Qi Zhong, Zidi Zhai, Zi'ang Wu, Yingyi Shen, Fang Qu, Yaqin Wu, Ziyuan Zhu, Chun Xu
{"title":"Thread design optimization of a dental implant using explicit dynamics finite element analysis.","authors":"Qi Zhong, Zidi Zhai, Zi'ang Wu, Yingyi Shen, Fang Qu, Yaqin Wu, Ziyuan Zhu, Chun Xu","doi":"10.1038/s41598-025-08858-7","DOIUrl":null,"url":null,"abstract":"<p><p>To optimize the thread design of a commercial dental implant for ideal stress distribution in the peri-implant bone. The models of the BLT<sup>®</sup> Φ4.1 × 10 implant (Institut Straumann AG) and the alveolar bone were created. Dynamic von Mises stress (σ<sub>vM</sub>) in the peri-implant cortical bone during and immediately after implantation was calculated using explicit dynamics finite element analysis (EDFEA). The combination of thread pitch, depth, tip width (TW), and coronal/apical surface angle (CSA/ASA), which produced minimal σ<sub>vM</sub> was determined as the optimal thread design by orthogonal experimental design. The implants with optimal and original thread designs were fabricated and implanted into rabbits' tibias. Implant stability quotient (ISQ), bone-to-implant contact (BIC), and bone volume fraction in 500 μm (BV/TV-500) and 1000 μm range (BV/TV-1000) were measured to evaluate the osseointegration performance of the implants. The implant thread design of 0.8-mm pitch, 0.2-mm depth, 0.15-mm TW, 10-degree CSA, and 10-degree ASA produced minimal σ<sub>vM</sub> for the maxillary posterior region (OPT-max). The thread design of 1.0-mm pitch, 0.3-mm depth, 0.2-mm TW, 0-degree CSA, and 20-degree ASA produced minimal σ<sub>vM</sub> for the mandibular posterior region (OPT-man). Optimized implants showed significantly improved ISQ value (p < 0.05) 4 weeks after implantation. The BV/TV-500 and BV/TV-1000 around the OPT-max, and the BIC and BV/TV-500 around the OPT-man implant were significantly higher than those around the originally designed implant, respectively (p < 0.05). The thread design significantly affects the stress in the peri-implant bone during and immediately after the implantation. The optimal thread design based on EDFEA promoted the osteogenesis around the implant.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"23868"},"PeriodicalIF":3.9000,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227650/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scientific Reports","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1038/s41598-025-08858-7","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
To optimize the thread design of a commercial dental implant for ideal stress distribution in the peri-implant bone. The models of the BLT® Φ4.1 × 10 implant (Institut Straumann AG) and the alveolar bone were created. Dynamic von Mises stress (σvM) in the peri-implant cortical bone during and immediately after implantation was calculated using explicit dynamics finite element analysis (EDFEA). The combination of thread pitch, depth, tip width (TW), and coronal/apical surface angle (CSA/ASA), which produced minimal σvM was determined as the optimal thread design by orthogonal experimental design. The implants with optimal and original thread designs were fabricated and implanted into rabbits' tibias. Implant stability quotient (ISQ), bone-to-implant contact (BIC), and bone volume fraction in 500 μm (BV/TV-500) and 1000 μm range (BV/TV-1000) were measured to evaluate the osseointegration performance of the implants. The implant thread design of 0.8-mm pitch, 0.2-mm depth, 0.15-mm TW, 10-degree CSA, and 10-degree ASA produced minimal σvM for the maxillary posterior region (OPT-max). The thread design of 1.0-mm pitch, 0.3-mm depth, 0.2-mm TW, 0-degree CSA, and 20-degree ASA produced minimal σvM for the mandibular posterior region (OPT-man). Optimized implants showed significantly improved ISQ value (p < 0.05) 4 weeks after implantation. The BV/TV-500 and BV/TV-1000 around the OPT-max, and the BIC and BV/TV-500 around the OPT-man implant were significantly higher than those around the originally designed implant, respectively (p < 0.05). The thread design significantly affects the stress in the peri-implant bone during and immediately after the implantation. The optimal thread design based on EDFEA promoted the osteogenesis around the implant.
期刊介绍:
We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections.
Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021).
•Engineering
Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live.
•Physical sciences
Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics.
•Earth and environmental sciences
Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems.
•Biological sciences
Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.
•Health sciences
The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.