{"title":"Corrigendum to “Mechanical ventilation in special populations” [Seminars in Perinatology, 48(2), 2024, 151888]","authors":"Huayan Zhang , Martin Keszler","doi":"10.1016/j.semperi.2024.152022","DOIUrl":"10.1016/j.semperi.2024.152022","url":null,"abstract":"","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152022"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-pharmacologic and pharmacologic care of the neonate with opioid withdrawal syndrome","authors":"Kimberly Spence , Sarah Milota","doi":"10.1016/j.semperi.2024.152020","DOIUrl":"10.1016/j.semperi.2024.152020","url":null,"abstract":"<div><div>There has been a significant paradigm shift in the management of infants with NOWS to emphasizing the role of non-pharmacologic care centered on the mother-infant dyad. By promoting bonding through rooming-in, breast-feeding and skin-to skin contact in a low stimulation environment, short and long-term outcomes have dramatically improved, resulting in reduced length of stay and need for pharmacologic treatment of the newborn. This shift in care also empowers the mother and promotes bonding and attachment, providing a solid foundation for a safe discharge. When non-pharmacological treatments are not sufficient to control the infant's withdrawal symptoms then medications can be used as an adjunct, to the minimum extent necessary and should never be used in isolation of non-pharmacological interventions. Quality improvement efforts should focus on optimizing and standardizing both non-pharmacologic and pharmacologic care to best serve this population.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152020"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Addressing stigma for families affected by opioid use disorder","authors":"Nichole Nidey , Grace Gerdts , Michelle Kavouras , Davida M. Schiff","doi":"10.1016/j.semperi.2024.152018","DOIUrl":"10.1016/j.semperi.2024.152018","url":null,"abstract":"<div><div>Pregnant and parenting people with opioid use disorder commonly experience stigma, or the enactment of negative attitudes, beliefs, and stereotypes, during their pregnancy and at delivery. We will describe four different domains of stigma: self, interpersonal, structural, and policy, and discuss how they intersect to amplify the experiences of shame, anxiety, isolation, lack of trust for birthing people and parents that can contribute to the avoidance of prenatal care and substance use treatment which can impact pregnancy and infant health outcomes. We will review a case example where stigma contributed to poor care, review preferred person-first language to use when talking to and about families impacted by opioid use disorder, and describe emerging interventions to address and mitigate the effects of stigma in the perinatal setting.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152018"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond a simple cause and effect relationship: Exploring the long-term outcomes of children prenatally exposed to opioids and other substances","authors":"Ekaterina Burduli , Hendrée E Jones","doi":"10.1016/j.semperi.2024.152010","DOIUrl":"10.1016/j.semperi.2024.152010","url":null,"abstract":"<div><div>The long-term outcomes of children exposed to opioids and other substances in utero, specifically those diagnosed with Neonatal Abstinence Syndrome (NAS), present a complex interaction of different factors. First, NAS and its clinical presentation will be defined, then summarized will be an overview of NAS prevalence, recent trends, and significance of NAS in the context of the rising synthetic opioid and polysubstance use. Highlighted will also be the identified risk factors for NAS, especially regarding the role of environmental and psychosocial stressors during pregnancy. Finally, reviewed will be the existing NAS literature, including its gaps and limitations, and suggested recommendations for future research and policy considerations for improving care for children and families impacted by NAS.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152010"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of genetics in neonatal abstinence syndrome","authors":"Sarah Vernovsky , Ana Herning , Elisha M. Wachman","doi":"10.1016/j.semperi.2024.152006","DOIUrl":"10.1016/j.semperi.2024.152006","url":null,"abstract":"<div><div>Neonatal Abstinence Syndrome (NAS) after in-utero exposure to opioids remains a significant public health concern. NAS is a highly variable condition in which presentation and severity cannot be explained by clinical factors alone. Research in human subjects has identified both genetic and epigenetic associations with prenatal opioid exposure and NAS severity, including single nucleotide polymorphisms, DNA methylation differences, and gene expression modifications. Animal studies have also identified key gene pathways that are likely important contributors to NAS phenotype. The clinical significance of identified genetic associations with NAS are unclear and warrant further study to see how they could impact NAS management.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152006"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hospital sequelae, discharge, and early interventions in infants with Neonatal Opioid Withdrawal Syndrome","authors":"Frances Y. Cheng","doi":"10.1016/j.semperi.2024.152008","DOIUrl":"10.1016/j.semperi.2024.152008","url":null,"abstract":"","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152008"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pre-natal and post-natal screening and testing in neonatal abstinence syndrome","authors":"Sharon Ostfeld-Johns","doi":"10.1016/j.semperi.2024.152009","DOIUrl":"10.1016/j.semperi.2024.152009","url":null,"abstract":"<div><div>The way we enact screening for substance use during pregnancy within our healthcare systems can work by decreasing stigma, promoting engagement, and supporting people with reaching the end of their pregnancy in a manner where the newborn can be well supported. The way we enact biochemical specimen toxicology testing for substance use during pregnancy and in newborns contributes to increased stigma, disengagement from care, and potential continuation of uncontrolled substance use up until delivery such that the newborn may not be able to be well supported in the family environment. These effects are inequitably distributed, leading to worse outcomes for families of color and families living in poverty. Serial screening with a validated questionnaire starting at the first prenatal visit and continuing through the delivery hospitalization should occur and be followed up with service connections and substance use disorder diagnosis and treatment. Newborn toxicology testing as a diagnostic tool for risk of withdrawal or the etiology of potential withdrawal symptoms represents a failure in the effectiveness of compassionate communication by healthcare providers with the birthing person. Given the current level of evidence of clinical utility and the inequitable consequences specific to these tests, they are rarely needed.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152009"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review of parent and healthcare provider experiences based on approach to managing Neonatal Opioid Withdrawal Syndrome (NOWS)","authors":"Lisa M. Cleveland","doi":"10.1016/j.semperi.2024.151995","DOIUrl":"10.1016/j.semperi.2024.151995","url":null,"abstract":"<div><div>Neonatal Opioid Withdrawal Syndrome (NOWS) is a group of clinical withdrawal signs occurring in prenatally opioid-exposed newborns and manifesting as neurobehavioral dysregulation, including extreme irritability such as excessive crying, rigid muscle tone, and difficulty feeding and sleeping. One U.S. infant experiencing NOWS is born every 25 min. Clinical management of these infants has traditionally occurred in the high-acuity environment of a neonatal intensive care unit (NICU), which contributes to separation of infants from their parents and increases the likelihood of pharmacological intervention to manage withdrawal. Over the past decade, more holistic approaches, such as the Eat, Sleep, and Console method, have focused on parents’ active participation in care, rooming-in, and implementation of non-pharmacologic soothing techniques to reduce medication use, hospital length of stay, and healthcare expenditures. These distinctly different management approaches have contributed to unique experiences for parents and healthcare providers involved in infants’ care; therefore, the purpose of this paper is to review the experiences of parents and healthcare providers as they relate to management approaches for infants with NOWS.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 151995"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kia Johnson, Adam Berkwitt, Lyubina Yankova, Rachel Osborn
{"title":"Comparisons of management approaches in neonatal opioid withdrawal syndrome: The eat, sleep, console approach vs. the Finnegan approach","authors":"Kia Johnson, Adam Berkwitt, Lyubina Yankova, Rachel Osborn","doi":"10.1016/j.semperi.2024.152021","DOIUrl":"10.1016/j.semperi.2024.152021","url":null,"abstract":"<div><div>Increased incidence of Neonatal Opioid Withdrawal Syndrome has prompted innovation in assessment and management approaches. The Finnegan Approach and the Eat, Sleep, Console are the two most commonly described approaches, though they differ substantially. The goals of this review article are to describe and compare these approaches and published outcomes, including areas of uncertainty that may inform future directions.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152021"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erinma P. Ukoha (Assistant Professor) , Mishka Terplan (Medical Director)
{"title":"Treatment and decriminalization of the mother-infant dyad in perinatal opioid use disorder","authors":"Erinma P. Ukoha (Assistant Professor) , Mishka Terplan (Medical Director)","doi":"10.1016/j.semperi.2024.152005","DOIUrl":"10.1016/j.semperi.2024.152005","url":null,"abstract":"<div><div>Treatment of perinatal opioid use disorder should center the mother-infant dyad, the needs of both entities, and preservation of the relationship. The criminalization of pregnancy and substance use in pregnancy through punitive policies and legislation and the involvement of the family policing system are in direct opposition to compassionate, person-centered care and lead to worse maternal and neonatal outcomes. In this chapter, we review the history and ongoing criminalization of pregnancy and perinatal substance use disorder, explore carcerality as a barrier to dyadic care that disproportionately targets Black, Brown, and Indigenous birthing individuals, and propose solutions to decriminalize care based in abolition medicine and reproductive justice frameworks.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 1","pages":"Article 152005"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}