Jennifer R. Jorgensen , Molly A. Brewer , Carolyn D. Runowicz
{"title":"Ovarian cancer in pregnancy","authors":"Jennifer R. Jorgensen , Molly A. Brewer , Carolyn D. Runowicz","doi":"10.1016/j.semperi.2025.152043","DOIUrl":null,"url":null,"abstract":"<div><div>Objective: The objective of this manuscript is to review the epidemiology, diagnosis, treatment and outcomes of ovarian cancers diagnosed during pregnancy. Finding: Ovarian cancer in pregnancy, although rare, is more likely to be diagnosed early during pregnancy due to the increased use of high resolution ultrasound. Treatment will depend on a multidisciplinary team. These cancers are usually treated with surgery alone during pregnancy, optimally between 13–20 weeks to reduce the risk of miscarriage or preterm labor. Chemotherapy is usually given after delivery if appropriate to the tumor type, unless the patient has widely metastatic disease. Conclusion: The majority of ovarian cancers diagnosed during pregnancy are Stage I due to both young age and increased use of early ultrasound during pregnancy and have a better overall prognosis than the cancers detected in older women.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 2","pages":"Article 152043"},"PeriodicalIF":3.2000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in perinatology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0146000525000205","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The objective of this manuscript is to review the epidemiology, diagnosis, treatment and outcomes of ovarian cancers diagnosed during pregnancy. Finding: Ovarian cancer in pregnancy, although rare, is more likely to be diagnosed early during pregnancy due to the increased use of high resolution ultrasound. Treatment will depend on a multidisciplinary team. These cancers are usually treated with surgery alone during pregnancy, optimally between 13–20 weeks to reduce the risk of miscarriage or preterm labor. Chemotherapy is usually given after delivery if appropriate to the tumor type, unless the patient has widely metastatic disease. Conclusion: The majority of ovarian cancers diagnosed during pregnancy are Stage I due to both young age and increased use of early ultrasound during pregnancy and have a better overall prognosis than the cancers detected in older women.
期刊介绍:
The purpose of each issue of Seminars in Perinatology is to provide authoritative and comprehensive reviews of a single topic of interest to professionals who care for the mother, the fetus, and the newborn. The journal''s readership includes perinatologists, obstetricians, pediatricians, epidemiologists, students in these fields, and others. Each issue offers a comprehensive review of an individual topic, with emphasis on new developments that will have a direct impact on their practice.