Sultan Qaboos University Medical Journal最新文献_第10页

Surgical Management of Renal Cell Carcinoma 肾细胞癌的手术治疗

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.033

Noor N Junejo, N. AbuDraz, Shahid Aquil, Joseph K Mathew, Ghalib Al Badaai, M. Al-Marhoon, K. M. Siddiqui

{"title":"Surgical Management of Renal Cell Carcinoma","authors":"Noor N Junejo, N. AbuDraz, Shahid Aquil, Joseph K Mathew, Ghalib Al Badaai, M. Al-Marhoon, K. M. Siddiqui","doi":"10.18295/squmj.6.2024.033","DOIUrl":"https://doi.org/10.18295/squmj.6.2024.033","url":null,"abstract":"Objectives: Renal Cell Carcinoma (RCC) is one of the foremost urological malignancies. In Oman, an age-standardized incidence rate of 2.5 per 100,000 per year is reported. There is a trend towards early detection and use of minimally invasive technology for the treatment of RCC. Aim of our study was to report the changing trend in clinical presentation and RCC management, including to compare the outcomes of laparoscopic versus open nephrectomy in Oman. Methods: After ethical committee’s approval, the bio-data for adult patients and peri-operative details were collected, who were diagnosed with RCC between 2011 and 2022. We analyze the variables, both continuous and categorical by Chi-square analysis. The p-value <0.05 was set as a level of significance. Results: Fifty-six patients underwent surgical treatment of RCC. Among them, 34 patients underwent laparoscopic nephrectomy (LN) and 22 open nephrectomy (ON). The mean age in the LN group was 53.82 years ± 13.44, and 56.2 years ± 15 (p-value 0.535) in ON group. Forty-seven patients were of Omani descent and 9 patients were expatiates. The mean tumor size was 6.25 ± 3.16 and 9.2 ± 5.20 cm for the LN and ON groups, respectively. More than 55% cases were incidentally diagnosed. Over the years there has been a trend towards LN. Conclusion: In our study, we found a trend towards early diagnosis with majority of cancers discovered incidentally. We also recognized that laparoscopic approach is more commonly employed in the surgical management with acceptable morbidity. These trends are in congruence with the global literature. \u0000Keywords: nephrectomy, laparoscopic, open, renal cell carcinoma","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"35 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141346248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Septum Pellucidum Cavernous Malformation 透明膜下腔畸形

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.035

Asma AlHatmi, Rajeev Kariyattil, Eiman Al-Ajmi

引用次数: 0

Assessment of Albumin Usage Patterns and Appropriateness in a Comprehensive Cancer Centre 综合癌症中心白蛋白使用模式及适宜性评估

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.029

Asma'a Al-Kharabsheh, L. Nazer, Wedad Awad, Ala'a Ghanem, Rand Al-Hadaddin, Batool Bani Amer, Hadeel Thawaibeh, Nour Mustafa, Rula Al-Najjar, Abeer Al-Rabaiah, Saad Jaddoua

{"title":"Assessment of Albumin Usage Patterns and Appropriateness in a Comprehensive Cancer Centre","authors":"Asma'a Al-Kharabsheh, L. Nazer, Wedad Awad, Ala'a Ghanem, Rand Al-Hadaddin, Batool Bani Amer, Hadeel Thawaibeh, Nour Mustafa, Rula Al-Najjar, Abeer Al-Rabaiah, Saad Jaddoua","doi":"10.18295/squmj.6.2024.029","DOIUrl":"https://doi.org/10.18295/squmj.6.2024.029","url":null,"abstract":"Objectives: Albumin is commonly used for various indications. However, conflicting data exists regarding its appropriate use in different clinical cases. In this study we aim to determine the pattern and appropriateness of albumin use among cancer patients treated at a comprehensive cancer center in Jordan. Methods: A retrospective analysis was conducted on adult cancer patients who were prescribed albumin between January 2019 and July 2020, in the outpatient and inpatient settings. Patient- and albumin-related data were collected, which included demographics, prescribing services, indications, and dosing regimens. We conducted thorough research using PubMed, and reviewed the related guidelines, drug information resources and the package insert to evaluate the appropriateness of albumin's indications and dosing regimens. Results: Albumin was prescribed to 1,361 patients during the study period. Each patient received an average of 74.4 ± 89 (SD) grams of albumin for an average of 2.6 ± 1.8 (SD) days. Albumin use was considered appropriate in 69% of the patients. The critical care service had the highest albumin consumption, with 37% of the prescribing being for the indication of septic shock. Inappropriate use was observed among the medical solid tumor service (40.8 % of their prescriptions) and was most commonly prescribed for edema (28%). Conclusion: To our knowledge, this study represents the first to evaluate a large cohort of oncology patients. In about one third of the cases albumin prescribed indications were considered inappropriate. Continuous education on appropriate usage and regular evaluations of guideline implementation is necessary to ensure appropriate utilization. \u0000Keywords: Albumins*/therapeutic use, drug utilization review, neoplasms, cancer care facilities, Jordan.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"56 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141348219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Hormonal and Non-hormonal Vaginal Gel Preparations on Female Sexual Satisfaction Index in Postmenopausal Women with Sexual Dysfunction Syndrome 激素类和非激素类阴道凝胶制剂对绝经后性功能障碍综合征妇女性满意度指数的影响

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.040

Ahmed Soliman, Hanaa Alrashidi, Mohamed A Mohamed, Reem Ghorab, Nihal Al Riyami, Ahmed SA Ashour, Yasmine A Mohammed, Ahmed H Saad

{"title":"Efficacy of Hormonal and Non-hormonal Vaginal Gel Preparations on Female Sexual Satisfaction Index in Postmenopausal Women with Sexual Dysfunction Syndrome","authors":"Ahmed Soliman, Hanaa Alrashidi, Mohamed A Mohamed, Reem Ghorab, Nihal Al Riyami, Ahmed SA Ashour, Yasmine A Mohammed, Ahmed H Saad","doi":"10.18295/squmj.6.2024.040","DOIUrl":"https://doi.org/10.18295/squmj.6.2024.040","url":null,"abstract":"We aimed to compare efficacy of vaginal gel preparations versus placebo in postmenopausal women with sexual dysfunction syndrome. We searched electronic databases from inception to January 2023. We included trials reporting Female Sexual Function Index (FSFI) which compared hormonal (estrogen, oxytocin) and/or non-hormonal (chamomile, fennel) interventions versus placebo. We used Cochrane Risk of Bias assessment tool I to evaluate studies quality. Eight trials (N=672 participants) were included. Total FSFI endpoint score was higher in the vaginal gel preparations group (MD: 6.67; 95% CI: [3.79, 9.55]; p< 0.001) than placebo. Non-hormonal gel preparations had higher FSFI total score (MD: 6.73, 95% CI: [4.7, 8.76], p< 0.001) than hormonal preparations (MD: 2.75, 95% CI: [1.87,3.64], p< 0.001). Non-hormonal interventions increased all FSFI domains. We conclude that Chamomile and fennel vaginal gel preparations could improve overall FSFI six domains score, which reflects on postmenopausal women's sexual activity and satisfaction. \u0000Keywords: menopause, psychological sexual dysfunction, estrogen, Chamomile, Meta-analysis","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"32 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141350074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between Internet Addiction and Dietary Habits among Omani Junior College Students 阿曼中专学生的网瘾与饮食习惯之间的关系

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.034

M. Joseph, Jansirani Natarajan, Huda Al-Hinai

{"title":"Association between Internet Addiction and Dietary Habits among Omani Junior College Students","authors":"M. Joseph, Jansirani Natarajan, Huda Al-Hinai","doi":"10.18295/squmj.6.2024.034","DOIUrl":"https://doi.org/10.18295/squmj.6.2024.034","url":null,"abstract":"Objectives: To investigate the association between internet addiction and dietary habits among Omani junior college students. Methods: In this cross-sectional study at Sultan Qaboos University, 377 junior college students were surveyed in November 2020 using demographic data, the Compulsive Internet Use Scale, and a dietary habits questionnaire. Chi-square cross-tabulation analyses explored the relationship between internet addiction and dietary habits. Results: Overall, 59.9% of junior college students were identified as having an internet addiction. Within this group, 62.8% reported reduced meal sizes and 54.4% reported a decrease in appetite. There was a statistically significant difference in both meal size (X2=30.528, p<0.001) and appetite changes (X2=28.731, p<0.001) among student with different levels of internet addiction. These results suggest a possible link between internet addiction and altered dietary habits among this population. Conclusion: This study highlights the need for strategies that encourage healthy living behaviors and raise awareness about the adverse effects of internet addiction. \u0000Keywords: Internet addiction disorder; diet; Students; appetite; Oman","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"24 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141347817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unbridled Advertising of Female Cosmetic Genitoplasty Procedures in the Absence of Health Policy-making in the World 在全球缺乏卫生政策制定的情况下肆意宣传女性生殖器整形手术

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.037

Elham Azmoude, N. J. Shoorab, S. E. Zagami

引用次数: 0

Development of Organoids from Malignant Ascites for Cancer Research in Oman 阿曼从恶性腹水中提取有机体用于癌症研究

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.028

Fazal Khan, Nausheen Yaqoob, Aida H AlYahyaee, Shoaib A AlZadjali, I. Burney

引用次数: 0

Evaluation of Clinical Efficacy of Biodegradable Chip Containing Salvadora persica Extract in Chitosan Base as an Adjunct to Scaling and Root Planning in the Management of Periodontitis 壳聚糖基中含有萨尔瓦多柿提取物的生物可降解芯片作为洗牙和牙根规划治疗牙周炎的辅助手段的临床疗效评估

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.030

F. Al-Bayaty, A. A. Kamaruddin, Mohd. A. Ismail, Mazen MJ Al-Obaidi

{"title":"Evaluation of Clinical Efficacy of Biodegradable Chip Containing Salvadora persica Extract in Chitosan Base as an Adjunct to Scaling and Root Planning in the Management of Periodontitis","authors":"F. Al-Bayaty, A. A. Kamaruddin, Mohd. A. Ismail, Mazen MJ Al-Obaidi","doi":"10.18295/squmj.6.2024.030","DOIUrl":"https://doi.org/10.18295/squmj.6.2024.030","url":null,"abstract":"Objective: The objectives of this study were to develop two biodegradable periodontal chips containing Salvadora persica or Benzyl isothiocyanate (BITC) extract and evaluate its clinical effectiveness in managing periodontitis. Methods: Chips were formulated from Salvadora persica, Benzyl isothiocyanate (BITC) and chitosan; twelve patients with periodontal pockets measuring ≥5 mm participated in this study. Overall, 240 periodontal pockets were evaluated. All patients were treated with full mouth scaling and root planning (SRP) at baseline. Periodontal pockets were divided into four groups. One of which is the control group, while group two received plain chitosan chip. Group three received chips containing Salvadora persica extract, and group four received chips containing BITC. Plaque index (PI), bleeding on probing (BOP), periodontal probing pocket (PPD) depth, and clinical attachment levels (CAL) using acrylic stents were recorded at days 0 and 60 only. Results: Data were statistically analysed; Chi-square t-test and an ANOVA were used. Results showed significant improvement in plaque index, bleeding on probing, and reduction in periodontal pocket depth in all four groups (p<0.05). The gain in clinical attachment level was significantly higher (p<0.005) among the group receiving Salvadora persica chips compared to the control and other chip-treated groups. Conclusion: Periodontal chips containing S. persica can be used as adjuncts to treat patients with periodontitis. \u0000Keywords: Chitosan; Periodontal chip; Miswak extract; Benzyl isothiocyanate; Periodontitis.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"12 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141348805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Schwannoma of the Appendix Mimicking a Metastatic Breast Cancer 模仿转移性乳腺癌的阑尾许旺瘤

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.041

Z. Al-ishaq, Alonood Al-Sulaimani, Badriya Al-Qassabi, Fathiya AlRahbi, Khalid Al Baimani, Jawa Z. Muhammad, A. Aljarrah

引用次数: 0

Prevalence, clinico-laboratory features and outcome of paediatric scrub typhus cases in a tertiary care centre in Eastern India 印度东部一家三级护理中心儿科恙虫病病例的发病率、临床实验室特征和治疗结果

Sultan Qaboos University Medical Journal Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.032

R. Murmu, Gobinda Mondal, Koushik Biswas, Ashok K Bala

{"title":"Prevalence, clinico-laboratory features and outcome of paediatric scrub typhus cases in a tertiary care centre in Eastern India","authors":"R. Murmu, Gobinda Mondal, Koushik Biswas, Ashok K Bala","doi":"10.18295/squmj.6.2024.032","DOIUrl":"https://doi.org/10.18295/squmj.6.2024.032","url":null,"abstract":"Objective: Scrub typhus is the most common rickettsial disease in India, caused by Orientia tsutsugamushi, and transmitted by chigger mites. Previously reported in South India, but the resurgence of cases is currently reported in Eastern India. This study aimed to estimate the prevalence and describe the clinico-laboratory profile of scrub typhus in paediatric patients (1-12 years old) in Eastern India. Methods: A prospective observational study was conducted from January to December 2019 in a paediatric tertiary care centre in Kolkata. All acute undifferentiated febrile illness cases (1-12 years) were tested for scrub typhus serology by ELISA. Demographic details, clinical features, laboratory findings, complications and treatment outcomes of scrub typhus patients were extracted in Microsoft Excel spreadsheet and further analysed. Results: The prevalence of scrub typhus among acute febrile illness patients was 4.5 %. The mean age of patients was 5.22 years and the majority (64.2 %) had a fever for the last 7-14 days. Gastrointestinal symptoms like vomiting (43.3 %) and pain abdominal (32.8 %) were frequently seen. Major clinical signs were hepatomegaly (41.8 %) and splenomegaly (31.3 %). Complication was observed in 74.6 %, with thrombocytopenia (40.3 %) and meningoencephalitis (29.9 %) being more frequent. The case fatality rate was 1.5 %. Conclusions: Classical eschar was absent in three-fourth of our patients, hence we advocate laboratory scrub typhus testing for all suspected cases in endemic region. Thrombocytopenia and meningoencephalitis were prominent complications in our study. Prompt treatment with doxycycline and/or azithromycin could prevent complications and reduce mortality. \u0000Keywords: Hospital Stay; Hospitalization, patient discharge; General Internal Medicine","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"48 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0