Survey of ophthalmology最新文献

{"title":"Ocular-induced abnormal head postures: A systematic review and analysis","authors":"Saja Al-Dabet,&nbsp;Sherzod Turaev,&nbsp;Nazar Zaki","doi":"10.1016/j.survophthal.2025.01.016","DOIUrl":"10.1016/j.survophthal.2025.01.016","url":null,"abstract":"<div><div>Abnormal head postures (AHPs) are frequently adopted as compensatory mechanisms by individuals affected by various ocular diseases to optimize the utilization of their visual field or alleviate symptoms such as diplopia. We review the causal relationship between ocular diseases and the resulting AHPs. An extensive literature search was conducted to identify and summarize relevant medical studies providing evidence of AHPs in patients diagnosed with conditions like Duane retraction syndrome, Brown syndrome, superior oblique palsy, and other ocular disorders. The analysis explores the proportion of AHP types (head tilt, turn, chin-up/down) and the frequency distribution of ocular conditions for each studied disease. In addition, the degrees of ocular misalignment (hypertropia, hypotropia, esotropia, exotropia) associated with specific AHP manifestations are quantified. Key properties of ocular misalignment and AHPs across different diseases are examined, and Cramer's V statistical measure is employed to assess the association between diseases, AHPs, and ocular misalignment. The findings highlight the need for comprehensive datasets encompassing diverse ocular diseases to support the development of robust artificial intelligence models capable of accurately diagnosing AHPs. This study contributes an in-depth understanding of the mechanisms underlying AHPs and provides a foundation for advancing diagnostic and rehabilitation strategies in vision sciences.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 771-816"},"PeriodicalIF":5.1,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: A major review on punctal stenosis: Updated anatomy, epidemiology, etiopathology, and clinical presentation","authors":"Hatem A. Tawfik MD,&nbsp;Mohammad Javed Ali MD, PhD, FRCS","doi":"10.1016/j.survophthal.2025.01.014","DOIUrl":"10.1016/j.survophthal.2025.01.014","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 3","pages":"Page 594"},"PeriodicalIF":5.1,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chlorhexidine for ocular antisepsis before intravitreal injection: A systematic review and meta-analysis","authors":"Charles Zhang ,&nbsp;Daniel Lai ,&nbsp;Daniel Zhu ,&nbsp;Charles Palka ,&nbsp;Andrew Reynolds ,&nbsp;Nicolas Yannuzzi","doi":"10.1016/j.survophthal.2025.01.013","DOIUrl":"10.1016/j.survophthal.2025.01.013","url":null,"abstract":"<div><div>Povidone-iodine (PI) is the gold standard for pre-intravitreal injection ocular antisepsis. Chlorhexidine (CHX) is an emerging alternative with less ocular irritation. This meta-analysis aims to evaluate post-injection endophthalmitis rates with the use of CHX compared to PI. A systematic search of PubMed, Embase, and Scopus was performed for studies published between January 1, 2000 and February 21, 2024. Data on the number of injections and endophthalmitis cases were analyzed. A sample-size weighted mean difference (MD) meta-analysis was performed using RevMan 5.4.1, p &lt; 0.05 was considered statistically significant. Five studies including 230,656 injections were pooled to determine an endophthalmitis rate of 0.0003 [95 % CI, 0.0001–0.0005] with preinjection CHX antisepsis. Three studies included an additional PI branch and thus were used for secondary meta-analysis comparing CHX against PI. The analysis consisted of 185,799 injections in the CHX group and 269,441 injections in the PI group. No significant difference in the weighted relative risk of endophthalmitis with CHX was found (RR = 1.27 [95 %CI 0.50–3.22], p = 0.62). A total of 24 and 31 cases of culture-positivity were recorded in the CHX and PI groups respectively but no significant difference in weighted means was found (RR = 1.42[95 %CI 0.96–2.12], p = 0.08). This meta-analysis disclosed that the rate of post-IVI endophthalmitis while using CHX antisepsis is approximately 1 in 3937 injections, compared to 1 in 3906 with PI. CHX was not associated with a significant difference in the rate of endophthalmitis or culture-positivity compared to PI.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 676-684"},"PeriodicalIF":5.1,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological therapy for relieving pain in panretinal photocoagulation: A network meta-analysis of randomized controlled trials","authors":"Mateus Pimenta Arruda ,&nbsp;Sara Hira ,&nbsp;Rian Vilar Lima ,&nbsp;Larissa Irigoyen Teixeira Barbosa ,&nbsp;Mariana Tosato Zinher ,&nbsp;Lubna Al-Sharif ,&nbsp;João Lucas de Magalhães Leal Moreira ,&nbsp;Giulia Steuernagel Del Valle","doi":"10.1016/j.survophthal.2025.01.018","DOIUrl":"10.1016/j.survophthal.2025.01.018","url":null,"abstract":"<div><div>A Bayesian network meta-analysis (NMA) can help compare the various types of analgesics and anesthetics used for lowering pain of panretinal photocoagulation. We carried out a systematic review and network meta-analysis to assess pharmacological interventions for relieving pain in patients undergoing panretinal photocoagulation (PRP). We included 15 randomized controlled trials and 4 crossover trials with a total of 1787 eyes and 45.83 % of the participants were female. The mean age of the participants was 55 years. 2 % peribulbar lidocaine was the only significant treatment compared to placebo (MD −2.4 (95 % CrI −4.7 to −0.20). The rank probability and SUCRA also revealed 2 % peribulbar lidocaine (0.887) as the best treatment in terms of lowering the pain scores followed by etoricoxib (0.809) and potassium diclofenac (0.727). Two per cent peribulbar lidocaine is effective for reducing procedural pain in laser treatment compared to systemic and topical medications. Future studies should evaluate drugs that can reach and act on the posterior segment of the eye.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 645-652"},"PeriodicalIF":5.1,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global demographic and etiological variations of retinal vasculitis: A systematic review and meta-analysis: International Uveitis Study Group (IUSG) Retinal Vasculitis Study (ReViSe) Report 1","authors":"Carlos Cifuentes-González ,&nbsp;Yong Le Tong ,&nbsp;Germán Mejía-Salgado ,&nbsp;Reo Chan ,&nbsp;Cheong Fu Yuan Walter ,&nbsp;William Rojas-Carabali ,&nbsp;Ikhwanuliman Putera ,&nbsp;Azadeh Mobasserian ,&nbsp;Rina La Distia Nora ,&nbsp;Jyotirmay Biswas ,&nbsp;Sapna Gangaputra ,&nbsp;Jose S. Pulido ,&nbsp;John H. Kempen ,&nbsp;Quan Dong Nguyen ,&nbsp;Alejandra de-la-Torre ,&nbsp;Vishali Gupta ,&nbsp;James T. Rosenbaum ,&nbsp;Rupesh Agrawal ,&nbsp;on behalf of REVISE-IUSG study group","doi":"10.1016/j.survophthal.2025.01.012","DOIUrl":"10.1016/j.survophthal.2025.01.012","url":null,"abstract":"<div><div>This systematic review with meta-analysis explores the global demographic and etiological variations of retinal vasculitis (RV), focusing on differences in frequency, age, sex, and etiology across diverse geographic populations. RV is an inflammatory condition that can lead to visual impairment, making understanding its variations essential for targeted screening and management. Systematic searches were conducted in multiple databases up to February, 2023, following PRISMA guidelines. We included studies with at least 10 RV cases, such that a frequency measurement can be estimated, without restrictions on publication date or language. RV was categorized as Idiopathic RV in the absence of additional ocular or systemic disease, Syndromic RV for ocular involvement without systemic disease, and Secondary RV in those asssociated with systemic disease. The risk of bias was evaluated using standardized tools. A total of 95 studies, including 23,180 patients, were analyzed. The overall RV frequency among uveitis cohorts was 17 %, with European populations showing the highest frequency at 25 %. Idiopathic RV accounted for 1 % of uveitis cohorts and 38 % of RV cohorts, with significant differences across continents. Behçet disease had the highest RV frequency at 56 %. The median age of diagnosis was 33.5 years, and RV was more frequent in males (57 %). Our findings underscore the considerable geographic and demographic variability in RV, particularly in Idiopathic RV, tuberculosis-related RV, and Behçet disease, highlighting the need for tailored, region-specific, and gender-specific approaches to RV diagnosis and treatment.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 756-770"},"PeriodicalIF":5.1,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correspondence regarding the article: A major review of punctal stenosis: Updated anatomy, epidemiology, etiology, and clinical presentation","authors":"Mostafa M. Diab","doi":"10.1016/j.survophthal.2025.01.015","DOIUrl":"10.1016/j.survophthal.2025.01.015","url":null,"abstract":"","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 3","pages":"Page 593"},"PeriodicalIF":5.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical features, diagnosis, management, and prognosis of circumscribed choroidal hemangioma","authors":"Zuyi Yang ,&nbsp;Dianzhe Tian ,&nbsp;Zhixuan Xie ,&nbsp;Tiantian Cheng ,&nbsp;Youxin Chen ,&nbsp;Xinyu Zhao","doi":"10.1016/j.survophthal.2025.01.001","DOIUrl":"10.1016/j.survophthal.2025.01.001","url":null,"abstract":"&lt;div&gt;&lt;div&gt;Because of its benign nature and rarity, circumscribed choroidal hemangioma (CCH) often receives limited attention, leading to a high rate of misdiagnosis and a lack of standardized treatment protocols. We provide a thorough clarification of the demographics, clinical features, diagnosis, management, and prognosis of CCH. We conducted a systematic search of the PubMed, EMBASE, and Ovid databases up to December, 2023, to identify relevant studies. The study included 106 studies encompassing 3854 patients with CCH. The demographic profile revealed a male preponderance (62 %, 95 % CI 61–64 %) and a peak incidence in the working-age population (30–50 years, 48 %, 95 % CI 39–57 %), with the right eye being involved in 50 % of cases (95 % CI 48–53 %). Clinically, the most common symptom was decreased vision (90 %, 95 % CI 78–99 %), followed by blurred vision, visual field defect, and metamorphopsia. Fundus examination frequently revealed an orange-colored tumor (80 %, 95 % CI 58–96 %) located subfoveally (48 %, 95 % CI 42–53 %), often accompanied by subretinal fluid (SRF) (84 %, 95 % CI 78–89 %) and sometimes exudative retinal detachment (69 %, 95 % CI 51–85 %). The proportion of correctly diagnosed CCH upon first presentation was 13 % (95 % CI 3–26 %), with CCH commonly misdiagnosed as unspecified choroidal tumors, choroidal metastasis, and central serous chorioretinopathy. Photodynamic therapy (PDT) was the most widely researched treatment, taking up 18 % (95 % CI 8–31 %), followed by observation, transpupillary thermotherapy (TTT), and laser photocoagulation. When no treatment was applied, 33 % of patients experienced visual acuity improvement, which increased to 76 % (95 % CI 58–90 %) with radiotherapy and 58 % (95 % CI 50–67 %) with PDT. In terms of tumor shrinkage, radiotherapy was most effective (100 %), with PDT close behind (95 % CI 96–100 %), and TTT at 63 % (95 % CI 45–80 %). PDT led to SRF resolution in 89 % (95 % CI 77–97 %) of patients and cystoid macular edema (CME) resolution in 73 % (95 % CI 38–97 %), while radiotherapy achieved the highest efficacy with 100 % SRF resolution (95 % CI: 99–100 %) and 100 % CME resolution (95 % CI: 83–100 %). Complication rates were highest with radiotherapy (14 %, 95 % CI 5–25 %) and PDT (9 %, 95 % CI 4–16 %). First-line treatment failure rates were highest for TTT (71 %, 95 % CI 44–92 %) and laser (70 %, 95 % CI 28–99 %), with radiotherapy showing the lowest rate (0 %, 95 % CI 0–2 %). Recurrence rates were highest for laser (68 %, 95 % CI 17–100 %) and TTT (62 %, 95 % CI 26–93 %), whereas radiotherapy had the lowest recurrence rate (0 %, 95 % CI 0–1 %). CCH predominantly affects the working-age male population, often leading to vision impairment and SRF. The diagnosis of CCH remains challenging, with low accuracy and frequent misdiagnoses. While PDT is the most widely researched treatment, radiotherapy offers superior outcomes in visual acuity, tumor shrinkage, and resolution of SRF and CME, t","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 3","pages":"Pages 389-400"},"PeriodicalIF":5.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143041425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An update on ocular effects of antidiabetic medications","authors":"Elham Sadeghi ,&nbsp;Elham Rahmanipour ,&nbsp;Nicola Valsecchi ,&nbsp;Saloni Kapoor ,&nbsp;Maria Vittoria Cicinelli ,&nbsp;Jay Chhablani","doi":"10.1016/j.survophthal.2025.01.010","DOIUrl":"10.1016/j.survophthal.2025.01.010","url":null,"abstract":"<div><div>The global increase in the prevalence of type 2 diabetes has led to the development and implementation of new classes of antidiabetic medications, introducing advanced therapeutic options for the management of the disease. These new medications, though primarily designed to regulate blood glucose levels, also have applications in weight management, potentially transforming the current approaches to diabetes treatment. Newer medications, however, have ophthalmic side effects with controversies in trials and real-life data. We comprehensively assessed the ocular benefits and adverse effects of traditional and newer-generation anti-diabetic drugs. Our primary focus is on how these newer medications affect the stage of diabetic retinopathy. Additionally, we explore the associations between these medications and other ocular conditions, including age-related macular degeneration, glaucoma, orbital conditions, and diseases impacting the ocular surface. Furthermore, we provide contextual background by discussing the ocular effects of traditional anti-diabetic drugs.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 4","pages":"Pages 704-712"},"PeriodicalIF":5.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143041424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical and functional changes after internal limiting membrane peeling","authors":"Elham Sadeghi ,&nbsp;Maria F. Colorado-Zavala ,&nbsp;Hussein Almuhtaseb ,&nbsp;Ramesh Venkatesh ,&nbsp;Barbara Parolini ,&nbsp;Jay Chhablani","doi":"10.1016/j.survophthal.2025.01.008","DOIUrl":"10.1016/j.survophthal.2025.01.008","url":null,"abstract":"<div><div>Internal limiting membrane (ILM) peeling has been an acceptable step in vitrectomy surgeries for various retinal diseases such as macular hole, chronic macular edema following epiretinal membrane (ERM), and vitreoretinal traction. Despite all the benefits, this procedure has some side effects, which may lead to structural damage and functional vision loss. Light and dye toxicity may induce reversible and irreversible retina damage, which will be observed in postoperative optical coherence tomography scans. Retinal nerve fiber layer damage is attributed to ganglion cell degeneration and axonal transport alteration and dissociated optic nerve fiber layer is due to Müller cell damage. Eccentric MHs and recurrence of previous MHs may also lead to vision loss. Iatrogenic retinal damage may cause structural retinal changes without significant vision loss or progression to choroidal neovascularization. The mechanism of persistent macular edema after membrane peeling is still unclear, but it has been related to tractional trauma and blood-retina barrier damage. The reappearance of ERM is another cause of decreased vision after ILM peeling, which might be secondary to incomplete membrane removal. In glaucoma patients, ILM peeling is associated with significantly worsening the mean deviation on the visual field test after the surgery. We discussed various causes of vision loss and structural changes following ILM peeling. These causes may be attributed to the surgical procedure itself or the associated steps, instruments, and dyes used during the ILM peeling procedure.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 3","pages":"Pages 357-368"},"PeriodicalIF":5.1,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive review of structure-function correlations in age-related macular degeneration: Contributions of microperimetry","authors":"Cristina Ţurcaş ,&nbsp;Simona Delia Nicoară","doi":"10.1016/j.survophthal.2025.01.009","DOIUrl":"10.1016/j.survophthal.2025.01.009","url":null,"abstract":"<div><div>Age-related macular degeneration (AMD) is a leading cause of visual impairment and irreversible blindness worldwide. High-resolution imaging techniques have been pivotal in characterizing the morphological alterations in the retina and in identifying structural biomarkers with prognostic significance. In clinical practice, visual function is primarily assessed through visual acuity testing, which, however, does not completely reflect the functional deficits experienced by patients. Microperimetry provides a more comprehensive evaluation of macular function, enabling a direct correlation with retinal structure. We examine the current literature on the correlation between morphological biomarkers – identified via optical coherence tomography, optical coherence tomography angiography, and fundus autofluorescence – and retinal sensitivity, as assessed by microperimetry. By encompassing all stages of AMD, we explore the association between retinal sensitivity and a broad spectrum of structural parameters, including distinct drusen phenotypes, hyperreflective foci, the integrity and thickness of various retinal layers, the junctional zone of geographic atrophy, exudative features of neovascular AMD, choriocapillaris flow deficits, and diverse patterns of autofluorescence, among numerous other relevant structural markers. By offering a deeper understanding of the structure-function correlations in disease progression, we provide critical up-to-date insights into the underlying mechanisms of AMD. Moreover, as novel therapeutic strategies continue to emerge, these correlations may serve as more robust endpoints for future clinical trials.</div></div>","PeriodicalId":22102,"journal":{"name":"Survey of ophthalmology","volume":"70 3","pages":"Pages 426-450"},"PeriodicalIF":5.1,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}