Jennifer K. Dunnigan BS , Celeste Y. Wang BA , Livia George BS , Virginia A. Lee , Kevin E. Lai MD , Andrew R. Carey MD , Andrew G. Lee MD
{"title":"Social media in ophthalmology: A comprehensive literature review","authors":"Jennifer K. Dunnigan BS , Celeste Y. Wang BA , Livia George BS , Virginia A. Lee , Kevin E. Lai MD , Andrew R. Carey MD , Andrew G. Lee MD","doi":"10.1016/j.survophthal.2025.02.003","DOIUrl":"10.1016/j.survophthal.2025.02.003","url":null,"abstract":"<div><div>We examine the role of social media in ophthalmology, focusing on its impact on patient education, professional networking, and practice promotion. An English language, PubMed search from 2019 to 2024 was performed using the search terms: “social media” and “ophthalmology” on PubMed. An analysis based on the existing usage patterns and impact/effect of social media platforms in ophthalmology was performed and is described. Fifty-five papers were included in the review. Social media enhance patient engagement and education with varying content quality. Platforms like X and YouTube have the potential to offer valuable educational content, while Instagram and TikTok foster interactive user engagement. Despite these benefits, misinformation, patient confidentiality, and time commitment remain a considerable issue. Social media provide substantial advantages for ophthalmologists, but requires careful management to address the spread of inaccurate information and ensure content quality.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 817-824"},"PeriodicalIF":5.1,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sadegh Ghafarian , Bijan Samavat , Karen Lee , Sima Sheikhghomi , Kasra Cheraghpour , Deepak Shukla , Ali R. Djalilian , James Chodosh , Mohammad Soleimani
{"title":"Clinical strategies to prevent recurrence of Herpes simplex and Herpes zoster following ocular surgery: A comprehensive review with practical guidelines","authors":"Sadegh Ghafarian , Bijan Samavat , Karen Lee , Sima Sheikhghomi , Kasra Cheraghpour , Deepak Shukla , Ali R. Djalilian , James Chodosh , Mohammad Soleimani","doi":"10.1016/j.survophthal.2025.02.002","DOIUrl":"10.1016/j.survophthal.2025.02.002","url":null,"abstract":"<div><div>Recurrences of herpetic infections following intraocular surgeries pose a threat to optimal surgical outcomes. The high prevalence of herpetic diseases require ophthalmologists to be familiar with the special measures in the surgery of these patients. A thorough preoperative assessment and meticulous postoperative surveillance should be tailored for each patient, depending on the surgery and the risk of virus reactivation. We compile the relevant evidence in the literature and provide a comprehensive review of the preoperative assessment and postoperative diagnostic clues and management of the herpetic infections following different types of intraocular surgeries, including cataract surgery, keratoplasty, corneal crosslinking, glaucoma, and refractive surgeries.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 734-755"},"PeriodicalIF":5.1,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kambiz Ameli , Jacqueline M. Ihinger , Michael S. Lee , Andrew R. Carey
{"title":"If at first you don’t succeed, try, try again","authors":"Kambiz Ameli , Jacqueline M. Ihinger , Michael S. Lee , Andrew R. Carey","doi":"10.1016/j.survophthal.2025.01.011","DOIUrl":"10.1016/j.survophthal.2025.01.011","url":null,"abstract":"<div><div>A previously healthy 15-year-old Asian boy presented with progressive bilateral painless vision loss, dyschromatopsia, and visual field defects. Optical coherence tomography showed diffuse retinal nerve fiber layer thinning. Work-up including neuroimaging, lab testing for acquired bilateral optic atrophy, extensive mitochondrial and nuclear genetic testing yielded negative results. Several years after initial presentation, his paternal uncle tested positive for an autosomal dominant variant in the Ubiquitin C-terminal hydrolase L1 (<em>UCHL1</em>) gene. This led to reanalysis of the patient’s previous exome sequencing data that identified the familial pathogenic variant in the <em>UCHL1</em> gene, which has been associated with optic atrophy.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 840-844"},"PeriodicalIF":5.1,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matteo Mario Carlà MD, FEBO , Federico Giannuzzi MD, FEBO , Francesco Boselli MD, FEBO , Carlos Mateo MD , Tomaso Caporossi MD, PhD , Stanislao Rizzo MD
{"title":"The applications of viscoelastic agents in vitreoretinal surgery","authors":"Matteo Mario Carlà MD, FEBO , Federico Giannuzzi MD, FEBO , Francesco Boselli MD, FEBO , Carlos Mateo MD , Tomaso Caporossi MD, PhD , Stanislao Rizzo MD","doi":"10.1016/j.survophthal.2025.02.001","DOIUrl":"10.1016/j.survophthal.2025.02.001","url":null,"abstract":"<div><div>The introduction of viscoelastics in human ocular surgery dates back to 1972.Subsequntly, several substances were proposed as adjuvants, particularly for cataract surgery; however, the rheologic properties of ophthalmic viscosurgical devices (OVDs), such as viscosity, pseudoplasticity, and coatability led to their employment also in vitreoretinal surgery. OVDs can be used to separate tissues and create space, to break adhesions, to allow space for surgical manipulation, and to contain hemorrhage by dampening capillary oozing. We focus on the principles and clinical results of several viscosurgery techniques, such as viscodissection and viscodelamination for the management of proliferative vitreoretinopathy and diabetic retinopathy and suprachoroidal buckling for primary retinal detachment. Furthermore, we analyze the techniques in which OVDs served as adjuvants in macular hole surgery, particularly in the handling of the internal limiting membrane, and as volumetric substances against hypotony. Finally, we analyze recent perspectives on vitreous humor biochemical features. Preclinical research led to the belief that hyaluronic acid-based hydrogels could become ideal vitreous substitutes, thanks to their viscoelasticity, porosity, optical properties, and biocompatibility; however, although promising, long-term toxicity issues have limited studies on human subjects.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 713-724"},"PeriodicalIF":5.1,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacological associations of central serous chorioretinopathy: Looking beyond corticosteroids","authors":"Manish Jain , Arthi Mohankumar , Jairo Torres , Hamad A. Alkorbi","doi":"10.1016/j.survophthal.2025.01.017","DOIUrl":"10.1016/j.survophthal.2025.01.017","url":null,"abstract":"<div><div>Central serous chorioretinopathy (CSCR) has multiple associations and risk factors. Of these, psychological stress, corticosteroid treatment, and specific personality traits are well recognized. Other drugs, such as sympathomimetic agents, psychotropic drugs and phosphodiesterase inhibitors, are frequently incriminated. Male preponderance and higher incidence among pregnant and menopausal women give credence to a role of gonadal hormones; however, the acceptance or rejection of the proposed role of other drugs remains challenging due to paucity of data resulting from low usage. Despite presence of multiple risk factors in several patients, a large proportion remains idiopathic. We reviewed all such drugs, including sympathomimetic drugs, psychotropic drugs and recreational agents, phosphodiesterase inhibitors, gonadal hormones and analogues, vasopressin, minoxidil, follistatin, fingolimod, topiramate, muscle relaxants, and vaccines. The mechanisms and adverse event profile of these drugs suggest multiple ways such as alteration of hypothalamic-pituitary-adrenal axis, cortisol surge, activation of sympathetic nervous system, nitric-oxide synthetase, proinflammatory cytokines, complement factor F, Cytochrome P450 3A4, voltage gated ion channels, connexins and neurotransmitters that eventually contribute to CSCR. A common denominator, however, is the systemic and choroidal hemodynamic changes. A detailed medication history can unravel the modifiable risk factors in idiopathic CSCR; this history must include drugs that alter the clearance of other drugs and hormones via the cytochrome P450–3A4 system.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 616-632"},"PeriodicalIF":5.1,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ocular-induced abnormal head postures: A systematic review and analysis","authors":"Saja Al-Dabet, Sherzod Turaev, Nazar Zaki","doi":"10.1016/j.survophthal.2025.01.016","DOIUrl":"10.1016/j.survophthal.2025.01.016","url":null,"abstract":"<div><div>Abnormal head postures (AHPs) are frequently adopted as compensatory mechanisms by individuals affected by various ocular diseases to optimize the utilization of their visual field or alleviate symptoms such as diplopia. We review the causal relationship between ocular diseases and the resulting AHPs. An extensive literature search was conducted to identify and summarize relevant medical studies providing evidence of AHPs in patients diagnosed with conditions like Duane retraction syndrome, Brown syndrome, superior oblique palsy, and other ocular disorders. The analysis explores the proportion of AHP types (head tilt, turn, chin-up/down) and the frequency distribution of ocular conditions for each studied disease. In addition, the degrees of ocular misalignment (hypertropia, hypotropia, esotropia, exotropia) associated with specific AHP manifestations are quantified. Key properties of ocular misalignment and AHPs across different diseases are examined, and Cramer's V statistical measure is employed to assess the association between diseases, AHPs, and ocular misalignment. The findings highlight the need for comprehensive datasets encompassing diverse ocular diseases to support the development of robust artificial intelligence models capable of accurately diagnosing AHPs. This study contributes an in-depth understanding of the mechanisms underlying AHPs and provides a foundation for advancing diagnostic and rehabilitation strategies in vision sciences.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 771-816"},"PeriodicalIF":5.1,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hatem A. Tawfik MD, Mohammad Javed Ali MD, PhD, FRCS
{"title":"Reply: A major review on punctal stenosis: Updated anatomy, epidemiology, etiopathology, and clinical presentation","authors":"Hatem A. Tawfik MD, Mohammad Javed Ali MD, PhD, FRCS","doi":"10.1016/j.survophthal.2025.01.014","DOIUrl":"10.1016/j.survophthal.2025.01.014","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 3","pages":"Page 594"},"PeriodicalIF":5.1,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charles Zhang , Daniel Lai , Daniel Zhu , Charles Palka , Andrew Reynolds , Nicolas Yannuzzi
{"title":"Chlorhexidine for ocular antisepsis before intravitreal injection: A systematic review and meta-analysis","authors":"Charles Zhang , Daniel Lai , Daniel Zhu , Charles Palka , Andrew Reynolds , Nicolas Yannuzzi","doi":"10.1016/j.survophthal.2025.01.013","DOIUrl":"10.1016/j.survophthal.2025.01.013","url":null,"abstract":"<div><div>Povidone-iodine (PI) is the gold standard for pre-intravitreal injection ocular antisepsis. Chlorhexidine (CHX) is an emerging alternative with less ocular irritation. This meta-analysis aims to evaluate post-injection endophthalmitis rates with the use of CHX compared to PI. A systematic search of PubMed, Embase, and Scopus was performed for studies published between January 1, 2000 and February 21, 2024. Data on the number of injections and endophthalmitis cases were analyzed. A sample-size weighted mean difference (MD) meta-analysis was performed using RevMan 5.4.1, p < 0.05 was considered statistically significant. Five studies including 230,656 injections were pooled to determine an endophthalmitis rate of 0.0003 [95 % CI, 0.0001–0.0005] with preinjection CHX antisepsis. Three studies included an additional PI branch and thus were used for secondary meta-analysis comparing CHX against PI. The analysis consisted of 185,799 injections in the CHX group and 269,441 injections in the PI group. No significant difference in the weighted relative risk of endophthalmitis with CHX was found (RR = 1.27 [95 %CI 0.50–3.22], p = 0.62). A total of 24 and 31 cases of culture-positivity were recorded in the CHX and PI groups respectively but no significant difference in weighted means was found (RR = 1.42[95 %CI 0.96–2.12], p = 0.08). This meta-analysis disclosed that the rate of post-IVI endophthalmitis while using CHX antisepsis is approximately 1 in 3937 injections, compared to 1 in 3906 with PI. CHX was not associated with a significant difference in the rate of endophthalmitis or culture-positivity compared to PI.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 676-684"},"PeriodicalIF":5.1,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mateus Pimenta Arruda , Sara Hira , Rian Vilar Lima , Larissa Irigoyen Teixeira Barbosa , Mariana Tosato Zinher , Lubna Al-Sharif , João Lucas de Magalhães Leal Moreira , Giulia Steuernagel Del Valle
{"title":"Pharmacological therapy for relieving pain in panretinal photocoagulation: A network meta-analysis of randomized controlled trials","authors":"Mateus Pimenta Arruda , Sara Hira , Rian Vilar Lima , Larissa Irigoyen Teixeira Barbosa , Mariana Tosato Zinher , Lubna Al-Sharif , João Lucas de Magalhães Leal Moreira , Giulia Steuernagel Del Valle","doi":"10.1016/j.survophthal.2025.01.018","DOIUrl":"10.1016/j.survophthal.2025.01.018","url":null,"abstract":"<div><div>A Bayesian network meta-analysis (NMA) can help compare the various types of analgesics and anesthetics used for lowering pain of panretinal photocoagulation. We carried out a systematic review and network meta-analysis to assess pharmacological interventions for relieving pain in patients undergoing panretinal photocoagulation (PRP). We included 15 randomized controlled trials and 4 crossover trials with a total of 1787 eyes and 45.83 % of the participants were female. The mean age of the participants was 55 years. 2 % peribulbar lidocaine was the only significant treatment compared to placebo (MD −2.4 (95 % CrI −4.7 to −0.20). The rank probability and SUCRA also revealed 2 % peribulbar lidocaine (0.887) as the best treatment in terms of lowering the pain scores followed by etoricoxib (0.809) and potassium diclofenac (0.727). Two per cent peribulbar lidocaine is effective for reducing procedural pain in laser treatment compared to systemic and topical medications. Future studies should evaluate drugs that can reach and act on the posterior segment of the eye.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 645-652"},"PeriodicalIF":5.1,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Cifuentes-González , Yong Le Tong , Germán Mejía-Salgado , Reo Chan , Cheong Fu Yuan Walter , William Rojas-Carabali , Ikhwanuliman Putera , Azadeh Mobasserian , Rina La Distia Nora , Jyotirmay Biswas , Sapna Gangaputra , Jose S. Pulido , John H. Kempen , Quan Dong Nguyen , Alejandra de-la-Torre , Vishali Gupta , James T. Rosenbaum , Rupesh Agrawal , on behalf of REVISE-IUSG study group
{"title":"Global demographic and etiological variations of retinal vasculitis: A systematic review and meta-analysis: International Uveitis Study Group (IUSG) Retinal Vasculitis Study (ReViSe) Report 1","authors":"Carlos Cifuentes-González , Yong Le Tong , Germán Mejía-Salgado , Reo Chan , Cheong Fu Yuan Walter , William Rojas-Carabali , Ikhwanuliman Putera , Azadeh Mobasserian , Rina La Distia Nora , Jyotirmay Biswas , Sapna Gangaputra , Jose S. Pulido , John H. Kempen , Quan Dong Nguyen , Alejandra de-la-Torre , Vishali Gupta , James T. Rosenbaum , Rupesh Agrawal , on behalf of REVISE-IUSG study group","doi":"10.1016/j.survophthal.2025.01.012","DOIUrl":"10.1016/j.survophthal.2025.01.012","url":null,"abstract":"<div><div>This systematic review with meta-analysis explores the global demographic and etiological variations of retinal vasculitis (RV), focusing on differences in frequency, age, sex, and etiology across diverse geographic populations. RV is an inflammatory condition that can lead to visual impairment, making understanding its variations essential for targeted screening and management. Systematic searches were conducted in multiple databases up to February, 2023, following PRISMA guidelines. We included studies with at least 10 RV cases, such that a frequency measurement can be estimated, without restrictions on publication date or language. RV was categorized as Idiopathic RV in the absence of additional ocular or systemic disease, Syndromic RV for ocular involvement without systemic disease, and Secondary RV in those asssociated with systemic disease. The risk of bias was evaluated using standardized tools. A total of 95 studies, including 23,180 patients, were analyzed. The overall RV frequency among uveitis cohorts was 17 %, with European populations showing the highest frequency at 25 %. Idiopathic RV accounted for 1 % of uveitis cohorts and 38 % of RV cohorts, with significant differences across continents. Behçet disease had the highest RV frequency at 56 %. The median age of diagnosis was 33.5 years, and RV was more frequent in males (57 %). Our findings underscore the considerable geographic and demographic variability in RV, particularly in Idiopathic RV, tuberculosis-related RV, and Behçet disease, highlighting the need for tailored, region-specific, and gender-specific approaches to RV diagnosis and treatment.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 756-770"},"PeriodicalIF":5.1,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}