通过肺功能测试，延长稳定早产儿的CPAP以促进肺生长发育。

IF 3.2 3区医学 Q1 OBSTETRICS & GYNECOLOGY

Seminars in perinatology Pub Date : 2025-02-28 DOI:10.1016/j.semperi.2025.152059

Rachna R Mamidi, Cindy T McEvoy

{"title":"通过肺功能测试，延长稳定早产儿的CPAP以促进肺生长发育。","authors":"Rachna R Mamidi, Cindy T McEvoy","doi":"10.1016/j.semperi.2025.152059","DOIUrl":null,"url":null,"abstract":"Nasal continuous positive airway pressure (CPAP) is the standard of care for the acute management of preterm infants with respiratory distress, however, the optimal duration of CPAP in stable preterm infants is unknown. In utero, preclinical, and clinical data support the premise that mechanical stretch from CPAP can increase lung growth and development. This paper will review data to support this premise, studies examining weaning infants off CPAP, the current practices in the United States regarding CPAP application and duration, and clinical studies of the association of CPAP duration and subsequent lung growth and development. Pulmonary function testing will be presented as an important outcome throughout these trials.","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":" ","pages":"152059"},"PeriodicalIF":3.2000,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Extending CPAP in stable preterm infants to increase lung growth and development as measured by pulmonary function testing.\",\"authors\":\"Rachna R Mamidi, Cindy T McEvoy\",\"doi\":\"10.1016/j.semperi.2025.152059\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Nasal continuous positive airway pressure (CPAP) is the standard of care for the acute management of preterm infants with respiratory distress, however, the optimal duration of CPAP in stable preterm infants is unknown. In utero, preclinical, and clinical data support the premise that mechanical stretch from CPAP can increase lung growth and development. This paper will review data to support this premise, studies examining weaning infants off CPAP, the current practices in the United States regarding CPAP application and duration, and clinical studies of the association of CPAP duration and subsequent lung growth and development. Pulmonary function testing will be presented as an important outcome throughout these trials.\",\"PeriodicalId\":21761,\"journal\":{\"name\":\"Seminars in perinatology\",\"volume\":\" \",\"pages\":\"152059\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-02-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Seminars in perinatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.semperi.2025.152059\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in perinatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.semperi.2025.152059","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

鼻持续气道正压通气（CPAP）是急性呼吸窘迫早产儿的标准治疗方法，然而，稳定型早产儿CPAP的最佳持续时间尚不清楚。子宫内、临床前和临床数据支持CPAP机械拉伸可以促进肺生长发育的前提。本文将回顾支持这一前提的数据、检查断奶婴儿CPAP的研究、美国目前关于CPAP应用和持续时间的实践，以及CPAP持续时间与随后肺部生长发育之间关系的临床研究。在这些试验中，肺功能测试将作为一个重要的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Extending CPAP in stable preterm infants to increase lung growth and development as measured by pulmonary function testing.

Nasal continuous positive airway pressure (CPAP) is the standard of care for the acute management of preterm infants with respiratory distress, however, the optimal duration of CPAP in stable preterm infants is unknown. In utero, preclinical, and clinical data support the premise that mechanical stretch from CPAP can increase lung growth and development. This paper will review data to support this premise, studies examining weaning infants off CPAP, the current practices in the United States regarding CPAP application and duration, and clinical studies of the association of CPAP duration and subsequent lung growth and development. Pulmonary function testing will be presented as an important outcome throughout these trials.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Seminars in perinatology 医学-妇产科学

CiteScore

5.80

自引率

2.90%

发文量

审稿时长

6-12 weeks

期刊介绍： The purpose of each issue of Seminars in Perinatology is to provide authoritative and comprehensive reviews of a single topic of interest to professionals who care for the mother, the fetus, and the newborn. The journal''s readership includes perinatologists, obstetricians, pediatricians, epidemiologists, students in these fields, and others. Each issue offers a comprehensive review of an individual topic, with emphasis on new developments that will have a direct impact on their practice.