Hosein Nouri , Seyed-Hossein Abtahi , Mehdi Mazloumi , Sanam Samadikhadem , J. Fernando Arevalo , Hamid Ahmadieh
{"title":"Optical coherence tomography angiography in diabetic retinopathy: A major review","authors":"Hosein Nouri , Seyed-Hossein Abtahi , Mehdi Mazloumi , Sanam Samadikhadem , J. Fernando Arevalo , Hamid Ahmadieh","doi":"10.1016/j.survophthal.2024.03.004","DOIUrl":"10.1016/j.survophthal.2024.03.004","url":null,"abstract":"<div><p>Diabetic retinopathy (DR) is characterized by retinal vasculopathy and is a leading cause of visual impairment. Optical coherence tomography angiography (OCTA) is an innovative imaging technology that can detect various pathologies and quantifiable changes in retinal microvasculature. We briefly describe its functional principles and advantages over fluorescein angiography and perform a comprehensive review on its clinical applications in the screening or management of people with prediabetes, diabetes without clinical retinopathy (NDR), nonproliferative DR (NPDR), proliferative DR (PDR), and diabetic macular edema (DME). OCTA reveals early microvascular alterations in prediabetic and NDR eyes, which may coexist with sub-clinical neuroretinal dysfunction. Its applications in NPDR include measuring ischemia, detecting retinal neovascularization, and timing of early treatment through predicting the risk of retinopathy worsening or development of DME. In PDR, OCTA helps characterize the flow within neovascular complexes and evaluate their progression or regression in response to treatment. In eyes with DME, OCTA perfusion parameters may be of predictive value regarding the visual and anatomical gains associated with treatment. We further discussed the limitations of OCTA and the benefits of its incorporation into an updated DR severity scale.</p></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 4","pages":"Pages 558-574"},"PeriodicalIF":5.1,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140194593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neil M. Bressler , Peter K. Kaiser , Diana V. Do , Quan Dong Nguyen , Kyu Hyung Park , Se Joon Woo , Min Sagong , Mario Bradvica , Mercy Yeeun Kim , Seungkee Kim , SriniVas R. Sadda
{"title":"Biosimilars of anti-vascular endothelial growth factor for ophthalmic diseases: A review","authors":"Neil M. Bressler , Peter K. Kaiser , Diana V. Do , Quan Dong Nguyen , Kyu Hyung Park , Se Joon Woo , Min Sagong , Mario Bradvica , Mercy Yeeun Kim , Seungkee Kim , SriniVas R. Sadda","doi":"10.1016/j.survophthal.2024.03.009","DOIUrl":"10.1016/j.survophthal.2024.03.009","url":null,"abstract":"<div><p>The development of intravitreally injected biologic medicines (biologics) acting against vascular endothelial growth factor (VEGF) substantially improved the clinical outcomes of patients with common VEGF-driven retinal diseases. The relatively high cost of branded agents, however, represents a financial burden for most healthcare systems and patients, likely resulting in impaired access to treatment and poorer clinical outcomes for some patients. Biosimilar medicines (biosimilars) are clinically equivalent, potentially economic alternatives to reference products. Biosimilars approved by leading health authorities have been demonstrated to be similar to the reference product in a comprehensive comparability exercise, generating the totality of evidence necessary to support analytical, pre-clinical, and clinical biosimilarity. Anti-VEGF biosimilars have been entering the field of ophthalmology in the US since 2022. We review regulatory and scientific concepts of biosimilars, the biosimilar development landscape in ophthalmology, with a specific focus on anti-VEGF biosimilars, and discuss opportunities and challenges facing the uptake of biosimilars.</p></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 4","pages":"Pages 521-538"},"PeriodicalIF":5.1,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0039625724000298/pdfft?md5=3d98e8329dfc4dcfb85d696499bf50e5&pid=1-s2.0-S0039625724000298-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140194592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariska Scheffer , Juliane Menting , Hennie Boeije , Ruth van Nispen , Sandra van Dulmen
{"title":"Understanding healthcare communication in age-related macular degeneration care: A mixed-methods review of patients’ perspectives","authors":"Mariska Scheffer , Juliane Menting , Hennie Boeije , Ruth van Nispen , Sandra van Dulmen","doi":"10.1016/j.survophthal.2024.03.002","DOIUrl":"10.1016/j.survophthal.2024.03.002","url":null,"abstract":"<div><p>Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment among people aged 50 years and older. Earlier research has indicated that the communication process between patients and healthcare professionals (HCPs) leaves considerable room for improvement in AMD care. Effective communication is essential to enhance trust in the professional and understanding of the diagnosis and treatment, and decrease anxiety and stress related to illness. We review patients’ experiences, needs and preferences regarding information provision, communication style of the HCP and shared decision-making. We conducted a systematic search in PubMed, Embase, PsycINFO, CINAHL and Web of Science. Study quality was assessed using standard checklists of quality measures. Our search returned 31 eligible articles. Findings indicated current deficits in information provision for people with AMD. Patients were often ill-informed regarding the chronic character of the condition, treatment duration, nutrition, and visual aids and low vision rehabilitation. Many patients were not actively involved during the decision-making process. Altogether, patients with AMD are faced with challenges in terms of patient-HCP communication. Methods of providing information and discussing possible options for care need to be further investigated and improved for this patient group.</p></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 4","pages":"Pages 646-660"},"PeriodicalIF":5.1,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0039625724000183/pdfft?md5=de4b58e9b73c0ab6eefe5c5a258f3ba9&pid=1-s2.0-S0039625724000183-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hongkang Wu , Kai Jin , Chee Chew Yip , Victor Koh , Juan Ye
{"title":"A systematic review of economic evaluation of artificial intelligence-based screening for eye diseases: From possibility to reality","authors":"Hongkang Wu , Kai Jin , Chee Chew Yip , Victor Koh , Juan Ye","doi":"10.1016/j.survophthal.2024.03.008","DOIUrl":"10.1016/j.survophthal.2024.03.008","url":null,"abstract":"<div><p>Artificial Intelligence (AI) has become a focus of research in the rapidly evolving field of ophthalmology. Nevertheless, there is a lack of systematic studies on the health economics of AI in this field. We examine studies from the PubMed, Google Scholar, and Web of Science databases that employed quantitative analysis, retrieved up to July 2023. Most of the studies indicate that AI leads to cost savings and improved efficiency in ophthalmology. On the other hand, some studies suggest that using AI in healthcare may raise costs for patients, especially when taking into account factors such as labor costs, infrastructure, and patient adherence. Future research should cover a wider range of ophthalmic diseases beyond common eye conditions. Moreover, conducting extensive health economic research, designed to collect data relevant to its own context, is imperative.</p></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 4","pages":"Pages 499-507"},"PeriodicalIF":5.1,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0039625724000250/pdfft?md5=79f6dd094ed937590fca0bbb1338be40&pid=1-s2.0-S0039625724000250-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140140854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Sabatino , Philip Banerjee , Mahiul M. K. Muqit
{"title":"Clinical therapeutics for proliferative vitreoretinopathy in retinal detachment","authors":"Francesco Sabatino , Philip Banerjee , Mahiul M. K. Muqit","doi":"10.1016/j.survophthal.2024.03.007","DOIUrl":"10.1016/j.survophthal.2024.03.007","url":null,"abstract":"<div><p>Proliferative vitreoretinopathy (PVR) is an abnormal and prolonged healing response to retinal injury (retinal detachment, post retinal detachment surgery) characterised by: pre/subretinal membrane formation; retinal gliosis and retinal shortening, retinal pigment epithelium cell proliferation; and increased glial (mainly Mu¨ller cells), fibroblast and inflammatory cell (macrophage, lymphocyte) activity, leading to tractional retinal holes/breaks and multiple costly eye operations suffered by patients. PVR can cause retinal re-detachment following primary surgical intervention for rhegmatogenous retinal detachment. Vitrectomy and scleral buckling surgery are the main approaches for treating PVR complications of retinal detachment. Patients require many operations to remove the scar tissue but vision results are suboptimal, and do not meet patient expectations. Over the past 40 years, this has been one of the greatest challenges for vitreoretinal surgeons and patients. Despite previous large clinical trials of multiple candidate drug therapeutics, no proven adjunctive treatment currently exists to either prevent, reduce, or treat PVR formation in retinal detachment. Both cellular proliferation and the intraocular inflammatory response are realistic targets for adjunctive treatments in PVR. The cellular components of PVR periretinal membranes (retinal pigment epithelial, glial, inflammatory and fibroblastic cells) proliferate and are thus targets for antiproliferative agents. In recent years, several new therapeutics have been tested, and we present an updated review of the clinical therapeutics for PVR in retinal detachment.</p></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 4","pages":"Pages 508-520"},"PeriodicalIF":5.1,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140140855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Layla J. Bunjo , Stephen Bacchi , James Pietris , Weng Onn Chan
{"title":"Current management options for the treatment of refractory postoperative cystoid macular edema: A systematic review","authors":"Layla J. Bunjo , Stephen Bacchi , James Pietris , Weng Onn Chan","doi":"10.1016/j.survophthal.2024.03.005","DOIUrl":"10.1016/j.survophthal.2024.03.005","url":null,"abstract":"<div><p>Post-operative cystoid macular edema (PCME) is an important complication following intraocular surgery that often resolves spontaneously without treatment. In some cases, PCME may persist despite initial medical therapy, which can adversely impact visual outcomes. Various topical, intraocular and systemic treatments exist for the prevention and management of cystoid macular edema; however, there is no consensus on treatment of refractory cases in the postoperative setting. In accordance with the PRISMA guidelines, we systematically reviewed 68 articles describing management options and their outcomes for treatment-resistant cases of PCME. The most commonly reported treatments included steroid (39 studies) and biological-based (17 studies) therapies. We provide an overview of the treatment options for refractory PCME.</p></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 4","pages":"Pages 606-621"},"PeriodicalIF":5.1,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luke Leidy , Anna Dickinson , Pradeep Ramulu , Joshua Ehrlich , Mona A. Kaleem
{"title":"Clinical outcome measures in vision and eye care","authors":"Luke Leidy , Anna Dickinson , Pradeep Ramulu , Joshua Ehrlich , Mona A. Kaleem","doi":"10.1016/j.survophthal.2024.03.006","DOIUrl":"10.1016/j.survophthal.2024.03.006","url":null,"abstract":"<div><p>Traditionally, clinical outcome assessments have focused on the patient’s perspective through patient-reported outcome assessments; however, given the complexity, integration, and interactions of various participants within the clinical ophthalmology setting, we propose that additional diverse clinical perspectives should be explored in order to appreciate fully the value of care provided to patients. In this review we introduce a framework by which clinical outcome assessments (COAs) can be organized. Our COA framework is composed of five outcome measurements that encompass the perspectives of each player in a patient’s care: clinical data-reported outcomes, patient-reported outcomes, clinician-reported outcomes, observer-reported outcomes, and reviewer-reported outcomes. By establishing a standard for evaluating patient care, we hope to address gaps in expectations of patient care and encourage more thoughtful patient-clinician relationships.</p></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 4","pages":"Pages 632-637"},"PeriodicalIF":5.1,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140132628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Terence Ang MBBS , Viraj Chaggar , Jessica Y. Tong FRANZCO , Dinesh Selva DHSc FRANZCO FRACS
{"title":"Medication-associated orbital inflammation: A systematic review","authors":"Terence Ang MBBS , Viraj Chaggar , Jessica Y. Tong FRANZCO , Dinesh Selva DHSc FRANZCO FRACS","doi":"10.1016/j.survophthal.2024.03.003","DOIUrl":"10.1016/j.survophthal.2024.03.003","url":null,"abstract":"<div><p>We performed a comprehensive systematic review to identify medication-associated orbital inflammation and to characterize its clinico-radiological features. We reviewed English-language articles describing medication-associated orbital inflammation (i.e., orbital myositis, dacryoadenitis and orbital fat) published to June, 2023. Isolated inflammation of the intraocular structures or globe alone (i.e. uveitis, scleritis, optic neuritis and perineuritis) were excluded. In medication-associated orbital inflammation, the extraocular muscles are preferentially affected, occurring in isolation or in combination with other orbital and/or intraocular structures. Clinico-radiological manifestations may be non-specific; however, certain medications may be distinguished according to the presence of systemic prodrome, laterality, associated intraocular inflammation, and predisposition to involve certain orbital structures. Rapid identification, discontinuation of the provoking medication, and systemic corticosteroid therapy (if appropriate) typically achieves a favorable visual prognosis. As new medications become adopted by clinicians, rare adverse effects will be further delineated.Medication-associated orbital inflammation is an important diagnostic consideration in orbital inflammatory disease. A careful medication history and clinical assessment may be revealing, permitting timely discontinuation of the offending agent and initiation of appropriate management.</p></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 4","pages":"Pages 622-631"},"PeriodicalIF":5.1,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0039625724000201/pdfft?md5=fa20309de7d4dc0ecb51ae16a8b32310&pid=1-s2.0-S0039625724000201-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical and anesthetic influences of the oculocardiac reflex in adults and children during strabismus surgery","authors":"Robert W. Arnold MD","doi":"10.1016/j.survophthal.2023.06.005","DOIUrl":"10.1016/j.survophthal.2023.06.005","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"69 2","pages":"Page 295"},"PeriodicalIF":5.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9637123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}