Saudi Medical Journal最新文献_第2页

Patient Safety Culture Among Healthcare Professionals in Jeddah First Health Cluster: A Multi-Professional Cross-Sectional Study. 吉达第一卫生集群医疗专业人员的患者安全文化：一项多专业横断面研究。

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-09-01 Epub Date: 2026-08-06 DOI: 10.15537/1658-3175.8841

Saad S Alyazidi, Salah S Alshagrawi

{"title":"Patient Safety Culture Among Healthcare Professionals in Jeddah First Health Cluster: A Multi-Professional Cross-Sectional Study.","authors":"Saad S Alyazidi, Salah S Alshagrawi","doi":"10.15537/1658-3175.8841","DOIUrl":"10.15537/1658-3175.8841","url":null,"abstract":"Objective: Patient safety culture (PSC) is essential to improve healthcare quality and reduce preventable harm. Despite ongoing healthcare transformation in Saudi Arabia, there is limited evidence on healthcare professionals' (HCPs) perceptions of PSC in newly established health clusters.Methods: We conducted a cross-sectional study among HCPs in 6 government hospitals within the Jeddah First Health Cluster, Saudi Arabia. Data were gathered utilizing the Hospital Survey on PSC (HSOPSC). Descriptive measurement sand multiple linear regression analyses were used to evaluate perceptions of PSC and associated factors.Results: A total of 256 HCPs participated in the study. Overall, PSC was perceived as moderately positive (mean = 3.40, SD = 0.41). Teamwork within units of reported events received the highest scores, indicating positive collaboration among staff. Staffing, less punitive response to error, and handoffs and transitions scores were low, highlighting concerns related to workforce adequacy, communication during care transitions, and fear of blame when reporting incidents. Regression analysis showed that demographic and professional characteristics were not significant predictors of overall PSC scores.Conclusion: The HCPs generally reported positive experiences of PSC; however, challenges related to staffing, communication, and non-punitive error reporting remain. Strengthening organizational communication and promoting a just culture may improve patient safety practices across healthcare facilities.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 9","pages":"1506-1515"},"PeriodicalIF":2.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13471427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148761148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Establishment of a Specialized Pectus Clinic: Referral Patterns, Diagnostic Characteristics, and Early Management Experience at a University Hospital. 建立专门的胸肌诊所：转诊模式、诊断特点和大学医院的早期管理经验。

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-09-01 Epub Date: 2026-08-06 DOI: 10.15537/1658-3175.8844

Zeead M AlGhamdi

{"title":"Establishment of a Specialized Pectus Clinic: Referral Patterns, Diagnostic Characteristics, and Early Management Experience at a University Hospital.","authors":"Zeead M AlGhamdi","doi":"10.15537/1658-3175.8844","DOIUrl":"10.15537/1658-3175.8844","url":null,"abstract":"Objectives: To describe the establishment and early impact of a dedicated pectus clinic at a university hospital, focusing on patient characteristics, referral pathways, clinical presentation, and initial management strategies.Methods: A retrospective observational study was conducted at a university hospital between January 2020 and April 2025, with 153 patients included in the final analysis. Data collected included demographic characteristics, referral sources, clinical presentation, deformity type, and treatment options. Descriptive statistical analysis was performed.Results: The mean patient age was 18.3 (range 1-44) years, with males accounting for 83.9% of cases. Pectus carinatum was the most common diagnosis (48.1%), followed by pectus excavatum (42.3%). Patient-initiated referrals, including those influenced by digital and social media platforms, represented 63.2% of referrals. Psychosocial concerns were the main presenting complaint in 60.6% of patients, whereas isolated functional symptoms were reported in 9%. Annual visits increased progressively throughout the study period. Non-operative treatment was commonly used for pectus carinatum, while surgical management was more frequent for pectus excavatum.Conclusions: A dedicated pectus clinic improved access to specialized care and supported structured management. The high proportion of patient-initiated referrals highlights the growing role of non-traditional referral pathways. The specialized clinic improved awareness, standardized the care, and addressed unmet needs in patients with pectus deformities.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 9","pages":"1542-1548"},"PeriodicalIF":2.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13471426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of F-18 FDG PET/CT in the Evaluation of Solitary Pulmonary Nodules. F-18 FDG PET/CT在孤立性肺结节诊断中的作用

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-09-01 Epub Date: 2026-08-06 DOI: 10.15537/1658-3175.8838

Erdal Cetinkaya, Fatih Guzel, Sadiye Altun Tuzcu, Ilbey Erkin Cetin, Ibrahim Ibiloglu, Esref Argin, Feray Altun Cetin, Bekir Tasdemir

{"title":"The Role of F-18 FDG PET/CT in the Evaluation of Solitary Pulmonary Nodules.","authors":"Erdal Cetinkaya, Fatih Guzel, Sadiye Altun Tuzcu, Ilbey Erkin Cetin, Ibrahim Ibiloglu, Esref Argin, Feray Altun Cetin, Bekir Tasdemir","doi":"10.15537/1658-3175.8838","DOIUrl":"10.15537/1658-3175.8838","url":null,"abstract":"Objective: Fluorine-18 fluorodeoxyglucose positronemissiontomography/computedtomography (F-18 FDG PET/CT) is commonly used in the evaluation of solitary pulmonary nodules (SPNs). This study aimed to investigate the predictive value of maximum standardized uptake value (SUVmax) and its ratios to liver and mediastinal blood pool SUVmax values for malignancy in SPNs, using histopathological findings as the reference standard.Methods: The study included 130 patients who underwent F-18 FDG PET/CT and had either histopathological confirmation or at least two years of radiological follow-up. Demographic data (age and sex), nodule size, location, contour characteristics, nodule SUVmax, nodule-to-liver SUVmax ratio (NLR), and nodule-to-mediastinal blood pool SUVmax ratio (NBR) were recorded. Nodules were classified as benign or malignant based on histopathological results.Results: Among the 83 patients with histopathological diagnosis, 54% (n = 44) had malignant lesions and 46% (n = 39) had benign lesions. The mean size of malignant nodules was approximately 20 mm. Receiver operating characteristic (ROC) analysis demonstrated that an SUVmax cutoff value of 4.02 provided the highest diagnostic accuracy for predicting malignancy. Both NLR and NBR showed significant diagnostic value in malignancy prediction. These parameters demonstrated high sensitivity (84-91%) and negative predictive value (76-84%), indicating their usefulness in excluding benign nodules.Conclusion: The F-18 FDG PET/CT is a valuable imaging modality in the evaluation of solitary pulmonary nodules. In addition to SUVmax, the use of NLR and NBR may improve diagnostic accuracy and contribute to clinical decision-making.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 9","pages":"1479-1486"},"PeriodicalIF":2.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13471414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148765266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bibliometric Analysis of the Top 100 Most Cited Publications from Saudi Arabia Reveals the Predominance of Medical Fields. 沙特阿拉伯前100名被引用最多的出版物的文献计量分析揭示了医学领域的优势。

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-09-01 Epub Date: 2026-08-06 DOI: 10.15537/1658-3175.8845

Mahmoud Kandeel, Abdulla Al-Taher

{"title":"Bibliometric Analysis of the Top 100 Most Cited Publications from Saudi Arabia Reveals the Predominance of Medical Fields.","authors":"Mahmoud Kandeel, Abdulla Al-Taher","doi":"10.15537/1658-3175.8845","DOIUrl":"10.15537/1658-3175.8845","url":null,"abstract":"Objectives: To explore the citation impact, journals, international collaborations, trends of research topics and gain more visibility for the Saudi contribution to the global scientific landscape.Methods: This bibliometric study analyzes the top 100 cited publications affiliated with Saudi Arabia in Scopus, from inception to January 2026. The extracted bibliometric indicators include total citation metrics, sources, collaboration maps, and co-occurrence networks of keywords and collaborations.Results: The results indicate a strong predominance for medicine and health sciences as the subjects of the most prolific and significant number of citations. A substantial proportion of the most cited papers originates from major global health projects, in particular the Global Burden of Disease (GBD) consortium, which focuses on mortality, morbidity, and epidemiological metrics. Clinical and public health fields are highly represented, including obesity and cardiovascular risk, disease burden, and population health metrics. The most frequent journals include the leading medical journals in the field, namely The Lancet, Nature, Science and the New England Journal of Medicine. Keyword analysis confirms the dominance of medical themes; the most prominent keywords included epidemiology, risk factors, and global health indicators. Within the biomedical predominance, bioinformatics tools such as MEGA software contribute to the citation impact.Conclusions: Saudi Arabia's citation impact is predominantly driven by international consortia participation and bioinformatics tool development, highlighting the opportunities for strengthening independent and nationally led research programs of global significance.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 9","pages":"1558-1566"},"PeriodicalIF":2.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13471456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148761727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient Experiences and Safety Concerns Regarding GLP-1 Receptor Agonists for Obesity: A Cross-Sectional Survey in Jeddah, Saudi Arabia. GLP-1受体激动剂治疗肥胖症的患者经历和安全问题：沙特阿拉伯吉达的一项横断面调查。

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-09-01 Epub Date: 2026-08-06 DOI: 10.15537/1658-3175.8842

Mansour A Tobaiqy, Sulafa T Alqutub, Mohammed A Alzahrani, Renad H Alazwari, Faisal A Asiri

{"title":"Patient Experiences and Safety Concerns Regarding GLP-1 Receptor Agonists for Obesity: A Cross-Sectional Survey in Jeddah, Saudi Arabia.","authors":"Mansour A Tobaiqy, Sulafa T Alqutub, Mohammed A Alzahrani, Renad H Alazwari, Faisal A Asiri","doi":"10.15537/1658-3175.8842","DOIUrl":"10.15537/1658-3175.8842","url":null,"abstract":"Objective: To evaluate the perceptions, experiences, and safety concerns of patients regarding the glucagon-like peptide-1 (GLP-1) receptor agonists. Obesity is a significant public health issue. The newer anti-obesity medications: GLP-1 receptor agonists, with an increase in therapeutic options. However, little is known about the perceived benefits, safety, cost, and accessibility.Methods: Cross-sectional survey included adults who previously used at least 1 anti-obesity medication and conducted in 3 general hospitals in Jeddah, Kingdom of Saudi Arabia (KSA) during June 2025 to February 2026. The questionnaire was created after reviewing the current evidence and validated the contents. It included questions on demographic and clinical information, medication use patterns, perceptions, and safety experiences. Data were analyzed using descriptive statistics.Results: A total of 365 participants (median age: 41 years; 55.3% female) included, with a median body mass index (BMI) of 29.59 kg/m2 and 48.6% were obese. Current medication use was 63.3%, associated with diabetes, hypertension, hypercholesterolemia, family obesity history, and higher BMI. Duration of use was statistically significant (p = 0.001), with tirzepatide used for longer durations and semaglutide for shorter durations. Perceived safety was significantly associated with the duration of use (p = 0.001). Despite adverse effects reporting, many questioned effectiveness, information adequacy and safety.Conclusion: Substantial gaps in perceived effectiveness, safety confidence, affordability, and therapy continuity of GLP-1 receptor. This highlights need for structured education, improved access, and system interventions to improve anti-obesity pharmacotherapy adherence.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 9","pages":"1516-1523"},"PeriodicalIF":2.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13471477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148765250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Al Kuwait Hospital Dubai, Emirates Health Services 1st Research Week 2025: Research Abstracts of Clinical and Scientific Advances. 迪拜科威特医院，阿联酋卫生服务2025年第一个研究周：临床和科学进展研究摘要。

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-08-01 Epub Date: 2026-07-07 DOI: 10.15537/1658-3175.8831

Suad Hannawi, Linda Saf Eldin, Alaa Abuquta, Yusra Abdulrahman, Maryam Yaslam, Sabaa Saleh Al-Hemyari, Maimouneh Qazi, Noor Majed Al Mheiri, Ahmed Alamadi, Alia Aljasmi, Sondos Al Salmi, Maria Al-Salmi, Moza Aljamri, Ahmed Ibrahim Abdulrahman, Sharifa Alamadi, Haifa Hannawi

引用次数: 0

Prevalence and Clinical Correlates of Intraspinal and Vertebral Anomalies in Congenital, Adolescent Idiopathic, and New-Onset Scoliosis: A Comparative Study in Saudi Arabia. 先天性、青少年特发性和新发脊柱侧凸的患病率和脊柱内异常的临床相关性：沙特阿拉伯的一项比较研究。

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-08-01 Epub Date: 2026-07-07 DOI: 10.15537/1658-3175.8823

Faisal M Alkhunein, Mishari N Alanezi, Nwaf A Alshahir, Abdulkarim S Alsulimi, Abdulrahman H Salman, Habib Ullah Chaudhary, Abdulmajeed A Alzakri

{"title":"Prevalence and Clinical Correlates of Intraspinal and Vertebral Anomalies in Congenital, Adolescent Idiopathic, and New-Onset Scoliosis: A Comparative Study in Saudi Arabia.","authors":"Faisal M Alkhunein, Mishari N Alanezi, Nwaf A Alshahir, Abdulkarim S Alsulimi, Abdulrahman H Salman, Habib Ullah Chaudhary, Abdulmajeed A Alzakri","doi":"10.15537/1658-3175.8823","DOIUrl":"10.15537/1658-3175.8823","url":null,"abstract":"Objective: To explore the prevalence of and clinical associations between intraspinal and vertebral abnormalities in patients with congenital scoliosis (CS), adolescent idiopathic scoliosis (AIS), and early-onset scoliosis in Saudi Arabia.Methods: This retrospective cohort investigation included patients aged 18 years or younger diagnosed with CS, AIS, or new-onset idiopathic scoliosis who underwent full-spine magnetic resonance imaging between 2015 and 2025 at a tertiary center in Riyadh, Saudi Arabia. Clinical and radiological data were collected, and intraspinal and vertebral anomalies were classified. Statistical analyses included Chi-square, Fisher's exact test, and the Wilcoxon rank-sum test, with significance set at p < 0.05.Results: A total of 127 patients fulfilled the inclusion criteria; idiopathic scoliosis accounted for 80.3% and CS for 19.7%. Intraspinal anomalies were identified in 7.9% of patients, with a higher prevalence in CS (24%) than in idiopathic scoliosis (3.9%). Low conus was the most common anomaly (40%). Vertebral defects in CS were mainly failures of formation (76%), most commonly hemivertebrae, predominantly affecting the thoracic spine. Congenital scoliosis was significantly associated with a higher incidence of intraspinal anomalies (p = 0.004).Conclusion: Intraspinal anomalies were substantially more common in CS than in idiopathic forms in this Saudi cohort, underscoring the importance of routine preoperative magnetic resonance imaging to guide risk assessment and surgical planning.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 8","pages":"1316-1321"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13360741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148437779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Healthcare-Associated Infection Causes and Mitigation Strategies: A Systematic Review. 医疗保健相关感染的原因和缓解策略：系统综述。

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-08-01 Epub Date: 2026-07-07 DOI: 10.15537/1658-3175.8817

Mohammad Irfan, Nahed Alquwez

{"title":"Healthcare-Associated Infection Causes and Mitigation Strategies: A Systematic Review.","authors":"Mohammad Irfan, Nahed Alquwez","doi":"10.15537/1658-3175.8817","DOIUrl":"10.15537/1658-3175.8817","url":null,"abstract":"Objective: To describe the landscape of healthcare-associated infections (HAI) and, in particular, to pay attention to the types of infection that are usually seen, the most common infectious agents involved and the effective prevention strategies.Methods: A detailed search was performed using Google and PubMed, and studies that exclusively addressed healthcare associated infections or their mitigation. Studies published since 2000 were included. Data from individual articles were extracted and categorized by study focus, type of infection, causes and contributing factors, and documented mitigation strategies. Editorials, reviews, case studies, meta-analyses, and systematic reviews were excluded.Results: The analysis showed that infections related to healthcare, particularly bloodstream infections, infections that occur in intensive care units, and surgical site infections, significantly burden healthcare systems. Bacterial pathogens, including drug-resistant strains, such as Staphylococcus aureus, were identified as the most prominent etiologic agents, as well as several viral pathogens. The findings also underlined the importance of strong surveillance systems and especially systems that take advantage of digital platforms to effectively monitor the trends of infection and antibiotic resistance.Conclusions: The review highlighted the serious need for effective monitoring systems, especially those that use digital platforms, to monitor trends of infection and antibiotic resistance. The study highlighted the importance of a multifaceted preventive approach that involves prophylactic and therapeutic measures, as well as strict adherence to the sterile technique in healthcare institutions.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 8","pages":"1255-1264"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13360679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148437793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary Fat Intake and Its Influence on the Association Between Liver Fat and Brain Choline Metabolism in Young Saudi Women. 沙特年轻女性膳食脂肪摄入量及其对肝脏脂肪和脑胆碱代谢关系的影响

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-08-01 Epub Date: 2026-07-07 DOI: 10.15537/1658-3175.8822

Halima S Hawesa, Mansour E Shanawani, Haya A Alshegri, Mahasin G Hassan, Amal I Alorainy, Nouf A Alroqaiba, Shanoo G A Sheikh

{"title":"Dietary Fat Intake and Its Influence on the Association Between Liver Fat and Brain Choline Metabolism in Young Saudi Women.","authors":"Halima S Hawesa, Mansour E Shanawani, Haya A Alshegri, Mahasin G Hassan, Amal I Alorainy, Nouf A Alroqaiba, Shanoo G A Sheikh","doi":"10.15537/1658-3175.8822","DOIUrl":"10.15537/1658-3175.8822","url":null,"abstract":"Objective: Fat-rich nutrition may influence the neurochemical consequences of hepatic lipid accumulation. This study examined whether percent energy from fat modifies the association between liver fat and the brain (Cho/Cr) ratio in healthy young women.Methods: A total of 109 healthy Saudi women aged 18-25 years underwent brain magnetic resonance spectroscopy (1H-MRS) to quantify Cho/Cr ratios. Liver fat was estimated using MRI-based proton density fat fraction (PDFF), and lipid intake was assessed using a validated food frequency questionnaire. Multivariable regression models tested the interaction between liver fat and fat-derived energy intake, followed by simple slopes analysis, regression diagnostics, and false discovery rate (FDR) correction.Results: A modest but statistically significant interaction was observed between liver fat and reported fat intake in relation to the brain Cho/Cr ratio (p = 0.037). The association between liver fat and Cho/Cr appeared stronger at higher levels of fat consumption (+1 SD) and weaker at lower intake (-1 SD). Regression diagnostics indicated no multicollinearity or heteroscedasticity, and FDR correction supported the stability of the interaction.Conclusion: Fat intake may modify the relationship between liver fat and brain choline metabolism in young women. These findings suggest that nutritional context could play a role in liver-brain metabolic coupling, although the effect size is modest and should be interpreted with caution.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 8","pages":"1309-1315"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13360573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148437700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Use of Platelet-Rich Plasma for De Quervain's Tenosynovitis: A Systematic Review With Limited Meta-Analysis. 富血小板血浆治疗De Quervain腱鞘炎：一项有限荟萃分析的系统综述。

IF 2.1 4区医学

Saudi Medical Journal Pub Date : 2026-08-01 Epub Date: 2026-07-07 DOI: 10.15537/1658-3175.8818

Abdullah W Abumadian, Mohanad I Binibrahim, Abdurrahman H Sultan, Mohammed A Addas, Hattan Y Bamagaus, Sultan K Alhaddad, Motasem O Bamabad, Bayan A Ghalimah

{"title":"The Use of Platelet-Rich Plasma for De Quervain's Tenosynovitis: A Systematic Review With Limited Meta-Analysis.","authors":"Abdullah W Abumadian, Mohanad I Binibrahim, Abdurrahman H Sultan, Mohammed A Addas, Hattan Y Bamagaus, Sultan K Alhaddad, Motasem O Bamabad, Bayan A Ghalimah","doi":"10.15537/1658-3175.8818","DOIUrl":"10.15537/1658-3175.8818","url":null,"abstract":"Introduction: De Quervain's tenosynovitis (DQT) is a painful wrist condition that impairs daily activities. Corticosteroid (CS) injections are commonly used for symptom relief, but their effects may diminish over time. Platelet-rich plasma (PRP) has emerged as a regenerative alternative that promotes tissue healing rather than merely suppressing inflammation. This systematic review and limited meta-analysis compare the efficacy and safety of PRP versus CS injections in DQT. A limited meta-analysis was chosen due to the high heterogeneity between studies (I2 = 98.7%).Methodology: A comprehensive literature search identified six studies comparing PRP and CS injections. Pain and functional outcomes were assessed using the Visual Analog Scale (VAS), Disabilities of the Arm, Shoulder, and Hand (DASH) score, and Mayo Wrist Score (MWS). Statistical significance was analyzed, with follow-up durations ranging from 2 weeks to one year. The risk of bias was evaluated using Cochrane and ROBINS-I tools.Results: Both PRP and CS significantly reduced pain; however, PRP provided superior long-term relief. The VAS scores improved in all studies, with PRP showing significantly greater reduction at 6 months (p < 0.001). A study also found better QuickDASH-9 scores in PRP-treated patients (p < 0.01). The PRP had fewer complications than CS p=0.026, reinforcing its safety advantage.Conclusion: The PRP and CS effectively reduce pain, but preliminary evidence suggests PRP may offer longer-lasting symptom relief than corticosteroids; however, findings are limited by small sample sizes, study heterogeneity, and low certainty of evidence. Further high-quality trials with standardized PRP protocols are warranted.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"47 8","pages":"1265-1276"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13360672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148437810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0