Sultan Qaboos University Medical Journal最新文献

筛选
英文 中文
Unveiling the Marvels of 3D Echo: Illuminating prosthetic mitral valve dehiscence through 3D transillumination. 揭示3D回声的奇迹:通过3D透光照明假体二尖瓣开裂。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/squmj.10.2024.061
Sheeraz Ahmad, Muhammad A Sadiq, Jai Parkash, Ahmad Kamal, Abdullah Al Ismaili, Fahad Al Kindi
{"title":"Unveiling the Marvels of 3D Echo: <i>Illuminating prosthetic mitral valve dehiscence through 3D transillumination</i>.","authors":"Sheeraz Ahmad, Muhammad A Sadiq, Jai Parkash, Ahmad Kamal, Abdullah Al Ismaili, Fahad Al Kindi","doi":"10.18295/squmj.10.2024.061","DOIUrl":"10.18295/squmj.10.2024.061","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"296-299"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology, Risk Factors and Clinical Outcome of Candidaemia: A decade-long experience at a university hospital in Oman. 念珠菌血症的流行病学、危险因素和临床结果:阿曼一所大学医院长达十年的经验。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2832
Tasneem Al Salmani, Asmaa S Mahdi, Abdullah Balkhair, Turkiya Al Siyabi, Hashim Ba Wazir
{"title":"Epidemiology, Risk Factors and Clinical Outcome of Candidaemia: <i>A decade-long experience at a university hospital in Oman</i>.","authors":"Tasneem Al Salmani, Asmaa S Mahdi, Abdullah Balkhair, Turkiya Al Siyabi, Hashim Ba Wazir","doi":"10.18295/2075-0528.2832","DOIUrl":"10.18295/2075-0528.2832","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to examine a decade-long epidemiology of candidaemia to explore the risk factors associated with it, and describe its clinical outcomes in hospitalised adult patients.</p><p><strong>Methods: </strong>This retrospective observational study was conducted at Sultan Qaboos University Hospital, Muscat, Oman. Adult patients with candidaemia hospitalised between January 2007 and December 2016 were included. The hospital infection control department surveillance registry on bloodstream infections (BSIs) was used to identify <i>Candida</i> BSIs. Patients' electronic medical records were searched for demographic characteristics, clinical risk factors and outcomes.</p><p><strong>Results: </strong><i>Candida albicans</i> was the most common <i>Candida</i> species among 152 patients with candidaemia comprising 25.0% of all <i>Candida</i> blood culture isolates. <i>Nakaseomyces glabrata</i>, <i>C. tropicalis</i> and <i>C. parapsilosis</i> were the most frequently isolated non-<i>albicans</i> species. Past antibiotics use, presence of central venous catheters, intensive care unit admission, diabetes mellitus, sickle cell disease and solid cancer were the most commonly identified underlying risk factors for candidaemia. A total of 30 days' all-cause mortality was 53.3% among all patients with candidaemia.</p><p><strong>Conclusions: </strong>This study found an increasing trend of non-<i>albicans Candida.</i> Diabetes was the most identified risk factor for candidaemia. A relatively low rate of initiation of empirical antifungal therapy in at-risk patients was found. Unacceptably high mortality rates and prolonged hospital stay of patients with candidaemia are a call for action.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"233-241"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re: Meniscal Ossicle. 回复:半月板听骨。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2882
Vitorino Modesto Dos Santos, Andressa Plaça Tedeschi
{"title":"Re: Meniscal Ossicle.","authors":"Vitorino Modesto Dos Santos, Andressa Plaça Tedeschi","doi":"10.18295/2075-0528.2882","DOIUrl":"10.18295/2075-0528.2882","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"598-599"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Ear Health, Care Practices, and Hearing Loss on Academic Performance among Male Adolescents in Residential Schools: A cross-sectional study in Eastern India. 耳部健康、护理实践和听力损失对寄宿学校男性青少年学习成绩的影响:印度东部的一项横断面研究
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.6872
Sumeet Angral, Bijit Biswas, Ksbs Krishna Sasanka, Gulistan Bano
{"title":"Effect of Ear Health, Care Practices, and Hearing Loss on Academic Performance among Male Adolescents in Residential Schools: <i>A cross-sectional study in Eastern India</i>.","authors":"Sumeet Angral, Bijit Biswas, Ksbs Krishna Sasanka, Gulistan Bano","doi":"10.18295/2075-0528.6872","DOIUrl":"10.18295/2075-0528.6872","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the association between ear health, ear care practices, and academic performance among male adolescents in residential schools.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 684 male adolescents residing in residential schools in Deoghar, Jharkhand, India, during World Hearing Day 2023. Data were collected on socio-demographic characteristics, ear care practices, and academic performance. Comprehensive ear examinations and pure tone audiometry were performed to assess ear morbidity and hearing thresholds.</p><p><strong>Results: </strong>Ear morbidity was identified in 43% of participants, with bilateral involvement in 85% of these cases. Ear-related symptoms were reported by 26.3% of participants, including ear pain (46.1%) and hearing difficulty (37.2%). Chronic ear morbidity was present in 36.5% of the cohort. Hearing loss was detected in 5% of participants, with 4.6% experiencing mild and 0.4% moderate hearing loss; among these, 74.1% had bilateral involvement. Self-ear cleaning was commonly practiced (93%), predominantly using cotton buds (85.2%). Multivariate analysis showed that inserting substances into the ear (Spearman's rho [ρ] = -0.095; <i>P</i> = 0.014), exposure to loud firecrackers (ρ = -0.095; <i>P</i> = 0.014), being slapped hard (ρ = -0.102; <i>P</i> = 0.008), presence of chronic ear morbidity (ρ = -0.185; <i>P</i> <0.001), and hearing loss (ρ = -0.292; <i>P</i> <0.001) were significantly and negatively correlated with academic performance.</p><p><strong>Conclusion: </strong>The study reveals a high prevalence of ear morbidities, which were associated with lower academic performance among the study population. Regular screenings, educational interventions and timely healthcare are crucial to protect this vulnerable group.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"600-610"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation and Evaluation of a Weight Management Programme for Overweight or Obese Pregnant Women: A Randomised Controlled Trial. 超重或肥胖孕妇体重管理方案的实施和评价:一项随机对照试验。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2878
Elahe Banafshe, Nahid Javadifar, Zahra Abbaspoor, Saeed Ghanbari, Majid Karandish
{"title":"Implementation and Evaluation of a Weight Management Programme for Overweight or Obese Pregnant Women: <i>A Randomised Controlled Trial</i>.","authors":"Elahe Banafshe, Nahid Javadifar, Zahra Abbaspoor, Saeed Ghanbari, Majid Karandish","doi":"10.18295/2075-0528.2878","DOIUrl":"10.18295/2075-0528.2878","url":null,"abstract":"<p><strong>Objectives: </strong>Obesity is a major health concern, particularly among women of reproductive age. This study aimed to evaluate the effectiveness of a psychosocial-based intervention on weight management and pregnancy outcomes in overweight or obese pregnant women.</p><p><strong>Methods: </strong>This randomised controlled trial included overweight or obese pregnant women from healthcare centres affiliated with Jundishapur University of Medical Sciences in Ahvaz, Iran and was conducted from June to December 2023. Participants were randomly assigned to an intervention or control group. The intervention group received a comprehensive weight management programme during pregnancy, while the control group received standard prenatal care.</p><p><strong>Results: </strong>A total of 202 women participated in this study. The intervention helped improve appropriate weight gain, healthier food choices (<i>P</i> < 0.001), and increased physical activity. In overweight women, 29.3% of the intervention group and 20.6% of the control group achieved normal weight gain. Among obese women, 39.3% in the intervention group and 37% in the control group reached the recommended weight gain. Physical activity scores improved significantly in both groups, with the intervention group showing greater changes (<i>P</i> = 0.0001). However, there were no significant differences in pregnancy outcomes, including gestational diabetes (<i>P</i> = 0.533), preeclampsia (<i>P</i> = 0.948), and caesarean section rates (<i>P</i> = 0.489).</p><p><strong>Conclusion: </strong>The psychosocial-based intervention used in this study positively impacted nutritional behaviour and physical activity but did not significantly reduce adverse pregnancy outcomes. More comprehensive, personalised and long-term interventions are recommended.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"580-591"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Accuracy of Abdominal Ultrasonographic Sliding Sign in the Evaluation of Severe Intra-Abdominal Adhesions Involving the Uterus in Women Undergoing Repeat Caesarean Delivery: Systematic review and meta-analysis. 腹部超声滑动征在评估重复剖宫产妇女严重腹内粘连累及子宫中的诊断准确性:系统回顾和荟萃分析。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/squmj.10.2024.063
Amira M Taha, Wesam A Moawad, Sara A A Saed, Tala J Alhejazi, Youstina A Sabri, Mohamed Abd-ElGawad, Juan L Alcazar, Nihal Al Riyami, Ayatallah Khafagy, Yasmine A Mohammed, Ahmed H Saad
{"title":"Diagnostic Accuracy of Abdominal Ultrasonographic Sliding Sign in the Evaluation of Severe Intra-Abdominal Adhesions Involving the Uterus in Women Undergoing Repeat Caesarean Delivery: <i>Systematic review and meta-analysis</i>.","authors":"Amira M Taha, Wesam A Moawad, Sara A A Saed, Tala J Alhejazi, Youstina A Sabri, Mohamed Abd-ElGawad, Juan L Alcazar, Nihal Al Riyami, Ayatallah Khafagy, Yasmine A Mohammed, Ahmed H Saad","doi":"10.18295/squmj.10.2024.063","DOIUrl":"10.18295/squmj.10.2024.063","url":null,"abstract":"<p><p>This review aimed to assess diagnostic accuracy of transabdominal ultrasonography (TAS) sliding sign in diagnosing severe intra-abdominal adhesions with repeated Caesarean delivery (CD). PubMed, Google Scholar, Web of Science and Scopus were searched for published studies until October 2022. Studies evaluating the sliding sign as a predictor of intra-abdominal adhesions after repeat CD were included. STATA and Comprehensive Meta-Analysis for meta-analysis was used. A total of 7 studies (1,318 patients) were included. For identifying severe intra-abdominal adhesions, sliding sign on TAS had a combined sensitivity (64%, 95% confidence interval [CI]: 55-71%), specificity (93%, 95% CI: 89-96%), positive likelihood ratio (9.5, 95% CI: 5.7-16), negative likelihood ratio (0.39, 95% CI: 0.31-0.49) and diagnostic odds ratio (24, 95% CI: 13-46). Prediction intervals for sensitivity and specificity were 0.444-0.786 and 0.711-0.985, respectively. Sliding sign on TAS is a simple, non-invasive, good negative and practical method to exclude severe intra-abdominal adhesions involving the uterus with low sensitivity and high specificity.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"29-37"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Citrobacter Sedlakii as a Rare Cause of Brain Abscess in a Late-Preterm Omani Infant: Case report and literature review. 塞德拉基柠檬酸杆菌是阿曼晚期早产婴儿脑脓肿的罕见病因:病例报告和文献复习。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.7458
Mohammed S Al Reesi, Moza Al Mamari, Sara Magzoub, Yasser AbdulRazek
{"title":"<i>Citrobacter Sedlakii</i> as a Rare Cause of Brain Abscess in a Late-Preterm Omani Infant: <i>Case report and literature review</i>.","authors":"Mohammed S Al Reesi, Moza Al Mamari, Sara Magzoub, Yasser AbdulRazek","doi":"10.18295/2075-0528.7458","DOIUrl":"10.18295/2075-0528.7458","url":null,"abstract":"<p><p>Brain abscess in neonates is rare but remains a severe, life-threatening complication of meningitis with significant morbidity and mortality. While <i>Citrobacter koseri</i> and <i>Citrobacter freundii</i> are commonly implicated in brain-abscess formation, <i>Citrobacter sedlakii</i> is an uncommon causative pathogen. To date, only two cases of neonatal brain abscess caused by <i>C. sedlakii</i> have been reported in the literature. Early diagnosis, timely surgical intervention and prompt antibiotic therapy are critical to achieving a favourable outcome. A third case of a <i>C. sedlakii</i> brain abscess in a preterm infant, presenting in 2024 to a tertiary-care hospital in Oman, is reported together with a brief review of the literature.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12709210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145782812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum: Mycoplasma pneumoniae-Induced Mucositis Sine Rash: Case report in an adult patient. 更正:肺炎支原体引起的粘膜炎正弦皮疹:一个成人患者的病例报告。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2928
{"title":"Erratum: Mycoplasma pneumoniae-Induced Mucositis Sine Rash: <i>Case report in an adult patient</i>.","authors":"","doi":"10.18295/2075-0528.2928","DOIUrl":"10.18295/2075-0528.2928","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.18295/2075-0528.2907.].</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"938"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12709208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145782829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Strategies for Unilateral Pulmonary Artery Agenesis: A case series. 单侧肺动脉发育不全的手术治疗策略:一个病例系列。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2951
Amr Abolwafa, Alaa Al-Lawati, Hamood Nasar Al-Kindi, Sunny Zacharias, Pranav Subbaraya Kandachar, Madan Mohan Maddali
{"title":"Surgical Strategies for Unilateral Pulmonary Artery Agenesis: <i>A case series</i>.","authors":"Amr Abolwafa, Alaa Al-Lawati, Hamood Nasar Al-Kindi, Sunny Zacharias, Pranav Subbaraya Kandachar, Madan Mohan Maddali","doi":"10.18295/2075-0528.2951","DOIUrl":"10.18295/2075-0528.2951","url":null,"abstract":"<p><p>Unilateral pulmonary artery agenesis, typically affecting the right pulmonary artery, is a rare condition that may lead to congestive heart failure or pulmonary hypertension in infants and early surgical intervention improves outcomes. We report 5 cases from Muscat, Oman, of unilateral pulmonary artery agenesis who underwent surgical correction between November 2019 and August 2023, at an average age of 4.4 months. Most presented with cyanosis or respiratory distress and all had pulmonary hypertension confirmed by imaging. Surgical approaches included Gore-Tex conduit placement, autologous pericardial reconstruction and patent ductus arteriosus unifocalisation. All patients successfully restored pulmonary blood flow with no perioperative mortality. The median intensive unit care stay was 13 days and the median hospital stay was 20 days. Only 1 patient required repeat surgery for graft compression. Over a 27.6-month follow-up period, 4 patients showed regression of pulmonary hypertension and 2 underwent pulmonary angioplasty, reinforcing the benefits of timely intervention.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"13-19"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12797268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anthracycline-Induced Cardiomyopathy in Breast Cancer Patients in Oman: A retrospective study. 阿曼乳腺癌患者蒽环类药物引起的心肌病:一项回顾性研究。
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2891
Hussain A Al-Lawati, Khalid Al Baimani, Mohammed N Al Rawahi
{"title":"Anthracycline-Induced Cardiomyopathy in Breast Cancer Patients in Oman: <i>A retrospective study</i>.","authors":"Hussain A Al-Lawati, Khalid Al Baimani, Mohammed N Al Rawahi","doi":"10.18295/2075-0528.2891","DOIUrl":"10.18295/2075-0528.2891","url":null,"abstract":"<p><strong>Objectives: </strong>Anthracyclines are widely used in the treatment of breast cancer. One of the known adverse effects of anthracyclines is anthracycline-induced cardiomyopathy. Studies done worldwide showed that the prevalence of chemotherapy-induced cardiomyopathy is approximately 9%. However, studies evaluating this complication prevalence, risk factors and cumulative dose are lacking in Oman. This study aimed to investigate the prevalence of anthracycline-induced cardiomyopathy among breast cancer patients in Oman.</p><p><strong>Methods: </strong>This retrospective study included all breast cancer patients who received anthracycline-based chemotherapy exclusively between September 2008 and December 2020 at Sultan Qaboos University Hospital in Muscat. Patients with partial treatment, coexisting heart failure and who did not receive anthracycline as part of the chemotherapy regimen were excluded. Chemotherapy-induced cardiomyopathy was defined as a drop of left ventricular ejection fraction >10% from the patient's baseline during or after receiving anthracycline-based chemotherapy.</p><p><strong>Results: </strong>A total of 385 patients were included in this study of which 39 (10.1%) developed cardiomyopathy after exposure to anthracyclines. The mean cumulative dose of doxorubicin among these patients was 239 mg/m<sup>2</sup> (epirubicin was converted to doxorubicin equivalent dose). Univariate analysis showed that the risk of anthracycline-induced cardiomyopathy was influenced by cardiovascular risk factors such as hypertension (33.3%), diabetes (25.6%), dyslipidaemia (20.5%) and previous cardiovascular medications use (10.3%). Trastuzumab exposure significantly correlated with an increased risk of developing cardiomyopathy (<i>P</i> < 0.001). However, multivariate analysis did not show any significant association.</p><p><strong>Conclusions: </strong>Anthracycline-induced cardiomyopathy was influenced by various cardiovascular risk factors as well as trastuzumab exposure. Further studies are recommended to investigate the prevention and management of anthracycline-induced cardiomyopathy.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"839-846"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12538945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145347487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书