Scientific Reports最新文献

{"title":"Short-term cone beam CT study on bone mass changes post touch-controlled minimally invasive mandibular molar implant.","authors":"Wenchao Li, Ning Ruan, Yuan Tian, Senhao Li, Weize Han, Xinxin Zhang, Haoyang Yu, Yu Xie","doi":"10.1038/s41598-024-84209-2","DOIUrl":"https://doi.org/10.1038/s41598-024-84209-2","url":null,"abstract":"<p><p>This study aimed to investigate the change of peri-implant bone mass after touch-controlled, minimally invasive implantation in the mandibular first molar region by cone-beam computed tomography (CBCT). A retrospective study was conducted, involving 60 implants in the mandibular first molar region. Touch-controlled, minimally invasive implantation was performed, and healing abutments were installed after surgery. CBCT scans were obtained at four time points: on the day of surgery (T0) and at 1 month (T1) and 6 months (T2) after surgery. Implant retention, as well as horizontal and vertical bone absorption, both bucco-lingually and in the proximal and distal regions, was measured at each time point. The implant retention at T2 was 100%. Bone resorption was observed at the proximal and distal sites of the implant as early as at T1, with more noticeable resorption at T2. Compared with T1, there was a significant increase in bone resorption, and the resorption amount tended to stabilize by T2. Horizontal bone resorption was not evident. Briefly, following touch-controlled, minimally invasive implantation of mandibular first molars, peri-implant vertical bone resorption was observed in the proximal, distal, and bucco-lingual regions, while horizontal bone resorption was not apparent. These findings provide valuable guidance for implant clinicians in selecting optimal surgical techniques.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10923"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autologous glueless simple oral mucosal transplantation for the repair of limbal stem cell deficiency ocular surface in a rabbit model.","authors":"Kai Zhang, Wei Liu, Xiaoxiao Ren, Yiqiang Yin, Wenming Chen, Fen Chen, Jing Zhu, Lin Shen","doi":"10.1038/s41598-025-96088-2","DOIUrl":"https://doi.org/10.1038/s41598-025-96088-2","url":null,"abstract":"<p><p>This study aims to investigate the efficacy of glueless simple oral mucosal transplantation to prevent the development of the limbal stem cell deficiency in rabbit model. Rabbit limbal stem cell deficiency (LSCD) models were constructed with alcohol and mechanical scraping. The oral mucosa and limbal tissue were harvested and cut into small pieces. Microincisions were made on the corneal limbus and the precut pieces were inserted in. Animals were divided to three groups: glueless simple oral mucosal epithelium transplantation (GSOMT), glueless simple limbal epithelium transplantation (GSLET) and LSCD group. Corneal epithelium defects, opacity and neovascularization were observed after surgery by slit-lamp microscopy. Neovascularization and epithelialization were scored. HE staining and immunohistochemistry of CK12, CK13, p63 were performed after observation. In the LSCD group, corneal neovascularization and opacification were present and epithelial defects were still observed by 4 months. In the GSOMT group, the cornea was clear and epithelialization was complete by 15 days; the fluorescein staining scores and neovascularization were significantly lower in GSOMT group comparing with LSCD group. There were no significant differences between GSOMT group and GSLET group. Histological study showed that the transplanted oral mucosal graft blend into the recipient corneal tissue well after surgery and the morphology or phenotype of the corneal epithelium surrounding the graft were similar to that of normal corneal epithelium. The glueless simple oral mucosal transplantation successfully prevented the development of the limbal stem cell deficiency in rabbit model. This method avoids the limited graft sources and the allogeneic rejection problem especially in binocular LSCDs. GSOMT could become a new surgery method for treating LSCD and this basic research lays a foundation for next clinical promotion and application.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10855"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A BiLSTM model enhanced with multi-objective arithmetic optimization for COVID-19 diagnosis from CT images.","authors":"Liang Chen, Xin Lin, Liangliang Ma, Chao Wang","doi":"10.1038/s41598-025-94654-2","DOIUrl":"https://doi.org/10.1038/s41598-025-94654-2","url":null,"abstract":"<p><p>In response to the relentless mutation of the coronavirus disease, current artificial intelligence algorithms for the automated diagnosis of COVID-19 via CT imaging exhibit suboptimal accuracy and efficiency. This manuscript proposes a multi-objective optimization algorithm (MOAOA) to enhance the BiLSTM model for COVID-19 automated diagnosis. The proposed approach involves configuring several hyperparameters for the bidirectional long short-term memory (BiLSTM), optimized using the MOAOA intelligent optimization algorithm, and subsequently validated on publicly accessible medical datasets. Remarkably, our model achieves an impressive 95.32% accuracy and 95.09% specificity. Comparative analysis with state-of-the-art techniques demonstrates that the proposed model significantly enhances accuracy, efficiency, and other performance metrics, yielding superior results.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10841"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of Apple smartwatches to obtain vital signs readings in surgical patients.","authors":"Shadi Alzahrani, Mohammed Nadershah, Mohammed Alghamdi, Razan Baabdullah, Mohammed Bayoumi, Othman Bawajeeh, Abdulrhman Alghamdi, Amr Bayoumi","doi":"10.1038/s41598-024-84459-0","DOIUrl":"https://doi.org/10.1038/s41598-024-84459-0","url":null,"abstract":"<p><p>Wearable devices, such as Apple smartwatches, have been widely used for medical and healthcare purposes. Although they provide a wide array of applications, such as heart rate and oxygen saturation determination, only a few studies have demonstrated the reliability and accuracy of these devices. Hence, this study aimed to assess the reliability of the Apple smartwatch series 8 (ASWs8) in determining heart rate and oxygen saturation against conventional monitoring devices (CMD). This cross-section study encompassed a cohort of 52 patients from King Abdulaziz University Dental Hospital in Jeddah, Saudi Arabia. We collected heart rate and oxygen saturation data via the ASWs8 and CMD. Subsequently, the mean measurement of each parameter was compared and evaluated for any significant differences. The ASWs8 yielded a mean heart rate measurement of 83.04 ± 13.4 BPM, while CMD produced 82.81 ± 13.5 BPM. The mean difference stood at - 0.23 ± 0.7 BPM, with limits of agreement ranging from - 25 to 25%. No significant difference emerged in the determination of heart rate (Cronbach α = 0.999, p = 0.311). Additionally, the ASWs8 recorded an average oxygen saturation measurement of 97.10 ± 1.6%, compared to CMD's 98.23 ± 1.0%. This resulted in a mean difference of 0.74% and limits of agreement spanning from - 3 to 1%. Once again, the analysis unveiled that no statistically significant difference existed in the obtained oxygen saturation levels (Cronbach α = 0.735, p = 0.094). In this study, we have uncovered compelling evidence that the ASWs8 stands as a reliable and accurate device. It exhibits strong concordance with the CMD, rendering it suitable for continuous vital signs, particularly for heart rate and oxygen saturation. Furthermore, this device can play a pivotal role in clinical management, facilitating the early detection of abnormal physiological parameters among pre-operative patients, thereby potentially reducing hospital admissions.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10920"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing discriminatory behavior against AI and humans.","authors":"Mike Zhuang, Eliane Deschrijver, Richard Ramsey, Ofir Turel","doi":"10.1038/s41598-025-94631-9","DOIUrl":"https://doi.org/10.1038/s41598-025-94631-9","url":null,"abstract":"<p><p>Although discrimination is typically believed to occur from well-defined categories like ethnicity, disability, and sex, studies have found that discrimination persists in minimal conditions lacking such categories. Participants have been found to preferentially allocate resources based on seemingly arbitrary shared characteristics such as dot estimation choices. Here, we use a preregistered experiment (n = 500) to investigate whether humans discriminate in a similar manner when interacting with artificial intelligence (AI) agents that ostensibly made dot estimations. We hypothesized that because humans harbor prejudice against algorithms relative to other humans (otherwise known as algorithm aversion), the strength of discriminatory behavior may be greater against AI than humans. Surprisingly, we found that participants distributed resources in a similar manner, albeit unequally, to both human and AI agents. Specifically, participants favored the other agent when decisions were aligned. Our findings suggest that discriminatory behavior is less influenced by the recipient's identity and more shaped by choice congruency.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10894"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel avenue in the successful synthesis of Schiff base macromolecules via innovative plasma and classical approaches.","authors":"Rawda M Okasha, Abdel-Aleam H Mohamed, Ahmed A Elhenawy, Mosa H Alsehli, Wael H Alsaedi, Fawzia F Alblewi, Eman A Assirey, Majed O Alawad, Faizah S Aljohani, Zainab Hrytani, Israa Ibrahim, Tarek H Afifi","doi":"10.1038/s41598-025-94665-z","DOIUrl":"https://doi.org/10.1038/s41598-025-94665-z","url":null,"abstract":"<p><p>Schiff base macromolecules have been successfully synthesized, utilizing a classical chemistry route and a dielectric barrier discharge (DBD) plasma technique. The synthesis of monomeric units has been accomplished through typical reactions of aldehyde and amine functional molecules. The condensation polymerization of the Schiff base molecules has been instigated chemically, using p-toluene sulfonyl chloride in refluxed ethanol. The molecular weight of the obtained polymers was discovered to be 524, 664 and 1,503,228 for Schiff base polymers 4a and 4b, respectively. Additionally, the polymerization reactions were prompted, employing a Dielectric Barrier Discharge (DBD) atmospheric pressure air plasma technique. The DBD plasma demonstrated a very powerful routine to produce high molecular weights macromolecules with optimum condition at 5 min. duration time, which could be an ecofriendly strategy to acquire this class of materials. The new polymeric materials have been characterized utilizing FTIR and NMR spectroscopy. Moreover, the complexation of polymer 4b with various metal moieties, Ru (II), Co (II), Cu (II), and Ni (II), has been executed in order to have a comparative study of their antitumor activity against MCF-7, HCT-116, and HepG-2 cell lines. Furthermore, the density functional theory was exploited to optimize the polymers and their complexes, and their HOMO-LUMO and energy gap were calculated, which was utilized to examine the inter/intra molecular charge transfer. The molecular electrostatic potential map was similarly quantified to investigate the reactive sites that are present in the investigated molecules. The result for the docking study confirmed that these complexed polymers adopted numerous important interactions with the amino acid of the targeted enzyme.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10840"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermodynamic modeling hexamethylenetetramine adsorption on sandstone.","authors":"Munthar Kadhim Abosaoda, Bhavesh Kanabar, Abhinav Kumar, T Ramachandran, Aman Shankhyan, A Karthikeyan, Dhirendra Nath Thatoi, Iskandar Shernazarov, Irfan Ahmad, Asgar Batuli","doi":"10.1038/s41598-025-94379-2","DOIUrl":"https://doi.org/10.1038/s41598-025-94379-2","url":null,"abstract":"<p><p>Excessive water production in oil wells presents a significant operational challenge, often requiring the use of in-situ gel treatments to block water-producing zones. However, a major challenge in the effectiveness of these treatments lies in the adsorption of gelant components onto reservoir rocks during injection, which can hinder gel formation. This research presents a novel thermodynamic investigation into the adsorption behavior of HMTA, a commonly used crosslinker, on sandstone reservoir rocks. The novelty of this study is that it provides a comprehensive thermodynamic analysis of adsorption in porous media, which has been scarcely explored in the literature. Additionally, we compare the adsorption behavior across various porous media, an approach that is rare in current research. Understanding the adsorption of HMTA in sandstone reservoirs is crucial for developing more effective gelant formulations and optimizing treatment strategies to address water production issues in oil wells. The study utilized batch experiments over a temperature range of 25-80 °C to evaluate HMTA adsorption on quartz grains. The findings revealed that the adsorption process follows the Langmuir isotherm model, indicating monolayer adsorption driven primarily by hydrogen bonding. Adsorption capacity increased with temperature, ranging from 64 to 93 mg/g-rock, confirming the endothermic nature of the process. The thermodynamic analysis further revealed that the adsorption of HMTA is spontaneous, characterized by positive enthalpy (∆H° = 16.57 kJ/mol) and entropy (∆S° = 94.5 J/mol⋅K), along with negative Gibbs free energy at all tested temperatures. Core flooding experiments on sandstone cores with a 100,000 mg/L HMTA solution corroborated the batch experiment results, although lower adsorption capacities (30-54 mg/g-rock) were observed due to the complexity of the porous medium.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10839"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude and determinants of occupational exposure to blood and body fluids among physicians in a teaching hospital in northern Ethiopia.","authors":"Hayelom Weldetekle, Hale Teka, Hagos Gidey, Assefa Sharew, Mebrihit Gebremeskel, Ruta Mehari Tafere, Hailesllassie Berhe","doi":"10.1038/s41598-025-95301-6","DOIUrl":"https://doi.org/10.1038/s41598-025-95301-6","url":null,"abstract":"<p><p>Occupational exposure to blood and body fluids (BBF) poses a significant risk for transmission of blood-borne pathogens among healthcare workers, especially in low-income countries. Physicians are at higher risk due to their direct involvement in patient care. The aim of this study was to investigate the prevalence and factors associated with occupational exposure to blood and body fluid exposure among physicians in a teaching hospital in northern Ethiopia. An institutional cross-sectional study was conducted at Ayder Comprehensive Specialized Hospital from January 1-March 31, 2020. A total of 255 physicians were selected by simple randomization. Data were collected using a structured self-reported questionnaire. Descriptive statistics were used to summarize the data. Bivariate and multivariate logistic regression analyses were performed to identify factors associated with blood and body fluid exposure. Of the 255 participants, 188 (73.7%) were male, and the mean age was 28.21 years (SD ± 4.08). The prevalence of occupational exposure to blood and body fluid in the last three months was 94 (36.9%), and lifetime exposure was 210 (82.4%). Exposure was most common among residents (52.1%) and interns (35.1%). The highest exposure rates occurred in the departments of obstetrics and gynecology (30.8%) and general surgery (24.5%). Working more than 8 h per day (AOR = 4.87, 95% CI 2.46-9.63), lack of infection prevention training (AOR = 5.36, 95% CI 1.83-15.72) and inconsistent use of gloves (AOR = 3.08, 95% CI 1.69-5.61) were significantly associated with BBF exposure. Occupational exposure to blood and body fluid exposure is high among physicians, especially among residents and interns. Factors such as long working hours, lack of infection prevention training and inconsistent use of personal protective equipment contribute to this risk. Measures to provide training, ensure the availability and consistent use of personal protective equipment and manage workload are essential to reduce occupational exposure.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10853"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing thoracodorsal artery perforator flap outcomes in oncoplastic breast surgery: multidimensional assistive techniques mitigate learning curve and enhance feasibility.","authors":"Zhipeng Hong, Zhihao Li, Xinhai Zhang, Chengye Hong, Liangqiang Li, Debo Chen","doi":"10.1038/s41598-025-95073-z","DOIUrl":"https://doi.org/10.1038/s41598-025-95073-z","url":null,"abstract":"<p><p>This study aims to evaluate the feasibility and postoperative outcomes of the thoracodorsal artery perforator (TDAP) flap in oncoplastic breast surgery (OBS), incorporating multidimensional assistive techniques. We retrospectively analyzed 14 breast cancer patients treated with TDAP flap OBS from May 2020 to August 2023. Patients were divided into two groups: Group A (first 7 cases) and Group B (last 7 cases). Preoperative perforator localization was performed using color Doppler ultrasound and handheld Doppler, with intraoperative comparisons. Blood perfusion was assessed intraoperatively with indocyanine green (ICG) fluorescence imaging and postoperatively with infrared thermal (IRT) imaging. Patient satisfaction was measured using the BREAST-Q scale. Group A had longer operation times (4.05 ± 0.61 h vs. 3.27 ± 0.31 h, P = 0.011) and longer hospitalization (9.14 ± 2.27 days vs. 7.71 ± 1.60 days, P = 0.199). No flap necrosis occurred. Preoperative and intraoperative perforator positions were consistent. ICG imaging showed good flap blood supply; edge trimming improved perfusion in two cases. IRT imaging confirmed good blood perfusion in the first 3 days post-op. BREAST-Q scores for psychological health and sexual satisfaction were lower post-op (P < 0.001), but no significant differences were found in scores for chest physical health, shoulder and back physical health, or breast satisfaction. While TDAP flap surgery involves a learning curve, it is a highly feasible technique for OBS. Multidimensional assistive technologies significantly enhance preoperative perforator localization and intraoperative flap blood perfusion monitoring, thereby improving flap survival rates and patient satisfaction.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10937"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic targeting of myelinated primary afferent neurons using a new Nefh^CreERT2 knock-in mouse.","authors":"John Cy Chen, Lech Kaczmarczyk, Felipe Meira de-Faria, Marcin Szczot, Walker S Jackson, Max Larsson","doi":"10.1038/s41598-025-95874-2","DOIUrl":"https://doi.org/10.1038/s41598-025-95874-2","url":null,"abstract":"<p><p>Primary afferent neurons that convey somatosensory modalities comprise two large, heterogeneous populations: small-diameter neurons that give rise to slowly conducting unmyelinated axonal C fibers and medium-to-large diameter neurons with fast myelinated A fibers. Despite these two major groupings, tools to differentiate between unmyelinated and myelinated primary afferent fibers by genetic targeting have not been available; in particular, whereas numerous mouse driver lines exist to target different C fiber populations, genetic tools that target myelinated primary afferent populations are scarce. Here we describe a knock-in mouse line expressing tamoxifen-dependent CreERT2 under control of the Nefh gene, which encodes neurofilament heavy chain (NFH or NF200), a protein that is highly enriched in myelinated fibers. This mouse enables highly selective and efficient recombination of Cre-dependent reporters for functional and anatomical interrogation of myelinated fibers while excluding unmyelinated C fibers. In combination with other recombinase-expressing mouse lines, this genetic tool will be valuable for intersectional targeting of subpopulations of myelinated primary afferent fibers.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"10890"},"PeriodicalIF":3.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}