Obesity Reviews最新文献

An Insight Into Adipose Tissue Thermogenesis Regulated by N⁶-Methyladenosine: Mechanisms and Therapeutic Implications. n6 -甲基腺苷调控的脂肪组织产热机制及其治疗意义

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-10-04 DOI: 10.1111/obr.70029

Yuan-Hai Sun, Ya-Qian Feng, Sun-Ying Cheng, Ling-Huan Li, Han-Bing Li

引用次数: 0

A Systematic Review and Meta-Analytic Assessment of Unpredictability and Disordered Eating. 不可预测性与饮食失调的系统回顾与元分析评估。

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-10-01 DOI: 10.1111/obr.70022

Tomás Cabeza de Baca, Hannah T Fry, Andrés M Treviño-Alvarez, Gisela Butera, Brooke Betsuie, Marci E Gluck

{"title":"A Systematic Review and Meta-Analytic Assessment of Unpredictability and Disordered Eating.","authors":"Tomás Cabeza de Baca, Hannah T Fry, Andrés M Treviño-Alvarez, Gisela Butera, Brooke Betsuie, Marci E Gluck","doi":"10.1111/obr.70022","DOIUrl":"https://doi.org/10.1111/obr.70022","url":null,"abstract":"Perceived unpredictability, whether it relates to experiences, food availability, or belief systems, may predict disordered eating behaviors and affect weight gain and future health. Past studies investigating the associations of unpredictability and disordered eating, however, have shown inconsistent findings. The current review aimed to examine the associations between measures of unpredictability and subjective and objective measures of disordered eating behaviors in adults and children. A systematic review was conducted in July 2023, searching six databases: PubMed/MEDLINE, Embase, Cochrane Library, Web of Science: Core Collection, PsycInfo, and ProQuest Dissertations and Theses, where 20 relevant research articles were identified. Eighty-three correlation coefficients were extracted from 15 articles (n = 9983). Results from a four-level random effects meta-analysis found a small, but significant association between unpredictability and disordered eating (r = 0.12, 95% CI = 0.08, 0.17, p < 0.0001), with a significant (Q [82] = 461.55, p < 0.0001) and large degree of heterogeneity (I2 = 86.72%). Country of origin, mode of measurement for disordered eating, chronicity of unpredictability, and study percentage of women were identified as significant moderators. These findings highlight the need for assessment of unpredictability with more rigorous and improved measures of disordered eating to understand the impact on health outcomes.","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e70022"},"PeriodicalIF":7.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heterogeneity of Obesity and Its Predictive Factors: A Narrative Review of Recent Human and Rodent Studies. 肥胖的异质性及其预测因素：最近人类和啮齿动物研究的述评。

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-10-01 DOI: 10.1111/obr.70024

Pengfei Liu, Mengdi Zhang, Ang Li, Tongzhe Lv, Jiale Lu, Wenbo Chen, Kaili Yin, Guo Zhang

{"title":"Heterogeneity of Obesity and Its Predictive Factors: A Narrative Review of Recent Human and Rodent Studies.","authors":"Pengfei Liu, Mengdi Zhang, Ang Li, Tongzhe Lv, Jiale Lu, Wenbo Chen, Kaili Yin, Guo Zhang","doi":"10.1111/obr.70024","DOIUrl":"https://doi.org/10.1111/obr.70024","url":null,"abstract":"As \"obesogenic environments\" grow increasingly prevalent, obesity has become a pressing global health challenge. It has been somewhat overlooked that individual responses to this obesogenic condition tend to be varied, and the mechanism behind this variability remains poorly understood. In the current study, we seek to summarize recent studies of human subjects and rodents that aim to identify the predictive factors of the heterogeneity of obesity. These factors include baseline fat mass (FM), fat-free mass (FFM), muscle oxidative capacity, VO2max, androgen level, plasma leptin level, physical activity (PA), energy intake (EI), and genes such as SFRP5, MEST, and BMP3. Influenced by both genetic and environmental conditions, these factors provide a comprehensive framework for understanding the causes why individuals, even under the same obesogenic environment, exhibit differing weight gain responses. Our review synthesizes the existing literature to highlight these predictive factors, such as FM and FFM, as strong potential indicators of future weight gain and obesity risk. Integrating these factors into a unified framework not only enhances our understanding of obesity susceptibility but also provides a foundation for developing personalized obesity prevention and treatment strategies.","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e70024"},"PeriodicalIF":7.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex Disparities in Obesity: A Comprehensive Review of Hormonal and Genetic Influences on Obesity-Related Phenotypes. 肥胖的性别差异：激素和遗传对肥胖相关表型影响的综合综述。

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-09-30 DOI: 10.1111/obr.70026

Yu-Gyeong Lee, Yoo-Ree Kang, Yoomee Chang, Jongmin Kim, Mi-Kyung Sung

{"title":"Sex Disparities in Obesity: A Comprehensive Review of Hormonal and Genetic Influences on Obesity-Related Phenotypes.","authors":"Yu-Gyeong Lee, Yoo-Ree Kang, Yoomee Chang, Jongmin Kim, Mi-Kyung Sung","doi":"10.1111/obr.70026","DOIUrl":"https://doi.org/10.1111/obr.70026","url":null,"abstract":"The Worldwide Incidence of Obesity, which tripled in 2016 from 1975, is a leading risk factor for chronic diseases. The presence of sex-dependent disparities in obesity has spurred increased interest in understanding the diverse environmental and genetic factors influencing this condition. Typically, men tend to have more visceral adipose tissue (VAT), while women generally have higher amounts of subcutaneous adipose tissue (SAT). These differences have been largely attributed to the effects of sex hormones, particularly estrogen. However, large-scale genome-wide association studies (GWAS) have identified genetic factors associated with sex-dependent disparities in obesity-related traits, which revealed that the role of estrogen may have been overemphasized. This review aims to summarize sex-specific differences in adipose tissue distribution and adipose tissue type such as white adipose tissue (WAT) and brown adipose tissue (BAT). Additionally, the mechanisms underlying the development of sex-specific characteristics are explained, with a focus on estrogen and obesity-associated genes. Specifically, we propose a list of GWAS-derived genes that may be responsible for the observed sex differences in obesity, which could significantly contribute to the existing literature.","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e70026"},"PeriodicalIF":7.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying Social Media-Based Interactions That Help Adults to Adhere to Weight Loss Goals: A Systematic Review. 识别基于社交媒体的互动，帮助成年人坚持减肥目标：系统回顾。

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-09-30 DOI: 10.1111/obr.70030

Constanze Betz, Mirna Al Masri, Laura M König, Tina Bartelmeß

{"title":"Identifying Social Media-Based Interactions That Help Adults to Adhere to Weight Loss Goals: A Systematic Review.","authors":"Constanze Betz, Mirna Al Masri, Laura M König, Tina Bartelmeß","doi":"10.1111/obr.70030","DOIUrl":"https://doi.org/10.1111/obr.70030","url":null,"abstract":"Background: Social media may support weight loss through online interaction and support, but its impact on interactions, social support, psychological factors, and weight loss outcomes across socioeconomic groups is unclear. This review aimed to (1) identify social support mechanisms aiding weight loss on social media, (2) pinpoint effective platforms and functions, and (3) assess intervention effectiveness across diverse demographics.Methods: A comprehensive search of PubMed, PsycINFO, and Web of Science was conducted through mid-2023. Studies included targeted adults without psychiatric disorders and linked social media use to outcomes like weight, diet, physical activity, self-management, or social support. Studies not meeting these criteria were excluded.Results: From 61 studies, informational support was most common (83%), followed by esteem (52%), network (47%), and emotional support (44%). Tangible support was rare due to the need for physical proximity. Informational and esteem support showed positive effects, but challenges like social comparison and negative group dynamics were noted. Facebook was the most studied platform, with higher engagement linked to better outcomes. Factors such as network embeddedness, tailored support, and platform familiarity influenced effectiveness. Only 18 studies addressed social inequality, showing younger individuals and women benefit more from these interventions.Conclusions: Social media facilitates weight loss through diverse support mechanisms, but challenges like varied platform preferences and social inequality require attention. Tailored interventions and strategies to promote engagement and mitigate negative dynamics are critical for maximizing outcomes.","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e70030"},"PeriodicalIF":7.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations Between Weight Discrimination and Health Outcomes by Racial and Ethnic Groups: A Scoping Review. 种族和民族体重歧视与健康结果之间的关系：一项范围综述

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-09-22 DOI: 10.1111/obr.70016

Cherlie Magny-Normilus, Julie Adams Sanders, Patricia Underwood, Rose D LaPlante

{"title":"Associations Between Weight Discrimination and Health Outcomes by Racial and Ethnic Groups: A Scoping Review.","authors":"Cherlie Magny-Normilus, Julie Adams Sanders, Patricia Underwood, Rose D LaPlante","doi":"10.1111/obr.70016","DOIUrl":"https://doi.org/10.1111/obr.70016","url":null,"abstract":"Weight discrimination refers to bias against individuals whose body weight and shape do not align with predominant social norms. Weight discrimination is prevalent and negatively impacts health outcomes. The prevalence and impact of weight discrimination vary by race; however, there is a dearth of research describing the potential health effects across racial and ethnic groups. This scoping review aimed to assess the literature for associations between weight discrimination and health outcomes, with a focus on racial and ethnic differences. A literature search was conducted across five databases for original studies that examined health outcomes associated with weight discrimination and delineated results by race. After quality assessment, thematic analysis was performed to generate themes, and consensus was reached. Twenty articles met the selected inclusion criteria, revealing racial differences in several health outcomes and disease management linked to weight-based discrimination. Social determinants of health and cultural beliefs about body size emerged as potential modifiers of these disparities. Although most studies investigated unique populations and variables, complicating comparisons, the review highlighted racial variances in the prevalence of weight discrimination. Additionally, 25 physical and mental health outcomes were associated with weight discrimination, with body mass index (BMI) being the most common. Future research should further explore the intersection of weight discrimination and race and ethnicity, identifying contributing factors and incorporating personal narratives. Clinicians must consider the influence of culture and social determinants of health to provide equitable care across body size spectrums.","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e70016"},"PeriodicalIF":7.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Obesity a Risk Factor for Periodontitis? A Systematic Review and Meta-Analysis. 肥胖是牙周炎的危险因素吗？系统回顾和荟萃分析。

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-09-16 DOI: 10.1111/obr.70020

Fariba Esperouz, Domenico Ciavarella, Claudio Di Gioia, Gaetano Serviddio, Mauro Lorusso, Lucio Lo Russo

{"title":"Is Obesity a Risk Factor for Periodontitis? A Systematic Review and Meta-Analysis.","authors":"Fariba Esperouz, Domenico Ciavarella, Claudio Di Gioia, Gaetano Serviddio, Mauro Lorusso, Lucio Lo Russo","doi":"10.1111/obr.70020","DOIUrl":"https://doi.org/10.1111/obr.70020","url":null,"abstract":"Objectives: This study aims at reviewing available evidence on the relationship between obesity and periodontitis, focusing on whether obesity is a risk factor for the development and progression of periodontal disease.Materials and methods: This systematic review and meta-analysis were reported in accordance with the PRISMA guidelines. Searches were performed in databases such as PUBMED, SCOPUS, and Web of Science for studies investigating the correlation between obesity (BMI ≥ 30 kg/m2) and periodontitis in adult patients. Heterogeneity was assessed using the I2 statistic, and a meta-analysis was performed to calculate pooled odds ratios with 95% confidence intervals.Results: The analysis included 19 studies with a total of 41,107 patients. The meta-analysis showed a significant association between obesity and an increased risk of periodontitis (OR = 1.31 95% CI: 1.22-1.41) confirming that obesity is a risk factor for periodontal disease.Conclusion: The results suggest that obesity is significantly associated with an increased risk of periodontitis. Given this correlation, further research is needed to better understand the implications of this association on clinical outcomes.","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e70020"},"PeriodicalIF":7.4,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Holistic Approach to Describe, Monitor, Evaluate, and Learn From Government Engagement With Private-Sector Actors to Promote Healthy Food Environments.

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-09-16 DOI: 10.1111/obr.70019

Vivica I Kraak

引用次数: 0

Correction to "The Effectiveness of Interventions on Changing Caregivers' Feeding Practices With Preschool Children: A Systematic Review and Meta-Analysis". 对“改变照顾者喂养学龄前儿童的干预措施的有效性：一项系统回顾和荟萃分析”的更正。

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-09-11 DOI: 10.1111/obr.70018

引用次数: 0

Examining the Role of Sleep in Body Weight Regulation and Implications for Obesity Treatment: A Narrative Review. 研究睡眠在体重调节中的作用及其对肥胖治疗的影响：一篇叙述性综述。

IF 7.4 2区医学

Obesity Reviews Pub Date : 2025-09-08 DOI: 10.1111/obr.70017

Rebecca Rosenberg, Matthew J Breit, Kevin C Clark, Josiane L Broussard, Victoria A Catenacci, Christopher M Depner, Stacey L Simon, Kenneth P Wright, Faris M Zuraikat, Seth A Creasy

{"title":"Examining the Role of Sleep in Body Weight Regulation and Implications for Obesity Treatment: A Narrative Review.","authors":"Rebecca Rosenberg, Matthew J Breit, Kevin C Clark, Josiane L Broussard, Victoria A Catenacci, Christopher M Depner, Stacey L Simon, Kenneth P Wright, Faris M Zuraikat, Seth A Creasy","doi":"10.1111/obr.70017","DOIUrl":"https://doi.org/10.1111/obr.70017","url":null,"abstract":"Despite significant public health efforts to counter the obesity epidemic, approximately 50% of US adults will have obesity by 2030. The cornerstone of obesity treatment is a behavioral intervention promoting negative energy balance via a reduced-calorie diet and increased physical activity. Behavioral treatment also requires additional support to promote adherence to these recommended lifestyle changes. More recently, sleep has been recognized as an important component of body weight regulation due to its effects on physiological and behavioral determinants of energy balance. Therefore, sleep may represent a modifiable behavior to target during the behavioral treatment of obesity. This review summarizes existing clinical evidence on the influence of sleep on energy balance and body weight regulation in adults. The results of controlled laboratory studies as well as pragmatic clinical trials are reviewed. In addition, we identify existing gaps and future areas of research that are necessary to understand the role of sleep in behavioral treatments for obesity.","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e70017"},"PeriodicalIF":7.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0