Scientific Reports最新文献_第5页

LASER ablation inductively coupled plasma mass spectrometry enables the recognition of new patterns in metal-related diseases. 激光消融电感耦合等离子体质谱法能够识别金属相关疾病的新模式。

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-20258-5

Pierre Allaume, Johann Le Maître, Edouard Bardou-Jacquet, Marie-Laure Island, Olivier Loreal, Martine Ropert-Bouchet, Bruno Turlin

{"title":"LASER ablation inductively coupled plasma mass spectrometry enables the recognition of new patterns in metal-related diseases.","authors":"Pierre Allaume, Johann Le Maître, Edouard Bardou-Jacquet, Marie-Laure Island, Olivier Loreal, Martine Ropert-Bouchet, Bruno Turlin","doi":"10.1038/s41598-025-20258-5","DOIUrl":"https://doi.org/10.1038/s41598-025-20258-5","url":null,"abstract":"In this proof-of-concept study, we devised a calibration method with matrix-matched samples (phantoms) and performed quantitative LASER Ablation Inductively Coupled Mass Spectrometry (LA-ICP-MS) on 16 paraffin embedded human liver samples with genetic hemochromatosis (GH) and 5 liver resection specimens with hepatocellular carcinoma arising on GH, with correlation to histology and integration into our lab's workflow. LA-ICP-MS enables easy recognition of histological structures including portal tracts, fibrous septa and centrilobular veins. Compared to adjacent non-tumoral liver, hepatocellular carcinoma presented a decreased iron concentration (p = 0.034) and no significant difference in copper concentration. This profile was similar to that of three Iron Free Foci identified on genetic hemochromatosis liver biopsies which showed decreased concentration of iron compared to the adjacent parenchyma (p = 0.013) and no significant difference in copper concentration. LA-ICP-MS outperformed Perls' stain for iron detection in liver achieving a detection limit below 1 µg.g-1 and a lateral resolution of 5 μm and can be performed on 3 μm-thick paraffin-embedded slides with few pre-analytics constraints, enabling topographical analysis and quantification, overlay with histological stains and a preservation of the histological material contrary to classic ICP-MS. This new approach opens retrospective analysis of archived histological samples and may prove a tool in the evaluation of metal-related afflictions.","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"36212"},"PeriodicalIF":3.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the morphological changes of scour hole around gabion spur dikes. 格宾丁坝冲刷孔形态变化研究。

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-20003-y

Aysar Tuama Al-Awadi, Haitham A Hussein, Alaa H Alshami, Layth Abdulameer, Ahmed N Al-Dujaili

{"title":"Investigating the morphological changes of scour hole around gabion spur dikes.","authors":"Aysar Tuama Al-Awadi, Haitham A Hussein, Alaa H Alshami, Layth Abdulameer, Ahmed N Al-Dujaili","doi":"10.1038/s41598-025-20003-y","DOIUrl":"https://doi.org/10.1038/s41598-025-20003-y","url":null,"abstract":"River banks protection is one of the most significant challenges due to the impact of flowing ‎water and the erosion caused. The accurate estimation of morphological changes due to the generated scour around environmentally friendly spurs, such as gabion spurs is crucial for sustainable and safe hydraulic design. This study aims to analyze the effect of different grades of median gravel size (dmg = 15, 27, and 45 mm, for grade 1, 2, and 3 respectively) of rectangular gabion spurs on the scour hole characteristics under clear water condition by experimental investigation. The experiments were conducted in horizontal laboratory flume with non-cohesive sand (d50 = 0.72 mm) for varied ranges of flow intensity (0.5 ≤ V/Vc ≤ 0.998) and flow depth (7 and 10 cm). For tested gabion spurs, when the size of median gravels diameter decreases, it was found that the scour hole dimensions increase ‎as intensity of flow increases. According to the experiments results, the maximum relative scour (ds/y) equals to 1.886, 1.786, and 1.657 for grade1, 2 and 3 respectively. Furthermore, a comparisons have been characterized for the effect of the influence parameters such a flow intensity, and Fraud's number on the morphological scour hole around modelled gabions spurs. According to the extracted results of the present study and based on dimensional analysis ‎technique and statistical indicators, new validated empirical formula has been presented to estimate the scour depth near gabion ‎spurs utilizing multiple nonlinear regression. Finally, findings underscore that gabion spurs with finer gravel require careful design to mitigate excessive scour, while the formula provides a practical tool for optimizing erosion control in river engineering.","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"36192"},"PeriodicalIF":3.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic impact of hand-foot skin reaction in regorafenib-treated adult-type diffuse gliomas: A multicenter Turkish Oncology Group study. regorafenib治疗的成人型弥漫性胶质瘤的手脚皮肤反应对预后的影响：一项多中心土耳其肿瘤组研究。

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-19899-3

Safa Can Efil, Burak Bilgin, Irem Bilgetekin, Kaan Helvaci, Teoman Sakalar, Erdinc Nayir, Fatma Esra Erdem Palaz, Ali Kaan Guren, Sedat Biter, Taha Koray Sahin, Ertugrul Bayram, Neyran Kertmen, Ahmet Melih Arslan, Esra Asık, Orhun Akdogan, Ozkan Alan, Evren Fidan, Ozan Yazici, Elif Sahin, Engin Kut, Ceren Mordag Cicek, Sema Turker, Nagihan Kolkiran, Gamze Gokoz Dogu, Mustafa Sahbazlar, Aziz Batu, Bilgesah Kilictas, Mesut Yilmaz, Nejat Emre Oksuz, Mehmet Artac, Sinem Akbas, Efnan Algin, Yuksel Urun, Mehmet Ali Nahit Sendur, Bulent Yalcin

{"title":"Prognostic impact of hand-foot skin reaction in regorafenib-treated adult-type diffuse gliomas: A multicenter Turkish Oncology Group study.","authors":"Safa Can Efil, Burak Bilgin, Irem Bilgetekin, Kaan Helvaci, Teoman Sakalar, Erdinc Nayir, Fatma Esra Erdem Palaz, Ali Kaan Guren, Sedat Biter, Taha Koray Sahin, Ertugrul Bayram, Neyran Kertmen, Ahmet Melih Arslan, Esra Asık, Orhun Akdogan, Ozkan Alan, Evren Fidan, Ozan Yazici, Elif Sahin, Engin Kut, Ceren Mordag Cicek, Sema Turker, Nagihan Kolkiran, Gamze Gokoz Dogu, Mustafa Sahbazlar, Aziz Batu, Bilgesah Kilictas, Mesut Yilmaz, Nejat Emre Oksuz, Mehmet Artac, Sinem Akbas, Efnan Algin, Yuksel Urun, Mehmet Ali Nahit Sendur, Bulent Yalcin","doi":"10.1038/s41598-025-19899-3","DOIUrl":"https://doi.org/10.1038/s41598-025-19899-3","url":null,"abstract":"Glioblastoma, IDH-wildtype is the most aggressive primary brain tumor in adults, and treatment options for recurrent disease are limited. Regorafenib, an oral multikinase inhibitor, has shown efficacy in glioblastoma at first recurrence, but its role in later recurrences and in other adult-type diffuse gliomas remains unclear. This multicenter retrospective study aimed to evaluate the safety and efficacy of regorafenib and to identify prognostic factors in patients with adult-type diffuse gliomas, including glioblastoma, who were treated at the second or subsequent recurrences. A total of 68 patients from 22 institutions were analyzed. The median overall survival (OS) was 3.84 months, and the median progression-free survival was 2.46 months. The objective response rate was 13%, and the disease control rate was 48%. Adverse events occurred in 80.9% of patients, most commonly fatigue, anemia, and elevated transaminases. Hand-foot skin reaction (HFSR) of any grade was observed in 36.4% of patients and was associated with significantly improved OS (HR: 0.41; p = 0.005). Regorafenib demonstrated a manageable safety profile and modest activity in this heavily pretreated population. The development of HFSR emerged as a potential prognostic marker for treatment benefit. Taken together, our findings support further exploration of regorafenib in this setting and suggest that HFSR may serve as a practical marker to guide treatment continuation.","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"36175"},"PeriodicalIF":3.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential responses of Cacao pathogens Colletotrichum gloeosporioides and Pestalotiopsis sp. to UVB 305 nm and UVC 275 nm. 可可病原菌炭疽菌（Colletotrichum gloeosporioides）和拟盘多毛菌（pstaltiopsis sp.）对UVB 305 nm和UVC 275 nm的差异响应

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-20277-2

Insuck Baek, Jae Hee Jang, Seunghyun Lim, Zhuangji Wang, Minhyeok Cha, Clint Magill, Moon S Kim, Lyndel W Meinhardt, Sunchung Park, Ezekiel Ahn

{"title":"Differential responses of Cacao pathogens Colletotrichum gloeosporioides and Pestalotiopsis sp. to UVB 305 nm and UVC 275 nm.","authors":"Insuck Baek, Jae Hee Jang, Seunghyun Lim, Zhuangji Wang, Minhyeok Cha, Clint Magill, Moon S Kim, Lyndel W Meinhardt, Sunchung Park, Ezekiel Ahn","doi":"10.1038/s41598-025-20277-2","DOIUrl":"https://doi.org/10.1038/s41598-025-20277-2","url":null,"abstract":"Sustainable control of microbial pathogens requires alternatives to chemical agents. However, the efficacy of physical methods like Ultraviolet-C (UVC) radiation is often inconsistent due to poorly understood, pathogen-specific resistance mechanisms. To address this, we investigated the differential responses of cacao-infecting fungi (Colletotrichum gloeosporioides and the more resistant Pestalotiopsis sp.) to UVB (305 nm) and UVC (275 nm) radiation. We developed an integrated framework using quantitative morphology, hyperspectral imaging (HSI), and machine learning to dissect the physiological underpinnings of UV sensitivity. UVC proved significantly more potent than UVB; for example, a 4-min UVC exposure achieved a similar level of inactivation on a sensitive isolate as a 30-min UVB exposure. After 30 min of UVC, the resistant Pestalotiopsis sp. maintained an 89% survival rate, whereas C. gloeosporioides isolates were almost completely inactivated (< 8% survival). HSI revealed that this resistance correlated with physiological stability, while sensitive isolates exhibited significant biochemical disruption. Machine learning models successfully classified isolates based on their UV-induced phenotypes with over 73% accuracy. This understanding enabled targeted strategies, such as synergistic treatment with sonication, which overcame the high resistance of Pestalotiopsis sp. Our work provides a mechanistic basis for optimizing physical pathogen controls by linking non-invasively measured physiological states to UV resistance.","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"36256"},"PeriodicalIF":3.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineered phage-silver nanoparticle complexes as a new tool for targeted therapies. 工程噬菌体-银纳米颗粒复合物作为靶向治疗的新工具。

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-05069-y

Laura Maria De Plano, Dario Morganti, Giuseppe Nicotra, Paolo Calorenni, Emanuele Luigi Sciuto, Salvatore Oddo, Sabrina Conoci

{"title":"Engineered phage-silver nanoparticle complexes as a new tool for targeted therapies.","authors":"Laura Maria De Plano, Dario Morganti, Giuseppe Nicotra, Paolo Calorenni, Emanuele Luigi Sciuto, Salvatore Oddo, Sabrina Conoci","doi":"10.1038/s41598-025-05069-y","DOIUrl":"https://doi.org/10.1038/s41598-025-05069-y","url":null,"abstract":"The emergence of antibiotic-resistant bacteria underscores the need for innovative and precise therapeutic strategies. Here, we present a novel approach to combating bacterial infections by developing engineered phage-silver nanoparticle (AgNP) complexes as targeted therapeutic agents. We first synthesized and characterized AgNPs using advanced techniques, ensuring precise particle size and surface charge control. Subsequently, we combined the AgNPs with engineered M13 bacteriophages (Li5 phage) displaying a foreign peptide that provides selectivity for specific E. coli strains. We found that the AgNP@Li5 phage molecular complex exhibited highly selective antibacterial activity against E. coli F+, F- and pathogenic O157:H7 strains while having little impact on other bacterial species (p < 0.0001). AgNPs@Li5 demonstrated antibacterial activity with similar MIC values for E. coli TG1 and E. coli F-, inhibiting bacterial growth at a 1:16 dilution. In contrast, the antibacterial activity against E. coli O157:H7 was lower, with a dilution value of 1:8, compared to the other E. coli strains. The specificity of this approach minimizes collateral damage to surrounding bacteria, addressing a key challenge in conventional antimicrobial therapies. This system can be easily customized to target pathogens and tumors by simply modifying the peptides displayed on the phages. Our findings highlight the potential for innovative approaches in targeted therapy.","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"36135"},"PeriodicalIF":3.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Publisher Correction: Ultrasonographic evaluation of testicular and Pampiniform plexus characteristics in young bulls under different microclimatic conditions in a tropical environment. 出版者更正：在不同的小气候条件下，在热带环境下的年轻公牛睾丸和Pampiniform丛特征的超声评价。

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-23509-7

Joedson Dantas Gonçalves, Alexandre Rossetto Garcia, Rubens Paes de Arruda, José Ricardo Macedo Pezzopane, Felipe Tonato, Alda Juliana Castro de Sousa, Lívia Ferreira Pinho, Veronica Schinaider do Amaral Pereira, Gabriel Brun Vergani, Maria Emilia Franco Oliveira

引用次数: 0

Effects of manure application on paddy soil phosphorus in China based on a meta-analysis. 施肥对中国水稻土磷影响的meta分析

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-20125-3

Shuangfeng Liu, Chaoyang Liang, Jintian Zhang, Siying Chen, Jian Cheng, Minghui Chang, Jinling Xu

{"title":"Effects of manure application on paddy soil phosphorus in China based on a meta-analysis.","authors":"Shuangfeng Liu, Chaoyang Liang, Jintian Zhang, Siying Chen, Jian Cheng, Minghui Chang, Jinling Xu","doi":"10.1038/s41598-025-20125-3","DOIUrl":"https://doi.org/10.1038/s41598-025-20125-3","url":null,"abstract":"Limited phosphorus (P) availability in paddy soil significantly constrains rice growth, which can be enhanced by manure amendments. Although the effects of manure on paddy soil P fractions and availability have been extensively studied, different studies have yielded inconsistent results. Therefore, we conducted a meta-analysis of 1,799 published experimental datasets from 58 references. The results demonstrated that manure application increased the total, available, and microbial biomass P (MBP) by 46%, 134%, and 78%, respectively. The enhancing effect of manure on different P fractions followed the order of labile-P (221%) > moderately labile-P (145%) > stable-P (53%). Manure also significantly enhanced the activity of soil phosphatase, particularly that of alkaline phosphatase, by improving soil properties and enhancing microbial activities. In terms of manure types, pig manure could more significantly enhance the soil P availability and labile-P. Soil available potassium (AK), soil total nitrogen (TN), and mean annual temperature (MAT) were significant factors influencing soil P availability. Compared with non-fertilization treatments, manure amendments also significantly increased TP loss. Under application rates of 2-6 t ha- 1 yr- 1, the runoff loss of TP (101%, 95% CI: 45 to 158%) was minimized. Overall, this study recommends applying pig manure at a rate of 2-6 t ha- 1 yr- 1 in southern China's paddy soils to enhance soil P utilization efficiency and reduce P runoff loss. These findings provide valuable insights for optimizing fertilizer application strategies to enhance soil P utilization and promote sustainable agricultural development.","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"36272"},"PeriodicalIF":3.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stability analysis of a tunnel face reinforced with bolts considering the intermediate principal stress component. 考虑中间主应力分量的巷道锚杆加固工作面稳定性分析。

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-20029-2

Kai Xu, Xiang Chen, Gaofeng Luo, Xuebing Hu, Yong Li, Feng Dai, Junchao Chen

{"title":"Stability analysis of a tunnel face reinforced with bolts considering the intermediate principal stress component.","authors":"Kai Xu, Xiang Chen, Gaofeng Luo, Xuebing Hu, Yong Li, Feng Dai, Junchao Chen","doi":"10.1038/s41598-025-20029-2","DOIUrl":"https://doi.org/10.1038/s41598-025-20029-2","url":null,"abstract":"The stability of the tunnel face during excavation is a critical issue in tunnel construction. Traditional methods have offered various approaches for analyzing tunnel face stability but often neglect complex factors such as the intermediate principal stress. The mechanical behavior of rocks, however, is strongly influenced by the intermediate principal stress. This paper investigates the effectiveness of bolt reinforcement and pre-grouting techniques in enhancing tunnel face stability. A comprehensive 3D model is developed to incorporate the intermediate principal stress with Mogi Coulomb criterion to assess the impact of these reinforcement methods. Our findings suggest that the critical bolt reinforcement length ranges from [Formula: see text] (tunnel diameter) to [Formula: see text], significantly reducing extrusion deformation and enhancing tunnel stability. Pre-grouting improves the cohesion and strength of the surrounding rock, effectively preventing seepage and collapse. The safety factor obtained from the model calculations shows that SF increases with the increase of the intermediate principal stress coefficient, reaching its maximum value when the coefficient is 0.5, and then decreases. The reliability and practical applicability of our proposed model are validated through a comparative analysis with classical models. This research could provide essential guidelines for optimizing tunnel face reinforcement strategies, ensuring safer and more efficient tunneling operations.","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"36177"},"PeriodicalIF":3.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural damage detection using voting ensemble of fine-tuned convolutional neural networks and time-frequency images. 基于精细卷积神经网络和时频图像投票集合的结构损伤检测。

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-19933-4

Hessam Amanollah, Reza Karami Mohammadi, Amir K Ghorbani-Tanha

{"title":"Structural damage detection using voting ensemble of fine-tuned convolutional neural networks and time-frequency images.","authors":"Hessam Amanollah, Reza Karami Mohammadi, Amir K Ghorbani-Tanha","doi":"10.1038/s41598-025-19933-4","DOIUrl":"https://doi.org/10.1038/s41598-025-19933-4","url":null,"abstract":"Investigating the recorded response of a structure to dynamic loads is an efficient method for understanding and describing its current status. In the present paper, the ability of different Convolutional Neural Network (CNN) algorithms using time-frequency images and the performance of a voting ensemble of the models have been investigated in classifying various types of structural damage. The time-frequency images fed into CNNs were generated from acceleration responses obtained from undamaged and damaged conditions of experimental and real-world structures. The structural damages considered in the case studies encompassed various types, severities, and locations, highlighting the variation in the damaged conditions. The findings indicated that employment of a soft voting ensemble learning method, with an average prediction accuracy of 98.5%, Yielded appropriate outcomes. Moreover, in the evaluation of different CNN architectures assessed, DenseNet-based models exhibited superior performance in three distinct considered structures, while VGG-based models exhibited the highest performance across all CNNs in one specific case study focused on the location of damages, respectively. Additionally, an examination was carried out to evaluate the impact of factors that could influence the prediction accuracy of the algorithms. The results showed that increasing the duration of each acceleration record led to an improvement in the final accuracy by about 4% in the investigated structure. Furthermore, the usage of Bump mother wavelet gave rise to the highest performance.","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"36199"},"PeriodicalIF":3.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The variational modulus density theory explains mechanical responses of cell membranes and membrane crosslinkers. 变分模量密度理论解释了细胞膜和膜交联剂的力学响应。

IF 3.9 2区综合性期刊

Scientific Reports Pub Date : 2025-10-16 DOI: 10.1038/s41598-025-17573-2

Jichul Kim

引用次数: 0