</p><p><strong>Conclusions and clinical relevance: </strong>Ketamine did not change isoflurane MAC in chickens. Chickens anesthetized with isoflurane and ketamine should be monitored for endotracheal tube obstruction.</p>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiation exposure during ultrasound- and fluoroscopy-guided spinal interventional pain management procedures in dogs: a retrospective analysis in a single institution. 在超声和透视引导下犬脊柱介入疼痛管理过程中的辐射暴露:单一机构的回顾性分析。
IF 1.9 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-17 DOI: 10.1016/j.vaa.2025.07.004
Roger Medina-Serra, Eliseo Belda, Patricia López-Abradelo, Aurora Zoff, Sandra Sanchís-Mora
{"title":"Radiation exposure during ultrasound- and fluoroscopy-guided spinal interventional pain management procedures in dogs: a retrospective analysis in a single institution.","authors":"Roger Medina-Serra, Eliseo Belda, Patricia López-Abradelo, Aurora Zoff, Sandra Sanchís-Mora","doi":"10.1016/j.vaa.2025.07.004","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.07.004","url":null,"abstract":"<p><strong>Objective: </strong>To quantify C-arm-registered radiation exposure during ultrasound- and fluoroscopy-guided spinal interventional pain management in dogs, and to measure operator-based radiation levels to identify discrepancies between delivered and received dose.</p><p><strong>Study design: </strong>A retrospective observational study.</p><p><strong>Animals: </strong>A total of 82 canine spinal interventional pain management procedures performed at a single referral institution.</p><p><strong>Methods: </strong>Radiation data [dose-area product (Gy·cm<sup>2</sup>) and absorbed dose (mGy)] were collected from a mobile C-arm fluoroscopy system for procedures conducted from September 2020 to August 2024. Effective dose (mSv) was calculated using a standard conversion factor applied to dose-area product (Gy·cm<sup>2</sup>). Operator exposure was monitored via thermoluminescent dosimeters (TLDs) placed at chest level and at the C-arm arc. TLD readings were retrieved quarterly through the Public Health England/UK Health Security Agency databases. The Shapiro-Wilk test was used to assess normality, and data were expressed as median (minimum-maximum) or mean ± standard deviation, as appropriate.</p><p><strong>Results: </strong>The median absorbed dose for all spinal interventions was 3.97 (0.07-25.8) mGy. The corresponding median dose-area product and effective dose was 0.63 (0.01-4.12) Gy·cm<sup>2</sup> and 0.15 (0.002-0.95) mSv, respectively. Procedural radiation exposure lay near the lower end of reported human ranges and operator TLD readings remained below detection thresholds despite cumulative procedural doses exceeding these levels.</p><p><strong>Conclusions and clinical relevance: </strong>Ultrasound- and fluoroscopy-guided spinal interventional pain management in dogs resulted in relatively low radiation exposure levels for both animals and operators. Incorporating ultrasound aligns with the 'as low as reasonably achievable' principle, helping reduce fluoroscopy time and associated risks. These findings support the development of targeted radiation safety protocols for veterinary interventional procedures and underscore the importance of continued operator training and dosimetry monitoring.</p>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the ratio of arterial partial pressure of oxygen to inspired oxygen fraction and dynamic compliance following anesthetic induction for predicting postanesthetic hypoxemia in dogs. 评估麻醉诱导后动脉血氧分压与吸入氧分数之比及动态顺应性预测犬麻醉后低氧血症。
IF 1.9 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-10 DOI: 10.1016/j.vaa.2025.07.003
Minha Kim, Taehoon Sung, Changhoon Nam, Inhyung Lee, Won-Gyun Son
{"title":"Evaluating the ratio of arterial partial pressure of oxygen to inspired oxygen fraction and dynamic compliance following anesthetic induction for predicting postanesthetic hypoxemia in dogs.","authors":"Minha Kim, Taehoon Sung, Changhoon Nam, Inhyung Lee, Won-Gyun Son","doi":"10.1016/j.vaa.2025.07.003","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.07.003","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate correlation between postanesthetic induction ratio of arterial partial pressure of oxygen to inspired oxygen fraction (PaO<sub>2</sub>:FIO<sub>2</sub>) and dynamic compliance (C<sub>dyn</sub>) with postanesthetic hypoxemia [PaO<sub>2</sub> < 80 mmHg (10.7 kPa)] in mechanically ventilated dogs, and to compare PaO<sub>2</sub>:FIO<sub>2</sub> and C<sub>dyn</sub> for predicting postanesthetic hypoxemia.</p><p><strong>Study design: </strong>Retrospective, single-cohort, observational study.</p><p><strong>Animals: </strong>A total of 168 dogs anesthetized with isoflurane under pressure-controlled ventilation.</p><p><strong>Methods: </strong>Postinduction arterial blood gas (ABG) analysis was performed 5-40 minutes postintubation and following postextubation (room-air). C<sub>dyn</sub> values were matched to the nearest postinduction ABG measurement (within 15 minutes). PaO<sub>2</sub>:FIO<sub>2</sub> and C<sub>dyn</sub> values were categorized using thresholds of 300 mmHg (40.0 kPa) and 400 mmHg (53.3 kPa), and 1.0 and 1.5 mL cmH<sub>2</sub>O<sup>-1</sup> kg<sup>-1</sup>. Linear-by-linear association was used to evaluate PaO<sub>2</sub>:FIO<sub>2</sub> and C<sub>dyn</sub> with the prevalence of postanesthetic hypoxemia. Diagnostic accuracy of these variables was assessed using receiver operating characteristic (ROC) curve analysis. Optimal cut-off values for distinguishing hypoxemia were determined using the empirical quantile bootstrap method (fixed sensitivity of 95%).</p><p><strong>Results: </strong>Postanesthetic hypoxemia was observed in 22/168 dogs. Lower postinduction PaO<sub>2</sub>:FIO<sub>2</sub> (p = 0.033) and C<sub>dyn</sub> (p = 0.002) values were associated with a significantly higher prevalence of postanesthetic hypoxemia. The area under the ROC curve (AUC) of PaO<sub>2</sub>:FIO<sub>2</sub> {0.696 [95% confidence interval (CI): 0.599-0.807]} and C<sub>dyn</sub> [0.716 (95% CI 0.602-0.824)] exhibited good (AUC 0.6-0.7) to satisfactory (AUC 0.7-0.8) diagnostic accuracy, with no significant difference between variables (p = 0.432). Optimal cut-off values were 332.80 mmHg (44.4 kPa) (95% CI 274.41-374.52 mmHg, 36.6-49.9 kPa) for PaO<sub>2</sub>:FIO<sub>2</sub> and 1.01 (95% CI 0.86-1.13) mL cmH<sub>2</sub>O<sup>-1</sup> kg<sup>-1</sup> for C<sub>dyn</sub>.</p><p><strong>Conclusions and clinical relevance: </strong>Postanesthetic hypoxemia was more frequently observed in dogs with low postinduction PaO<sub>2</sub>:FIO<sub>2</sub> and C<sub>dyn</sub>. These variables had good to satisfactory diagnostic accuracy.</p>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between ejection fraction and shortening fraction in dogs, and diagnostic accuracy of shortening fraction in identifying normal and abnormal ventricular contraction. 犬射血分数与缩短分数的关系及缩短分数对正常和异常心室收缩的诊断准确性。
IF 1.4 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-04 DOI: 10.1016/j.vaa.2025.06.012
Manuel Martin-Flores, Mark Rishniw
{"title":"Relationship between ejection fraction and shortening fraction in dogs, and diagnostic accuracy of shortening fraction in identifying normal and abnormal ventricular contraction.","authors":"Manuel Martin-Flores, Mark Rishniw","doi":"10.1016/j.vaa.2025.06.012","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.06.012","url":null,"abstract":"<p><strong>Objective: </strong>To examine the relationship between shortening fraction and ejection fraction, and to calculate the diagnostic performance of shortening fraction in identifying normal, subnormal and supranormal ejection fractions in dogs.</p><p><strong>Study design: </strong>Reanalysis of prospective data.</p><p><strong>Animal population: </strong>A group of 224 dogs; 86 healthy, 96 with mitral valve disease, and 42 with other cardiac pathologies.</p><p><strong>Methods: </strong>Echocardiographic cineloops of right parasternal short- and long-axis (RPSA and RPLA) and left apical four-chamber (LA4C) views were analyzed by five experienced echocardiographers. Ejection fraction was measured using the Simpson's method of discs from RPLA and LA4C, and shortening fraction from RPSA with M-mode. Sensitivity, specificity, and positive and negative predictive values of shortening fraction for identifying a low, normal, or high ejection fraction for each volumetric method, and the diagnostic performance of the LA4C volumetric method against the RPLA volumetric method, were calculated.</p><p><strong>Results: </strong>Sensitivity and specificity to detect low ejection fraction were 92% and 93% (RPLA) and 71% and 91% (LA4C). The positive and negative predictive values for low ejection fraction were 55% and 99% (RPLA) and 46% and 97% (LA4C).</p><p><strong>Conclusions and clinical relevance: </strong>Shortening fraction was a robust indicator of ejection fraction in dogs, with high sensitivity and specificity for the detection of decreased left ventricular systolic function. Given its simplicity and despite its limitations, shortening fraction might be a valuable tool during perianesthetic examinations of dogs.</p>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rocuronium and sugammadex in neonatal and juvenile foals. 罗库溴铵和糖马酮在新生马驹和幼马驹中的应用。
IF 1.4 2区 农林科学
Veterinary anaesthesia and analgesia Pub Date : 2025-07-03 DOI: 10.1016/j.vaa.2025.06.010
Manuel Martin-Flores, Joaquin Araos, Robin D Gleed
{"title":"Rocuronium and sugammadex in neonatal and juvenile foals.","authors":"Manuel Martin-Flores, Joaquin Araos, Robin D Gleed","doi":"10.1016/j.vaa.2025.06.010","DOIUrl":"https://doi.org/10.1016/j.vaa.2025.06.010","url":null,"abstract":"","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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