An update on ocular effects of antidiabetic medications.

IF 5.1 2区医学 Q1 OPHTHALMOLOGY

Survey of ophthalmology Pub Date : 2025-01-22 DOI:10.1016/j.survophthal.2025.01.010

Elham Sadeghi, Elham Rahmanipour, Nicola Valsecchi, Saloni Kapoor, Maria Vittoria Cicinelli, Jay Chhablani

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引用次数: 0

Abstract

The global increase in the prevalence of type 2 diabetes has led to the development and implementation of new classes of antidiabetic medications, introducing advanced therapeutic options for the management of the disease. These new medications, though primarily designed to regulate blood glucose levels, also have applications in weight management, potentially transforming the current approaches to diabetes treatment. Newer medications, however, have ophthalmic side effects with controversies in trials and real-life data. We comprehensively assessed the ocular benefits and adverse effects of traditional and newer-generation anti-diabetic drugs. Our primary focus is on how these newer medications affect the stage of diabetic retinopathy. Additionally, we explore the associations between these medications and other ocular conditions, including age-related macular degeneration, glaucoma, orbital conditions, and diseases impacting the ocular surface. Furthermore, we provide contextual background by discussing the ocular effects of traditional anti-diabetic drugs.

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抗糖尿病药物眼部作用的最新进展。

全球2型糖尿病患病率的增加导致了新型抗糖尿病药物的开发和实施，为该疾病的管理引入了先进的治疗选择。这些新药物虽然主要用于调节血糖水平，但在体重管理方面也有应用，可能会改变目前治疗糖尿病的方法。然而，较新的药物有眼部副作用，在试验和实际数据中存在争议。我们对传统和新一代抗糖尿病药物的眼部益处和不良反应进行了综合评估。我们主要关注的是这些新药物如何影响糖尿病视网膜病变的阶段。此外，我们还探讨了这些药物与其他眼部疾病之间的关系，包括年龄相关性黄斑变性、青光眼、眼窝状况和影响眼表的疾病。此外，我们通过讨论传统抗糖尿病药物的眼部作用提供背景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Survey of ophthalmology 医学-眼科学

CiteScore

10.30

自引率

2.00%

发文量

138

审稿时长

14.8 weeks

期刊介绍： Survey of Ophthalmology is a clinically oriented review journal designed to keep ophthalmologists up to date. Comprehensive major review articles, written by experts and stringently refereed, integrate the literature on subjects selected for their clinical importance. Survey also includes feature articles, section reviews, book reviews, and abstracts.