The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)最新文献_第5页

Dynamic attachment of HepG2 in fractal microchannels 分形微通道中HepG2的动态吸附

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908757

Lung-Jieh Yang, Jia-Chi Liang, Cheng-Yang Liu, Hsieh-Cheng Han

引用次数: 0

Digital fast startup procedure for micro-machined vibratory gyroscopes using optimized fuzzy control strategy 基于优化模糊控制策略的微加工振动陀螺仪数字快速启动程序

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908792

Long Wang, Qiancheng Zhao, Minghao Nie, Dachuan Liu, Yuxian Liu, Junjie Yan, Zhenchuan Yang, G. Yan

引用次数: 0

Measurement of glycated hemoglobin using an aptamer/antibody assay on an integrated microfluidic system 在集成微流控系统上使用适体/抗体测定糖化血红蛋白

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908895

K. Chang, Jing-Lun Li, Ching-Hsuan Yang, S. Shiesh, Gwo-Bin Lee

{"title":"Measurement of glycated hemoglobin using an aptamer/antibody assay on an integrated microfluidic system","authors":"K. Chang, Jing-Lun Li, Ching-Hsuan Yang, S. Shiesh, Gwo-Bin Lee","doi":"10.1109/NEMS.2014.6908895","DOIUrl":"https://doi.org/10.1109/NEMS.2014.6908895","url":null,"abstract":"Measurement of the ratio between glycated hemoglobin (HbA1c) and total hemoglobin (Hb) is now recommended for screening and diagnosing diabetes, in addition to monitoring long-term glycemic control for patient management. The costly and time-consuming traditional assay methods, which involve multi-step, bench-top, and antibody-based immunoassays, have presented major challenges to their clinical utility. In this study, an integrated microfluidic system capable of rapidly measuring the level of HbA1c and Hb in an automated fashion was reported. Moreover, this detection assay used nucleic acid aptamers that exhibited high sensitivity and specificity to Hb and HbA1c to further enhance the robustness of the assay. Combining the advantages of microfluidics and aptamers, this system presents a promising tool for clinical diagnosis and management of diabetes. As a demonstration of its clinical utility, we analyzed patient whole blood samples with clinically-relevant concentrations of HbA1c and Hb (4.4%-12.5% and 12.1 g/dL-14.9 g/dL, respectively) on our integrated microfluidic system.","PeriodicalId":22566,"journal":{"name":"The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"31 1","pages":"647-650"},"PeriodicalIF":0.0,"publicationDate":"2014-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87112241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

The fabrication of PDMS-based functional surface mimicking the namib desert beetle back for collecting water vapor in the air 基于pdms的纳米沙漠甲虫背部收集空气中水蒸气功能表面的制备

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908840

Wei Hu, Wen Liu, F. Zhu, Xiao-Sheng Zhang, Haixia Zhang

引用次数: 0

In-plane-excited silicon nanowire arrays-patterned cantilever sensors for enhanced airborne particulate matter exposure detection 平面内激发硅纳米线阵列模式悬臂传感器用于增强空气中颗粒物暴露检测

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908753

H. S. Wasisto, S. Merzsch, F. Steib, A. Waag, E. Peiner

{"title":"In-plane-excited silicon nanowire arrays-patterned cantilever sensors for enhanced airborne particulate matter exposure detection","authors":"H. S. Wasisto, S. Merzsch, F. Steib, A. Waag, E. Peiner","doi":"10.1109/NEMS.2014.6908753","DOIUrl":"https://doi.org/10.1109/NEMS.2014.6908753","url":null,"abstract":"This paper presents the design, fabrication, and use of silicon nanowire (SiNW) arrays-patterned microcantilever sensors excited in the in-plane resonance mode to enhance the detection of airborne particulate matter (PM). Electrothermal excitation elements of p-diffused heating resistors were introduced in the current sensor system to replace the formerly used external piezoceramic stack actuator. The sensors exhibited high measured quality factors (Q-factors) of 4702 ± 102 during their in-plane mode operations in air, which are four times larger than those of the fundamental out-of-plane mode. To selectively define arrays of vertical SiNWs on the surface of the micromechanical cantilever, nanoimprint lithography (NIL) is combined with conventional photolithography. The diameter and position of the SiNWs can be adjusted depending on the nanoimprint stamp with the smallest cylindrical pattern possible down to 50 nm in diameter. By modifying the resonator surface, the PM sampling efficiency can be improved by a factor of 1.5 greater than that of a corresponding plain cantilever in a cigarette smoke exposure experiment because of the rise in collection surface area of the sensor given by the SiNWs.","PeriodicalId":22566,"journal":{"name":"The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"15 1","pages":"32-37"},"PeriodicalIF":0.0,"publicationDate":"2014-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89519056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Detection of hazardous vapors including mixture in different conditions using surface acoustic wave device array 利用表面声波装置阵列对不同条件下的有害气体(包括混合气)进行检测

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908754

H. Hao, Ming-Chang Chiang, D. Yao

引用次数: 0

Using TD-GC-MS to analyze coffee beans aromas of different roast levels 采用TD-GC-MS对不同烘焙水平的咖啡豆香气进行分析

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908860

Chia-Hui Li, L. Chieng, Irrigepalli Srinivasa Thimmaraju, D. Yao

引用次数: 5

Molecular delivery and transfection by laser-induced oscillating microbubbles 激光诱导振荡微泡的分子传递和转染

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908813

Qihui Fan, Wenqi Hu, A. Ohta

引用次数: 0

Fabrication of through-silicon vias (TSV) by nickel electroplating in supercritical CO2 超临界CO2中电镀镍制备硅通孔(TSV)

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908770

H. Chuang, W. Lai, Chih-Chung Huang, A. Liao, C. Yeh

引用次数: 2

Multi-antibody array chip for immunoassay of different-grade bladder cancer cell lysates based on DEP manipulations of nanoprobes 基于纳米探针DEP操作的不同级别膀胱癌细胞裂解物免疫分析的多抗体阵列芯片

The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) Pub Date : 2014-04-13 DOI: 10.1109/NEMS.2014.6908889

C. Chuang, Jing-Wei Ju, Kai-Chieh Chang, Yao-Wei Huang, C. Jen

{"title":"Multi-antibody array chip for immunoassay of different-grade bladder cancer cell lysates based on DEP manipulations of nanoprobes","authors":"C. Chuang, Jing-Wei Ju, Kai-Chieh Chang, Yao-Wei Huang, C. Jen","doi":"10.1109/NEMS.2014.6908889","DOIUrl":"https://doi.org/10.1109/NEMS.2014.6908889","url":null,"abstract":"This paper develops a multi-antibody array biochip for detection of different-grade bladder cancer cell lysates based on protein expression level. Two nanoprobes modified with antibodies, Galectin-1 (Gal-1) and Lactate Dehydrogenase B (LDH-B), were immobilized in an array manner by sequent DEP manipulation steps including focusing, guiding and trapping, therefore, two different protein levels can be achieved in single chip without complex microchannel design. The structure of DEP chip consists of three electrode layers, top electrode made of Indium Tin Oxide (ITO), middle Au electrode on SU-8 surface for focusing and guiding of nanoprobes, and bottom ITO dot electrodes under SU-8 cavity for trapping of nanoprobes. In our experiments, two different grade bladder cancer cell lysates (grade I:RT4 and grade III:T24) were introduced into immunosensor, the expression levels of Gal-1 and LDH-B displayed different fluorescent responses for RT4 and T24 cell lysates. Accordingly, the fluorescence intensity of Gal-1 is higher than the value of LDH-B for T24 cell lysate; however, the response for RT4 is opposite, i.e. LDH-B > Gal-1. Consequently, determining of different-grade bladder cancer cell can be achieved by using present multi-antibody immunosensor. In addition, the DEP manipulations of nanoprobes also demonstrate the feasibility for multi-biomarker array in single chip for point-of-care diagnostics.","PeriodicalId":22566,"journal":{"name":"The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"39 1","pages":"626-627"},"PeriodicalIF":0.0,"publicationDate":"2014-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82243982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0