发布求助
文献互助 智能选刊 最新文献

Trends in parasitology最新文献

筛选
英文 中文
Shifting metabolism alters rRNA expression in malaria parasites. 代谢的改变改变了疟原虫的rRNA表达。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-02-24 DOI: 10.1016/j.pt.2026.01.014
Evi Hadjimichael, Kirk W Deitsch
{"title":"Shifting metabolism alters rRNA expression in malaria parasites.","authors":"Evi Hadjimichael, Kirk W Deitsch","doi":"10.1016/j.pt.2026.01.014","DOIUrl":"10.1016/j.pt.2026.01.014","url":null,"abstract":"<p><p>Malaria parasites display the unique property of expressing distinct ribosomal RNAs at different points in their transmission cycle. Couble et al. determined that derepression of the mosquito-specific rDNA loci is initiated by altered NAD<sup>+</sup>/nicotinamide (NAM) ratios, resulting from the metabolic shift that parasites undergo as they transition into the mosquito stages.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"158-159"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colorful parasites: an overlooked frontier in animal coloration research. 彩色寄生虫：动物色彩研究中一个被忽视的前沿。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-03-03 DOI: 10.1016/j.pt.2026.01.004
Ryota Hasegawa, Robert Poulin
{"title":"Colorful parasites: an overlooked frontier in animal coloration research.","authors":"Ryota Hasegawa, Robert Poulin","doi":"10.1016/j.pt.2026.01.004","DOIUrl":"10.1016/j.pt.2026.01.004","url":null,"abstract":"<p><p>The diverse coloration of animals has fascinated researchers over the past centuries. A growing body of evidence has documented the many functions of animal coloration, ranging from mate attraction to predator avoidance. Yet, the adaptive functions of parasite coloration have been largely neglected in this context, despite the fact that many parasites across diverse taxonomic groups exhibit colorful body patterns. In this opinion article, we discuss the potential adaptive functions of color in parasites. We first summarize some potential functions of parasite coloration based on an intensive review of the existing literature. We then propose several possible ecological, evolutionary, and biogeographical hypotheses regarding patterns in parasite coloration and outline future directions for this intriguing study frontier.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"162-172"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune interactions of entomopathogens with mosquito and tick vectors. 昆虫病原与蚊、蜱媒介的免疫相互作用。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-02-24 DOI: 10.1016/j.pt.2026.01.006
Yanhong Wang, Huimin Fu, Zhen Zou
{"title":"Immune interactions of entomopathogens with mosquito and tick vectors.","authors":"Yanhong Wang, Huimin Fu, Zhen Zou","doi":"10.1016/j.pt.2026.01.006","DOIUrl":"10.1016/j.pt.2026.01.006","url":null,"abstract":"<p><p>Entomopathogenic fungi and bacteria offer promising alternatives to chemical insecticides for controlling mosquitoes and ticks-key vectors of malaria and Lyme disease. However, their efficacy largely depends on immune interactions between pathogens and hosts. Here, we focus on mosquitoes and ticks as representative disease vectors and dissect conserved and divergent immune responses, from physical barriers to cellular defenses and key humoral pathways, with mechanistic insights informed by insect model systems. Furthermore, we elucidate diverse virulence and immune evasion strategies that enable pathogen infection. By synthesizing foundational and contemporary research, we examine the coevolutionary arms race between entomopathogens and mosquito and tick hosts, with the goal of translating these insights into next-generation strategies for vector control and public health protection.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"192-202"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Root-knot nematode genomics: what is coming soon? 根结线虫基因组学：即将到来的是什么？
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-02-24 DOI: 10.1016/j.pt.2026.01.007
Etienne G J Danchin
{"title":"Root-knot nematode genomics: what is coming soon?","authors":"Etienne G J Danchin","doi":"10.1016/j.pt.2026.01.007","DOIUrl":"10.1016/j.pt.2026.01.007","url":null,"abstract":"<p><p>Root-knot nematodes are among the most destructive plant parasites on Earth. Many aspects of their biology are fascinating, including their diverse reproductive modes, their extreme polyphagy, their unknown origin, and their sophisticated plant manipulation systems. Although genome analyses have illuminated certain points of their biology, recent advances in sequencing technologies have revealed some chromosomal idiosyncrasies. This includes unique telomere systems unparalleled in any other organism and complex holocentromere organisations. Evidence of polyploid hybrid genome structures in some of these species, with shared yet unknown parents, has redefined the way we need to interpret genome and expression data. It is timely to foresee new knowledge that can be gained by the adoption of the latest omics technologies by plant nematologists.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"173-182"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Irène landau: a life devoted to parasitology. ir<s:1>朗道：一生致力于寄生虫学。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-02-24 DOI: 10.1016/j.pt.2026.01.009
Irène Landau, Timothy Little, Érika Martins Braga
{"title":"Irène landau: a life devoted to parasitology.","authors":"Irène Landau, Timothy Little, Érika Martins Braga","doi":"10.1016/j.pt.2026.01.009","DOIUrl":"10.1016/j.pt.2026.01.009","url":null,"abstract":"","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"143-147"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147284979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A protein-based self-assembled nanoparticle provides an improved malarial vaccine. 一种基于蛋白质的自组装纳米颗粒提供了一种改进的疟疾疫苗。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-02-28 DOI: 10.1016/j.pt.2026.02.002
Matthew R Groves, Siyao Chen
{"title":"A protein-based self-assembled nanoparticle provides an improved malarial vaccine.","authors":"Matthew R Groves, Siyao Chen","doi":"10.1016/j.pt.2026.02.002","DOIUrl":"10.1016/j.pt.2026.02.002","url":null,"abstract":"<p><p>Shi et al. recently published a report leveraging the self-assembly of the Pdx1 and Pdx2 proteins as a vaccine platform. This elegant approach achieved complete sterile protection in mouse models, providing a promising avenue to accomplish the WHO's goal of eliminating malaria in at least 35 countries by 2030.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"160-161"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breaking the deadlock in antigen discovery for Leishmania vaccines. 打破利什曼原虫疫苗抗原发现的僵局。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-03-02 DOI: 10.1016/j.pt.2026.01.005
Wim Adriaensen, Nicky de Vrij, Thao-Thy Pham, Kris Laukens, Pieter Meysman, Paul M Kaye
{"title":"Breaking the deadlock in antigen discovery for Leishmania vaccines.","authors":"Wim Adriaensen, Nicky de Vrij, Thao-Thy Pham, Kris Laukens, Pieter Meysman, Paul M Kaye","doi":"10.1016/j.pt.2026.01.005","DOIUrl":"10.1016/j.pt.2026.01.005","url":null,"abstract":"<p><p>Despite the global burden of leishmaniasis, no licensed human vaccine exists. Vaccine antigens are typically based on in silico predictions or their immunogenicity in animal models and cured patients. T cell epitopes have only been mapped for fewer than 2% of over 8000 Leishmania proteins, with only ten proteins tested in clinical trials. Whether infected human phagocytes naturally present such antigens early on during infection, and prior to the onset of parasite-induced regulatory mechanisms, is unknown. We discuss why this is critical to the induction of protective immunity and argue that antigen availability can conclusively guide and accelerate vaccine candidate discovery. Here, emerging technologies, including immunopeptidomics, single-cell multiomics, and T cell receptor repertoire mapping, offer transformative opportunities to redefine Leishmania antigen discovery.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"183-191"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147345205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Engaging minds, building competence: case-based e-learning in parasitology. 参与思想，培养能力：基于案例的寄生虫学电子学习。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-02-28 DOI: 10.1016/j.pt.2026.01.003
Beata Kirk, Ghazanfar Abbas, Tanapan Sukee, Charles Gauci, Clare A Anstead, Julian Harris, Elisa K Bone, Abdul Jabbar
{"title":"Engaging minds, building competence: case-based e-learning in parasitology.","authors":"Beata Kirk, Ghazanfar Abbas, Tanapan Sukee, Charles Gauci, Clare A Anstead, Julian Harris, Elisa K Bone, Abdul Jabbar","doi":"10.1016/j.pt.2026.01.003","DOIUrl":"10.1016/j.pt.2026.01.003","url":null,"abstract":"<p><p>The COVID-19 pandemic reshaped parasitology education, exposing challenges in delivering laboratory-rich, experiential learning. Case-based e-learning (CBEL) emerged as a powerful solution, restoring engagement through authentic, adaptive, and interactive scenarios. Drawing on our recent experiences, we show how CBEL supports deeper reasoning, flexibility, development of competency, and preparedness for parasitic diseases.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"148-152"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural and regulatory principles underlying apicomplexan conoid function. 顶复锥体功能的结构和调节原理。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-02-06 DOI: 10.1016/j.pt.2026.01.002
Albert Tell I Puig, Dominique Soldati-Favre
{"title":"Structural and regulatory principles underlying apicomplexan conoid function.","authors":"Albert Tell I Puig, Dominique Soldati-Favre","doi":"10.1016/j.pt.2026.01.002","DOIUrl":"10.1016/j.pt.2026.01.002","url":null,"abstract":"<p><p>Zeng et al. and Qian et al. reveal in their cryogenic electron microscopy (cryo-EM) studies how apicomplexan parasites extensively remodel tubulin to construct the conoid, a specialized invasion organelle. Distinct microtubule assemblies integrate mechanical support, force generation, and secretion control, providing a structural framework that underpins parasite motility and host cell entry.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"153-155"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
With a little help from my friend: engaging CD44 facilitates Plasmodium falciparum invasion of erythrocytes. 在我朋友的帮助下参与CD44促进了恶性疟原虫对红细胞的侵袭。
IF 6.6 1区 医学
Trends in parasitology Pub Date : 2026-03-01 Epub Date: 2026-02-27 DOI: 10.1016/j.pt.2026.02.001
Laurent Rénia
{"title":"With a little help from my friend: engaging CD44 facilitates Plasmodium falciparum invasion of erythrocytes.","authors":"Laurent Rénia","doi":"10.1016/j.pt.2026.02.001","DOIUrl":"10.1016/j.pt.2026.02.001","url":null,"abstract":"<p><p>Merozoite invasion in erythrocytes is a complex process. Kongsomboonvech et al. identify the host transmembrane protein CD44 as a critical coreceptor that, when crosslinked, significantly enhances the ability of Plasmodium falciparum to invade human erythrocytes. It provides a molecular link between early parasite attachment and the final, essential invasion steps.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":"156-157"},"PeriodicalIF":6.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书