{"title":"Enhancing Delirium Prediction and Prevention in Elderly Patients Through Machine Learning-Based Analysis.","authors":"Abdullah M Al Alawi, Juhaina S Al Maqbali","doi":"10.18295/2075-0528.2869","DOIUrl":"10.18295/2075-0528.2869","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to identify predictors of delirium within 24 hours of admission in elderly patients using machine learning (ML) models and evaluate their performance.</p><p><strong>Methods: </strong>This prospective cohort study was conducted among patients aged 65 years and older admitted to the general medical unit of Sultan Qaboos University Hospital, Muscat, Oman, from January 2022 to May 2023. Clinical and demographic data were collected and analysed using 4 ML models: logistic regression, random forest, gradient boosting and support vector machine. Model performance was evaluated using accuracy, precision, recall, F1 score and area under the curve-receiver operating characteristic (AUC-ROC) metrics. Cross-validation was performed to assess model robustness and feature importance analysis was conducted to identify key predictors.</p><p><strong>Results: </strong>A total of 327 patients were included in this study. The random forest model demonstrated the best performance, achieving an accuracy of 96.9%, an F1 score of 97.2%, and an AUC-ROC of 98.4%. Cross-validation confirmed the model's stability. Feature importance analysis identified acute kidney injury, respiratory failure, dementia, stroke and decompensated heart failure as the most influential predictors of delirium.</p><p><strong>Conclusion: </strong>ML models, particularly the random forest model, exhibited strong predictive performance in identifying patients at risk of delirium within 24 hours of admission. These findings support the potential of ML in enhancing early delirium detection and guiding targeted preventive strategies. Future research should focus on external validation to confirm the model's applicability across different healthcare settings.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"539-546"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cross-Cultural Comparison of Nomophobia, Netlessphobia and Anxiety among Nursing Students in Iran and Türkiye: <i>A mediation analysis</i>.","authors":"Mohsen S Ardakani, Abdolrahim Asadollahi, Sevil Ç Özbay, Yalçin Kanbay, Maryam Bakhtiar","doi":"10.18295/2075-0528.2901","DOIUrl":"10.18295/2075-0528.2901","url":null,"abstract":"<p><strong>Objectives: </strong>In the digital era, excessive reliance on smartphones and internet access has led to emerging psychological concerns, including nomophobia (fear of being without a mobile phone) and netlessphobia (fear of being without internet), which are increasingly linked to anxiety among students. This study aimed to compare the prevalence and psychological impact of these phobias among nursing students in Iran and Türkiye.</p><p><strong>Methods: </strong>This cross-sectional study was included nursing students; participants completed validated questionnaires assessing nomophobia, netlessphobia and anxiety. Data were collected from June to July 2024 via paper-based and electronic surveys. Statistical analyses included independent t-tests, multiple regression and mediation modeling.</p><p><strong>Results: </strong>A total of 697 nursing students were included (mean age = 21.94 years, 96.4% were single) from in Iran (n = 381) and Türkiye (n = 316). No significant gender differences were found in terms of nomophobia, netlessphobia or anxiety levels in either country. However, Turkish students reported higher netlessphobia (mean = 37.43) than Iranian students, while Iranians showed slightly higher anxiety (mean = 17.32). Both phobias strongly predicted anxiety in both samples (R<sup>2</sup> >0.3, f<sup>2</sup> >0.4). Mediation analysis revealed that 77% of the effect of smartphone overuse on anxiety was indirectly explained by netlessphobia, suggesting anxiety stems more from fear of losing internet access than from phone absence.</p><p><strong>Conclusions: </strong>This study's findings underscore the need for targeted mental health interventions in nursing education, such as digital wellness programmes, mindfulness training and awareness campaigns. Culturally sensitive strategies to promote healthy tech habits could mitigate anxiety related to these phobias in an increasingly connected world.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"720-730"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muna Al Saadoon, Yahya Al Hinai, Alrumaitha A Alsabri, Hajar N S Al Qutaiti, Syed Rizvi
{"title":"Teachers and Caregivers Knowledge and Attitude About Child Rights and Child Protection in Muscat, Oman.","authors":"Muna Al Saadoon, Yahya Al Hinai, Alrumaitha A Alsabri, Hajar N S Al Qutaiti, Syed Rizvi","doi":"10.18295/2075-0528.2859","DOIUrl":"10.18295/2075-0528.2859","url":null,"abstract":"<p><strong>Objectives: </strong>Child abuse and neglect (CAN) is a pervasive public health problem that transcends geographical, religious, economic and ethnic boundaries. It can result in both short- and long-term negative consequences and unhealthy lifestyles among victims. This study aimed to evaluate the awareness and attitudes of teachers and caregivers of Grade 1-4 children regarding child rights and their knowledge of the available child protection services in Oman.</p><p><strong>Methods: </strong>This cross-sectional study examined self-reported knowledge and attitudes regarding child rights and child protection services in the Muscat governorate, Oman, from September to December 2017. Of the 50 eligible schools that offered Grades 1-4, 6 schools were randomly selected. All teachers in the selected schools were invited to participate. Additionally, all caregivers of children from 4 randomly selected classes in each school were invited to participate in the study by completing a questionnaire.</p><p><strong>Results: </strong>A total of 397 caregivers (response rate = 66.2%) and 168 teachers (response rate = 55.7%) completed the questionnaires. Both caregivers and teachers demonstrated a positive attitude towards child rights and child protection. However, their knowledge regarding available child protection services and the existing Omani child law was limited. A significant positive association was found between teacher participation in awareness activities on CAN and the reporting of suspected cases of sexual and physical abuse to the concerned authorities (<i>P</i> = 0.001 and 0.007, respectively).</p><p><strong>Conclusions: </strong>While caregivers and teachers reported a positive attitude towards children's rights, their knowledge regarding child protection services in Oman was limited. It is therefore mandatory to improve and expand teacher training programmes and awareness activities for caregivers to increase their understanding of child protection services. This will increase the utilisation of these services, maximising benefits for the community and providing better protection for affected children.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"465-471"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ola Nasser, Wafaey Gomaa, Wafaa Aref, Rabab Moussa
{"title":"High SPINK1 Immunostaining in Colorectal Carcinoma is Associated with Poor Outcomes.","authors":"Ola Nasser, Wafaey Gomaa, Wafaa Aref, Rabab Moussa","doi":"10.18295/2075-0528.2889","DOIUrl":"10.18295/2075-0528.2889","url":null,"abstract":"<p><strong>Objectives: </strong>Colorectal cancer (CRC) is the third most common cancer worldwide and is the second leading cause of cancer-related deaths. Serine protease inhibitor Kazal-type 1 (SPINK1) is found to be related to poor prognostic criteria and shortened overall survival of some malignancies such as liver, breast, lung, pancreatic and renal cancers. SPINK1 can be a potential biomarker for early detection and prediction of immune checkpoint blockade treatment response. Therefore, this study aimed to examine the possible role of SPINK1 in colorectal carcinogenesis and its prognostic ability.</p><p><strong>Methods: </strong>This study used paraffin blocks of patients diagnosed with colorectal adenoma, primary CRC and available positive lymph node metastases. Specimens were obtained between April 2018 and June 2022 at the Department of Pathology, Faculty of Medicine, Minia University, Egypt. Immunohistochemistry was done for SPINK1 antibody and appropriate statistical analysis of results was performed.</p><p><strong>Results: </strong>A total of 70 archival samples of CRC, 18 of colorectal adenoma and 20 of metastatic lymph nodes were used in this study. In a normal colon, there was a negative to weak SPINK1 immunostaining. High cytoplasmic immunostaining was seen in 57.1% of patients while low immunostaining in 42.9% of CRC. SPINK1 immunostaining was statistically associated with tumour grade (<i>P</i> = 0.024), stage (<i>P</i> <0.001), nodal status (<i>P</i> = 0.010), lymph node ratio (<i>P</i> = 0.044), lymphovascular invasion (<i>P</i> <0.001), tumour necrosis (<i>P</i> <0.001) and tumour infiltrating lymphocytes (<i>P</i> <0.001). No statistically significant association was found between SPINK1 and patient gender, age, tumour site, tumour size, histological subtype, perineural invasion, margin status and adenoma. A statistically significant association was detected between SPINK1 immunostaining in CRC and adenomas (<i>P</i> = 0.019) and between CRC and associated nodal metastasis (<i>P</i> = 0.013).</p><p><strong>Conclusion: </strong>SPINK1 immunostaining is increased in CRC and associated with poor prognostic criteria and is significantly associated with immunoactivity in adenoma and associated nodal metastasis.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"681-688"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maryam Al Riyami, Abdullah Al Alawi, Hajar Al Balushi, Raya Al Ghafri, Hafsa Al Mamari, Jamal Al-Aghbari
{"title":"Pulmonary Embolism in Patients Admitted to Sultan Qaboos University Hospital: <i>A 5-year experience</i>.","authors":"Maryam Al Riyami, Abdullah Al Alawi, Hajar Al Balushi, Raya Al Ghafri, Hafsa Al Mamari, Jamal Al-Aghbari","doi":"10.18295/2075-0528.2890","DOIUrl":"10.18295/2075-0528.2890","url":null,"abstract":"<p><strong>Objectives: </strong>Pulmonary embolism (PE) is a potentially fatal condition among hospitalised patients, with a prevalence of approximately 1.0%. PE is associated with high morbidity and mortality. This study aimed to identify patient characteristics and risk factors related to the development, recurrence, and mortality of PE in hospitalised patients at Sultan Qaboos University Hospital (SQUH), Muscat, Oman.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at SQUH, involving patients diagnosed with PE during admission between January 2015 and December 2019. Data were collected from electronic patient records, including demographic details, comorbidities, risk factors and healthcare outcomes. Pulmonary Embolism Severity Index (PESI) scores were calculated. Statistical analyses were performed to identify predictors of mortality and recurrence of PE.</p><p><strong>Results: </strong>A total of 192 patients diagnosed with PE were included in this study; 16.7% died during the index admission. Older age, higher PESI scores, central venous access and autoimmune disease were significant independent predictors of inpatient mortality. The recurrence rate of PE was 9.5% during the follow-up period, with no significant association between patient characteristics and recurrence. This study also highlighted the prevalence of risk factors such as reduced mobility, recent hospitalisation, obesity and infection among the cohort.</p><p><strong>Conclusion: </strong>This research contributes to the knowledge of PE recurrence, mortality and associated risk factors. Hypertension, diabetes and chronic heart failure are common comorbidities in PE patients. Older age, higher PESI scores, central venous access and autoimmune disease were significant predictors of mortality.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"765-772"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salim Al-Busaidi, Eman Aly, Mohammed Al-Abri, Salim Al-Salmi, Abdullah Al-Hinai, Omar Al-Naqabi, Jawaher Al-Maskari, Marwa Al-Mahroqi, Alaa Hashish, Henry Doctor, Arash Rashidian, Jean Jabbour, Abdullah Al-Alawi
{"title":"Enhancing Mortality Data Accuracy: <i>Outcomes from a collaborative national workshop in Oman</i>.","authors":"Salim Al-Busaidi, Eman Aly, Mohammed Al-Abri, Salim Al-Salmi, Abdullah Al-Hinai, Omar Al-Naqabi, Jawaher Al-Maskari, Marwa Al-Mahroqi, Alaa Hashish, Henry Doctor, Arash Rashidian, Jean Jabbour, Abdullah Al-Alawi","doi":"10.18295/2075-0528.2821","DOIUrl":"10.18295/2075-0528.2821","url":null,"abstract":"<p><strong>Objectives: </strong>Mortality data is essential for global health policy and sustainable development goals, yet errors in death notifications, often exceeding 50%, challenge its accuracy. This is largely due to the lack of formal training among physicians and medical coders in issuing death notifications. This study conducting a national educational intervention and aimed to assess the outcomes of the intervention.</p><p><strong>Methods: </strong>A 2-day workshop was held in Oman in June 2023 for physicians and medical coders, employing a pre- and post-assessment design. The training, developed by both international and national experts, covered aspects of mortality data quality, based on the International Form of Medical Certificate of Cause of Death and validated by the World Health Organization. The curriculum focused on correctly defining and sequencing the causes of death and identifying common certification errors.</p><p><strong>Results: </strong>A total of 39 individuals, including doctors (59%) and medical coders (41%), participated in the workshop. A comparison of pre- and post-workshop assessments revealed significant enhancements in understanding mortality data. The doctors generally outperformed the coders in these improvements. Participant feedback was overwhelmingly positive, with approximately 80% strongly agreeing on the clarity and relevance of the content, as well as the engaging nature of activities and exercises.</p><p><strong>Conclusions: </strong>The intervention significantly improved the quality of mortality data by enhancing the accuracy of death certifications. This success was achieved through a collaborative effort, highlighting the model's potential for future online modules to extend its reach. This study underscores the importance of structured training in enhancing the utility of mortality data, contributing to better health system evaluation and policy-making.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"218-224"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abel T Oommen, Arunodaya R Gujjar, Suad Al-Jahdhami, Abdullah R Al-Asmi, Ali Sajjad
{"title":"Anti-Neutrophil Cytoplasmic Antibody-Associated Central and Peripheral Nervous System Vasculitis.","authors":"Abel T Oommen, Arunodaya R Gujjar, Suad Al-Jahdhami, Abdullah R Al-Asmi, Ali Sajjad","doi":"10.18295/2075-0528.2820","DOIUrl":"10.18295/2075-0528.2820","url":null,"abstract":"<p><p>The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) usually manifests as systemic vasculitis. AAV with central nervous system involvement in the form of mesenrhombencephalitis and peripheral neuropathy is extremely rare. We report a 59-year-old male patient who presented to a tertiary care hospital in Muscat, Oman, in 2024. He had a subacute presentation of altered sensorium, multiple cranial nerve palsy and ataxia with 3 months history of bilateral foot drop. Brain imaging was suggestive of mesenrhombencephalitis with subarachnoid and intraparenchymal haemorrhage. Nerve conduction studies revealed sensorimotor axonal neuropathy. Vasculitis profile showed perinuclear-ANCA positivity and the nerve biopsy was suggestive of vasculitic neuropathy. He was treated with intravenous steroids and maintained on rituximab. His neurological deficits improved with residual bilateral foot drop.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"282-287"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samira Z Sayed, Engy R Mohamed, Mohamed T A Moustafa, Lamia H Ali, Mohamed H Mahgoob
{"title":"Assessing Vascular Biomarkers and Their Association with Hypertension in Paediatric Chronic Kidney Disease.","authors":"Samira Z Sayed, Engy R Mohamed, Mohamed T A Moustafa, Lamia H Ali, Mohamed H Mahgoob","doi":"10.18295/squmj.10.2024.056","DOIUrl":"10.18295/squmj.10.2024.056","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to examine the correlation between children with chronic kidney disease (CKD) and endothelial dysfunction biomarkers, including asymmetric dimethylarginine (ADMA), angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A), as well as blood pressure and cardiovascular risk.</p><p><strong>Methods: </strong>This case-control study included children who were divided into 2 groups: children with CKD at different stages and healthy controls. The study was performed from November 2021 to October 2022 at El-Minia University hospitals and the general outpatient paediatric clinic at Minia University, Minya, Egypt. Blood pressure measurements were taken, and levels of ADMA, Ang-2 and VEGF-A were determined.</p><p><strong>Results: </strong>A total of 90 children divided into 2 groups (45 each) were included in this study. The results showed that children with CKD exhibited significantly higher ADMA, Ang-2 and VEGF-A levels compared to the control group. Both systolic and diastolic blood pressure showed a positive correlation with the elevated biomarkers, while the estimated glomerular filtration rate (e-GFR) demonstrated a negative association.</p><p><strong>Conclusions: </strong>Elevated levels of VEGF-A, Ang-2 and ADMA have been linked to increased cardiovascular risk and antihypertensive treatment in children with CKD. These biomarkers may prove valuable in clinical evaluations to improve therapy and outcomes for children with CKD.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"66-73"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sharjeel Usmani, Khulood Al Riyami, Anjali Jain, Syed Furqan Hashmi, Sofiullah Abubakar, Asiya Al Busaidi
{"title":"Unveiling Hemangiopericytoma: <i>A case demonstrating the utility of somatostatin receptor-positive metastatic hemangiopericytoma on <sup>68</sup>Ga-DOTA TOC PET/CT</i>.","authors":"Sharjeel Usmani, Khulood Al Riyami, Anjali Jain, Syed Furqan Hashmi, Sofiullah Abubakar, Asiya Al Busaidi","doi":"10.18295/2075-0528.2856","DOIUrl":"10.18295/2075-0528.2856","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"450-452"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salim Al-Busaidi, Hatim Al-Lawati, Nasiba Al-Maqrashi, Arunodaya R Gujjar
{"title":"Utility of Routine 24-Hour Electrocardiographic Holter Monitoring for Detecting Atrial Fibrillation in Patients Admitted with Acute Stroke Syndromes.","authors":"Salim Al-Busaidi, Hatim Al-Lawati, Nasiba Al-Maqrashi, Arunodaya R Gujjar","doi":"10.18295/2075-0528.2824","DOIUrl":"10.18295/2075-0528.2824","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess the operating characteristics of standard 12-lead electrocardiogram (ECG) and 24-hour Holter studies in detecting atrial tachyarrhythmia in patients with acute stroke syndromes. The study's objective was to determine the potential factors that increased the likelihood of detecting atrial fibrillation (AF) and its impact on management.</p><p><strong>Methods: </strong>This retrospective cohort study included adults (aged ≥18 years) admitted at Sultan Qaboos University Hospital from January 2010 to December 2019, with ischaemic stroke or transient ischaemic attack and had undergone a 24-hour Holter study. The hospital stroke registry was used to screen patients.</p><p><strong>Results: </strong>A total of 1,258 patients were screened and only 460 patients, who had undergone 521 Holter studies, met the inclusion criteria. Among them, AF was detected with baseline ECG in 20 patients (4.4%), while new AF was detected in only eight patients (1.7%). Significant predictors for increased AF detection by Holter included advanced age, peripheral vascular disease (PVD), left ventricular diastolic dysfunction and chronic kidney disease Stage III, with PVD highlighted as an independent predictor (odds ratio = 17.133, 95% confidence interval = 2.139-137.201, <i>P</i> = 0.007). The degree of agreement between the baseline ECG and Holter ECG was substantial (K = 0.649, <i>P</i> < 0.001). A total of 130 Holter needs to be performed to detect one case of treatable AF.</p><p><strong>Conclusions: </strong>This study showed that a routine ECG Holter study in acute stroke has a low clinical yield in detecting AF, which is in substantial agreement with baseline ECG. Therefore, further investigation of paroxysmal AF in acute stroke should be reserved for high-risk patients.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"191-199"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}