Translational Vision Science & Technology最新文献

{"title":"Anomaly Detection in Retinal OCT Images With Deep Learning-Based Knowledge Distillation.","authors":"Guilherme Aresta, Teresa Araújo, Ursula Schmidt-Erfurth, Hrvoje Bogunovic","doi":"10.1167/tvst.14.3.26","DOIUrl":"10.1167/tvst.14.3.26","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to develop a robust and general purpose artificial intelligence (AI) system that allows the identification of retinal optical coherence tomography (OCT) volumes with pathomorphological manifestations not present in normal eyes in screening programs and large retrospective studies.</p><p><strong>Methods: </strong>An unsupervised anomaly detection deep learning approach for the screening of retinal OCTs with any pathomorphological manifestations via Teacher-Student knowledge distillation is developed. The system is trained with only normal cases without any additional manual labeling. At test time, it scores how anomalous a sample is and produces localized anomaly maps with regions of interest in a B-scan. Fovea-centered OCT scans acquired with Spectralis (Heidelberg Engineering) were considered. A total of 3358 patients were used for development and testing. The detection performance was evaluated in a large data cohort with different pathologies including diabetic macular edema (DME) and the multiple stages of age-related macular degeneration (AMD) and on external public datasets with various disease biomarkers.</p><p><strong>Results: </strong>The volume-wise anomaly detection receiver operating characteristic (ROC) area under the curve (AUC) was 0.94 ± 0.05 in the test set. Pathological B-scan detection on external datasets varied between 0.81 and 0.87 AUC. Qualitatively, the derived anomaly maps pointed toward diagnostically relevant regions. The behavior of the system across the datasets was similar and consistent.</p><p><strong>Conclusions: </strong>Anomaly detection constitutes a valid complement to supervised systems aimed at improving the success of vision preservation and eye care, and is an important step toward more efficient and generalizable screening tools.</p><p><strong>Translational relevance: </strong>Deep learning approaches can enable an automated and objective screening of a wide range of pathological retinal conditions that deviate from normal appearance.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"26"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measurement of Aqueous Humor Viscosity in an Experimental Rabbit Model With Corneal Neovascularization.","authors":"Dong Eun Kim, Do Young Park, Jong Chul Han","doi":"10.1167/tvst.14.3.9","DOIUrl":"10.1167/tvst.14.3.9","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the relationship between aqueous humor (AH) viscosity and vascular endothelial growth factor-A (VEGF-A) in a corneal neovascularization (CNV) model.</p><p><strong>Methods: </strong>Ten female New Zealand rabbits were divided into two groups (n = 5 each). CNV was induced by alkaline burns on the right corneas of group B, whereas group A underwent a sham procedure. After 14 days, at least 150 µL of AH was extracted from both eyes. VEGF-A concentration was measured using ELISA, and AH viscosity was determined using a viscometer. Correlations between VEGF-A concentration, total protein concentration, and AH viscosity were assessed.</p><p><strong>Results: </strong>VEGF-A concentration was significantly elevated in CNV-induced eyes than in noninduced eyes (6029.06 ± 7116.50 pg/mL vs. 115.63 ± 33.19 pg/mL, P < 0.01). Total protein concentration was also elevated in CNV-induced eyes (11.66 ± 9.86 mg/mL) than in noninduced eyes (0.69 ± 0.06 mg/mL, P < 0.01), and correlated positively with VEGF-A (r = 0.84, P < 0.01). AH viscosity was significantly increased in CNV-induced eyes (1.82 ± 1.28 mPa-s) compared to noninduced eyes (1.05 ± 0.01 mPa-s, P < 0.01) and correlated strongly with VEGF-A concentration in CNV-induced eyes (r = 1.00, p = 0.02).</p><p><strong>Conclusions: </strong>AH viscosity positively correlated with VEGF-A concentration, particularly in CNV-induced eyes with elevated VEGF-A levels.</p><p><strong>Translational relevance: </strong>The correlation between VEGF-A levels and AH viscosity in an experimental model of corneal neovascularization suggests that AH viscosity could serve as a biomarker for predicting IOP or surgical outcomes in conditions like neovascular glaucoma.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"9"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the Performance of Stress-Strain Index Versions 1 and 2 in Normal and Keratoconus Patients.","authors":"Nan-Ji Lu, Marta Jiménez-García, Ahmed Elsheikh, Ahmed Makarem, Carina Koppen, Jos J Rozema","doi":"10.1167/tvst.14.3.23","DOIUrl":"10.1167/tvst.14.3.23","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to compare the performance of the Stress-Strain Index versions 1 and 2 (SSI and SSI2) in healthy patients and patients with keratoconus (KC).</p><p><strong>Methods: </strong>Fifty-two healthy and 104 KC eyes were examined using Scheimpflug-based tomography and air-puff tonometry (Pentacam and Corvis). Correlations between both versions of SSI and age, thinnest pachymetry, and tomographic parameters were assessed. To discriminate KC eyes from healthy eyes, receiver operating characteristic curves were generated to calculate the area under the curve (AUC) for both versions of SSI and compared with a Delong test.</p><p><strong>Results: </strong>Both versions of SSI showed statistical differences between the healthy group and the group of patients with KC (all P < 0.001). In the healthy group, significant correlations were found between both versions of SSI and age, K1, K2, and Kmax, between SSI and average relational thickness (ART) Max (R2 = 0.23) and between SSI2 and Belin A (R2 = 0.08). In the KC group, significant correlations were found between both versions of SSI and all tomographic parameters (all P < 0.01, except for SSI2 with age P = 0.346); the R2 values in SSI2 were consistently higher than in SSI. AUC for SSI and SSI2 when comparing normal and KC eyes was 0.772 and 0.740, respectively (P = 0.468).</p><p><strong>Conclusions: </strong>Both versions of SSI correlated with tomographic parameters describing KC severity, but correlations were higher for SSI2 and were not affected by age. Both versions demonstrated the same diagnostic ability for KC.</p><p><strong>Translational relevance: </strong>Both versions of SSI are not interchangeable, SSI2 may be preferred to depict the corneal stiffness.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"23"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal Microvascular Biomarker Assessment With Automated Algorithm and Semiautomated Software in the Montrachet Dataset.","authors":"Pétra Eid, Abderrahmane Bourredjem, Atif Anwer, Catherine Creuzot-Garcher, Pearse Andrew Keane, Yukun Zhou, Siegfried Wagner, Fabrice Meriaudeau, Louis Arnould","doi":"10.1167/tvst.14.3.13","DOIUrl":"10.1167/tvst.14.3.13","url":null,"abstract":"<p><strong>Purpose: </strong>To compare automated and semiautomated methods for the measurement of retinal microvascular biomarkers: the automated retinal vascular morphology (AutoMorph) algorithm and the Singapore \"I\" Vessel Assessment (SIVA) software.</p><p><strong>Methods: </strong>Analysis of retinal fundus photographs centered on optic discs from the population-based Montrachet Study of adults aged 75 years and older. Comparison and agreement evaluation with intraclass correlation coefficients (ICCs) between SIVA and AutoMorph measures of the central retinal venular and arteriolar equivalent, arteriolar-venular ratio, and fractal dimension.</p><p><strong>Results: </strong>Overall, 1069 fundus photographs were included in this study. The mean age of the patients was 80.04 ± 3.94 years. After the image quality grading process with an optimal threshold, the lowest rejection rate was 51.17% for the AutoMorph analysis (n = 522). The measure of agreement between SIVA and AutoMorph retinal microvascular biomarkers showed a good correlation for vascular complexity (ICC, 0.77-0.47), a poor correlation for vascular calibers (ICC, 0.36-0.23), and no correlation for vascular tortuosity. Significant associations between retinal biomarkers and systemic variables (age, history of stroke, and systolic blood pressure) were consistent between SIVA and AutoMorph.</p><p><strong>Conclusions: </strong>In this dataset, AutoMorph presented a substantial rejection rate. SIVA and AutoMorph provided well-correlated measurements of vascular complexity and caliber with consistent clinical associations. Further comparisons are needed before a transition is made from semiautomated to automated algorithms for the analysis of retinal microvascular biomarkers.</p><p><strong>Translational relevance: </strong>Open source software needs to be compared with former semiautomated software for retinal microvascular biomarkers assessment before transition in daily clinic and collaborative research.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"13"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual Deficits in Type 2 Diabetes Mellitus Without Retinopathy: From Retinal Structure to Higher-Level Visual Functions.","authors":"Sha Luo, Lin Xia, Yue Wang, Yong Tang, Jiong Dong, Rong Liu, Lixia Feng","doi":"10.1167/tvst.14.3.10","DOIUrl":"10.1167/tvst.14.3.10","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate deficits at varying levels of visual system in diabetes without clinical retinopathy (NoDR) and to explore the optimal method for detecting early diabetic visual disorders among functional and retinal structural assessments included.</p><p><strong>Methods: </strong>This cross-sectional study examined eyes by the Early Treatment of Diabetic Retinopathy Study (ETDRS) charts, visual psychophysical tests, optical coherence tomography (OCT), and OCT angiography (OCTA). Visual psychophysical metrics included grating acuity (GA), and contrast sensitivity to first-order motion stimuli (1stM), second-order contrast-modulated stationary stimuli (2ndS), and second-order motion stimuli (2ndM). Generalized linear mixed effect (GLME) models were applied to assess group effects and linear relationships between measurements. The receiver operating characteristic (ROC) analysis was utilized to identify the optimal classifier for detecting NoDR.</p><p><strong>Results: </strong>Fifty-three eyes of 33 patients with NoDR and 40 eyes of 27 healthy controls were included. The NoDR group showed significant reductions in various visual functions, including ETDRS acuity, GA, 2ndS, and 2ndM (P values < 0.001), and microvascular changes in foveal vascular density (FD-300), the acircularity index (AI) of the foveal avascular zone, and the parafoveal superficial capillary plexus density (P values < 0.05). GLME models revealed these retinal variations were not significantly correlated with early diabetic visual function abnormalities. ROC analysis demonstrated the integration of GA and FD-300 (area under the curve [AUC] = 0.911) is the most effective classifier for detecting early diabetic visual dysfunctions.</p><p><strong>Conclusions: </strong>In addition to retinal defects, both low- and higher-order visual function disorders along the visual pathway exist in patients with NoDR. Combining functional and structural measurements may provide more accurate assessments for detecting early diabetic visual disorders.</p><p><strong>Translational relevance: </strong>Sophisticated visual psychophysical measurements, including grating acuity and second-order function, could be applied for detecting early diabetic visual disorders.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"10"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Riboflavin Stromal Delivery Using Microchannel-Assisted Iontophoresis for Corneal Crosslinking.","authors":"Rohan Joshi, Samantha Bradford, Shangbang Luo, Emily Farrah, Yilu Xie, Donald J Brown, Tibor Juhasz, James V Jester","doi":"10.1167/tvst.14.3.18","DOIUrl":"10.1167/tvst.14.3.18","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to determine if iontophoresis of riboflavin (Rf) combined with femtosecond generated epithelial microchannels (MCs) could shorten the time required for Rf stromal delivery and subsequent crosslinking (CXL).</p><p><strong>Methods: </strong>Eighty-four ex vivo rabbit eyes were divided into three groups: group 1 = iontophoresis alone; group 2 = iontophoresis with MC; and group 3 = MC alone. Iontophoresis was performed using a small electric current with varying current and time. MCs were generated using a 1030 nm femtosecond (FS) laser to machine the corneal epithelial surface in a 6 mm diameter region. Ex vivo eyes were treated with topical iso-osmolar Rf solution, and stromal Rf concentration was determined spectrophotometrically by eluting Rf from trephined stromal buttons. In vivo, six rabbits underwent iontophoresis or iontophoresis + MC followed by ultraviolet-A crosslinking (UVA CXL) and imaged for collagen autofluorescence (CAF) signal to determine CXL efficacy.</p><p><strong>Results: </strong>Ex vivo iontophoresis achieved a threefold increase in stromal Rf concentration when combined with MC for 5 to 10 minutes (equivalent to MC alone for 30 minutes compared to iontophoresis alone). In vivo, iontophoresis + MC resulted in a significantly higher (4-fold) CAF intensity than iontophoresis alone.</p><p><strong>Conclusions: </strong>MCs and low current iontophoresis produce a significantly higher stromal Rf concentration than iontophoresis alone and equivalent to MC alone at greatly reduced Rf treatment time. Additionally, the combined treatment results in a four-fold increase in CAF intensity over iontophoresis alone.</p><p><strong>Translational relevance: </strong>A combined treatment of iontophoresis and MC significantly enhances stromal Rf concentration resulting in increased CXL while significantly reducing procedure time.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"18"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying the Progression of Stargardt Disease in Double-Null ABCA4 Carriers Using Fundus Autofluorescence Imaging.","authors":"Ivana Mihalek, Hanna De Bruyn, Tomislav Glavan, Annie M Lancos, Caitlin M Ciolfi, Katarzyna Malendowicz, Sigrid Aslaksen, Laurie L Molday, Robert S Molday, Anne B Fulton","doi":"10.1167/tvst.14.3.16","DOIUrl":"10.1167/tvst.14.3.16","url":null,"abstract":"<p><strong>Purpose: </strong>To score real-world fundus autofluorescence (FAF) images of pediatric patients with ABCA4-related Stargardt disease (STGD1), in a way that is automatable, scales with the disease progression, and is applicable to a wide time interval in the natural history of the disease.</p><p><strong>Methods: </strong>We developed the score based on a series of Optos wide-field FAF images of pediatric STGD1 patients (73 images; 14 individuals) and controls (27 images; 8 individuals). The patients' images were obtained over up to 6 years, and the controls over up to 5 years. In each image, we manually selected an artifact-free region, within which we evaluated an average of the pixel-level intensity score, constructed so that the average increases with progression of the disease.</p><p><strong>Results: </strong>The score we propose provides a statistically robust measure of disease progression (91% Spearman correlation with the absolute age, 97% with the estimated time from onset, when averaged over both eyes), comparable across timepoints and patients.</p><p><strong>Conclusions: </strong>FAF is a reliable tool in STGD1 diagnostics, but its quantitative description must be modified to be applicable to tracking the disease progression. Analyzing images obtained in the course of clinical care of pediatric patients poses special challenges that make complete automation difficult.</p><p><strong>Translational relevance: </strong>Our methodology provides a quantitative tool for investigating the natural progression of the Stargardt disease, and, potentially, the effects of genotype, environment, and therapeutic intervention on its course.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"16"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of 3D MRI and SS-OCT/OCTA in Assessment of Posterior Scleral Contraction for Myopic Traction Maculopathy.","authors":"Danyang Yu, Di Wu, Haoru Li, Hua Rong, Qing He, Xia Zhang, He Xu, Mengdi Chai, Yifan Zhou, Ruihua Wei","doi":"10.1167/tvst.14.3.5","DOIUrl":"10.1167/tvst.14.3.5","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the clinical efficacy and safety of posterior scleral contraction (PSC) in the treatment of myopic traction maculopathy (MTM) by three-dimensional magnetic resonance imaging (3D MRI), swept-source optical coherence tomography (SS-OCT) and swept-source optical coherence tomography angiography (SS-OCTA).</p><p><strong>Methods: </strong>In this prospective study, 30 eyes of 25 patients with MTM were treated with PSC. The ocular parameters of the patients were measured before surgery and at 1 month, 6 months, and 1 year after 3D MRI and SS-OCT/OCTA.</p><p><strong>Results: </strong>The differences in preoperative and postoperative parameters, including axial length (AL), spherical equivalent (SE), best-corrected visual acuity (BCVA), retinoschisis area, total posterior staphyloma height (PSH), and vitreous volume were statistically significant (P < 0.001). The choroidal thickness (CT) in each sector, choroidal perfusion area (CPA) in subfoveal and temporal sectors, and choroidal vascularity index (CVI) in inferior and temporal sectors increased significantly after PSC surgery (P < 0.05). Additionally, 3D MRI showed that the surgical strips remained strong and stable during the follow-up period, without complications such as strip displacement, fracture, and loosening.</p><p><strong>Conclusions: </strong>The application of 3D MRI and SS-OCT/OCTA in assessment of the treatment of MTM with PSC was comprehensive with multiple ocular parameters and could further guide the clinical diagnosis and treatment of MTM.</p><p><strong>Translational relevance: </strong>We combined SS-OCT/OCTA and 3D MRI to provide the basis of a theory for guiding the clinical diagnosis and treatment of MTM.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"5"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Performance, Low-Cost Optical Coherence Tomography System Using a Jetson Orin Nano for Real-Time Control and Image Processing.","authors":"Wan Wang, David A Miller, Hillel B Price, Xiangyue Yang, William J Brown, Adam Wax","doi":"10.1167/tvst.14.3.24","DOIUrl":"10.1167/tvst.14.3.24","url":null,"abstract":"<p><strong>Purpose: </strong>Optical coherence tomography (OCT) has become an indispensable tool for the detection and analysis of diseased retinal tissue. Recent advances in reducing the size and cost of OCT systems have aimed at expanding their use for new applications and settings, such as serving as a screening tool at the point of care or in low-resource areas. Here, we report on the development of a compact, low-cost OCT system that offers significantly improved performance while also further reducing cost and system size.</p><p><strong>Methods: </strong>A high-performance OCT system was realized by leveraging graphics processing unit (GPU)-accelerated parallel processing in a system on module, the NVIDIA Jetson Orin Nano, integrated into a low-cost OCT system. Instrument performance for retinal imaging was benchmarked against current low-cost OCT systems.</p><p><strong>Results: </strong>A fivefold increase in processing speed was obtained for the Jetson-powered low-cost OCT without loss of image quality. The compact and low-cost nature of the system was preserved while its volume was reduced by 67% and computing cost was reduced by 22%.</p><p><strong>Conclusions: </strong>The advance in imaging performance can significantly expand the accessibility and clinical utility of low-cost OCT systems.</p><p><strong>Translational relevance: </strong>Implementation of the system on module computer improved the computational performance without compromising the cost or size of low-cost OCT systems, which will accelerate the application of low-cost OCT to clinical use.</p>","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"24"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum in: Accelerometer-Measured Daily Behaviors That Mediate the Association Between Refractive Status and Depressive Disorders.","authors":"","doi":"10.1167/tvst.14.3.7","DOIUrl":"10.1167/tvst.14.3.7","url":null,"abstract":"","PeriodicalId":23322,"journal":{"name":"Translational Vision Science & Technology","volume":"14 3","pages":"7"},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}