Toxics最新文献

{"title":"The Hidden Legacy of Dimethoate: Clay Binding Effects on Decreasing Long-Term Retention and Reducing Environmental Stability in Croatian Soils.","authors":"Romano Karleuša, Jelena Marinić, Dijana Tomić Linšak, Igor Dubrović, Domagoj Antunović, Dalibor Broznić","doi":"10.3390/toxics13030219","DOIUrl":"10.3390/toxics13030219","url":null,"abstract":"<p><p>Understanding the dynamics of sorption and desorption is essential for assessing the persistence and mobility of pesticides. These processes continue to influence ecological outcomes even after pesticide use has ended, as demonstrated by our study on dimethoate behavior in distinct soil samples from Croatia, including coastal, lowland, and mountainous regions. This study focuses on the sorption/desorption behavior of dimethoate in soil, explores the relationship between its molecular structure and the properties of soil organic and inorganic matter, and evaluates the mechanisms of the sorption/desorption process. The behavior of dimethoate was analyzed using a batch method, and the results were modeled using nonlinear equilibrium models: Freundlich, Langmuir, and Temkin models. Soils with a higher organic matter content, especially total organic carbon (TOC), showed a better sorption capacity compared to soils with a lower TOC. This is probably due to the less flexible structures in the glassy phase, which, unlike the rubbery phase in high TOC soils, do not allow dynamic and flexible binding of dimethoate within the organic matter. The differences between the H/C and O/C ratios indicate that in high TOC soils, flexible aliphatic compounds, typical of a rubbery phase, retain dimethoate more effectively, whereas a higher content of oxygen-containing functional groups in low TOC soils provides strong association. The lettered soils showed stronger retention of dimethoate through interactions with clay minerals and metal cations such as Mg²⁺, suggesting that clay plays a significantly more important role in enhancing dimethoate sorption than organic matter. These results highlight the importance of organic matter, clay, and metal ions in the retention of dimethoate in soil, indicating the need for remediation methods for those pesticides that, although banned, have had a long history of use.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11945934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atmospheric Heavy Metal Pollution Characteristics and Health Risk Assessment Across Various Type of Cities in China.","authors":"Zhichun Cha, Xi Zhang, Kai Zhang, Guanhua Zhou, Jian Gao, Sichu Sun, Yuanguan Gao, Haiyan Liu","doi":"10.3390/toxics13030220","DOIUrl":"10.3390/toxics13030220","url":null,"abstract":"<p><p>This study investigates the spatiotemporal trends and health risks of nine atmospheric heavy metals (Pb, As, Mn, Ni, Cr, Cd, Zn, Cu, Fe) in PM_2.5 across 50 Chinse cities, comparing resource-industrial cities (RICs) and general cities (GCs) before (2014-2018) and after (2019-2021) China's 2018 Air Pollution Prevention and Control Action Plan. Post-2018, concentrations of all metals except Fe declined significantly (33-77%), surpassing PM_2.5 reductions (25%). Geospatial analysis revealed elevated heavy metal levels in northern and southern regions in China, aligning with industrial and mining hotspots. While RICs exhibited persistently higher metal concentrations than GCs, the inter-city gap narrowed post-2018, with RICs achieving greater reduction. Pre-2018, the combined non-carcinogenic hazard index (HI < 1) remained below safety thresholds, but the combined carcinogenic risk total (CRT) for children exceeded 10^-4, driven primarily by As and Cr(VI). HIs were 1.5-2.0 times higher in RICs than in GCs. Post-2018, the CRT declined by 69.0-71.1%, aligning with reduced heavy metal levels. Despite improvements, CRTs necessitate targeted mitigation for As (contributing 81.1-86.2% to CRT) and Cr(VI) (11.7-14.0%). These findings validate the policy's effectiveness in curbing industrial and vehicular emissions but underscore the need for metal-specific controls in resource-intensive regions to safeguard child health.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11945492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of a Nanoscale Iron-Chlorobenzene Mixture on Pulmonary Injury in Rat Pups: Extending Exposure Knowledge Using Network Technology.","authors":"Kezhou Liu, Ying Xu, Mengjie Ying, Meiling Chen","doi":"10.3390/toxics13030221","DOIUrl":"10.3390/toxics13030221","url":null,"abstract":"<p><p>Particulate matter coexists with persistent organic pollutants (POPs) in the atmosphere, which can enter the human body by accompanying inhalable particles in the respiratory tract. Photochemical conversion further alters the chemical composition of the precursor particles and secondary products. This study investigated the effects of nanoscale iron-chlorobenzene mixtures and their photochemical conversion products on early lung development in rat pups. Using network toxicology and animal experiments, we constructed a compound toxicity-target network and developed air exposure models. This study revealed that both pollutants, before and after photochemical conversion, bound to the aryl hydrocarbon receptor (AhR), increased oxidative stress, altered lung tissue morphology, and reduce inflammatory factor expression. Rat pups were highly sensitive to pollutants during critical stages of lung development. However, no significant differences in oxidative stress or inflammation were observed between the pollutants, likely because of immature lung tissues. Once tissue damage reached a threshold, the response to increasing pollutant concentrations diminished. This study provides insights into atmospheric pollutant toxicity and scientific evidence for the risk assessment of dioxin-like nanoscale mixtures.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11946418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Impact of Aviation Emissions on Air Quality at a Regional Greek Airport Using Machine Learning.","authors":"Christos Stefanis, Ioannis Manisalidis, Elisavet Stavropoulou, Agathangelos Stavropoulos, Christina Tsigalou, Chrysoula Chrysa Voidarou, Theodoros C Constantinidis, Eugenia Bezirtzoglou","doi":"10.3390/toxics13030217","DOIUrl":"10.3390/toxics13030217","url":null,"abstract":"<p><p>Aviation emissions significantly impact air quality, contributing to environmental degradation and public health risks. This study aims to assess the impact of aviation-related emissions on air quality at Alexandroupolis Regional Airport, Greece, and evaluate the role of meteorological factors in pollution dispersion. Using machine learning models, we analyzed emissions data, including CO₂, NOx, CO, HC, SOx, PM_2.5, fuel consumption, and meteorological parameters from 2019-2020. Results indicate that NOx and CO₂ emissions showed the highest correlation with air traffic volume and fuel consumption (R = 0.63 and 0.67, respectively). Bayesian Linear Regression and Linear Regression emerged as the most accurate models, achieving an R² value of 0.96 and 0.97, respectively, for predicting PM_2.5 concentrations. Meteorological factors had a moderate influence, with precipitation negatively correlated with PM_2.5 (-0.03), while temperature and wind speed showed limited effects on emissions. A significant decline in aviation emissions was observed in 2020, with CO₂ emissions decreasing by 28.1%, NOx by 26.5%, and PM_2.5 by 35.4% compared to 2019, reflecting the impact of COVID-19 travel restrictions. Carbon dioxide had the most extensive percentage distribution, accounting for 75.5% of total emissions, followed by fuels, which accounted for 24%, and the remaining pollutants, such as NOx, CO, HC, SOx, and PM_2.5, had more minor impacts. These findings highlight the need for optimized air quality management at regional airports, integrating machine learning for predictive monitoring and supporting policy interventions to mitigate aviation-related pollution.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11945904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arsenic Exposure During Pregnancy and Childhood: Factors Explaining Changes over a Decade.","authors":"Paola Rubilar, Macarena Hirmas-Adauy, Mauricio Apablaza, Camila Awad, Xaviera Molina, María Pía Muñoz, Iris Delgado, Nicolás C Zanetta-Colombo, Carla Castillo-Laborde, María Isabel Matute, Mauricio A Retamal, Andrea Olea, Paulina Pino, Claudia González, Cristóbal Carvajal, Verónica Iglesias","doi":"10.3390/toxics13030215","DOIUrl":"10.3390/toxics13030215","url":null,"abstract":"<p><p>Arsenic chronic exposure, particularly in its inorganic form, represents a significant public health concern. This study was conducted in Arica, the northernmost city in the country, whose inhabitants have been exposed to inorganic arsenic both naturally through drinking water and anthropogenically due to a toxic waste disposal site. We explored changes in inorganic arsenic levels in a cohort of pregnant women and their children over a decade, identifying exposure trends and their determinants. We used data on arsenic exposure through maternal urine samples during pregnancy, collected by the Health Authority between 2013 and 2016 (measurement 1), and followed up with assessments of their children in 2023 (measurement 2). Temporal changes in inorganic arsenic concentration were analyzed using the Wilcoxon Signed-Rank test, and a mixed linear regression model was employed to determine which factors contributed to urinary inorganic arsenic levels. We did not observe significant differences in mean arsenic concentrations between the two-time points (<i>p</i> = 0.4026). The mixed linear regression model revealed that children consuming bottled water had 8.3% lower urinary inorganic arsenic concentrations than those drinking tap water (95% CI: -15.36 to -0.54%). Additionally, children from ethnic groups had 8.64% higher inorganic arsenic concentrations (95% CI: 0.49 to 17.5%), while those with caregivers with higher education showed a 13.67% reduction (95% CI: -25.06 to -0.56%). Despite mitigation efforts, these findings underscore the ongoing risk of inorganic arsenic exposure among vulnerable populations. They further emphasize the importance of addressing natural arsenic contamination in water and implementing targeted interventions to reduce disparities associated with socioeconomic and demographic factors.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11945348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomonitoring-Based Risk Assessment of Pyrethroid Exposure in the U.S. Population: Application of High-Throughput and Physiologically Based Kinetic Models.","authors":"Nan-Hung Hsieh, Eric S C Kwok","doi":"10.3390/toxics13030216","DOIUrl":"10.3390/toxics13030216","url":null,"abstract":"<p><p>Pyrethroid insecticides have been extensively utilized in agriculture and residential areas in the United States. This study evaluated the exposure risk by age using available biomonitoring data. We analyzed pyrethroid metabolite concentrations in urine using the National Health and Nutrition Examination Survey (NHANES) data. Reverse dosimetry was conducted with a high-throughput model and a physiologically based kinetic (PBK) model integrated with a Bayesian inference framework. We further derived Benchmark Dose (BMD) values and systemic points of departure in rats using Bayesian BMD and PBK models. Margins of exposure (MOE) were calculated to assess neurotoxic risk based on estimated daily oral intake and dose metrics in plasma and brain. Results from both models indicated that young children have higher pyrethroid exposure compared to other age groups. All estimated risk values were within acceptable levels of acute neurotoxic effect. Additionally, MOEs calculated from oral doses were lower than those derived from internal doses, highlighting that traditional external exposure assessments tend to overestimate risk compared to advanced internal dose-based techniques. In conclusion, combining high-throughput and PBK approaches enhances the understanding of human health risks associated with pyrethroid exposures, demonstrating their potential for future applications in exposure tracking and health risk assessment.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11945574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety Profile and Hepatotoxicity of Anaplastic Lymphoma Kinase Tyrosine Kinase Inhibitors: A Disproportionality Analysis Based on FDA Adverse Event Reporting System Database.","authors":"Yun Yang, Shiyi Tan, Yuepu Pu, Juan Zhang","doi":"10.3390/toxics13030210","DOIUrl":"10.3390/toxics13030210","url":null,"abstract":"<p><p>Anaplastic lymphoma kinase tyrosine kinase inhibitors (ALK-TKIs) have become first-line therapies for advanced non-small cell lung cancer (NSCLC) with ALK rearrangements. This study investigates ALK-TKI-associated adverse events (AEs), focusing on identifying hepatotoxicity signals and previously undocumented safety concerns. Using disproportionality analysis of 56,864 reports from the FDA Adverse Event Reporting System (FAERS) database, we systematically classified AEs via the Medical Dictionary for Regulatory Activities (MedDRA). At the System Organ Class (SOC) level, crizotinib exhibited a significantly stronger signal for eye disorders, ceritinib was uniquely linked to gastrointestinal disorders, and loratinib was predominantly associated with metabolism and nutrition disorders. Several AEs previously undocumented in drug labels were identified, including pericardial effusion, elevated C-reactive protein, hemolytic anemia, hemoptysis, and decreased hemoglobin. Furthermore, crizotinib, ceritinib, and alectinib were significantly associated with hepatotoxicity, marked by elevated alanine aminotransferase, aspartate aminotransferase, and hepatic enzyme levels. These findings highlight the need for vigilant monitoring of unlabeled AEs and potential label updates, particularly for hepatotoxicity risks associated with crizotinib, ceritinib, and alectinib.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11946249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of Illuminance and Color-Temperature Conditions for Railway Passengers' Comfort Based on Oxygenated Hemoglobin Saturation in the Brain.","authors":"Minkyeong Kim, Jooyeon Lee, Yonghee Lee, Duckshin Park","doi":"10.3390/toxics13030212","DOIUrl":"10.3390/toxics13030212","url":null,"abstract":"<p><p>Railway travel is an eco-friendly means of transportation, and passengers are spending increasing amounts of time on trains while engaging in various activities. As a major factor affecting railway passengers' comfort, we investigated the effects of lighting. Korean train cars are required to have two rows of light-emitting diode lights with a minimum illuminance of 500 lx, so we examined changes in cerebral blood flow under various illuminance conditions around this threshold value. We used functional near-infrared spectroscopy to measure prefrontal cortex activation in 29 college students under illuminance values of 300, 500, and 800 lx and color-temperature values of 2700 K (bulb color), 4000 K (white color), and 5500 K (blue color). Mean brain activity values were compared using analysis of variance. Of the 48 channels, significant interaction effects between color and illuminance on brain activation responses were observed for channel 38, as well as in the right dorsolateral prefrontal cortex among the different brain regions of the Brodmann area (<i>p</i> < 0.05). Oxygenated hemoglobin concentrations had consistently negative values for all the treatment combinations, and individual treatment analyses based on single-sample Student's <i>t</i>-tests showed different degrees of brain activation among channels and Brodmann areas. Meanwhile, a comparison of absolute values indicated that an illuminance level of 500 lx was more comfortable than levels of 300 and 800 lx, and that white color was more comfortable than bulb color and blue color. These results provide a scientific basis for the design of train cars that improve passenger comfort and satisfaction, which is anticipated to enhance the quality of railway services.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11946344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Leaching Characteristics of Heavy Metal Ions from Red Mud-Graphite Tailings.","authors":"Kangli Li, Xiaolei Lu, Congcong Jiang, Dan Wang, Jiang Zhu, Meiling Xu, Lina Zhang, Xin Cheng","doi":"10.3390/toxics13030211","DOIUrl":"10.3390/toxics13030211","url":null,"abstract":"<p><p>The rapid growth of aluminum and graphite industries has generated substantial stockpiles of red mud and graphite tailings, which pose environmental risks due to their high heavy metal content and potential for soil and water contamination. This study investigated the leaching behavior of heavy metals from these materials post-stabilization using cement and a sulfonated oil-based ion curing agent, thereby evaluating their suitability for safe reuse. Semi-dynamic leaching experiments were employed to measure heavy metal release, supplemented by kinetic modeling to discern key leaching mechanisms. The findings indicated that the heavy metal concentrations in leachates were consistently below regulatory standards, with leaching dynamics influenced by dual mechanisms: the diffusion of ions and surface chemical reactions. A diffusion coefficient-based analysis further suggested low leachability indices for all metals, confirming effective immobilization. These results suggest that cement and curing agent-stabilized red mud-graphite tailing composites reduce environmental risks and possess characteristics favorable for resource recovery, thus supporting their sustainable use in industrial applications.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11945629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Concentrations of Fipronil and Metabolites in Japanese Pregnant Women: Relationship with Thyroid Hormone Levels.","authors":"Kunishige Ikeda, Aya Hisada, Takamitsu Otake, Ryo Omagari, Daisuke Nakajima, Nobumasa Kato, Jun Yoshinaga","doi":"10.3390/toxics13030213","DOIUrl":"10.3390/toxics13030213","url":null,"abstract":"<p><p>Fipronil, a widely used phenylpyrazole insecticide, is known to disrupt circulating thyroid hormone (TH) levels in rodents. Concentrations of fipronil and its metabolites (fipronil sulfone and fipronil sulfide) in serum samples collected in 2009-2011 were measured for 131 Japanese pregnant women by a sensitive and accurate liquid chromatography-tandem mass spectrometric method developed in our laboratory to relate TH levels. Fipronil sulfone was detected in all the subjects with the median being 21 ng/L (min-max: 6.8-89), but fipronil and fipronil sulfide were detected in none of the subjects (detection limit: 5.0 and 1.2 ng/L, respectively), indicating a rapid and exclusive oxidative conversion to fipronil sulfone upon exposure. The median concentration of fipronil sulfone was lower than those previously reported for general populations in other countries by one order of magnitude. There were no attributes or dietary habits of the subjects that significantly vary the serum fipronil sulfone concentrations. Multiple regression analyses found no significant association between serum concentrations of fipronil sulfone and free thyroxine- or thyroid-stimulating hormone levels, indicating the absence of adverse effects on circulating TH levels probably due to the lower exposure levels of the present subjects. The present result would be valuable for establishing a dose-effect relationship of fipronils in humans on population levels.</p>","PeriodicalId":23195,"journal":{"name":"Toxics","volume":"13 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11945583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}