Twin Research and Human Genetics最新文献_第3页

Maternal Characteristics in Natural and Medically Assisted Reproduction Dizygotic Twin Pregnancies. 自然和医学辅助生殖双卵双胎妊娠的母体特征。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-09-06 DOI: 10.1017/thg.2024.26

Nikki Hubers, Christian M Page, Lannie Ligthart, René Pool, Jouke-Jan Hottenga, Jenny van Dongen, Cornelis B Lambalk, Jennifer R Harris, Gonneke Willemsen, Dorret I Boomsma

{"title":"Maternal Characteristics in Natural and Medically Assisted Reproduction Dizygotic Twin Pregnancies.","authors":"Nikki Hubers, Christian M Page, Lannie Ligthart, René Pool, Jouke-Jan Hottenga, Jenny van Dongen, Cornelis B Lambalk, Jennifer R Harris, Gonneke Willemsen, Dorret I Boomsma","doi":"10.1017/thg.2024.26","DOIUrl":"https://doi.org/10.1017/thg.2024.26","url":null,"abstract":"Previous studies have shown that mothers of naturally conceived dizygotic (DZ) twins tend to be taller, older, and smoke more than mothers of naturally conceived monozygotic (MZ) twin and mothers of singletons. Here, we investigate whether mothers of naturally conceived DZ twins differ from mothers who conceived their DZ twins after medically assisted reproduction (MAR) in eight maternal traits related to fertility based on observational survey data. We include data from 33,648 mothers from the Netherlands Twin Register (NTR) and 1660 mothers of twins from the Norwegian Mother, Father and Child Cohort Study (MoBA). We contrast mothers of naturally conceived DZ twins with mothers of MAR DZ twins. Next, we further segment the MAR group into mothers who underwent hormonal induction of ovulation but not in vitro fertilization (IVF) and those who IVF twins, comparing them both to each other and against the mothers of naturally conceived DZ twins. Mothers of naturally conceived DZ twins smoke more often, differ in body composition, have a higher maternal age and have more offspring before the twins than mothers of MZ twins. Compared to MAR DZ twin mothers, mothers of naturally conceived DZ twins have fewer miscarriages, lower maternal age and increased height, more offspring and are more often smokers. BMI before the twin pregnancy is similar in both natural and MAR DZ twin mothers. Mothers who received hormonal induction of ovulation (OI) have a lower maternal age, fewer miscarriages, and a higher number of offspring before their twin pregnancy than twin mothers who received IVF and/or intracytoplasmic sperm injection (ICSI) treatments. Our study shows that twin mothers are a heterogenous group and the differences between twin mothers should be taken into account in epidemiological and genetic research that includes twins.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zygosity Effects on Human Voice: Fundamental Frequency Analysis of Brazilian Twins' Speech. 基因遗传对人类语音的影响：巴西双胞胎语音的基频分析

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-10-02 DOI: 10.1017/thg.2024.33

Lilian C Luchesi, Julio C Cavalcanti, Tania K Lucci, Vinicius F David, Emma Otta, Patricia F Monticelli

{"title":"Zygosity Effects on Human Voice: Fundamental Frequency Analysis of Brazilian Twins' Speech.","authors":"Lilian C Luchesi, Julio C Cavalcanti, Tania K Lucci, Vinicius F David, Emma Otta, Patricia F Monticelli","doi":"10.1017/thg.2024.33","DOIUrl":"10.1017/thg.2024.33","url":null,"abstract":"Voice production can be influenced by interindividual variations related to genetic, physiological, behavioral, and several environmental factors. Here we examined the effect of zygosity on speaking fundamental frequency (F0) statistical descriptors. Our aims were: (1) to determine whether the genetic similarity between monozygotic (MZ) and dizygotic (DZ) twins affects F0 characteristics, and (2) to quantify the contribution of genetic factors to these characteristics. The study involved 79 same-sex twin pairs of Brazilian Portuguese speakers, comprising 65 MZ and 14 DZ twins, aged 18 to 66 years (31.7 ± 11.6 years), with 21 male and 58 female pairs. Participants were recorded while uttering a greeting phrase and the Brazilian Portuguese version of the 'Happy Birthday to You' song. Speech segments were analyzed using Praat free software, and F0 measures were automatically extracted in both Hertz and semitone scales. Statistical descriptors, including centrality, dispersion, and extreme values of F0 were examined, and the ACE model (i.e., total genetic effects, A; shared environmental influences, C; and nonshared environmental influences, E) was employed to estimate the additive effect;ts of monozygosity. As anticipated, we observed a zygosity effect on several F0 parameters, with more similarity between MZ twins compared to DZ twins. We discuss the genetic influences on F0 parameters and the absence of a monozygosity effect in two of them. Additionally, we briefly address potential biases associated with the selected measurement scale for statistical modeling. Finally, we explore the influence of genetic factors on F0 patterns, as well as environmental, life history and linguistic factors, particularly concerning F0 variation in speech.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"215-222"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic Influence on Social Support: A Twin Study. 遗传对社会支持的影响：双胞胎研究

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-10-02 DOI: 10.1017/thg.2024.32

Bodine M A Gonggrijp, Steve G A van de Weijer, Jenny van Dongen, Catrien C J H Bijleveld, Dorret I Boomsma

引用次数: 0

Common Genetic Influence on the Relationship Between Gaming Addiction and Attention Deficit Hyperactivity Disorder in Young Adults: A Twin Study. 青少年游戏成瘾与注意力缺陷多动障碍之间的共同遗传影响：一项双胞胎研究。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-10-28 DOI: 10.1017/thg.2024.29

Seol-Ah Lee, Yoon-Mi Hur

{"title":"Common Genetic Influence on the Relationship Between Gaming Addiction and Attention Deficit Hyperactivity Disorder in Young Adults: A Twin Study.","authors":"Seol-Ah Lee, Yoon-Mi Hur","doi":"10.1017/thg.2024.29","DOIUrl":"10.1017/thg.2024.29","url":null,"abstract":"Although the relationship between gaming addiction (GA) and attention deficit hyperactivity disorder (ADHD) is well established, the causal mechanism of this relationship remains ambiguous. We aimed to investigate whether common genetic and/or environmental factors explain the GA-ADHD relationship. We recruited 1413 South Korean adult twins (837 monozygotic [MZ], 326 same-sex dizygotic [DZ], and 250 opposite-sex DZ twins; mean age = 23.1 ± 2.8 years) who completed an online survey on GA and related traits. Correlational analysis and bivariate model-fitting analysis were conducted. Phenotypic correlation between GA and ADHD in the present sample was 0.55 (95% CI [0.51, 0.59]). Bivariate model-fitting analysis revealed that genetic variances were 69% (95% CI [64%, 73%]) and 68% (95% CI [63%, 72%]) for ADHD and GA respectively. The remaining variances (ADHD: 31%; GA: 32%) were associated with nonshared environmental variances, including measurement error. Genetic and nonshared environmental correlations between ADHD and GA were 0.68 (95% CI [0.62, 0.74]) and 0.22 (95% CI [0.13, 0.30]) respectively, which indicates that shared genes can explain 82% of the phenotypic correlation between ADHD and GA. Our study demonstrated that the ADHD-GA association was largely due to shared genetic vulnerability.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"198-203"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Sibling Patterns in the Educational Attainment of Hungarian Twins. 兄弟姐妹模式在匈牙利双胞胎教育成就中的作用。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-11-11 DOI: 10.1017/thg.2024.37

András Pári, Ágnes Engler

{"title":"The Role of Sibling Patterns in the Educational Attainment of Hungarian Twins.","authors":"András Pári, Ágnes Engler","doi":"10.1017/thg.2024.37","DOIUrl":"10.1017/thg.2024.37","url":null,"abstract":"Studies concerning twins with a sociological focus are scarce in Hungary as well as international research, although the number of twin births has increased dramatically worldwide. The raising and education of twins are tasks demanding special attention from both the family and institutions. In our study we examine these aspects, looking back from adulthood, using the narrow scope of the available data from research based on the 'Hungarostudy 2021' database (N total: 7000; n twins: 106). Our results, corresponding to the hypotheses of educational sociology, demonstrate how the relationships between family size and school career and increasing number of siblings reduces the chances of high educational attainment. A regression analysis confirmed that both the number of siblings and a later position in the birth order reduces the chance of obtaining a higher education. For the second child in a family, the chance of earning a university degree is reduced to to 0.743. The role of a large family concerning higher education showed a stronger relationship in the case of twins compared to nontwins. For twins, the sibling pattern has a decisive effect in educational attainment. Twins themselves have a 1.449 times higher chance of obtaining a higher education compared to nontwins (p = 0.101), and fraternal twins have half (0.517) the chance of obtaining a higher education compared to identical twins; but both results are not significant (p = 0.156).","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"231-240"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THG volume 27 issue 4-5 Cover. THG 第 27 卷第 4-5 期封面。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-12-20 DOI: 10.1017/thg.2024.45

引用次数: 0

Review of The Twin Children of the Holocaust: Stolen Childhood and the Will to Survive, by Nancy L. Segal - CORRIGENDUM. 回顾大屠杀的双胞胎孩子:被偷走的童年和生存的意志，南希·l·西格尔著-勘误表。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2023-12-01 DOI: 10.1017/thg.2023.47

Jeffrey M Craig

引用次数: 0

Tribute to Dr Milton Diamond: Twin Studies of Transsexuality/Twin Research Reviews: Loss of a Twin Brother (Recent Memoir); Oxytocin Adminstration During Twin Delivery; Models of Monochorionic Twinning; Twins' Brain Responses to Watching Films/Human Interest: Oldest Conjoined Twins Pass Away; Twins Discordant for Child Abuse; Twins Married to Twins; Rare Quadruplet Set Delivered; Questions of Coincidence; Reared-Apart Twin Valedictorians. 向米尔顿·戴蒙德博士致敬：变性的双胞胎研究/双胞胎研究评论：失去一个双胞胎兄弟（最近的回忆录）；双胎分娩时催产素的应用单绒毛膜孪生模型；双胞胎对观看电影/人类兴趣的大脑反应：最年长的连体双胞胎去世；虐待儿童的双胞胎不一致；双胞胎嫁给双胞胎；罕见四胞胎套装交付；巧合问题；分开的双胞胎毕业生代表。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-12-20 DOI: 10.1017/thg.2024.34

Nancy L Segal

{"title":"Tribute to Dr Milton Diamond: Twin Studies of Transsexuality/Twin Research Reviews: Loss of a Twin Brother (Recent Memoir); Oxytocin Adminstration During Twin Delivery; Models of Monochorionic Twinning; Twins' Brain Responses to Watching Films/Human Interest: Oldest Conjoined Twins Pass Away; Twins Discordant for Child Abuse; Twins Married to Twins; Rare Quadruplet Set Delivered; Questions of Coincidence; Reared-Apart Twin Valedictorians.","authors":"Nancy L Segal","doi":"10.1017/thg.2024.34","DOIUrl":"10.1017/thg.2024.34","url":null,"abstract":"A tribute to the life and career of Dr Milton Diamond, a leading figure in twin studies of transsexuality and gender identity, is presented. Dr Diamond is famous for revealing the truth about the unsuccessful effort to change a monozygotic male Canadian twin into a female, following accidental ablation of his penis during circumcision. A short summary of recent twin research on human sexuality and transsexuality, focused on Dr Diamond's contributions, is then presented. The tribute and overview are followed by research reviews involving the loss of a twin brother; oxytocin adminstration during twin delivery; models of monochorionic twinning; and twins' brain responses to watching films. The final section of this article covers topics of human interest, including the passing of the world's oldest conjoined twins; twins discordant for child abuse; twins married to twins; the delivery of a rare quadruplet set; questions of coincidence; and reared-apart twin valedictorians.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":"27 4-5","pages":"256-260"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Placental Vascular Anastamoses and Associated Pathologies in Dichorionic Twin Gestations. 二绒毛膜双胎妊娠的胎盘血管吻合及相关病理。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-11-07 DOI: 10.1017/thg.2024.35

Eesha Dave, Mert Ozan Bahtiyar, William Campbell, Raffaella Morotti, Katherine Kohari

引用次数: 0

Twin Data Support a Sensitive Period for Singing Ability. 双胞胎数据支持歌唱能力的敏感期

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-10-02 DOI: 10.1017/thg.2024.30

Daniel Yeom, Nick Haslam, Yi Ting Tan, Gary E McPherson, Sarah J Wilson

{"title":"Twin Data Support a Sensitive Period for Singing Ability.","authors":"Daniel Yeom, Nick Haslam, Yi Ting Tan, Gary E McPherson, Sarah J Wilson","doi":"10.1017/thg.2024.30","DOIUrl":"10.1017/thg.2024.30","url":null,"abstract":"As with many other musical traits, the social environment is a key influence on the development of singing ability. While the familial singing environment is likely to be formative, its role relative to other environmental influences such as training is unclear. We used structural equation modeling to test relationships among demographic characteristics, familial environmental variables (early and current singing with family), vocal training, and singing ability in a large, previously documented sample of Australian twins (N = 1163). Notably, early singing with family, and to a lesser extent vocal training, predicted singing ability, whereas current singing with family did not. Early familial singing also mediated the relationship between sex and singing ability, with men who sang less with family during childhood showing poorer ability. Bivariate twin models between early familial singing and singing ability showed the phenotypic correlation was largely explained by shared environmental influences. This raises the possibility of a sensitive period for singing ability, with sociocultural expectations around singing potentially differentiating the developmental trajectories of this skill for men and women.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"204-214"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0