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Sharing the motherload: A review and development of the CO–Parent conceptual model for early childhood obesity prevention 分担母亲的负担:儿童早期肥胖预防的 CO-Parent 概念模型回顾与发展。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-17 DOI: 10.1111/obr.13853
Konsita Kuswara, Vanessa A. Shrewsbury, Jacqui A. Macdonald, Alexandra Chung, Briony Hill
{"title":"Sharing the motherload: A review and development of the CO–Parent conceptual model for early childhood obesity prevention","authors":"Konsita Kuswara,&nbsp;Vanessa A. Shrewsbury,&nbsp;Jacqui A. Macdonald,&nbsp;Alexandra Chung,&nbsp;Briony Hill","doi":"10.1111/obr.13853","DOIUrl":"10.1111/obr.13853","url":null,"abstract":"<p>Fathers remain under-represented in early childhood obesity prevention research and interventions, despite growing evidence that paternal biopsychosocial factors and behaviors from pre- and post-conception can influence lifelong offspring health. Informed by a literature review of high-quality evidence, “CO–Parent” (childhood obesity–Parent) is a new conceptual model underpinned by couple interdependence theory and a socioecological framework. Literature was searched for the concepts parental AND weight-related behaviors AND child weight or weight-related behaviors, in databases including MEDLINE, PsycINFO, Global Health, Scopus, and SocINDEX. Prior evidence syntheses were prioritized as source data to inform model development. “CO–Parent” illustrates the interdependent and independent effects of maternal and paternal weight, weight-related behaviors, and well-being, across preconception, pregnancy, postpartum, and the early years on child weight-related behaviors and weight up to age five. The influences of public policy, social, environmental, economic, community, and other complex modifiable mediating factors are included in the model. The “CO–Parent” conceptual model paves the way for a paradigm shift by recognizing fathers as key figures in early childhood obesity prevention initiatives, encouraging them to “share the motherload.” It highlights both the independent and interdependent roles fathers play in the epidemiology of obesity starting from preconception. CO–Parent also provides the foundations necessary to guide future theory and research to be more inclusive of fathers to further understanding of the independent and interdependent influences of parents in early childhood obesity prevention.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Core set of patient-reported outcome measures to measure quality of life in obesity treatment research 在肥胖症治疗研究中,用于衡量生活质量的一套患者报告结果核心指标。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-17 DOI: 10.1111/obr.13849
Phillip J. Dijkhorst, Claire E. E. de Vries, Caroline B. Terwee, Ignace M. C. Janssen, Ronald S. L. Liem, Bart A. van Wagensveld, Johan Ottosson, Bruno Halpern, Stuart W. Flint, Elisabeth F. C. van Rossum, Alend Saadi, Lisa West-Smith, Mary O'Kane, Jason C. G. Halford, Karen D. Coulman, Salman Al-Sabah, John B. Dixon, Wendy A. Brown, Ximena Ramos Salas, Maarten M. Hoogbergen, Sally Abbott, Alyssa J. Budin, Jennifer F. Holland, Lotte Poulsen, Richard Welbourn, Bernardo Rea Ruanova, John M. Morton, Francois Pattou, Erman O. Akpinar, Stephanie Sogg, Jacques M. Himpens, Vanessa Osborne, Natasja Wijling, Laura Divine, Nadya Isack, Susie Birney, J. M. Bernadette Keenan, Joe Nadglowski, Jacqueline Bowman, Ken Clare, Riccardo Meloni, Sandra de Blaeij, Theodore K. Kyle, Melanie Bahlke, Andrew Healing, Ian Patton, Valerie M. Monpellier
{"title":"A Core set of patient-reported outcome measures to measure quality of life in obesity treatment research","authors":"Phillip J. Dijkhorst,&nbsp;Claire E. E. de Vries,&nbsp;Caroline B. Terwee,&nbsp;Ignace M. C. Janssen,&nbsp;Ronald S. L. Liem,&nbsp;Bart A. van Wagensveld,&nbsp;Johan Ottosson,&nbsp;Bruno Halpern,&nbsp;Stuart W. Flint,&nbsp;Elisabeth F. C. van Rossum,&nbsp;Alend Saadi,&nbsp;Lisa West-Smith,&nbsp;Mary O'Kane,&nbsp;Jason C. G. Halford,&nbsp;Karen D. Coulman,&nbsp;Salman Al-Sabah,&nbsp;John B. Dixon,&nbsp;Wendy A. Brown,&nbsp;Ximena Ramos Salas,&nbsp;Maarten M. Hoogbergen,&nbsp;Sally Abbott,&nbsp;Alyssa J. Budin,&nbsp;Jennifer F. Holland,&nbsp;Lotte Poulsen,&nbsp;Richard Welbourn,&nbsp;Bernardo Rea Ruanova,&nbsp;John M. Morton,&nbsp;Francois Pattou,&nbsp;Erman O. Akpinar,&nbsp;Stephanie Sogg,&nbsp;Jacques M. Himpens,&nbsp;Vanessa Osborne,&nbsp;Natasja Wijling,&nbsp;Laura Divine,&nbsp;Nadya Isack,&nbsp;Susie Birney,&nbsp;J. M. Bernadette Keenan,&nbsp;Joe Nadglowski,&nbsp;Jacqueline Bowman,&nbsp;Ken Clare,&nbsp;Riccardo Meloni,&nbsp;Sandra de Blaeij,&nbsp;Theodore K. Kyle,&nbsp;Melanie Bahlke,&nbsp;Andrew Healing,&nbsp;Ian Patton,&nbsp;Valerie M. Monpellier","doi":"10.1111/obr.13849","DOIUrl":"10.1111/obr.13849","url":null,"abstract":"<p>The lack of standardization in patient-reported outcome measures (PROMs) has made measurement and comparison of quality of life (QoL) outcomes in research focused on obesity treatment challenging. This study reports on the results of the second and third global multidisciplinary Standardizing Quality of life measures in Obesity Treatment (S.Q.O.T.) consensus meetings, where a core set of PROMs to measure nine previously selected patient-reported outcomes (PROs) in obesity treatment research was established.</p><p>The S.Q.O.T. II online and S.Q.O.T. III face-to-face hybrid consensus meetings were held in October 2021 and May 2022. The meetings were led by an independent moderator specializing in PRO measurement. Nominal group techniques, Delphi exercises, and anonymous voting were used to select the most suitable PROMs by consensus. The meetings were attended by 28 and 27 participants, respectively, including a geographically diverse selection of people living with obesity (PLWO) and experts from various disciplines.</p><p>Out of 24 PROs and 16 PROMs identified in the first S.Q.O.T. consensus meeting, the following nine PROs and three PROMs were selected via consensus: BODY-Q (physical function, physical symptoms, psychological function, social function, eating behavior, and body image), IWQOL-Lite (self-esteem), and QOLOS (excess skin). No PROM was selected to measure stigma as existing PROMs deemed to be inadequate.</p><p>A core set of PROMs to measure QoL in research focused on obesity treatment has been selected incorporating patients' and experts' opinions. This core set should serve as a minimum to use in obesity research studies and can be combined with clinical parameters.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13849","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prognostic role of food addiction for weight loss treatment outcomes in individuals with overweight and obesity: A systematic review and meta-analysis 食物成瘾对超重和肥胖症患者减肥治疗结果的预后作用:系统回顾和荟萃分析。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-16 DOI: 10.1111/obr.13851
Georg Halbeisen, Marie Pahlenkemper, Luisa Sabel, Candice Richardson, Zaida Agüera, Fernando Fernandez-Aranda, Georgios Paslakis
{"title":"The prognostic role of food addiction for weight loss treatment outcomes in individuals with overweight and obesity: A systematic review and meta-analysis","authors":"Georg Halbeisen,&nbsp;Marie Pahlenkemper,&nbsp;Luisa Sabel,&nbsp;Candice Richardson,&nbsp;Zaida Agüera,&nbsp;Fernando Fernandez-Aranda,&nbsp;Georgios Paslakis","doi":"10.1111/obr.13851","DOIUrl":"10.1111/obr.13851","url":null,"abstract":"<p>Food addiction (FA) could be a potential prognostic factor of weight loss intervention outcomes. This systematic review with meta-analysis aimed to (1) estimate this prognostic effect of FA diagnosis and symptom count in individuals with overweight or obesity and (2) explore potential sources of heterogeneity based on properties of the weight loss intervention, study, and sample (e.g., age, gender, ethnicity). We searched PubMed, PsycINFO, and Web of Science for studies reporting on associations between pre-intervention FA (assessed with the Yale Food Addiction Scale) and weight outcomes after weight loss intervention in individuals with overweight or obesity without a medically diagnosed eating disorder. Twenty-five studies met inclusion criteria, including 4904 individuals (71% women, <i>M</i><sub>age</sub> = 41 years, BMI = 40.82 kg/m<sup>2</sup>), <i>k</i> = 18 correlations of weight loss with FA symptom count, and <i>k</i> = 21 mean differences between FA diagnosis groups. Pooled estimates of random-effects meta-analyses found limited support for a detrimental effect of FA symptom count and diagnosis on weight loss intervention outcomes. Negative associations with FA increased for behavioral weight loss interventions and among more ethnically diverse samples. More research on the interaction of FA with pre-existing mental health problems and environmental factors is needed.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causality of visceral adipose tissue on chronic kidney disease and renal function measure indicators, and mediation role of hypertension: Mendelian randomization study 内脏脂肪组织对慢性肾脏病和肾功能测量指标的因果关系及高血压的中介作用:孟德尔随机研究
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-10 DOI: 10.1111/obr.13845
Teng-Yu Gao, Jun-Chi Wang, Qi-Jian Zhao, Xiang-Ning Zhou, Yu-Ting Jiang, Lian Ren, Chao Zhang
{"title":"Causality of visceral adipose tissue on chronic kidney disease and renal function measure indicators, and mediation role of hypertension: Mendelian randomization study","authors":"Teng-Yu Gao,&nbsp;Jun-Chi Wang,&nbsp;Qi-Jian Zhao,&nbsp;Xiang-Ning Zhou,&nbsp;Yu-Ting Jiang,&nbsp;Lian Ren,&nbsp;Chao Zhang","doi":"10.1111/obr.13845","DOIUrl":"10.1111/obr.13845","url":null,"abstract":"<p>Although chronic kidney disease (CKD) is associated with obesity, few studies have used visceral adipose tissue (VAT) as an indicator to investigate its causal effect on CKD. Therefore, Mendelian randomization (MR) was employed to study the causal effects of VAT on CKD and its potential mediation by hypertension. Genome-wide association study (GWAS) statistics on VAT exposure were obtained from the UK Biobank, while GWAS datasets of CKD outcomes were obtained from CKDGen and FinnGen (validation study). Furthermore, VAT was considered the exposure, with the estimated glomerular filtration rate based on creatinine (eGFR (crea)), estimated glomerular filtration rate based on cystatin C (eGFR(cys)), and blood urea nitrogen (BUN) employed to assess the causal effect of VAT on kidney test indicators. Lastly, a two-step MR method was used to study the mediating role of hypertension in the pathogenesis of VAT among patients with CKD. VAT exhibited a positive causal association with CKD, irrespective of whether the GWAS datasets from CKDGen (odds ratio [OR] = 1.18, 95% CI: 1.08 to 1.29, P = 1.433140e−04) or FinnGen (1.47, 1.30 to 1.67, <i>p</i> = 2.500000e−09). VAT was not causally associated with eGFR (crea) (1.00, 0.99 to 1.00, <i>p</i> = 0.53), was negatively associated with eGFR (cys) (0.95, 0.93 to 0.97, P = 5.070000e−10), and was positively associated with BUN (1.02,1.01 to 1.02, P = 7.824860e−04). The mediating effect of VAT on CKD via hypertension was 45.8% (95% CI: 26.4 65.1). VAT has a positive causal effect on CKD, with hypertension playing a significant role. However, the effects of VAT on renal function indicators require further investigation.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142398864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weight/height2: Mathematical overview of the world's most widely used adiposity index 体重/身高2:世界上最广泛使用的脂肪指数的数学概述。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-10 DOI: 10.1111/obr.13842
Steven B. Heymsfield, John D. Sorkin, Diana M. Thomas, Shengping Yang, Moonseong Heo, Cassidy McCarthy, Jasmine Brown, Angelo Pietrobelli
{"title":"Weight/height2: Mathematical overview of the world's most widely used adiposity index","authors":"Steven B. Heymsfield,&nbsp;John D. Sorkin,&nbsp;Diana M. Thomas,&nbsp;Shengping Yang,&nbsp;Moonseong Heo,&nbsp;Cassidy McCarthy,&nbsp;Jasmine Brown,&nbsp;Angelo Pietrobelli","doi":"10.1111/obr.13842","DOIUrl":"10.1111/obr.13842","url":null,"abstract":"<p>A footnote in Adolphe Quetelet's classic 1835 Treatise on Man described his algebraic analysis of how body weight (\u0000<span></span><math>\u0000 <mi>W</mi></math>) varies with height (\u0000<span></span><math>\u0000 <mi>H</mi></math>) in adult males and females. Using data on 12 short and 12 tall subjects of each sex, Quetelet established the rule that \u0000<span></span><math>\u0000 <mi>W</mi></math> is approximately proportional (\u0000<span></span><math>\u0000 <mo>∝</mo></math>) to <i>H</i><sup>2</sup> in adults; that is, \u0000<span></span><math>\u0000 <mi>W</mi>\u0000 <mo>∝</mo>\u0000 <msup>\u0000 <mi>H</mi>\u0000 <mn>2</mn>\u0000 </msup></math> when \u0000<span></span><math>\u0000 <mi>W</mi>\u0000 <mo>≈</mo>\u0000 <mi>α</mi>\u0000 <msup>\u0000 <mi>H</mi>\u0000 <mn>2</mn>\u0000 </msup></math> for some constant \u0000<span></span><math>\u0000 <mi>α</mi></math>. Quetelet's Rule (\u0000<span></span><math>\u0000 <mi>W</mi>\u0000 <mo>∝</mo>\u0000 <msup>\u0000 <mi>H</mi>\u0000 <mn>2</mn>\u0000 </msup></math>), transformed and renamed in the twentieth century to body mass index (\u0000<span></span><math>\u0000 <mi>BMI</mi>\u0000 <mo>=</mo>\u0000 <mi>W</mi>\u0000 <mo>/</mo>\u0000 <msup>\u0000 <mi>H</mi>\u0000 <mn>2</mn>\u0000 </msup></math>), is now a globally applied phenotypic descriptor of adiposity at the individual and population level. The journey from footnote to ubiquitous adiposity measure traveled through hundreds of scientific reports and many more lay publications. The recent introduction of highly effective pharmacologic weight loss treatments has heightened scrutiny of BMI's origins and appropriateness as a gateway marker for diagnosing and monitoring people with obesity. This contemporary context prompted the current report that delves into the biological and mathematical paradigms that underlie the simple index \u0000<span></span><math>\u0000 <mi>BMI</mi>\u0000 <mo>=</mo>\u0000 <mi>W</mi>\u0000 <mo>/</mo>\u0000 <msup>\u0000 <mi>H</mi>\u0000 <mn>2</mn>\u0000 </msup></math>. Students and practitioners can improve or gain new insights into their understanding of BMI's historical origins and quantitative underpinning from the provided overview, facilitating informed use of BMI and related indices in research and clinical settings.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13842","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142398865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review on drug repurposing applicable to obesity 回顾适用于肥胖症的药物再利用。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-09 DOI: 10.1111/obr.13848
Feng Chen, Kai Jing, Zhen Zhang, Xia Liu
{"title":"A review on drug repurposing applicable to obesity","authors":"Feng Chen,&nbsp;Kai Jing,&nbsp;Zhen Zhang,&nbsp;Xia Liu","doi":"10.1111/obr.13848","DOIUrl":"10.1111/obr.13848","url":null,"abstract":"<div>\u0000 \u0000 <p>Obesity is a major public health concern and burden on individuals and healthcare systems. Due to the challenges and limitations of lifestyle adjustments, it is advisable to consider pharmacological treatment for people affected by obesity. However, the side effects and limited efficacy of available drugs make the obesity drug market far from sufficient. Drug repurposing involves identifying new applications for existing drugs and offers some advantages over traditional drug development approaches including lower costs and shorter development timelines. This review aims to provide an overview of drug repurposing for anti-obesity medications, including the rationale for repurposing, the challenges and approaches, and the potential drugs that are being investigated for repurposing. Through advanced computational techniques, researchers can unlock the potential of repurposed drugs to tackle the global obesity epidemic. Further research, clinical trials, and collaborative efforts are essential to fully explore and leverage the potential of drug repurposing in the fight against obesity.</p>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142386794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to “Role of telemedicine in the management of obesity: State of the art review” 更正 "远程医疗在肥胖症管理中的作用:最新进展回顾"。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-09 DOI: 10.1111/obr.13846
{"title":"Correction to “Role of telemedicine in the management of obesity: State of the art review”","authors":"","doi":"10.1111/obr.13846","DOIUrl":"10.1111/obr.13846","url":null,"abstract":"<p>\u0000 <span>Shariq, K.</span>, <span>Siddiqi, TJ</span>, <span>Spall, H</span>, et al. <span>Role of telemedicine in the management of obesity: state-of-the-art review</span>. <i>Obes Rev</i>. <span>2024</span>; <span>25</span>(<span>6</span>)e13734. doi:10.1111/obr.13734</p><p>The corresponding author of this article should be Kainat Shariq. Details of the new corresponding author are mentioned below.</p><p>Kainat Shariq, MBBS, Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan. Email: <span>[email protected]</span></p><p>We apologize for this error.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13846","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142386796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of interventions aimed at reducing explicit and implicit weight bias in healthcare students: A systematic review and meta-analysis 旨在减少医学生显性和隐性体重偏差的干预措施的效果:系统回顾和荟萃分析。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-08 DOI: 10.1111/obr.13847
Ravisha S. Jayawickrama, Briony Hill, Moira O'Connor, Stuart W. Flint, Erik Hemmingsson, Lucy R. Ellis, Yaxing Du, Blake J. Lawrence
{"title":"Efficacy of interventions aimed at reducing explicit and implicit weight bias in healthcare students: A systematic review and meta-analysis","authors":"Ravisha S. Jayawickrama,&nbsp;Briony Hill,&nbsp;Moira O'Connor,&nbsp;Stuart W. Flint,&nbsp;Erik Hemmingsson,&nbsp;Lucy R. Ellis,&nbsp;Yaxing Du,&nbsp;Blake J. Lawrence","doi":"10.1111/obr.13847","DOIUrl":"10.1111/obr.13847","url":null,"abstract":"<p>We conducted a systematic review and meta-analysis to determine the efficacy of interventions aimed at reducing weight bias in healthcare students, and to explore factors that may impact intervention success. A systematic review and random-effects meta-analyses were conducted by including studies that examined the efficacy of weight bias reduction interventions for healthcare students. Of the 3463 journal articles and dissertations screened, 67 studies (within 64 records) met inclusion criteria, with 35 studies included in the meta-analyses (explicit = 35, implicit [and explicit] = 10) and 32 studies included in the narrative synthesis (explicit = 34, implicit [and explicit] = 3). Weight bias interventions had a small but positive impact, <i>g</i> = −0.31 (95% CI = −0.43 to −0.19, <i>p</i> &lt; 0.001), in reducing students' <i>explicit</i> weight bias but there was no intervention effect on <i>implicit</i> weight bias, <i>g</i> = −0.12 (95% CI = −0.26 to 0.02, <i>p</i> = 0.105). There was considerable heterogeneity in the pooled effect for explicit bias (<i>I</i><sup><i>2</i></sup> = 74.28, <i>Q</i> = 132.21, <i>df</i> = 34, <i>p</i> &lt; 0.001). All subgroup comparisons were not significant (<i>p</i> &gt; 0.05) and were unable to explain the observed heterogeneity. Narrative synthesis supported meta-analytic findings. The small but significant reduction of explicit weight bias encourages the continued testing of interventions, irrespective of variation in individual intervention components. Contrarily, reductions in implicit weight bias may only be possible from a large societal shift in negative beliefs and attitudes held towards people living in larger bodies.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142386798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bariatric surgeries and cardiac structure and function: Systematic review and network meta-analysis 减肥手术与心脏结构和功能:系统回顾和网络荟萃分析。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-08 DOI: 10.1111/obr.13843
Xiao-Qian Zhang, Ke-Ning Chen, Zu-Xuan Zhang, Nian-Rong Zhang, Fang-Jie-Yi Zheng, Biao Zhou, Hua Meng, Zhi-Xin Zhang, Wen-Quan Niu
{"title":"Bariatric surgeries and cardiac structure and function: Systematic review and network meta-analysis","authors":"Xiao-Qian Zhang,&nbsp;Ke-Ning Chen,&nbsp;Zu-Xuan Zhang,&nbsp;Nian-Rong Zhang,&nbsp;Fang-Jie-Yi Zheng,&nbsp;Biao Zhou,&nbsp;Hua Meng,&nbsp;Zhi-Xin Zhang,&nbsp;Wen-Quan Niu","doi":"10.1111/obr.13843","DOIUrl":"10.1111/obr.13843","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Obesity, a global health problem, is causally implicated in the development of cardiovascular disease. Bariatric surgeries are effective treatment options for obesity; however, the effectiveness of different bariatric surgeries on cardiac structure and function is not fully understood. We undertook a systematic review and network meta-analysis to comprehensively assess this effectiveness.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Data source</h3>\u0000 \u0000 <p>PubMed, Web of Science, and EMBASE were searched from their inception until November 11, 2023. Studies that compared bariatric surgeries vis-à-vis non-surgical treatment, placebo, and other bariatric surgeries, as well as reported changes in left ventricular mass or its index (LVM or LVMI) or left ventricular ejection fraction (LVEF), were summarized.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Total 19 studies (17 cohort studies and 2 randomized controlled trials) and 2012 adults were meta-analyzed. Patients receiving gastric bypass had appreciably lowered LVM (weighted mean difference [WMD]: −43.86 g, 95% confidence interval [CI] −61.09 to −26.63, <i>p</i> &lt; 0.01) and LVMI (standardized mean difference: −0.67, 95% CI −1.03 to −0.32, <i>p</i> &lt; 0.01) compared with other bariatric surgeries. No significant improvement in LVEF was noted across all surgeries. The drop in body mass index was most pronounced for biliopancreatic diversion with duodenal switch (WMD −16.33 kg/m<sup>2</sup>, 95% CI −21.60 to −11.05, <i>p</i> &lt; 0.01).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our findings of this network meta-analysis indicated that gastric bypass proved best for the improvement in cardiac structure, and there was no obvious improvement in cardiac function for all bariatric surgeries. Further studies are required to better understand the differing effectiveness of bariatric surgeries on cardiac structure and function and the underlying molecular mechanisms.</p>\u0000 </section>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142386795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary calcium intake in relation to metabolic syndrome in adults: A systematic review and dose–response meta-analysis of epidemiological studies with GRADE assessment 膳食钙摄入量与成人代谢综合征的关系:通过 GRADE 评估对流行病学研究进行系统回顾和剂量反应荟萃分析。
IF 8 2区 医学
Obesity Reviews Pub Date : 2024-10-08 DOI: 10.1111/obr.13850
Roxana Nematbakhsh, Parisa Rouhani, Parvane Saneei
{"title":"Dietary calcium intake in relation to metabolic syndrome in adults: A systematic review and dose–response meta-analysis of epidemiological studies with GRADE assessment","authors":"Roxana Nematbakhsh,&nbsp;Parisa Rouhani,&nbsp;Parvane Saneei","doi":"10.1111/obr.13850","DOIUrl":"10.1111/obr.13850","url":null,"abstract":"<div>\u0000 \u0000 <p>Numerous studies have examined the relationship of calcium intake and metabolic syndrome (MetS) in adults in previous decades; but the results were inconsistent across different societies. This systematic review and dose–response meta-analysis assessed the relation between calcium consumption and MetS in adults. We did a systematic search of all articles published up to July 2023 in Scopus, PubMed/Medline, ISI Web of Science electronic databases, and Google Scholar. Observational studies investigated the association between dietary calcium (Ca) intake and MetS in adults were eligible to be included. For computing the estimates, a random effects model was applied. Combining 24 effect size from 17 investigations (15 cross-sectional and two cohort studies) with 74,720 participants and 18,200 cases showed that highest versus lowest level of dietary Ca intake was related to 23% significant decreased odds of MetS (OR = 0.77; 95% CI: 0.66, 0.89). Linear dose–response analysis of estimates from 12 investigations showed that each 100 mg/day increment in dietary Ca intake was associated with 3% marginally significant decreased odds in MetS (OR = 0.97; 95%CI: 0.93, 1.01). In nonlinear dose–response analysis of 12 studies with 67,896 participants, a significant association between dietary calcium intake and MetS was found (P<sub>nonlinearity</sub> &lt;0.001); such that 500 mg/day dietary calcium intake was related to maximum decrease in odds of MetS. According to this meta-analysis, the likelihood of MetS was significantly lower in adults with higher level of dietary calcium intake. Further large-scale prospective cohort investigations are needed to obtain stronger and more accurate results.</p>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 2","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142386797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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