Twin Research and Human Genetics最新文献_第2页

Perinatal Outcomes Following Selective Fetal Terminations of Complicated Monochorionic Pregnancies: Experience From a Referral Center in Southern Spain. 复杂单绒毛膜妊娠选择性终止胎儿后的围产期结局：来自西班牙南部转诊中心的经验。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-04-22 DOI: 10.1017/thg.2025.16

Melisa De Pauli, Pilar Carretero Lucena, Andrea Samper Girona, Olga Ocón Hernández, José Alejandro Ávila Cabreja, Francisca Sonia Molina

{"title":"Perinatal Outcomes Following Selective Fetal Terminations of Complicated Monochorionic Pregnancies: Experience From a Referral Center in Southern Spain.","authors":"Melisa De Pauli, Pilar Carretero Lucena, Andrea Samper Girona, Olga Ocón Hernández, José Alejandro Ávila Cabreja, Francisca Sonia Molina","doi":"10.1017/thg.2025.16","DOIUrl":"https://doi.org/10.1017/thg.2025.16","url":null,"abstract":"The objective of this study was to to describe perinatal outcomes in monochorionic twin pregnancies after selective fetal reduction using bipolar cord coagulation (BCC) or interstitial laser ablation (ILA). This retrospective cohort study included monochorionic twin pregnancies requiring selective fetal reduction between 2008 and 2023 at a referral center in Spain. Maternal and perinatal data were collected and analyzed to compare outcomes between BCC and ILA techniques. The primary outcome was the survival of the co-twin, while secondary outcomes included gestational age at delivery, the incidence of PPROM, birth weight and long-term neurodevelopmental outcomes. Eighty-four procedures were performed (30 ILA, 54 BCC). The overall co-twin survival rate was 80%, with BCC showing a higher survival rate (87%) compared to ILA (67%, p = .026). Fetal death before 24 weeks was more common in ILA (30%) than BCC (7.4%, p = .010). The mean gestational age at delivery was lower in BCC (36.6 weeks) than ILA (38.6 weeks, p = .021), and preterm delivery was more frequent in BCC (50%) compared to ILA (14%, p = .005). BCC seems to have a better overall survival than ILA in complicated monochorionic twins' selective terminations. However, we could not clarify whether this difference was due to the technique itself or the different gestational age at the time of the procedure as well as the specific indication.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"1-5"},"PeriodicalIF":1.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Twin Births in 42 Sub-Saharan African Countries from 1986 to 2016: Frequency, Trends and Factors of Variation. 1986年至2016年42个撒哈拉以南非洲国家的双胞胎出生：频率、趋势和变异因素。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-04-22 DOI: 10.1017/thg.2025.18

Adama Ouedraogo, Gilles Pison, Sophie le Coeur, Abdramane B Soura

{"title":"Twin Births in 42 Sub-Saharan African Countries from 1986 to 2016: Frequency, Trends and Factors of Variation.","authors":"Adama Ouedraogo, Gilles Pison, Sophie le Coeur, Abdramane B Soura","doi":"10.1017/thg.2025.18","DOIUrl":"https://doi.org/10.1017/thg.2025.18","url":null,"abstract":"Since the 1970s, twin birth rates have increased sharply in developed countries. In Africa, where the rate is the highest globally, its evolution and variation are poorly understood. This article aims to estimate the twinning rate in sub-Saharan African (SSA) countries throughout 1986-2016 and analyze its spatial, temporal, and ethnic variations. It also seeks to identify social and demographic factors associated with a high probability of twin births and outline a forecast of the twinning rate. We used data from 174 Demographic and Health Surveys from 42 countries. We supplemented them with the UN World Population Prospects (WPP). The twinning rate was calculated by reporting the number of twin births per thousand total births. We used logistic regression to analyze the factors associated with twin births. We projected the twinning rate based on WPP. The overall SSA twinning rate is 17.4 per 1000, but it has changed very little over time, and we expect it will grow a little between 2015 and 2050, increasing at most from 17.4 per 1000 to 18.4 per 1000. We also show significant differences in the twinning rate in SSA according to mother ethnicity. Most ethnic groups with high twinning rates belong to the large Bantu ethnic family. SSA remains the 'land of twins', with the twinning rate changing slowly. However, specific health policies must target twin births in SSA to address the public health challenges they present.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"1-17"},"PeriodicalIF":1.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Financial Stressors and Risk of Suicidal Behavior in a Swedish National Cohort. 瑞典国家队列的财务压力因素和自杀行为风险。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-04-22 DOI: 10.1017/thg.2025.19

Alexis C Edwards, Henrik Ohlsson, Jan Sundquist, Kristina Sundquist, Kenneth S Kendler

{"title":"Financial Stressors and Risk of Suicidal Behavior in a Swedish National Cohort.","authors":"Alexis C Edwards, Henrik Ohlsson, Jan Sundquist, Kristina Sundquist, Kenneth S Kendler","doi":"10.1017/thg.2025.19","DOIUrl":"https://doi.org/10.1017/thg.2025.19","url":null,"abstract":"Although financial stressors are implicated as risk factors for suicidal behavior, these associations might be confounded by other factors. Furthermore, a move toward high-risk subgroup definition is necessary. The authors used Swedish national registry data to examine the associations between receipt of social welfare, unemployment benefits, or early retirement (N = 627,745-2,260,753) with suicidal behavior in Cox proportional hazards models. They applied co-relative models to improve causal inference, and examined interactions with aggregate genetic risk for suicidality. All three exposures were associated with elevated suicidal behavior risk. Initial hazard ratios for suicide attempt ranged from 1.37-3.86, were similar for suicide death, and declined after controlling for psychopathology and time elapsed after exposure. Age at registration differentially impacted risk of suicidal behavior. Aggregate genetic liability for suicidality was associated with risk, but its effect was not moderated by financial stress. Financial stressors are associated with suicidal behavior risk even after controlling for psychopathology. Associations are attributable in part to familial confounding, though a potentially causal pathway was observed in most cases. Suicidality risk varied as a function of sex and age at exposure; these findings could be used to identify subgroups at high risk who warrant targeted prevention.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abstracts for the 47th Human Genetics Society of Australasia Annual Scientific Meeting, Gold Coast, Queensland, Australia, 10-13 August 2024. 第47届澳大利亚人类遗传学会年度科学会议，澳大利亚昆士兰黄金海岸，2024年8月10-13日。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-04-17 DOI: 10.1017/thg.2025.7

引用次数: 0

Capturing Gender Diversity in Twin Research. 捕捉双胞胎研究中的性别多样性。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-04-15 DOI: 10.1017/thg.2025.14

Will Conabere, Anja Ravine, Louise Bourchier, Sue Malta, Jessica Tyler, Shuai Li, John L Hopper, Ken C Pang

引用次数: 0

Abstracts from the 19th International Congress on Twin Studies, 26-28 September 2024. 第19届国际双胞胎研究大会摘要，2024年9月26-28日。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-04-14 DOI: 10.1017/thg.2025.12

引用次数: 0

Diagnostic Integrity of DSM Categorized Eating Disorders: Exploration of Alternative Methods of Classification and the Implications for Genetic Research - CORRIGENDUM. DSM分类饮食失调的诊断完整性：探索分类的替代方法和对遗传研究的影响-勘误表。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-04-14 DOI: 10.1017/thg.2025.20

Jessica Livney, Melissa Pehlivan, Nicholas G Martin, Sarah Maguire

引用次数: 0

Abstracts from the 19th International Congress on Twin Studies, 11-14 November 2021 - CORRIGENDUM. 第19届国际双胞胎研究大会摘要，2021年11月11日至14日-勘误表。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-03-28 DOI: 10.1017/thg.2025.13

引用次数: 0

The Excess Mortality Among Twins in the Dominican Republic and Haiti Through the Components of Age Under Five: A Comparative Study of Trends and Associated Factors. 多明尼加共和国和海地五岁以下双胞胎的超额死亡率：趋势和相关因素的比较研究。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-03-24 DOI: 10.1017/thg.2025.11

Adama Ouedraogo, David Jean Simon, Ann Kiragu, Nicole Estefany Aponte Cueto, Vénunyé Claude Kondo Tokpovi

{"title":"The Excess Mortality Among Twins in the Dominican Republic and Haiti Through the Components of Age Under Five: A Comparative Study of Trends and Associated Factors.","authors":"Adama Ouedraogo, David Jean Simon, Ann Kiragu, Nicole Estefany Aponte Cueto, Vénunyé Claude Kondo Tokpovi","doi":"10.1017/thg.2025.11","DOIUrl":"https://doi.org/10.1017/thg.2025.11","url":null,"abstract":"Despite the decline in mortality rates among children in developing countries, disparities persist between countries, particularly between twins and singletons. This study employed data from nine Demographic and Health Surveys in the Dominican Republic and Haiti to estimate and compare mortality rates for twins and singletons in categories of the under-5 age group (neonatal, postneonatal, and child mortality) and examine the factors associated with excess mortality among twins. From 1996 to 2013, the under-5 mortality rate (U5MR) for singletons in the Dominican Republic declined from 56‰ (95% CI [47, 64) to 30‰ (22-39) and from 108‰ (53-164) to 53‰ (16-89) among twins. In Haiti, between 1994 and 2016, the U5MR declined from 121‰ (109-133) to 77‰ (68-80) for singletons and from 432‰ (327-538) to 204‰ (149-260) among twins. The adjusted risk of neonatal death for twins is 1.4 (1.0-1.9) times higher than for singletons in the Dominican Republic, compared to a risk of 4.3 (3.5-5.3) times higher in Haiti. In the post-neonatal period, the mortality risk for twins in the Dominican Republic was 1.8 (1.0-3.1) times higher than that for singletons, 2.9 (2.3-3.8) in Haiti. The risk of death for twins was not significantly different from that for singletons in both the Dominican Republic and Haiti at ages 1-4 years. Low birth weight, lack of breastfeeding, absence of, or inadequate, antenatal care, noncesarean section birth, and high birth order were associated with excess mortality among twins in both countries.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"1-20"},"PeriodicalIF":1.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Experiences of Patients With Vanishing Twin Syndrome: A Mixed-Methods Exploration of Patient Satisfaction and Miscarriage Information. 双胎消失综合征患者的经历：患者满意度和流产信息的混合方法探索。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2025-03-21 DOI: 10.1017/thg.2025.10

Nichole M Cubbage, Nicholas Embleton, Carly Levy

{"title":"The Experiences of Patients With Vanishing Twin Syndrome: A Mixed-Methods Exploration of Patient Satisfaction and Miscarriage Information.","authors":"Nichole M Cubbage, Nicholas Embleton, Carly Levy","doi":"10.1017/thg.2025.10","DOIUrl":"https://doi.org/10.1017/thg.2025.10","url":null,"abstract":"Vanishing twin syndrome is a miscarriage of multiples where one or more fetuses 'vanishes' (i.e., partial or full resorption or via calcification) during pregnancy, often before detection via ultrasound. It affects 30-50% of multifetal pregnancies, with most cases resulting in full resorption within the first trimester. Despite its recognition since 1945 and rising occurrence in both natural and assisted pregnancies, standardized clinical guidelines remain inadequate, leading to inconsistent diagnosis, counseling, and communication from healthcare providers. This study examines the experiences of mothers and gestational carriers diagnosed with VTS, focusing on patient-provider communication, risks, and symptom disclosure. A global online survey collected qualitative and quantitative data from 153 participants across 17 countries. Results show that most patients with formal diagnoses experienced negative interactions with healthcare providers, with an average sentiment score of -0.7 (on a scale from -2 to 2). Over 53.4% rated their communication experience as -1, and the average satisfaction score for the amount of information received was 3.5/10. Additionally, 43% of respondents were not informed about chorionicity, a key factor affecting fetal outcomes. Significant discrepancies in care were observed across different countries. The findings highlight major gaps in patient-provider communication and inconsistent clinical practices regarding VTS. Addressing these issues through improved education, clearer protocols, and standardized guidelines could enhance patient experiences and decision-making. Future research should focus on provider training and evidence-based strategies to improve the management of VTS and other types of miscarriage and death of multiples during pregnancy and postpartum.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0