Sustainable Chemistry and Pharmacy最新文献

{"title":"Advanced characterization of sustainable exfoliating particles from food waste for facial scrub formulations and their in vivo evaluation","authors":"Camilla Elena Di Bella ,&nbsp;Chiara D'Agostino ,&nbsp;Dolores Vargas Peregrina ,&nbsp;Maria Rosa Gigliobianco","doi":"10.1016/j.scp.2025.101953","DOIUrl":"10.1016/j.scp.2025.101953","url":null,"abstract":"<div><div>Public opinion is increasingly interested in environmental issues and the state of health of the planet. As the economic system continues to go through a process of continual change, the most important problem is to plan for a sustainable future. This research presents a well-defined experimental strategy for converting food waste into cosmetic products, particularly face scrub formulations, by employing, whenever possible, ingredients from natural sources. Food and agricultural waste, such as coffee grounds (CF), malt residue (TM), hop remnants (HS), pomegranate leftovers (WF and MF), and pomace (WP and WL), were used in this work as source products for creating mechanical cosmetic scrubbing. The samples were subjected to drying, grinding, and sieving to generate powders with varying grain sizes showing particles with diameters between 420 and 707 μm for CF, TM, WL, HS, and WF samples and 1000 μm for MF and WP samples.</div><div>An optical microscope study determined every sieved fraction's size, shape, and surface properties. Following the assessment of powder wettability, the chosen samples were used as green exfoliating particles (GEP) to formulate lipogel-based facial scrubs. The lipogels were characterised by their physicochemical properties, microbial stability and <em>in vivo</em> efficacy. For all the formulations, a marked reduction in the sebum was observed at t30, which was only partially restored at t60. Results in the transepidermal water loss (TEWL) among all the formulations and at different time points confirmed that the skin barrier integrity is not affected by mechanical exfoliation, also encountering the volunteers' appreciation.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101953"},"PeriodicalIF":5.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic potential of thymol and red cabbage anthocyanin in biodegradable cellulose acetate labels for active and intelligent freshness monitoring of homemade tomato sauces","authors":"Abderrahim Bouftou ,&nbsp;Doha Belfadil ,&nbsp;Kaoutar Aghmih ,&nbsp;Fatima Lakhdar ,&nbsp;Said Gmouh ,&nbsp;Sanaa Majid","doi":"10.1016/j.scp.2025.101947","DOIUrl":"10.1016/j.scp.2025.101947","url":null,"abstract":"<div><div>Colorimetric labels were developed using cellulose acetate (CA) as a base matrix in the presence of red cabbage anthocyanins (ANT) as a natural colorant and thymol (THY) as an active agent. CA/THY/ANT labels with different concentrations of ANT were prepared using the solvent evaporation method, to control food freshness and improve shelf life. The prepared labels were characterized by FTIR, SEM and other techniques. Anthocyanin-rich red cabbage extract confers to the labels a clear, stable and reversible color response in a pH range between 2 and 12, and average antioxidant properties. Thymol was added to the label as natural food preservative. The antibacterial properties against the pathogens tested were improved, without affecting the clear coloration of the labels and their response. To validate the use of these labels as an indicator of tomato sauce freshness, application tests were carried out on natural tomato sauces. The labels showed improved sensitivity to pH changes and a beneficial effect on the acidity and color of tomato sauce during storage. When tomato sauce deteriorates and loses its freshness, its pH becomes more basic, and its color darkens. The labels revealed a reduction in the bacterial load in the tomato sauce during storage at different temperatures, and as a result the tomato sauce maintains its pH and colour. The labels demonstrated also a possibility of reuse, by regeneration of the initial color. These results confirmed the possibility of using these new smart label to control freshness and extend the shelf life of foods.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101947"},"PeriodicalIF":5.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using green solvents as co-solvent in supercritical carbon dioxide extraction: A promising source of extracts rich in antioxidants and antimicrobials agents","authors":"Hamza bouakline ,&nbsp;Imane Ziani ,&nbsp;Meryem Idrissi Yahyaoui ,&nbsp;Francesco Corrias ,&nbsp;Asehraou Abdeslam ,&nbsp;Ali El Bachiri","doi":"10.1016/j.scp.2025.101950","DOIUrl":"10.1016/j.scp.2025.101950","url":null,"abstract":"<div><div>Investigation of supercritical CO₂ extraction and CO₂ mixture with \"modified\" co-solvent (10%) as an environmentally friendly technology for the extraction of bioactive compounds from fresh and dried leaves of <em>Pistacia lentiscus</em>. The different <em>Pistacia lentiscus</em> leaves extracts were obtained at 150 bar, 45 °C, the ethanol and water were utilized as co-solvents to support the polarity of supercritical carbon dioxide extraction (SFE-CO₂). The extraction efficiency, chemical compositions, total phenols and flavonoids content, antioxidants and antimicrobials activities have been compared using the both approach the pure CO₂ and modifier CO₂, for the fresh and dried <em>Pistacia lentiscus</em> leaves. As results, concerning the extraction yield, chemical composition, and total polyphenol and flavonoid content exhibited significant variations. As well as the SFE-CO₂ extracts modified by water showed important antioxidants activity compared to simple SFE-CO₂ extraction. In adverse the pure SFE-CO₂ extraction showed important antimicrobials activity compared to the SFE-CO₂ extracts modified by co-solvent.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101950"},"PeriodicalIF":5.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Furans derived from lignocellulosic biomass as renewable substrates in multicomponent reactions","authors":"Gabriel Abranches Dias Castro,&nbsp;Sergio Antonio Fernandes","doi":"10.1016/j.scp.2025.101948","DOIUrl":"10.1016/j.scp.2025.101948","url":null,"abstract":"<div><div>Multicomponent reactions (MCRs) are a powerful and efficient tool for organic synthesis, where three or more substrates react to form a more complex product in a single step. They have been essential for the synthesis of new drugs and materials, and are widely promoted from the perspective of sustainable chemistry, since, compared to chemical processes carried out in stages, they save time and resources, in addition to generating less waste. However, furan compounds derived from lignocellulosic biomass are still little explored in MCRs as substrates. This is particularly promising because these compounds are renewable and lignocellulosic biomass is one of the most abundant raw materials in the world. Furthermore, in general, research on innovation in chemical processes has been moving towards the replacement of chemical inputs derived from petroleum by materials from renewable sources. This short review highlights the key aspects of the use of furans derived from lignocellulosic biomass as substrates in MCRs.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101948"},"PeriodicalIF":5.5,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coordination engineering of transition metal doped in B2CN3 electrocatalyst to enhance efficient carbon dioxide reduction reaction","authors":"Waqed H. Hassan ,&nbsp;Anjan Kumar ,&nbsp;G.V. Siva Prasad ,&nbsp;Bhanu Juneja ,&nbsp;Muna Salih Merza ,&nbsp;Abdulrahman A. Almehizia ,&nbsp;Devendra Pratap Rao ,&nbsp;Chou-Yi Hsu","doi":"10.1016/j.scp.2025.101951","DOIUrl":"10.1016/j.scp.2025.101951","url":null,"abstract":"<div><div>One of the effective strategies adopted for mitigating the challenges posed by the elevated emission of CO₂ is its electrochemical reduction into valuable products. This work employs DFT to investigate a transition metal-doped B₂CN₃ electrocatalyst, which is one of the significantly selective and stable electrocatalysts for the carbon dioxide reduction reaction (CRR). Various transition metals, including cobalt, chromium, iron, and nickel, were utilized for doping to explore different electrocatalysts. The DFT indicated that the Fe–B₂CN₃ effectively adhered and activated CO₂, as confirmed by analyses of the crystal orbital Hamilton population, Bader charge, charge density differences and partial density of states. The limiting potential for CRR was −0.41 V, in contrast to the hydrogen evolution reaction (HER) at −0.244 V, with formaldehyde identified as the primary product. The B₂CN₃ exhibited a preference for CO₂ reduction while effectively suppressing the HER. This research highlights the promising application of the modified B₂CN₃ as a highly-efficient electrocatalyst for CRR and offers invaluable theoretical insights for designing efficient CRR electrocatalysts.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101951"},"PeriodicalIF":5.5,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel geotechnical properties of lime-stabilized clay strength via hydrothermal solidification: Impact of leaching coefficient, chemical interactions, and silica-sesquioxide ratio for sustainable Geotechnics","authors":"Shifa Burhan,&nbsp;Ahmed Salih Mohammed","doi":"10.1016/j.scp.2025.101929","DOIUrl":"10.1016/j.scp.2025.101929","url":null,"abstract":"<div><div>Hydrothermal solidification offers an effective, sustainable method for stabilizing clay soil, addressing environmental concerns while improving geotechnical properties. Facilitating pozzolanic reactions between lime and clay under controlled temperature and pressure significantly enhances compressive strength and soil durability. This process promotes calcium silicate hydrate (C–S–H) formation, reduces industrial waste, and supports lime reuse, making it an energy-efficient soil improvement approach. This study investigates the impact of lime addition (0–20%) and various chemical and physical parameters on clay soil compressive strength. Key chemical components include SiO₂ (20.1–76.9%), Al₂O₃ (7.6–34.8%), Fe₂O₃ (0.6–32.9%), CaO (0.1–43.5%), MgO (0–9.56%), Na₂O (0.01–2.8%), and K₂O (0.1–3.9%). Physical properties such as density, plasticity index (6–34.5%), and liquid limit (24–65.2%) were analyzed alongside process parameters like heating temperature (60–1000 °C), curing time (0–120 days), and curing temperature (20–41 °C). Using a dataset of 152 samples divided into training and testing groups, the statistical analysis focused on the leaching coefficient (Lc) and silica-sesquioxide ratio (Kr). Lc emerged as the most significant factor, achieving an R² of 0.89 and an RMSE of 1.13 MPa. This study found that the compressive strength of lime-treated clay soils varied from 0.02 MPa to 11.9 MPa, influenced by lime concentration, chemical composition, and processing factors. Increased lime additions, particularly when combined with hydrothermal treatment, led to significant strength enhancements owing to improved pozzolanic activity. The plasticity index (PI) markedly diminished with lime stabilization, enhancing workability and mitigating volumetric variations. The density of treated soils rose from 0.8 g/cm³ to 2.1 g/cm³, signifying improved particle compaction and less porosity. The mechanical enhancements indicate that hydrothermal solidification efficiently converts expanding clay into a robust and stable material appropriate for geotechnical applications. Increased Lc improved compressive strength through enhanced pozzolanic activity and density, while higher Kr values, indicating lower CaO availability, yielded limited strength gains. Lc consistently outperformed Kr and other chemical compositions in enhancing clay soil compressive strength.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101929"},"PeriodicalIF":5.5,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"60Co-γ-ray-irradiated edible silkworm (Bombyx mori) pupae-assisted protease digestion: A strategy for obtaining low molecular weight bioactive peptides","authors":"Xiao-Meng Xun ,&nbsp;Cheng-Hai Yan ,&nbsp;Zi-Xuan Yuan ,&nbsp;Zhi-Ang Zhang ,&nbsp;Richard Ansah Herman ,&nbsp;Yan Xu ,&nbsp;Qiong-Ying Wu ,&nbsp;Jun Wang","doi":"10.1016/j.scp.2025.101941","DOIUrl":"10.1016/j.scp.2025.101941","url":null,"abstract":"<div><div>Bioactive peptides from edible insect protein are a class of peptide compounds with relatively low molecular weight, possessing specific biological activity functions, but their extraction and utilization face challenges. The study aims to explore a novel approach using ⁶⁰Co-<em>γ</em>-ray irradiation-assisted enzymatic hydrolysis of silkworm pupae protein to obtain bioactive peptides. The silkworm pupae were irradiated with ⁶⁰Co-<em>γ</em>-ray at a dose point of 10 kGy, and then the protein was extracted and subsequently hydrolyzed by alkaline protease, and the irradiated silkworm pupae protein improved solubility and hydrolysis degree. The proportion of <em>α</em>-helix in the secondary structure of the irradiated silkworm pupae protein increases, indicating that irradiation can enhance its functional properties by altering the intrinsic structure. Through irradiation-assisted enzymatic hydrolysis, The percentage of low molecular weight peptides (180–500 Da) prepared by irradiation-coupled enzymatic hydrolysis increased from 32.04 ± 0.97% to 52.77 ± 0.72%, and the percentage of low molecular weight peptides (0.5–1 kDa) increased from 19.65 ± 0.52% to 24.75 ± 0.79%. Activity-guided isolation and identification reveal a greater diversity of peptides with antioxidant, hypoglycemic, and hypotensive activities in the irradiated group, including novel peptides such as QASSGTPATLR, LLPR, FKVPN, and HHFP that exhibit strong scavenging activity against DPPH radicals, <em>α</em>-glucosidase inhibition, Fe²⁺ chelation, and angiotensin-converting enzyme (ACE) inhibition. Molecular docking simulations shown that the irradiated peptides have enhanced affinity for target enzymes, suggesting that the ⁶⁰Co-<em>γ</em>-ray irradiation-assisted enzymatic hydrolysis technique can effectively improve peptide activity. This study provides a theoretical basis for irradiation-assisted enzymatic degradation of edible insect proteins to obtain low molecular weight bioactive peptides.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101941"},"PeriodicalIF":5.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable valorization of onion (Allium cepa L) skin as a resource for value-added products: A comprehensive review","authors":"Sampson Kofi Kyei ,&nbsp;William Iheanyi Eke ,&nbsp;Alex Justice Frimpong ,&nbsp;Robert Dery Nagre ,&nbsp;Onyewuchi Akaranta","doi":"10.1016/j.scp.2025.101942","DOIUrl":"10.1016/j.scp.2025.101942","url":null,"abstract":"<div><div>The valorization of industrial waste through sustainable methods aimed at converting it into higher-value products has garnered significant attention owing to increasing issues related to climate change and the exhaustion of non-renewable resources. This review addresses the utilization of onion skin waste to produce valuable goods, promoting a circular economy and eco-friendly resource utilization. It aims to appraise the possible uses of several different extraction methods for obtaining bioactive chemicals out of onion skin waste and evaluates their efficiencies to highlight their potential as industrial raw materials for sustainable development. Moreover, this review examines a multidisciplinary method for valorizing onion skin as a possible resource for various industrial applications and other therapeutic applications linked to their anticancer, antimicrobial, antioxidant, anti-inflammatory, antidiabetic, and neuroprotective activities. This approach encourages the recycling and reuse of biomass while delivering a substitute for traditional extraction methods, thereby supporting the broader goals of sustainable chemistry. The review will advance studies on onion skin waste and improve industrial applications.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101942"},"PeriodicalIF":5.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143272013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The journey towards an inclusive green chemistry education community of practice by prioritizing diversity, equity, belonging, and respect for an open-access online platform","authors":"Nimrat K. Obhi ,&nbsp;Jonathon Moir ,&nbsp;Andrea Oseolorun ,&nbsp;Amy S. Cannon","doi":"10.1016/j.scp.2025.101944","DOIUrl":"10.1016/j.scp.2025.101944","url":null,"abstract":"<div><div>Green chemistry education is essential for the widespread adoption of chemical practices that prioritize benign product design and minimize adverse impacts to health and our environment. Open-access resource dissemination and provision of community spaces for peer-to-peer support and mentorship are critical to supporting universal green chemistry adoption and fostering a green chemistry education community of practice to transform chemistry education worldwide. The Green Chemistry Teaching and Learning Community (GCTLC) was launched by Beyond Benign and the American Chemical Society Green Chemistry Institute (ACS GCI) as a free online website to support a green chemistry education community of practice. Diversity, equity, belonging, and respect (DEBR) principles and practices were key to the design and development of the GCTLC to ensure platform functionalities and features remain inclusive, accessible, and promote a strong sense of belonging for users. This article describes the framework for the integration of DEBR principles and practices throughout every aspect of the design, development, and launch of this online platform. We additionally discuss features and functionalities of the GCTLC that resulted from using this framework to design the platform. Through this report, we ultimately discuss steps taken to intentionally create an inclusive and welcoming community of practice for educators seeking resources and peer-to-peer support in making green chemistry an essential part of science education.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101944"},"PeriodicalIF":5.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From fly ashes of lignocellulose waste combustion to sustainable activated carbons for VOCs removal","authors":"B. Ruiz ,&nbsp;Alba Cabrera-Codony ,&nbsp;R.P. Girón ,&nbsp;Alba Anfruns ,&nbsp;Maria J. Martín ,&nbsp;I. Suárez-Ruiz ,&nbsp;E. Fuente","doi":"10.1016/j.scp.2025.101943","DOIUrl":"10.1016/j.scp.2025.101943","url":null,"abstract":"","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"44 ","pages":"Article 101943"},"PeriodicalIF":5.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143271255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}