伊莉莎白菌感染-新生儿和婴儿败血症和脑膜炎的重要新发原因:来自阿曼北巴蒂纳地区的病例系列和文献综述。

Q3 Medicine
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI:10.18295/2075-0528.2895
Mohammed S Al Reesi, Latifa A Al Muttawa, Mariam A Albolushi, Naima S Al Risi
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引用次数: 0

摘要

伊莉莎白杆菌属,特别是按蚊和脑膜炎脓毒杆菌属,是已知与新生儿感染有关的革兰氏阴性杆菌。虽然这些细菌很罕见,但它们是与新生儿和免疫功能低下个体的严重败血症、菌血症和脑膜炎相关的高度关注的病原体。管理伊丽莎白菌感染面临重大挑战,因为它们具有多药耐药性,包括对大多数β-内酰胺类药物的耐药性。它们与世界各地的医院和社区暴发有关,通常死亡率很高。在阿曼,伊丽莎白金杆菌感染的报告不足,只有1份出版物记录了2例脑膜炎脓毒杆菌菌血症和脑膜炎病例,这两例病例均得到了成功治疗。据作者所知,目前的7例伊丽莎白金氏菌感染病例系列是迄今为止阿曼报告的最大队列。本文就其临床表现、治疗策略及相关文献作一介绍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Elizabethkingia Infections - An Important Emerging Cause of Sepsis and Meningitis in Neonates and Infants: Case Series from North Batinah Region, Oman, and literature review.

Elizabethkingia species, particularly E. anophelis and E. meningoseptica, are gram negative bacilli known to be associated with neonatal infections. Although these bacteria are rare, they are highly concerning pathogens associated with severe sepsis, bacteraemia and meningitis in neonates and immunocompromised individuals. Managing Elizabethkingia infections presents significant challenges because of their multidrug resistance, including resistance to most β-lactam agents. They have been implicated in both nosocomial and community outbreaks worldwide, often with high mortality rates. In Oman, Elizabethkingia infections are underreported, with only 1 publication documenting 2 cases of E. meningoseptica bacteraemia and meningitis, both of which were successfully treated. To the best of the authors' knowledge, the current case series of 7 Elizabethkingia infections represents the largest cohort reported from Oman to date. In this report, the clinical manifestations and management strategies and a relevant literature are presented.

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CiteScore
2.00
自引率
0.00%
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审稿时长
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