Amr H Abdallah, Nesrine Ebrahim, Samar Saeed, Ahmed N Abdallah, Samar H Elsharkawy, Ahmed I Abdelgalil, Wahid S El Ghoul, Yasser M A Mohamed, Ashraf A Shamaa
{"title":"Implementation of nanographene oxide combined with mineral trioxide aggregate and hydroxyapatite biopolymer in regeneration of critical-sized bone defect in rats.","authors":"Amr H Abdallah, Nesrine Ebrahim, Samar Saeed, Ahmed N Abdallah, Samar H Elsharkawy, Ahmed I Abdelgalil, Wahid S El Ghoul, Yasser M A Mohamed, Ashraf A Shamaa","doi":"10.1038/s41598-025-17233-5","DOIUrl":"https://doi.org/10.1038/s41598-025-17233-5","url":null,"abstract":"","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32494"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Doaa Shahin, Amira M Tawfeek, Omnia Khaled, Metwaly I Mortada
{"title":"Internal quality assessment of blood components at Mansoura university blood transfusion center.","authors":"Doaa Shahin, Amira M Tawfeek, Omnia Khaled, Metwaly I Mortada","doi":"10.1038/s41598-025-17334-1","DOIUrl":"https://doi.org/10.1038/s41598-025-17334-1","url":null,"abstract":"<p><p>In modern blood banking, quality control of blood products ensures the timely availability of a blood component of high-quality yield with maximum efficacy and minimal risk to potential recipients. A prospective cross-sectional study was carried out at Mansoura University Hospital Blood Bank (MUHBB) aiming to assess the internal quality control (IQC) of 300 units of each blood components, red blood cell concentrates (RBCs), fresh frozen plasma (FFP), and platelet concentrates (PCs), and to explore their compliance with The Egyptian National Blood Transfusion Services (NBTS ),The American Association of Blood Banks (AABB), and Council of Europe (CE) standard criteria. IQC of different blood products was accepted if > 90% of units were fulfilled the standard requirements. The results of our study show that the total compliance of RBCs was 93.3% according to NBTS and CE standards and 96% as regards AABB standards. The total compliance of FFP was 94.0% according to NBTS and CE standards and 96.0% as regards AABB standards. While the total compliance of PCs was 96.0% according to NBTS and AABB standards and 93.3% as regards CE standards. Continuous improvement is recommended to decrease the percentage of noncompliance in the QC parameters included in our study and to uplift the blood transfusion practices.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32501"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rania Rashad Omar Omar Taha, Amir Hafez Ibrahim, Shereen Hafez Ibrahim
{"title":"In vitro assessment of fracture resistance of premolar teeth restored with diatomite zirconia versus barium glass filled resin composite.","authors":"Rania Rashad Omar Omar Taha, Amir Hafez Ibrahim, Shereen Hafez Ibrahim","doi":"10.1038/s41598-025-17036-8","DOIUrl":"https://doi.org/10.1038/s41598-025-17036-8","url":null,"abstract":"<p><p>Evaluate the fracture resistance of premolar teeth with MOD cavities restored with Diatomite Zirconia/Silica Filled Resin Composite Versus Barium Glass/Yetterbium Fluoride Filled resin composite systems. A 40 maxillary premolar were divided equally into four main groups (10 teeth each); a positive control group of unprepared teeth and a negative control group with prepared and unrestored MOD cavity. While the two other restored groups in which teeth with prepared MOD cavities were restored either with Diatomite Zirconia/Silica Filled Resin Composite (Zircon Fill composite, ZF) or Barium Glass/Yetterbium Fluoride Filled resin composite (Neo Spectra Composite, NS). A standardized MOD cavity was prepared in premolar teeth. Teeth were restored according to the corresponding group, and then exposed to thermocycling prior fracture resistance tested. Data collected from fracture resistance and failure mode were collected and statistically analyzed with ANOVA test. The significance level was set at p < 0.05 within all tests. There was a significant difference between different tested groups, with prepared teeth having significantly lower fracture resistance than sound teeth and samples restored with both restorative materials (p < 0.001). For Neo Spectra, most samples had mixed while Zirconfil were either had adhesive or cohesive failures with no statistically significant difference (p = 0.077). All the associations between fracture resistance and failure modes were not statistically significant. The two tested resin composites exhibited similar fracture resistance to each other and to sound teeth. Diatomite Zirconia/Silica Filled Resin Composite versus Barium Glass/Yetterbium Fluoride Filled resin composite systems were able to reinforce and restore the strength properties of the tooth.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32438"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Securely stressed: association between attachment and empathic stress in romantic couples.","authors":"Mathilde Gallistl, Lydia Handke, Melanie Kungl, Sandra Gabler, Ilona Croy, Pascal Vrticka, Veronika Engert","doi":"10.1038/s41598-025-13970-9","DOIUrl":"https://doi.org/10.1038/s41598-025-13970-9","url":null,"abstract":"<p><p>Stress-related disorders are common in modern societies. What adds to the burden is empathic stress, arising when observing another's stress elicits a stress response in the observer. In romantic couples, we investigated the association between empathic stress and adult attachment-a deep emotional bond between partners-to understand its inherent facets of risk and resilience. Psychosocial stress was induced in one partner (\"target\") while the other passively observed the situation (\"observer\"). Stress reactivity was measured in both partners via salivary cortisol, heart rate, high-frequency heart rate variability, and questionnaires. Observers' attachment representations were assessed using the Adult Attachment Interview. We found higher cortisol resonance-that is, proportionality in stress reactivity in targets and observers-in dyads with securely as opposed to insecurely attached (specifically insecure-dismissing) observers. Consistent with attachment as a resilience factor, our results suggest that securely attached individuals are physiologically more in tune with their partners during psychosocially stressful situations, possibly allowing for mutual understanding and triggering supportive behavior. However, suggesting a potential risk inherent to attachment security, in contexts of frequent or extreme partner stress, securely attached individuals may also be prone to excessive empathic stress activation and subsequent health impairments.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32420"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samah A M Abou-Alfitooh, Ammona S Mohamed, Fatma M Abdelhafiz, Ahmed Zahran, R Hosny
{"title":"Enhanced oil recovery from sandstone reservoir using cationic hyperbranched polyamidoamine dendrimer surfactant flooding under real reservoir conditions.","authors":"Samah A M Abou-Alfitooh, Ammona S Mohamed, Fatma M Abdelhafiz, Ahmed Zahran, R Hosny","doi":"10.1038/s41598-025-17757-w","DOIUrl":"https://doi.org/10.1038/s41598-025-17757-w","url":null,"abstract":"","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32509"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cemre Su Kaya Keles, Jennifer Hiller, Manuela Zimmer, Filiz Ates
{"title":"In vivo tibialis anterior muscle mechanics through force estimation using ankle joint moment and shear wave elastography.","authors":"Cemre Su Kaya Keles, Jennifer Hiller, Manuela Zimmer, Filiz Ates","doi":"10.1038/s41598-025-18292-4","DOIUrl":"https://doi.org/10.1038/s41598-025-18292-4","url":null,"abstract":"<p><p>Understanding how individual muscles contribute to joint mechanics is crucial for biomechanics. This study investigated the tibialis anterior (TA) shear modulus using shear wave elastography (SWE) and studied its relationship with ankle angle, contraction intensity, and joint moment-derived TA force and stress. Fourteen healthy volunteers (seven females, 26.43 ± 3.67 years) participated. SWE from TA, EMG, and ankle joint moment data were collected across ankle angles (- 15° dorsiflexion to 45° plantar flexion) during rest, maximum voluntary contraction (MVC), and isometric submaximal contractions. TA muscle length, passive ankle joint moment, and TA passive shear modulus increased with increasing plantar flexion (p < 0.001). During MVC, ankle joint moment peaked at 15° (50.13 Nm ± 15.54 Nm) whereas shear modulus remained unchanged (122.96 ± 9.87 kPa) across muscle lengths (p = 0.068). SWE reflected contractions at 25%, 50%, and 75% MVC (p < 0.001). TA force estimates peaked between 15° and 30°, with no significant decrease beyond this range. While SWE captured length-dependent passive properties and contraction intensity changes, the shear modulus at MVC (a stiffness measure obtained from SWE) did not align with the tangent modulus (derived from joint-moment-based force-length characteristics). Emphasizing the need for validation, SWE could serve as a valuable tool for understanding muscle mechanics and muscles' roles in joint dynamics.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32461"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Boglárka Balogh, Marietta Zille, Gergely Szarka, Loretta Péntek, Anett Futácsi, Béla Völgyi, Tamás Kovács-Öller
{"title":"Correction: Local microglial activation induced and labeled in the retina in a novel subretinal hemorrhage mouse model.","authors":"Boglárka Balogh, Marietta Zille, Gergely Szarka, Loretta Péntek, Anett Futácsi, Béla Völgyi, Tamás Kovács-Öller","doi":"10.1038/s41598-025-18785-2","DOIUrl":"https://doi.org/10.1038/s41598-025-18785-2","url":null,"abstract":"","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32516"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monerah S M Alqahtani, Amal K Elshahawi, Sameh M H Khalaf
{"title":"Projecting the global spread of xylella fastidiosa under climate change using maxent modeling.","authors":"Monerah S M Alqahtani, Amal K Elshahawi, Sameh M H Khalaf","doi":"10.1038/s41598-025-18286-2","DOIUrl":"https://doi.org/10.1038/s41598-025-18286-2","url":null,"abstract":"<p><p>Xylella fastidiosa, a virulent plant pathogen native to the Americas, presents considerable risks to economically valuable crops and ornamental flora. It is a highly virulent bacterium that causes the most critical plant infections. Many regions around the world such as the European Union countries posed the strongest constraints to prevent the introduction and spread of Xylella fastidiosa, including obligatory surveillance, and removal measures for new outbreaks. This research utilizes Geographic Information Systems (GIS) and maximum entropy modeling (Maxent) to forecast the worldwide dissemination of Xylella fastidiosa across different climate change scenarios. We gathered occurrence data from various sources, yielding 113 distinct sites, and employed 19 bioclimatic variables from the WorldClim database to ascertain four principal factors-precipitation seasonality, precipitation of the driest month, mean temperature of the warmest quarter, and minimum temperature of the coldest month-that affect habitat suitability. The Maxent model exhibited superior performance, with an Area Under the Curve (AUC) of 0.91 and a True Skill Statistic (TSS) of 0.66, signifying its efficacy in forecasting suitable environments. Current distribution maps indicate high-risk areas predominantly in subtropical and tropical regions, particularly in the Americas and Mediterranean Europe. Forecasts for 2050 and 2070 based on Representative Concentration Pathways (RCP) suggest a significant expansion of these high-risk areas, implying that climate change may intensify the proliferation of this pathogen especially under elevated emissions scenarios. These findings highlight the critical necessity for proactive management techniques to alleviate the dangers associated with Xylella fastidiosa, protecting global agricultural systems and biodiversity.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32460"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Sobczak, Tineke Steiger, Marthe Mieling, Nico Bunzeck
{"title":"Curiosity and surprise differentially affect memory depending on age.","authors":"Alexandra Sobczak, Tineke Steiger, Marthe Mieling, Nico Bunzeck","doi":"10.1038/s41598-025-14479-x","DOIUrl":"https://doi.org/10.1038/s41598-025-14479-x","url":null,"abstract":"<p><p>State and trait epistemic curiosity can promote various aspects of cognition and behavior. However, possible age-related changes, a link to surprise, and formal education remain understudied. In three behavioral experiments, with n = 54 in experiment 1, n = 81 in experiment 2, and n = 196 in experiment 3, we could show that state but not trait epistemic curiosity drives long-term memory for relevant information in young and healthy older adults (experiment 1 and 2). This effect was further modulated by surprise in young but less in older adults, which is compatible with predictive coding theories and the notion of a quadratic effect of arousal on cognition that vanishes with age (experiment 2). Finally, in a mediation model, state epistemic curiosity could be predicted directly from trait epistemic curiosity and indirectly via formal education (experiment 3). Our findings specify how state and trait curiosity, together with surprise, promote learning and facilitate knowledge acquisition across the adult lifespan.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32423"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Hany, Bart Torensma, Mahmoud Ibrahim, Mohamed N Roushdy, Anwar Ashraf Abouelnasr, Hebaallah Mohamed Zaki Jaheen, Hala M Demerdash
{"title":"Serum lncRNA-ANRIL and creatinine clearance as cardiovascular risk factors in patients who underwent sleeve gastrectomy.","authors":"Mohamed Hany, Bart Torensma, Mahmoud Ibrahim, Mohamed N Roushdy, Anwar Ashraf Abouelnasr, Hebaallah Mohamed Zaki Jaheen, Hala M Demerdash","doi":"10.1038/s41598-025-17222-8","DOIUrl":"https://doi.org/10.1038/s41598-025-17222-8","url":null,"abstract":"<p><p>Carotid intima-media thickness (CIMT) is a widely recognized marker of subclinical atherosclerosis. Emerging evidence suggests that long non-coding RNAs (lncRNAs), such as ANRIL, may contribute to the development of vascular disease through their roles in inflammation and endothelial dysfunction. We conducted a prospective study involving 93 patients undergoing sleeve gastrectomy. We assessed preoperative and postoperative levels of serum ANRIL and creatinine clearance using the Cockcroft-Gault and Jelliffe formulas. CIMT was measured via duplex ultrasound before surgery and six months postoperatively. We analyzed correlations between changes in ANRIL, renal clearance, and CIMT. Receiver Operating Characteristic (ROC) curves were used to evaluate the diagnostic performance of these markers. Postoperative serum ANRIL levels decreased significantly and were positively associated with reductions in CIMT. Both pre- and postoperative ANRIL levels showed moderate predictive value for CIMT ≥ 1 mm, with an AUC of 0.72 (95% CI 0.61-0.82). Creatinine clearance, calculated by either method, showed lower diagnostic accuracy. This study highlights the potential role of serum lncRNA ANRIL as a biomarker of early vascular improvement following metabolic surgery. Its association with CIMT suggests a link between adipose tissue remodeling and subclinical atherosclerosis regression. However, given CIMT's moderate predictive value, these findings should be considered exploratory. Further research is needed to determine ANRIL's clinical utility in cardiometabolic risk stratification.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"32493"},"PeriodicalIF":3.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}