Rethinking parasitoid venoms: beyond immune suppression.

IF 6.6 1区医学 Q1 PARASITOLOGY

Trends in parasitology Pub Date : 2025-07-18 DOI:10.1016/j.pt.2025.07.005

Abraham Y Kpirikai, Nicholas M Bretz, Nathan T Mortimer

引用次数: 0

Abstract

Parasitoid wasp venoms are widely studied for their immunosuppressive properties. Work by Dong et al. expands the venom repertoire to include manipulation of host metabolites with the discovery of the Leptopilina-specific venom lipase (LVL). LVL is an active lipase that converts host lipids to support parasitoid embryogenesis following infection.

查看原文本刊更多论文

重新思考寄生虫毒液：超越免疫抑制。

寄生蜂毒液因其免疫抑制特性而被广泛研究。Dong等人的工作扩展了毒液的功能范围，包括操纵宿主代谢物，发现了leptopilina特异性毒液脂肪酶（LVL）。LVL是一种活性脂肪酶，可在感染后转化宿主脂质以支持类寄生物胚胎发生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Trends in parasitology 医学-寄生虫学

CiteScore

14.00

自引率

3.10%

发文量

148

审稿时长

6-12 weeks

期刊介绍： Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts. Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.