Sultan Qaboos University Medical Journal最新文献_第7页

Nurturing the Future: Understanding maternal knowledge of child development in Oman. 培育未来：了解阿曼母亲对儿童发展的了解。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2845

Watfa Al-Mamari, Ahmed B Idris, Saquib Jalees, Muna Al-Jabri, Mohammed A Mirghani, Dina Al Khalili, Asila Al Yarubi, Jamana Al Zadjali, Zahra Al Lawati, Ayat Al Lawati, Ahmed Al Saidi, Kamila Al Alawi, Sathiya Murthi, Wafa S Al-Maamari

{"title":"Nurturing the Future: Understanding maternal knowledge of child development in Oman.","authors":"Watfa Al-Mamari, Ahmed B Idris, Saquib Jalees, Muna Al-Jabri, Mohammed A Mirghani, Dina Al Khalili, Asila Al Yarubi, Jamana Al Zadjali, Zahra Al Lawati, Ayat Al Lawati, Ahmed Al Saidi, Kamila Al Alawi, Sathiya Murthi, Wafa S Al-Maamari","doi":"10.18295/2075-0528.2845","DOIUrl":"10.18295/2075-0528.2845","url":null,"abstract":"Objectives: This study aimed to examine the knowledge of Omani women of childbearing age concerning infant developmental care.Methods: This cross-sectional study included 1,006 Omani women of childbearing age, recruited from outpatient clinics at Sultan Qaboos University Hospital (response rate = 71%). Their knowledge was evaluated using the Knowledge of Infant Development Inventory (KIDI), a validated self-report questionnaire. The KIDI scores were analysed to identify associations with demographic variables such as women's age, education level, employment status and number of children. Data were collected from June 2023 to October 2023.Results: The mean age of the participating women was 31.6 ± 8.4 years. The majority were from Muscat (49.6%), with over half holding bachelor's degrees (57.1%) and 39% being employed. The mean correct response rate for KIDI was 0.63 ± 0.11, suggesting that, on average, the women answered 63% of the questions accurately. Higher education levels and employment status were significantly associated with better knowledge scores (P < 0.001). Misconceptions were prevalent in areas such as infant sensory capabilities and developmental milestones.Conclusions: The findings reveal significant gaps in knowledge regarding child development among Omani women, particularly those with lower levels of educational attainment. Targeted educational interventions are needed to enhance maternal knowledge and support child development in Oman.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"352-362"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psoriasis Presenting as Koebner Phenomena. 银屑病表现为Koebner现象。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2844

Zamzam Al Qutaiti, Ayida Al Khalili, Asem Shalaby

引用次数: 0

Utility of Carboxyhemoglobin Level for the Diagnosis of Invasive Bacterial Infection in a Febrile Neonate at Paediatric Emergency Department. 碳氧血红蛋白水平在儿科急诊科发热新生儿侵袭性细菌感染诊断中的应用。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2867

Abdulhamid Al Hinai, Laila Al Yazidi, Sanjay Jaju, Nasser Al Sidairi, Khalil Al Habsi, Mohammed Al Lawati, Saeed Al Obeidani

{"title":"Utility of Carboxyhemoglobin Level for the Diagnosis of Invasive Bacterial Infection in a Febrile Neonate at Paediatric Emergency Department.","authors":"Abdulhamid Al Hinai, Laila Al Yazidi, Sanjay Jaju, Nasser Al Sidairi, Khalil Al Habsi, Mohammed Al Lawati, Saeed Al Obeidani","doi":"10.18295/2075-0528.2867","DOIUrl":"10.18295/2075-0528.2867","url":null,"abstract":"Objective: Carboxyhaemoglobin (COHb), which represents the fraction of carbon monoxide bound to haemoglobin, is available as a point-of-care test in the emergency department. This study aimed to assess the role of COHb in the diagnosis of invasive bacterial infections (IBI) in a paediatric emergency department.Methods: This retrospective study examined a single reading of venous COHb values in otherwise healthy neonates who presented with febrile illness at the paediatric emergency department at Royal Hospital, Muscat, Oman, between December 2019 and December 2022. The optimal COHb level for the diagnosis of IBI was determined using receiver operating characteristic curve analysis. Multivariate regression analysis was applied to assess the effect of age, birth weight and sex as cofounders for the diagnosis.Results: A total of 336 neonates presented to the paediatric emergency department with febrile illnesses and 201 neonates met the inclusion criteria; 43 neonates were culture-confirmed to have IBI. A COHb level ≥1.4% carries a sensitivity of 74% and a specificity of 69% for the diagnosis of IBI. Moreover, it was strongly independent of the diagnosis when adjusted for the confounding factors of birth weight, sex, pediatric early warning score, type of admission and gestational age (odds ratio = 6.080, 95% confidence interval: 2.810-13.155; P <0.001).Conclusion: This is the first study to examine COHb as a biomarker for IBI in a pediatric emergency setting. COHb may be a useful biochemical marker for risk stratification in febrile neonates. Further studies are required to better delineate its clinical utility.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"531-538"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IL-6 Induces CD45 Expression on Myeloid Cells. IL-6诱导骨髓细胞CD45表达

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2872

Maryam Ahmed Al Barashdi, Ahlam Ali, Mary Frances McMullin, Ken Mills

{"title":"IL-6 Induces CD45 Expression on Myeloid Cells.","authors":"Maryam Ahmed Al Barashdi, Ahlam Ali, Mary Frances McMullin, Ken Mills","doi":"10.18295/2075-0528.2872","DOIUrl":"10.18295/2075-0528.2872","url":null,"abstract":"Objectives: Activation of IL-6 facilitates CD45 expression in myeloma cells, but little has been reported for myeloid malignancies. This study aimed to investigate whether IL-6 enhances CD45 expression on myeloid malignancies and whether myeloid cells are dependent on IL-6 activation to express CD45 on their cell membrane.Methods: This study was conducted from January to March 2022 at the Queen's University Belfast, UK. Myeloid cell lines such as HEL and OCI-AML3 which expressed higher levels of CD45, and UT-7 and the pro-B NALM-6 cell lines that had lower CD45 levels as well as primary cells were used. The correlation between CD45 expression and IL-6 activation in myeloid cells was studied in terms of survival and response to chemotherapy such as cytarabine.Results: It was found that IL-6 enhances cellular survival in myeloid leukaemia cells. Expression of CD45 could be correlated with IL-6 activation in myeloid leukaemia cells. Quantification of IL-6 confirms the significant effect on cellular proliferation. More importantly, IL-6 significantly alters CD45 expressed myeloid leukaemia cellular response to chemotherapy such as cytarabine.Conclusion: IL-6 significantly induced alteration to cytarabine cellular response in those cells of higher CD45 expression, while its effect on cells of lower CD45 expression was minimal. This suggests the importance of CD45 in the activation of IL-6 pathway and initiation of cellular proliferation events with its consequences of cytarabine chemo resistance and enhancement of leukaemia cells survival and proliferation by inhibiting the apoptotic activities of cytarabine.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"552-565"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimising Healthcare Delivery: Efficiency analysis of Oman's governorate hospital networks. 优化医疗保健服务：阿曼省级医院网络的效率分析。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2874

Sultana M Al-Sabahi, Avinash D Pinto, Qasem Al-Salmi, Hilal A Al-Sabti

{"title":"Optimising Healthcare Delivery: Efficiency analysis of Oman's governorate hospital networks.","authors":"Sultana M Al-Sabahi, Avinash D Pinto, Qasem Al-Salmi, Hilal A Al-Sabti","doi":"10.18295/2075-0528.2874","DOIUrl":"10.18295/2075-0528.2874","url":null,"abstract":"Objectives: This study aimed to evaluate the efficiency of the healthcare facilities in the Oman to guide the decision-making process and benchmarking.Methods: Input-oriented data envelopment analysis (DEA) was used to assess the relative efficiency of governorate hospitals in Oman using 2022 data extracted in December 2023. In the second stage of data analysis, the Tobit model was applied to assess determinants of governorate hospital inefficiency; 3 DEA models were created (staffing, structure and budget).Results: A total of 10 governorate hospitals were included in this study. The efficiency score change was small for the governorate hospitals and no hospital shifted from full efficiency to very low efficiency between the 3 models. The only explanatory variables that are significantly correlated with efficiency score in the structure model were bed occupancy rate (P = 0.007, 95% confidence interval [CI]: 0.010 to 0.037) and nurse-to-bed ratio (P = 0.099, 95% CI: -1.219 to 0.146). The results of the Tobit regression for the staffing model of DEA show that there are 3 variables which are positively correlated to efficiency score: bed occupancy rate, nurse-to-bed ratio and expenditure. The third model evaluated efficiency by comparing resource utilisation to service outputs, identifying 6 fully efficient hospitals and opportunities for enhancing resource allocation.Conclusions: These results allow for benchmarking against best-performing hospitals, facilitating the identification of areas for sustained improvement. Reallocating resources from overperforming to underperforming hospitals, streamlining workflows and implementing a continuous performance evaluation system can help bridge efficiency gaps.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"566-572"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Al Muhalab Bin Aby Sufra Hall, Ibri, Oman, 16 September 2024. 2024年9月16日，阿曼伊布里的Al Muhalab Bin Aby Sufra大厅。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2862

引用次数: 0

Chondromyxoid Fibroma of Phalanges. 指骨软骨粘液样纤维瘤。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/squmj.10.2024.068

Lubna S Khan, Sifa Farheen, Vijay K Pandey, Vinay P Singh, Manoj G Madakshira

引用次数: 0

Effectiveness of Vaginal Magnesium Sulfate on Pain and Labor Duration: A systematic review and meta-analysis. 阴道硫酸镁对疼痛和分娩时间的影响：一项系统回顾和荟萃分析。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2885

Somayeh Makvandi, Elham Manouchehri, Mahdieh Razi, Samaneh A Mofrad, Mona Larki

{"title":"Effectiveness of Vaginal Magnesium Sulfate on Pain and Labor Duration: A systematic review and meta-analysis.","authors":"Somayeh Makvandi, Elham Manouchehri, Mahdieh Razi, Samaneh A Mofrad, Mona Larki","doi":"10.18295/2075-0528.2885","DOIUrl":"10.18295/2075-0528.2885","url":null,"abstract":"This systematic review and meta-analysis aimed to evaluate the effectiveness of vaginal magnesium sulfate (MgSO4) administration during labour. A comprehensive search was conducted across six databases up to 30 July 2024, and updated on 13 January 2025, with no restrictions on time, language, or geographical region. The risk of bias was assessed using the RoB 2 tool, and the certainty of evidence was evaluated using GRADEpro. A total of seven randomised controlled trials were included. The meta-analysis demonstrated that topical magnesium sulfate significantly increased cervical dilatation by 2.27 cm (95% confidence interval [CI]: 1.98 to 2.56; P <0.00001) and cervical effacement by 15.3% (95% CI: 7.79 to 22.82; P <0.0001) two hours after administration, compared to control groups. Furthermore, it shortened the active phase of labour by 1.63 hours (95% CI: -2.15 to -1.11; P <0.00001) and reduced reported pain levels. These findings suggest that vaginal magnesium sulfate may be a promising and easily administered intervention, warranting further investigation in clinical practice.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"697-707"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eczema Coxsackium as an Atypical Presentation of Hand-Foot-Mouth Disease. 柯萨奇湿疹是手足口病的一种非典型表现。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2913

Omar A Ceballos, Mónica Gómez-Manzanares, Víctor H Gónzalez-Vico, Marina Montero-García

引用次数: 0

Network Meta-Analysis of Randomized Controlled Trials Comparing Safety and Efficacy of Pharmacological Treatments in Reducing Pain During Intrauterine Device Insertion. 比较药物治疗减轻宫内节育器插入疼痛的安全性和有效性的随机对照试验的网络荟萃分析。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2900

Ahmed Ashour, Ahmed H Saad, Iman Elzahaby

{"title":"Network Meta-Analysis of Randomized Controlled Trials Comparing Safety and Efficacy of Pharmacological Treatments in Reducing Pain During Intrauterine Device Insertion.","authors":"Ahmed Ashour, Ahmed H Saad, Iman Elzahaby","doi":"10.18295/2075-0528.2900","DOIUrl":"10.18295/2075-0528.2900","url":null,"abstract":"Conflicting evidence exists regarding the effectiveness of pharmacological interventions in reducing pain during intrauterine device (IUD) insertion. This study aimed to evaluate the safety and efficacy of various analgesics and to rank their effectiveness. A total of 71 randomized controlled trials (RCTs) involving 10,870 women were included. Data were sourced from PubMed, Cochrane Library, Scopus, and other databases up to September 2023. Analyses were performed using the Netmeta package in R, with results reported as standardized mean differences (SMDs) and risk ratios (RRs), each with corresponding 95% confidence intervals (CIs). Lidocaine 4% gel (5 mL) emerged as the most effective option for pain relief during IUD insertion (SMD = -4.5; 95% CI: -5.9- -3.0; low-quality evidence), followed by lidocaine 1% solution (10 mL; SMD = -3.20). Lidocaine 4% gel also ranked highest for reducing pain during tenaculum placement, while misoprostol 400 mcg improved the ease of IUD insertion. Despite the low quality of evidence, lidocaine 4% gel appears to be the most effective pharmacological intervention for pain reduction during IUD insertion.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"813-838"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12538906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145347543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0