The Peripheral Defocus Designed Spectacle Lenses Might Increase Astigmatism in Myopic Children.

IF 2.6 3区医学 Q2 OPHTHALMOLOGY

Translational Vision Science & Technology Pub Date : 2025-03-03 DOI:10.1167/tvst.14.3.8

Wenyan Xu, Xiaoman Li, Jianing Zhang, Hongyi Li, Xuewen Ding, Xiaoyue Hu, Xinyue Quan, Yue Su, Fan Lu, Jie Chen

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引用次数: 0

Abstract

Purpose: This study aims to explore the impact of wearing peripheral defocus spectacle lenses (PDSL) on cylindrical refractive error (CYL) in myopic children.

Methods: This study included 1057 myopic children and divided the participants into three groups: the HAL group (spectacle lens with highly aspherical lenslets), the MPV group (spectacle lens based on manipulating peripheral vision), and a control group (without myopia control interventions). The study analyzed the effect of wearing PDSL on changes in spherical equivalent refraction, CYL, and corneal astigmatism (CA). The mediating effect between changes in spherical refractive errors (SPH) and CYL was also investigated.

Results: Compared to the control group (0.05 ± 0.33 D), the annual CYL progression was faster in the HAL group (-0.15 ± 0.33 D, P < 0.001) and the MPV group (-0.09 ± 0.27 D, P = 0.019). More children in the HAL group had an annual CYL progression ≥0.50 D (HAL: 23.6%, Control: 16.2%, P = 0.012). The annual CYL and CA progression were consistent within the PDSL groups (HAL: P = 0.677, MPV: P = 0.683). The total effect of CYL progression in the HAL group was primarily due to direct induction from wearing HAL and indirect induction through the SPH control effect.

Conclusions: The application of PDSL could cause increase in astigmatism in myopic children, which could mainly be contributed to cornea astigmatism change.

Translational relevance: PDSL may passively affect the anterior ocular biomechanics during myopia control, leading to an increase in astigmatism.

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外周离焦设计的眼镜镜片可能增加近视儿童的散光。

目的：探讨配戴周边离焦镜片（PDSL）对近视儿童圆柱形屈光不正（CYL）的影响。方法：选取1057名近视儿童为研究对象，将其分为三组：HAL组（高度非球面眼镜）、MPV组（基于操纵周边视觉的眼镜）和对照组（不进行近视控制干预）。本研究分析了佩戴PDSL对球面等效折射、CYL和角膜散光（CA）变化的影响。研究了球面屈光差（SPH）变化与CYL之间的中介作用。结果：与对照组（0.05±0.33 D）相比，HAL组（-0.15±0.33 D, P < 0.001）和MPV组（-0.09±0.27 D, P = 0.019）的CYL年进展更快。HAL组CYL年进展≥0.50 D的患儿较多（HAL组：23.6%，Control组：16.2%,P = 0.012）。在PDSL组中，CYL和CA的年度进展一致（HAL: P = 0.677, MPV: P = 0.683）。HAL组CYL进展的总效应主要是由于佩戴HAL直接诱导和通过SPH控制效应间接诱导。结论：PDSL的应用可引起近视儿童散光的增加，其主要原因可能是角膜散光的改变。翻译相关性：PDSL可能在近视控制过程中被动影响眼前生物力学，导致散光增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Translational Vision Science & Technology Engineering-Biomedical Engineering

CiteScore

5.70

自引率

3.30%

发文量

346

审稿时长

25 weeks

期刊介绍： Translational Vision Science & Technology (TVST), an official journal of the Association for Research in Vision and Ophthalmology (ARVO), an international organization whose purpose is to advance research worldwide into understanding the visual system and preventing, treating and curing its disorders, is an online, open access, peer-reviewed journal emphasizing multidisciplinary research that bridges the gap between basic research and clinical care. A highly qualified and diverse group of Associate Editors and Editorial Board Members is led by Editor-in-Chief Marco Zarbin, MD, PhD, FARVO. The journal covers a broad spectrum of work, including but not limited to: Applications of stem cell technology for regenerative medicine, Development of new animal models of human diseases, Tissue bioengineering, Chemical engineering to improve virus-based gene delivery, Nanotechnology for drug delivery, Design and synthesis of artificial extracellular matrices, Development of a true microsurgical operating environment, Refining data analysis algorithms to improve in vivo imaging technology, Results of Phase 1 clinical trials, Reverse translational ("bedside to bench") research. TVST seeks manuscripts from scientists and clinicians with diverse backgrounds ranging from basic chemistry to ophthalmic surgery that will advance or change the way we understand and/or treat vision-threatening diseases. TVST encourages the use of color, multimedia, hyperlinks, program code and other digital enhancements.