Toxics最新文献 - Book学术

Assessment of the Physicochemical Properties of Ultrafine Particles (UFP) from Vehicular Emissions in a Commercial Parking Garage: Potential Health Implications. 评估商业停车场车辆排放的超细粒子 (UFP) 的物理化学特性：潜在的健康影响。

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-20 DOI: 10.3390/toxics12110833

Nachiket Vaze, Leonardo Calderon, Irini Tsiodra, Nikolaos Mihalopoulos, Charles N Serhan, Bruce D Levy, Philip Demokritou

{"title":"Assessment of the Physicochemical Properties of Ultrafine Particles (UFP) from Vehicular Emissions in a Commercial Parking Garage: Potential Health Implications.","authors":"Nachiket Vaze, Leonardo Calderon, Irini Tsiodra, Nikolaos Mihalopoulos, Charles N Serhan, Bruce D Levy, Philip Demokritou","doi":"10.3390/toxics12110833","DOIUrl":"10.3390/toxics12110833","url":null,"abstract":"Vehicular emissions are a major culprit in the rise of urban air pollution. The particulate matter (PM) emitted from vehicular sources includes primarily ultrafine particles (UFPs) with aerodynamic diameters less than 0.1 µm (PM0.1) and is linked to adverse respiratory and cardiovascular health effects. Despite this knowledge, few exposure assessment studies exist that detail the physicochemical properties of PM in parking garages. In this study, airborne PM emitted by vehicles in a parking garage of a hospital in New Jersey was sampled, during winter and summer seasons, and physicochemically characterized. The results indicate that the mass concentrations of the UFPs in the garage were 2.51 µg/m3 and 3.59 µg/m3, respectively. These UFPs contained a large percentage of elemental carbon and toxic elements. They also contained polycyclic aromatic hydrocarbons (PAHs), having deleterious health effects. An inhalation particle modeling revealed that 23.61% of these UFPs are deposited in the pulmonary region of the lung, translating to a dose of 10.67 µg for winter and 15.25 µg for summer, over a typical 40 h work week. These high deposited levels of UFPs and their complex chemistry levels further warrant the need for toxicological assessment of UFPs related to vehicular emissions.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11597990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rodlet Cell Morpho-Numerical Alterations as Key Biomarkers of Fish Responses to Toxicants and Environmental Stressors. 作为鱼类对有毒物质和环境胁迫反应的关键生物标志物的杆状细胞形态-数量变化

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-20 DOI: 10.3390/toxics12110832

Maurizio Manera

{"title":"Rodlet Cell Morpho-Numerical Alterations as Key Biomarkers of Fish Responses to Toxicants and Environmental Stressors.","authors":"Maurizio Manera","doi":"10.3390/toxics12110832","DOIUrl":"10.3390/toxics12110832","url":null,"abstract":"Rodlet cells (RCs) are specialised immune cells found in teleost fish, recognised for their unique morphology and potential roles in both immune responses and environmental adaptation. Herein, current knowledge on RCs is reviewed, focussing on their responsiveness to toxicants and environmental stressors. The historical context of RC research is discussed, including key milestones in the identification and characterisation of these cells. Recent studies highlight RCs' quantitative and qualitative changes in response to various pollutants, such as heavy metals, organic chemicals, and microplastics, underscoring their utility as biomarkers for environmental monitoring and assessment of ecological health. The underlying mechanisms that govern RC responses are explored, noting the limited research available at the molecular level, which hampers a comprehensive understanding of their functionality. Despite this, the consistent patterns of RC responses position them as valuable indicators of environmental health within the One Health framework, linking aquatic ecosystem integrity to broader human and animal health concerns. Additionally, the potential equivalence of RCs in other vertebrates is examined, which may provide insights into their evolutionary significance and functional roles across different species. The urgent need for further research is emphasised to enhance the understanding of RC biology and its applications in toxicology and environmental pathology.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11598299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Metal Tolerance Proteins (MTPs) Associated with the Homeostasis of Divalent Mineral Elements in Ga-Treated Rice Plants. 经 Ga 处理的水稻植株中与二价矿质元素平衡相关的金属耐受性蛋白 (MTP) 的作用

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-20 DOI: 10.3390/toxics12110831

Hao Zhan, Cheng-Zhi Li, Yi Kang, Xiao-Zhang Yu

{"title":"The Role of Metal Tolerance Proteins (MTPs) Associated with the Homeostasis of Divalent Mineral Elements in Ga-Treated Rice Plants.","authors":"Hao Zhan, Cheng-Zhi Li, Yi Kang, Xiao-Zhang Yu","doi":"10.3390/toxics12110831","DOIUrl":"10.3390/toxics12110831","url":null,"abstract":"Mineral elements typically act as transported substrates for metal tolerance proteins (MTPs). The chelation of MTPs with heavy metal ions is a suggestive detoxification pathway in plants; therefore, the trade-off between transporting mineral elements and chelating excess toxic metal ions is inevitable. Gallium (Ga) is an emerging pollutant associated with high-tech industries. This study investigated the impact of Ga stress on MTPs, subsequently altering the transport and distribution of mineral elements. Gallium exposure reduced rice seedling biomass, with roots accumulating more Ga than shoots. Ga stress also changed the rice plants' subcellular mineral element distribution. PCR assays showed that Ga stress negatively affected all genes belonging to the Mn group, except OsMTP9. While Mn accumulation in the rice cellular compartments did not respond positively to Ga stress, OsMTP8, OsMTP8.1, OsMTP11, and OsMTP11.1 were found to be intimately connected to Mn transport and repressed by increased Ga accumulation in roots. Mg and Cu accumulated in the cytosol and organelles of Ga-treated rice plants, while OsMTP9 expression increased, demonstrating its importance in transporting Mg and Cu. A positive link between Ga stress and Zn accumulation in the cytosol and organelles was found, and OsMTP7 and OsMTP12 expression was positive, suggesting that Ga stress did not impair their Zn transport. Notably, Ga exposure down-regulated Fe-transporting OsMTP1 and OsMTP6, wherein the subcellular concentrations of Fe showed negative responses to Ga accumulation. These findings provide valuable insights into elucidating the roles of OsMTPs in Ga tolerance and the transport of these mineral elements.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11598383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gender-Specific Toxic Effects of S-Metolachlor and Its Metabolite on Hibernating Lizards: Implications for Reproductive Health and Ecosystem Vulnerability. S-甲草胺及其代谢物对冬眠蜥蜴的性别特异性毒性效应：对生殖健康和生态系统脆弱性的影响。

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-20 DOI: 10.3390/toxics12110834

Li Chen, Jinling Diao, Zhongnan Tian, Dezhen Wang, Wenjun Zhang, Luyao Zhang, Zikang Wang, Zhiqiang Zhou, Shanshan Di

{"title":"Gender-Specific Toxic Effects of S-Metolachlor and Its Metabolite on Hibernating Lizards: Implications for Reproductive Health and Ecosystem Vulnerability.","authors":"Li Chen, Jinling Diao, Zhongnan Tian, Dezhen Wang, Wenjun Zhang, Luyao Zhang, Zikang Wang, Zhiqiang Zhou, Shanshan Di","doi":"10.3390/toxics12110834","DOIUrl":"10.3390/toxics12110834","url":null,"abstract":"Reptiles rely on hibernation to survive harsh winters, but climate change and pesticide use in agriculture jeopardize their survival, making the ecosystem vulnerable. S-metolachlor (SM), a commonly found herbicide in soil, and its metabolite metolachlor oxanilic acid (MO) induce oxidative stress and disrupt reproductive hormones. In this study, lizards were exposed to SM- and MO-contaminated soil for 45 days during hibernation. Weight loss and deaths occurred at the beginning of hibernation in all groups. Furthermore, the exposure group experienced severe oxidative stress and damage in the liver, kidney, heart, gonad, and brain. The testosterone levels significantly decreased in male lizards in both the SM and MO groups, whereas estradiol levels increased significantly in female lizards in the SM group. Gender-specific expression of steroidogenic-related genes in the brains and gonads of lizards was observed. Histological analysis revealed toxic effects induced by both SM and MO in vital organs during hibernation. Moreover, MO induced more severe reproductive toxicity in male lizards during hibernation. Therefore, this study suggests gender-specific toxic effects were observed in hibernating lizards exposed to SM and MO, underscoring the importance of vigilant monitoring of pesticide application in agriculture and assessing the potential harm of its metabolites.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11598707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Environmental Hazards and Treatment of Ship's Domestic Sewage. 船舶生活污水的环境危害和处理。

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-19 DOI: 10.3390/toxics12110826

Yanan Zhang, Bensen Xian, Wenkai Sun, Ruifang Lu, Qin Zhang, Mei Wang, Dandan Xu, Huili Liu, Shaoyuan Bai, Mingming Fu

{"title":"The Environmental Hazards and Treatment of Ship's Domestic Sewage.","authors":"Yanan Zhang, Bensen Xian, Wenkai Sun, Ruifang Lu, Qin Zhang, Mei Wang, Dandan Xu, Huili Liu, Shaoyuan Bai, Mingming Fu","doi":"10.3390/toxics12110826","DOIUrl":"10.3390/toxics12110826","url":null,"abstract":"With the rapid development of the modern shipping field, the damage caused by ship pollution to the global inland waterways and marine ecosystems has attracted extensive attention from the international community. However, there are fewer reviews on the environmental hazards of domestic ship sewage and its treatment, and a systematic summary of the environmental hazards posed by ship domestic sewage and its treatment is lacking. Based on summarizing the various environmental hazards brought about by a ship's domestic sewage and the corresponding treatment methods, this study elaborates, in detail, on the specific hazards of the main toxic and hazardous substances contained in a ship's domestic sewage on the environment and organisms, and the treatment methods of the ship's domestic sewage and their treatment effects, such as membrane bioreactor (MBR). It is also pointed out that MBR has great potential in the direction of ship domestic sewage treatment, and the solution of its membrane pollution and other problems as well as the exploration of the combination of MBR and other treatment methods will become the focus of future research. A theoretical reference is provided for the study of environmental problems caused by domestic sewage from ships and their treatment options.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11598621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exposure to Per- and Polyfluoroalkyl Substances and Risk of Psoriasis: A Population-Based Study. 接触全氟和多氟烷基物质与牛皮癣风险：一项基于人群的研究。

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-19 DOI: 10.3390/toxics12110828

Qing Zhang, Mengyue Zhang, Cunxi Zhao

{"title":"Exposure to Per- and Polyfluoroalkyl Substances and Risk of Psoriasis: A Population-Based Study.","authors":"Qing Zhang, Mengyue Zhang, Cunxi Zhao","doi":"10.3390/toxics12110828","DOIUrl":"10.3390/toxics12110828","url":null,"abstract":"PFAS are a group of synthetic chemicals that have been reported to be associated with adverse health outcomes. However, the relationship of PFAS exposure with psoriasis risk has not been reported. Utilizing data from the 2003-2018 NHANES, we explored the relationship of PFAS exposure with psoriasis risk. Our study included 5370 participants and examined serum levels of five PFAS compounds: PFOA, PFOS, PFHxS, PFNA, and PFDA, along with self-reported psoriasis status. Generalized linear regression, quantile g-computation, repeated hold out WQS regression, and BKMR models were employed to assess individual and combined effects of PFAS on psoriasis risk. We found each doubling the PFOS concentration was associated with a 19% increased risk of psoriasis (OR: 1.19; 95% CI: 1.01, 1.41) in the overall population. Sex-stratified analyses indicated significant associations between PFOA and PFNA exposure and psoriasis risk in females. Mixture analyses using WQS regression indicated that PFAS mixtures were associated with an 11% increased risk of psoriasis (OR: 1.11, 95% CI: 1.01, 1.22) in females in both the negative and positive direction. BKMR analyses also indicated a positive trend of PFAS mixtures with psoriasis risk in females. Our findings indicate a possible association between PFAS exposure and psoriasis risk, particularly in females.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11598214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lead Concentrations in Tissues of Pigeons (Columba livia) in the Urban Area of Comarca Lagunera, Mexico. 墨西哥 Comarca Lagunera 城市地区鸽子（Columba livia）组织中的铅含量。

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-19 DOI: 10.3390/toxics12110830

Andrea Ocampo-Lopez, Cristo Omar Puente-Valenzuela, Homero Sánchez-Galván, Ana Alejandra Valenzuela-García, Josué Raymundo Estrada-Arellano, Ramón Alfredo Delgado-González, Jorge Alejandro Aguirre-Joya, Cristian Torres-León, Alejandra Ocampo-Lopez, David Ramiro Aguillón-Gutiérrez

{"title":"Lead Concentrations in Tissues of Pigeons (Columba livia) in the Urban Area of Comarca Lagunera, Mexico.","authors":"Andrea Ocampo-Lopez, Cristo Omar Puente-Valenzuela, Homero Sánchez-Galván, Ana Alejandra Valenzuela-García, Josué Raymundo Estrada-Arellano, Ramón Alfredo Delgado-González, Jorge Alejandro Aguirre-Joya, Cristian Torres-León, Alejandra Ocampo-Lopez, David Ramiro Aguillón-Gutiérrez","doi":"10.3390/toxics12110830","DOIUrl":"10.3390/toxics12110830","url":null,"abstract":"The Comarca Lagunera is one of Mexico's most important productive areas. Its main economic activities are livestock, agriculture, and the processing industry. A wide variety of industries emit wastes that are considered highly toxic environmental pollutants, which have strong negative impacts on public health. The objective of this work was to determine the lead concentrations present in tissues of pigeons (Columba livia) belonging to the urban area of the Comarca Lagunera, Mexico. Specimens were collected from the localities that comprise the region and the tissue extracted; the organs were dried, calcined, and diluted in an acidic HCl solution. Lead concentrations were obtained by atomic absorption spectrometry using the graphite furnace technique. The results demonstrate the presence of lead in all the tissues analyzed, with maximum concentrations of 191.14 mg/kg and minimum concentrations of 0.86 mg/kg, the area with the highest average concentration being Torreón, Coahuila (p = 0.030). The organ with the highest concentration was the bone (p = 0.000). Evidence of lead poisoning is presented in Columba livia tissues in the Comarca Lagunera, thus demonstrating the presence of this contaminant and the ability of these pigeons to function as bioindicators of environmental contamination.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11598659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Exposure Status of Environmental Chemicals in South Korea: The Korean National Environmental Health Survey 2018-2020. 韩国环境化学品暴露状况：韩国全国环境健康调查 2018-2020》。

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-19 DOI: 10.3390/toxics12110829

Sooyeon Hong, Ok-Jin Kim, Sun Kyoung Jung, Hye Li Jeon, Suejin Kim, Jihyon Kil

{"title":"The Exposure Status of Environmental Chemicals in South Korea: The Korean National Environmental Health Survey 2018-2020.","authors":"Sooyeon Hong, Ok-Jin Kim, Sun Kyoung Jung, Hye Li Jeon, Suejin Kim, Jihyon Kil","doi":"10.3390/toxics12110829","DOIUrl":"10.3390/toxics12110829","url":null,"abstract":"In South Korea, a Human Biomonitoring (HBM) program, known as the Korean National Environmental Health Survey (KoNEHS), was launched in 2009. This study aims to provide an overview of environmental chemical exposures in South Korea based on data from the KoNEHS cycle 4 (2018-2020). To ensure population representativeness, Koreans aged 3 years and older were recruited from 426 sites across the country. A total of 6381 participants joined in the collection of biospecimens, which were subsequently analyzed for 33 environmental chemicals or their metabolites, including nine that were not included in the previous cycle. The five most common PFASs were detected in more than 99.7% of the participants. The GM of serum PFOS was the highest in adults at 15.1 µg/L (13.9, 16.4) and in adolescents at 7.97 µg/L (7.42, 8.56). In adults, there was a gradual decrease in the detection rate and concentration of some heavy metals and phthalate metabolites. In children and adolescents, the detection rate of BPA in urine decreased, while the rate of its substitutes BPF and BPS increased, and the rate of propyl paraben in urine decreased significantly. The results of the KoNEHS cycle 4 indicate that exposure levels to certain environmental chemicals are still high, highlighting further monitoring and on-going surveys to determine their trends, especially for newly investigated substances, such as PFASs.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11597996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Towards Cleaner Cities: Estimating Vehicle-Induced PM_2.5 with Hybrid EBM-CMA-ES Modeling. 迈向更清洁的城市：利用 EBM-CMA-ES 混合建模估算车辆引起的 PM2.5。

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-19 DOI: 10.3390/toxics12110827

Saleh Alotaibi, Hamad Almujibah, Khalaf Alla Adam Mohamed, Adil A M Elhassan, Badr T Alsulami, Abdullah Alsaluli, Afaq Khattak

{"title":"Towards Cleaner Cities: Estimating Vehicle-Induced PM2.5 with Hybrid EBM-CMA-ES Modeling.","authors":"Saleh Alotaibi, Hamad Almujibah, Khalaf Alla Adam Mohamed, Adil A M Elhassan, Badr T Alsulami, Abdullah Alsaluli, Afaq Khattak","doi":"10.3390/toxics12110827","DOIUrl":"10.3390/toxics12110827","url":null,"abstract":"In developing countries, vehicle emissions are a major source of atmospheric pollution, worsened by aging vehicle fleets and less stringent emissions regulations. This results in elevated levels of particulate matter, contributing to the degradation of urban air quality and increasing concerns over the broader effects of atmospheric emissions on human health. This study proposes a Hybrid Explainable Boosting Machine (EBM) framework, optimized using the Covariance Matrix Adaptation Evolution Strategy (CMA-ES), to predict vehicle-related PM2.5 concentrations and analyze contributing factors. Air quality data were collected from Open-Seneca sensors installed along the Nairobi Expressway, alongside meteorological and traffic data. The CMA-ES-tuned EBM model achieved a Mean Absolute Error (MAE) of 2.033 and an R2 of 0.843, outperforming other models. A key strength of the EBM is its interpretability, revealing that the location was the most critical factor influencing PM2.5 concentrations, followed by humidity and temperature. Elevated PM2.5 levels were observed near the Westlands roundabout, and medium to high humidity correlated with higher PM2.5 levels. Furthermore, the interaction between humidity and traffic volume played a significant role in determining PM2.5 concentrations. By combining CMA-ES for hyperparameter optimization and EBM for prediction and interpretation, this study provides both high predictive accuracy and valuable insights into the environmental drivers of urban air pollution, providing practical guidance for air quality management.","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"12 11","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11598042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Wang et al. Multi-Walled Carbon Nanotubes Accelerate Leukaemia Development in a Mouse Model. Toxics 2024, 12, 646. 更正：多壁碳纳米管在小鼠模型中加速白血病的发展。毒物 2024，12，646。

IF 3.9 3区环境科学与生态学

Toxics Pub Date : 2024-11-18 DOI: 10.3390/toxics12110823

Qingqing Wang, Jingdan Han, Mujia Wei, Huikai Miao, Min Zhang, Biao Wu, Yao Chen, Yanwen Zheng, Robert Peter Gale, Bin Yin

引用次数: 0