Mohammed S Al Reesi, Latifa A Al Muttawa, Mariam A Albolushi, Naima S Al Risi
{"title":"伊莉莎白菌感染-新生儿和婴儿败血症和脑膜炎的重要新发原因:来自阿曼北巴蒂纳地区的病例系列和文献综述。","authors":"Mohammed S Al Reesi, Latifa A Al Muttawa, Mariam A Albolushi, Naima S Al Risi","doi":"10.18295/2075-0528.2895","DOIUrl":null,"url":null,"abstract":"<p><p><i>Elizabethkingi</i>a species, particularly <i>E. anophelis</i> and <i>E. meningoseptica</i>, are gram negative bacilli known to be associated with neonatal infections. Although these bacteria are rare, they are highly concerning pathogens associated with severe sepsis, bacteraemia and meningitis in neonates and immunocompromised individuals. Managing <i>Elizabethkingia</i> infections presents significant challenges because of their multidrug resistance, including resistance to most β-lactam agents. They have been implicated in both nosocomial and community outbreaks worldwide, often with high mortality rates. In Oman, <i>Elizabethkingia</i> infections are underreported, with only 1 publication documenting 2 cases of <i>E. meningoseptica</i> bacteraemia and meningitis, both of which were successfully treated. To the best of the authors' knowledge, the current case series of 7 <i>Elizabethkingia</i> infections represents the largest cohort reported from Oman to date. In this report, the clinical manifestations and management strategies and a relevant literature are presented.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"708-716"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445316/pdf/","citationCount":"0","resultStr":"{\"title\":\"<i>Elizabethkingia</i> Infections - An Important Emerging Cause of Sepsis and Meningitis in Neonates and Infants: <i>Case Series from North Batinah Region, Oman, and literature review</i>.\",\"authors\":\"Mohammed S Al Reesi, Latifa A Al Muttawa, Mariam A Albolushi, Naima S Al Risi\",\"doi\":\"10.18295/2075-0528.2895\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Elizabethkingi</i>a species, particularly <i>E. anophelis</i> and <i>E. meningoseptica</i>, are gram negative bacilli known to be associated with neonatal infections. Although these bacteria are rare, they are highly concerning pathogens associated with severe sepsis, bacteraemia and meningitis in neonates and immunocompromised individuals. Managing <i>Elizabethkingia</i> infections presents significant challenges because of their multidrug resistance, including resistance to most β-lactam agents. They have been implicated in both nosocomial and community outbreaks worldwide, often with high mortality rates. In Oman, <i>Elizabethkingia</i> infections are underreported, with only 1 publication documenting 2 cases of <i>E. meningoseptica</i> bacteraemia and meningitis, both of which were successfully treated. To the best of the authors' knowledge, the current case series of 7 <i>Elizabethkingia</i> infections represents the largest cohort reported from Oman to date. In this report, the clinical manifestations and management strategies and a relevant literature are presented.</p>\",\"PeriodicalId\":22083,\"journal\":{\"name\":\"Sultan Qaboos University Medical Journal\",\"volume\":\"25 1\",\"pages\":\"708-716\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445316/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sultan Qaboos University Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18295/2075-0528.2895\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sultan Qaboos University Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18295/2075-0528.2895","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Elizabethkingia Infections - An Important Emerging Cause of Sepsis and Meningitis in Neonates and Infants: Case Series from North Batinah Region, Oman, and literature review.
Elizabethkingia species, particularly E. anophelis and E. meningoseptica, are gram negative bacilli known to be associated with neonatal infections. Although these bacteria are rare, they are highly concerning pathogens associated with severe sepsis, bacteraemia and meningitis in neonates and immunocompromised individuals. Managing Elizabethkingia infections presents significant challenges because of their multidrug resistance, including resistance to most β-lactam agents. They have been implicated in both nosocomial and community outbreaks worldwide, often with high mortality rates. In Oman, Elizabethkingia infections are underreported, with only 1 publication documenting 2 cases of E. meningoseptica bacteraemia and meningitis, both of which were successfully treated. To the best of the authors' knowledge, the current case series of 7 Elizabethkingia infections represents the largest cohort reported from Oman to date. In this report, the clinical manifestations and management strategies and a relevant literature are presented.