Obesity Reviews最新文献

{"title":"The impact of early childhood education and care-based interventions on child physical activity, anthropometrics, fundamental movement skills, cognitive functioning, and social–emotional wellbeing: A systematic review and meta-analysis","authors":"Alice Grady,&nbsp;Rebecca Lorch,&nbsp;Luke Giles,&nbsp;Hannah Lamont,&nbsp;Amy Anderson,&nbsp;Nicole Pearson,&nbsp;Maria Romiti,&nbsp;Melanie Lum,&nbsp;Ashleigh Stuart,&nbsp;Lucy Leigh,&nbsp;Sze Lin Yoong","doi":"10.1111/obr.13852","DOIUrl":"10.1111/obr.13852","url":null,"abstract":"<p>This review assessed the effectiveness of ECEC-based interventions to improve child physical activity, and intervention impact on child weight-based anthropometrics, fundamental movement skills (FMS), cognitive functioning, and social–emotional wellbeing. Adverse effects and costs were assessed. Finch et al's 2014 systematic review was updated. Electronic databases were searched 10 September 2014 to 27 October 2022. Included studies were randomized controlled trials of ECEC interventions targeting physical activity among children aged 0–6 years. The methodological quality of studies was assessed using Cochrane's Risk of Bias tool v2. Standardized mean differences (SMD) were calculated for each outcome with meta-analysis undertaken; otherwise, findings were described narratively. Fifty-three studies were included. ECEC-based interventions were found to significantly improve child physical activity (SMD 0.193, 95% confidence interval [CI] 0.09 to 0.3; p &lt; 0.001) and FMS (SMD 0.544, 95% CI 0.1 to 0.98; p = 0.015), compared to control. Small positive, but non-significant, effects were found for weight-based anthropometrics, cognitive functioning, and social–emotional wellbeing. Few studies reported adverse effects (n = 10), and no studies reported formal economic analyses. While ECEC-based interventions can significantly improve child physical activity and FMS, further evidence of their impact on cognitive functioning, social–emotional wellbeing, and the cost-effectiveness of such interventions is required to inform policy and practice.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longer-term effects of intermittent fasting on body composition and cardiometabolic health in adults with overweight and obesity: A systematic review and meta-analysis","authors":"Mousa Khalafi,&nbsp;Aref Habibi Maleki,&nbsp;Mahsa Ehsanifar,&nbsp;Michael E. Symonds,&nbsp;Sara K. Rosenkranz","doi":"10.1111/obr.13855","DOIUrl":"10.1111/obr.13855","url":null,"abstract":"<div>\u0000 \u0000 <p>The aim of the present study was to investigate the effects of long-term intermittent fasting (IF) on body composition and cardiometabolic health in adults with overweight and obesity. PubMed, Web of Science, and Scopus were searched from inception to March 2024 to identify original randomized trials that investigated the effects of IF versus either a control diet (CON) and/or continuous caloric restriction (CR). Participants were adults with overweight and obesity and intervention durations were ≥ 6 months. Overall, a total of 24 studies involving 2032 participants were included in the meta-analysis. Compared with CON, IF significantly reduced body weight [WMD: −2.84 kg], BMI [WMD: −1.41 kg.m²], fat mass [WMD: −3.06 kg], fat-free mass [WMD: −0.81 kg], waist circumference [WMD: −3.85 cm], visceral fat [SMD: −0.37], fasting glucose [WMD: −0.14 mmol/l], triglycerides [WMD: −0.12 mmol/l], and diastolic blood pressure [WMD: −2.24 mmHg]. Conversely, IF significantly increased high-density lipoproteins [WMD: 0.04 mmol/l] when compared with CON, but had no effects on insulin, hemoglobin A1c%, total cholesterol, low-density lipoprotein, or systolic blood pressure. Compared with CR, IF significantly reduced fat mass [WMD: −0.70 kg], body fat percentage [WMD: −0.59%], and DBP [WMD: −0.91 mmHg], and increased HDL [WMD: 0.03 mmol/l], with no other significant effects. Subgroup analyses showed that the mode of IF and intervention duration were the primary moderators of IF effects on the markers. In adults with overweight or obesity, IF and CR are comparably effective for reducing body weight and adiposity, as well as for improving cardiometabolic health markers.</p>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying behavior change techniques (BCTs) in responsive feeding interventions to prevent childhood obesity—A systematic review","authors":"Gráinne Máire Áine Ní Eidhin,&nbsp;Karen Matvienko-Sikar,&nbsp;Sarah Anne Redsell","doi":"10.1111/obr.13857","DOIUrl":"10.1111/obr.13857","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Complex interventions that include responsive infant feeding components can potentially prevent childhood obesity. To develop a replicable responsive feeding intervention, an understanding of the most effective behavior change techniques (BCTs) and theory is needed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To identify the BCTs and theories used in interventions with responsive feeding components for caregivers of children ≤2 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>PsycINFO, CINAHL, Cochrane Library, EMBASE, and MIDIRS were searched from inception to May 2023. Studies of obesity prevention interventions with a responsive feeding component were included. BCT Taxonomy Version 1 and Michie and Prestwich theory coding method were applied.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Findings</h3>\u0000 \u0000 <p>Eighteen interventions were identified; the number of BCTs ranged from 3 to 11 (mean = 5.5). The most used BCTs were “Instruction on how to perform a behaviour” (17/18) and “Adding objects to the environment” (13/18), which were commonly used in the nine trials demonstrating higher responsive feeding behaviours and the four trials reporting reduced likelihood of overweight or obesity, or rapid weight gain. Fifteen trials reported use of theory.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>BCT use was low in interventions with responsive feeding components. BCTs are replicable; their use in interventions, alongside theory, will ensure that key determinants of responsive feeding behavior are included in future obesity prevention interventions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of mindfulness-based interventions on obesogenic eating behaviors: A systematic review and meta-analysis","authors":"Tsui-Sui Annie Kao,&nbsp;Jiying Ling,&nbsp;Mohammed Alanazi,&nbsp;Ahmed Atwa,&nbsp;Stephanie Liu","doi":"10.1111/obr.13860","DOIUrl":"10.1111/obr.13860","url":null,"abstract":"<p>This systematic review and meta-analysis examined the effects of mindful-based interventions (MBIs) on changes in obesogenic eating behaviors. Seven databases (CINAHL, PubMed, PsycINFO, Cochrane, Web of Science Core Collection, Embase, Sociological Abstracts) were searched. Random-effects models were performed to estimate the pooled effects, and mixed-effects models were used to explore potential moderators of MBIs on eating behavioral changes. The significant effects on mindless eating habits included controlled eating (Hedge's g = 0.23, <i>p</i> = 0.005), external eating (g = −0.62, <i>p</i> = 0.001), fullness awareness (g = 0.64, <i>p</i> &lt; 0.001), hunger eating (g = −0.69, <i>p</i> = 0.032), energy intake (g = −0.60, <i>p</i> = 0.003), sweet intake (g = −0.39, <i>p</i> &lt; 0.001), and impulsive food choice (g = −0.43, <i>p</i> = 0.002). However, small and insignificant effects were noted for stress-related eating habits like emotional eating (g = −0.27; <i>p</i> = 0.070) and binge eating (g = −0.35, <i>p</i> = 0.136). The long-term effects were significantly sustained on hunger eating (g = −0.50, <i>p</i> = 0.007) but insignificant on emotional eating (g = −0.22, <i>p</i> = 0.809). MBIs delivered in clinical settings were more effective for decreasing emotional eating compared with those in school settings. Our findings support the effectiveness of MBIs. The pooled effects on improving mindless eating habits were stronger than the modification of stress-related eating habits.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 3","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13860","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and enablers to effective weight management for people living with overweight and obesity: A rapid scoping review","authors":"Alemayehu Mekonnen,&nbsp;Vidanka Vasilevski,&nbsp;Anna Chapman,&nbsp;Shaan Naughton,&nbsp;Eva Yuen,&nbsp;Jane Willcox,&nbsp;Elizabeth Holmes-Truscott,&nbsp;Jaithri Ananthapavan,&nbsp;Fisaha Tesfay,&nbsp;Linda Sweet,&nbsp;Anna Peeters","doi":"10.1111/obr.13858","DOIUrl":"10.1111/obr.13858","url":null,"abstract":"<p>A scoping review was conducted to identify barriers and enablers to effective weight management in healthcare settings for people living with overweight and obesity in English-speaking high-income countries. Peer-reviewed and gray literature were systematically searched in June 2024. Data were analyzed using inductive thematic analysis. Of the 15,684 unique articles identified and screened for relevance, 216 studies were included. Healthcare-related barriers and enablers to weight management were organized under three themes: a) healthcare provider-related factors, b) provision of care, and c) policy/funding. Prominent barriers included healthcare provider knowledge deficits and low prioritization of obesity management, mainly in the primary care setting. Weight management beyond the primary care setting was found to be especially challenging, with poor referral pathways, service fragmentation, lack of multidisciplinary practice, and restricted eligibility criteria, hindering the accessibility of services. Developing consistent policies and guidelines, improving the education of healthcare providers, and increasing funding to provide low-cost comprehensive care, were identified as enablers to access and uptake of weight management services. Considerable overlap in the identified barriers existed across healthcare providers and settings. A whole health system approach to minimize barriers and strengthen enablers to weight management services is needed, to address rising obesity rates.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 3","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13858","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular mechanisms of the obesity associated with Bardet-Biedl syndrome: An update","authors":"Bang-Hua Zhong,&nbsp;Ning Nie,&nbsp;Ming Dong","doi":"10.1111/obr.13859","DOIUrl":"10.1111/obr.13859","url":null,"abstract":"<div>\u0000 \u0000 <p>Obesity is a prominent feature of Bardet-Biedl syndrome (BBS), which represents a major and growing public health problem. More than half of BBS patients carry mutations in one of eight genes that encode subunits of a protein complex known as the BBSome, which has emerged as a key regulator of energy and glucose homeostasis. However, the mechanisms underlying obesity in BBS are complex. Numerous studies have identified a high prevalence of insulin resistance and metabolic syndrome among individuals with BBS. However, the exact mechanisms are not fully understood. This review summarized evidence from experiments using mouse and cell models, focusing on the energy imbalance that leads to obesity in patients with BBS. The studies discussed in this review contribute to understanding the functional role of the BBSome in the obesity associated with BBS, laying the foundation for developing new preventive or therapeutic strategies for obese patients.</p>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 3","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142542413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding barriers and facilitators to lifestyle management in people with polycystic ovary syndrome: A mixed method systematic review","authors":"Margaret McGowan,&nbsp;Rhonda Garad,&nbsp;Girija Wadhwani,&nbsp;Sophia Torkel,&nbsp;Vibhuti Rao,&nbsp;Alison Maunder,&nbsp;Elaine K. Osei-Safo,&nbsp;Lisa J. Moran,&nbsp;Stephanie Cowan","doi":"10.1111/obr.13854","DOIUrl":"10.1111/obr.13854","url":null,"abstract":"<div>\u0000 \u0000 <p>Polycystic ovary syndrome (PCOS) is an endocrine disorder affecting 10–13% of reproductive-aged women. Lifestyle management through diet and physical activity changes can improve reproductive, metabolic, and psychological comorbidities. The aim of this systematic review is to understand the barriers and facilitators to lifestyle changes from the perspective of people with PCOS and health care professionals (HCP) using the theoretical domains framework and capability, opportunity, motivation, and behavior model. Six databases were systematically searched for qualitative, quantitative, and mixed-methods studies to 22nd September 2022. Quantitative outcomes from quantitative and mixed-methods studies were narratively synthesized and all studies were thematically analyzed. Sixty-eight papers met the eligibility criteria. HCP education on lifestyle management in PCOS was viewed by all to be inadequate, impacting the quality of care and health outcomes. Lifestyle advice delivered by a multidisciplinary team, including dietitians, was identified as a key component for change. All agreed that there was a need for individualized and PCOS-specific lifestyle advice. Weight stigma was identified as negatively impacting both those in larger and smaller bodies with PCOS, reducing the quality of care and affecting self-perception and mental health. People with PCOS perceived that lifestyle management was overly focused on weight loss and fertility, independent of their own personal motivations and goals. Systemic changes, including increasing HCP education on lifestyle management and multidisciplinary collaboration, focusing on lifestyle advice that meets individual needs, and reducing the use of weight-centric care are necessary for long-term sustainable changes and improvements in health outcomes in people with PCOS.</p>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Branched-chain amino acid metabolism: Pathophysiological mechanism and therapeutic intervention in metabolic diseases","authors":"Shama Mansoori,&nbsp;Melody Yuen-man Ho,&nbsp;Kelvin Kwun-wang Ng,&nbsp;Kenneth King-yip Cheng","doi":"10.1111/obr.13856","DOIUrl":"10.1111/obr.13856","url":null,"abstract":"<p>Branched-chain amino acids (BCAAs), including leucine, isoleucine, and valine, are essential for maintaining physiological functions and metabolic homeostasis. However, chronic elevation of BCAAs causes metabolic diseases such as obesity, type 2 diabetes (T2D), and metabolic-associated fatty liver disease (MAFLD). Adipose tissue, skeletal muscle, and the liver are the three major metabolic tissues not only responsible for controlling glucose, lipid, and energy balance but also for maintaining BCAA homeostasis. Under obese and diabetic conditions, different pathogenic factors like pro-inflammatory cytokines, lipotoxicity, and reduction of adiponectin and peroxisome proliferator-activated receptors γ (PPARγ) disrupt BCAA metabolism, leading to excessive accumulation of BCAAs and their downstream metabolites in metabolic tissues and circulation. Mechanistically, BCAAs and/or their downstream metabolites, such as branched-chain ketoacids (BCKAs) and 3-hydroxyisobutyrate (3-HIB), impair insulin signaling, inhibit adipogenesis, induce inflammatory responses, and cause lipotoxicity in the metabolic tissues, resulting in multiple metabolic disorders. In this review, we summarize the latest studies on the metabolic regulation of BCAA homeostasis by the three major metabolic tissues—adipose tissue, skeletal muscle, and liver—and how dysregulated BCAA metabolism affects glucose, lipid, and energy balance in these active metabolic tissues. We also summarize therapeutic approaches to restore normal BCAA metabolism as a treatment for metabolic diseases.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sharing the motherload: A review and development of the CO–Parent conceptual model for early childhood obesity prevention","authors":"Konsita Kuswara,&nbsp;Vanessa A. Shrewsbury,&nbsp;Jacqui A. Macdonald,&nbsp;Alexandra Chung,&nbsp;Briony Hill","doi":"10.1111/obr.13853","DOIUrl":"10.1111/obr.13853","url":null,"abstract":"<p>Fathers remain under-represented in early childhood obesity prevention research and interventions, despite growing evidence that paternal biopsychosocial factors and behaviors from pre- and post-conception can influence lifelong offspring health. Informed by a literature review of high-quality evidence, “CO–Parent” (childhood obesity–Parent) is a new conceptual model underpinned by couple interdependence theory and a socioecological framework. Literature was searched for the concepts parental AND weight-related behaviors AND child weight or weight-related behaviors, in databases including MEDLINE, PsycINFO, Global Health, Scopus, and SocINDEX. Prior evidence syntheses were prioritized as source data to inform model development. “CO–Parent” illustrates the interdependent and independent effects of maternal and paternal weight, weight-related behaviors, and well-being, across preconception, pregnancy, postpartum, and the early years on child weight-related behaviors and weight up to age five. The influences of public policy, social, environmental, economic, community, and other complex modifiable mediating factors are included in the model. The “CO–Parent” conceptual model paves the way for a paradigm shift by recognizing fathers as key figures in early childhood obesity prevention initiatives, encouraging them to “share the motherload.” It highlights both the independent and interdependent roles fathers play in the epidemiology of obesity starting from preconception. CO–Parent also provides the foundations necessary to guide future theory and research to be more inclusive of fathers to further understanding of the independent and interdependent influences of parents in early childhood obesity prevention.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Core set of patient-reported outcome measures to measure quality of life in obesity treatment research","authors":"Phillip J. Dijkhorst,&nbsp;Claire E. E. de Vries,&nbsp;Caroline B. Terwee,&nbsp;Ignace M. C. Janssen,&nbsp;Ronald S. L. Liem,&nbsp;Bart A. van Wagensveld,&nbsp;Johan Ottosson,&nbsp;Bruno Halpern,&nbsp;Stuart W. Flint,&nbsp;Elisabeth F. C. van Rossum,&nbsp;Alend Saadi,&nbsp;Lisa West-Smith,&nbsp;Mary O'Kane,&nbsp;Jason C. G. Halford,&nbsp;Karen D. Coulman,&nbsp;Salman Al-Sabah,&nbsp;John B. Dixon,&nbsp;Wendy A. Brown,&nbsp;Ximena Ramos Salas,&nbsp;Maarten M. Hoogbergen,&nbsp;Sally Abbott,&nbsp;Alyssa J. Budin,&nbsp;Jennifer F. Holland,&nbsp;Lotte Poulsen,&nbsp;Richard Welbourn,&nbsp;Bernardo Rea Ruanova,&nbsp;John M. Morton,&nbsp;Francois Pattou,&nbsp;Erman O. Akpinar,&nbsp;Stephanie Sogg,&nbsp;Jacques M. Himpens,&nbsp;Vanessa Osborne,&nbsp;Natasja Wijling,&nbsp;Laura Divine,&nbsp;Nadya Isack,&nbsp;Susie Birney,&nbsp;J. M. Bernadette Keenan,&nbsp;Joe Nadglowski,&nbsp;Jacqueline Bowman,&nbsp;Ken Clare,&nbsp;Riccardo Meloni,&nbsp;Sandra de Blaeij,&nbsp;Theodore K. Kyle,&nbsp;Melanie Bahlke,&nbsp;Andrew Healing,&nbsp;Ian Patton,&nbsp;Valerie M. Monpellier","doi":"10.1111/obr.13849","DOIUrl":"10.1111/obr.13849","url":null,"abstract":"<p>The lack of standardization in patient-reported outcome measures (PROMs) has made measurement and comparison of quality of life (QoL) outcomes in research focused on obesity treatment challenging. This study reports on the results of the second and third global multidisciplinary Standardizing Quality of life measures in Obesity Treatment (S.Q.O.T.) consensus meetings, where a core set of PROMs to measure nine previously selected patient-reported outcomes (PROs) in obesity treatment research was established.</p><p>The S.Q.O.T. II online and S.Q.O.T. III face-to-face hybrid consensus meetings were held in October 2021 and May 2022. The meetings were led by an independent moderator specializing in PRO measurement. Nominal group techniques, Delphi exercises, and anonymous voting were used to select the most suitable PROMs by consensus. The meetings were attended by 28 and 27 participants, respectively, including a geographically diverse selection of people living with obesity (PLWO) and experts from various disciplines.</p><p>Out of 24 PROs and 16 PROMs identified in the first S.Q.O.T. consensus meeting, the following nine PROs and three PROMs were selected via consensus: BODY-Q (physical function, physical symptoms, psychological function, social function, eating behavior, and body image), IWQOL-Lite (self-esteem), and QOLOS (excess skin). No PROM was selected to measure stigma as existing PROMs deemed to be inadequate.</p><p>A core set of PROMs to measure QoL in research focused on obesity treatment has been selected incorporating patients' and experts' opinions. This core set should serve as a minimum to use in obesity research studies and can be combined with clinical parameters.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13849","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}