Saudi Medical Journal最新文献_第10页

Clinical variables influencing the severity of diabetes ketoacidosis. 影响糖尿病酮症酸中毒严重程度的临床变量。

IF 1.6 4区医学

Saudi Medical Journal Pub Date : 2024-05-01 DOI: 10.15537/smj.2024.45.4.20240058

Yara F Alhamdani, Lojain O Almadfaa, Abdulmoein E AlAgha

{"title":"Clinical variables influencing the severity of diabetes ketoacidosis.","authors":"Yara F Alhamdani, Lojain O Almadfaa, Abdulmoein E AlAgha","doi":"10.15537/smj.2024.45.4.20240058","DOIUrl":"10.15537/smj.2024.45.4.20240058","url":null,"abstract":"Objectives: To evaluate clinical indicators in order to examine the intensity of diabetes ketoacidosis (DKA) episodes in children and adolescents diagnosed with type 1 diabetes mellitus (T1DM).Methods: Data from 156 T1DM patients aged 6 months to 14 years, who presented with DKA to the emergency room, were retrospectively reviewed from 2018 to 2022. Data on demographic characteristics, economic status, initial clinical presentation, glycemic control, DKA severity, and laboratory evaluations were also collected.Results: Diabetes ketoacidosis episodes were more prevalent among male patients during the middle childhood age group. Notably, these episodes displayed seasonal patterns. The severity was found to be inversely associated with economic status and positively correlated with early adolescence. Newly diagnosed T1DM patients constituted 52.9%, with a statistically significant connection observed between severe DKA and this subgroup. Furthermore, there was a significant escalation in poor glycemic control with episode severity. Prolonged episode duration also exhibited a statistically significant association with more severity. Gastrointestinal symptoms were commonly reported during the presentation. Moreover, several clinical signs and symptoms, including decreased consciousness, reduced activity, drowsiness, Kussmaul breathing, shortness of breath, vomiting, tachycardia, and severe dehydration, were significantly correlated with the severity of DKA (p<0.05). Hypernatremia was more frequent among children with severe DKA.Conclusion: Diabetes ketoacidosis was observed to occur more frequently among males in middle childhood with seasonal variations. Furthermore, the severity of DKA was associated with lower economic status, early adolescence, and the presence of hypernatremia.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140909203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights and considerations on CFTR variant reporting in a study of cystic fibrosis patients in Saudi Arabia CFTR 1548del G and 1549del G: Navigating the discovery of novel mutations. 沙特阿拉伯囊性纤维化患者研究中 CFTR 变异报告的见解和考虑 CFTR 1548del G 和 1549del G：发现新型突变的导航。

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2024-05-01 DOI: 10.15537/smj.2024.45.5.20240331

Eman A Al Abdulsalam

引用次数: 0

Bilateral renal lymphangiectasia: Literature review of a rare entity. 双侧肾淋巴管扩张症：罕见病例的文献综述。

IF 1.6 4区医学

Saudi Medical Journal Pub Date : 2024-05-01 DOI: 10.15537/smj.2024.45.5.20231019

Abdullah Ayed, Shahzada Khalid Sohail, Syeda Fatima Rizvi, Raed I Alwadai

引用次数: 0

Strengthened global capacities on climate change and health: WHO training in Madrid. 加强气候变化与健康方面的全球能力：世界卫生组织马德里培训。

IF 1.6 4区医学

Saudi Medical Journal Pub Date : 2024-05-01

引用次数: 0

Molecular epidemiology and molecular typing methods of Acinetobacter baumannii: An updated review. 鲍曼不动杆菌的分子流行病学和分子分型方法：最新综述。

IF 1.6 4区医学

Saudi Medical Journal Pub Date : 2024-05-01 DOI: 10.15537/smj.2024.45.5.20230886

Razique Anwer

引用次数: 0

Can artificial intelligence techniques help clinicians assess and treat patients with bone fractures? 人工智能技术能否帮助临床医生评估和治疗骨折患者？

IF 1.6 4区医学

Saudi Medical Journal Pub Date : 2024-05-01

引用次数: 0

Effect of cortisol and glycosylated-hemoglobin levels on mortality in intensive care unit. 皮质醇和糖化血红蛋白水平对重症监护室死亡率的影响。

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2024-05-01 DOI: 10.15537/smj.2024.45.5.20240076

Oznur Sen, Ugur Uzun, Nurdan Aydin, Isil Guldogan

{"title":"Effect of cortisol and glycosylated-hemoglobin levels on mortality in intensive care unit.","authors":"Oznur Sen, Ugur Uzun, Nurdan Aydin, Isil Guldogan","doi":"10.15537/smj.2024.45.5.20240076","DOIUrl":"10.15537/smj.2024.45.5.20240076","url":null,"abstract":"Objectives: To research the effects of blood cortisol and hemoglobinA1c (HBA1C) levels on mortality in patients admitted to the intensive care unit (ICU) and whether these factors could be used as reliable indicators for mortality risk assessment in these patients.Methods: After receiving approval from the ethics committee, 79 patients admitted to ICU were included in the study. From patient files, we collected data on demographics (age, gender), presence of diabetes mellitus, and levels of cortisol, HbA1C, glucose, and lactate measured during hospitalization, along with acute physiology and chronic health evaluation (APACHE) II scores calculated within the first 24 hours. In our study, we planned to investigate the relationship between patients' cortisol and HbA1C levels and mortality.Results: A total of 79 patients were included in the study. The mortality rate of the patients included in the study was 65.8%. In the model established with all variables, only cortisol level (p=0.017) and APACHE II score (p=0.005) were defined to affect mortality.Conclusion: Cortisol levels at the time of admission to the ICU were found to affect mortality and can be considered a predictive factor, while HBA1C levels showed no such effect. Our findings indicate that neither cortisol nor HBA1C levels had an impact on the duration of mechanical ventilation or length of stay in the ICU.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140909258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Building a healthy future for all: A roadmap for healthcare equity in Saudi Arabia. 为所有人打造健康的未来：沙特阿拉伯医疗保健公平路线图。

IF 1.6 4区医学

Saudi Medical Journal Pub Date : 2024-05-01 DOI: 10.15537/smj.2024.45.5.20240093

Yasser Ketab Alotaibi

引用次数: 0

Rheumatology research in Arab countries. 阿拉伯国家的风湿病学研究。

IF 1.6 4区医学

Saudi Medical Journal Pub Date : 2024-05-01 DOI: 10.15537/smj.2024.45.5.20240362

Ali S M Jawad, Georges El Hasbani, Imad Uthman

引用次数: 0

Clinical presentation and outcomes of patients with rhabdomyolysis: A tertiary care center experience. 横纹肌溶解症患者的临床表现和预后：三级医疗中心的经验。

IF 1.6 4区医学

Saudi Medical Journal Pub Date : 2024-05-01 DOI: 10.15537/smj.2024.45.5.20230560

Mohammed Tawhari, Abdulaziz Aldalaan, Rahaf Alanazi, Sarah Aldharman, Turki Alnafisah, Nawaf Alawad, Abdullah M Alhejji, Abdulrahman Yousef Alhabeeb, Moustafa S Alhamadh

{"title":"Clinical presentation and outcomes of patients with rhabdomyolysis: A tertiary care center experience.","authors":"Mohammed Tawhari, Abdulaziz Aldalaan, Rahaf Alanazi, Sarah Aldharman, Turki Alnafisah, Nawaf Alawad, Abdullah M Alhejji, Abdulrahman Yousef Alhabeeb, Moustafa S Alhamadh","doi":"10.15537/smj.2024.45.5.20230560","DOIUrl":"10.15537/smj.2024.45.5.20230560","url":null,"abstract":"Objectives: To evaluate the clinical and laboratory features, complications, and outcomes of patients with rhabdomyolysis in the Saudi population.Methods: Retrospectives descriptive study of adult patients who presented to King Abdulaziz Medical City (KAMC) withrhabdomyolysis between January 2016 and December 2022.Results: Most of the participants (84.5%) were male, with a median age of 41 years and a body mass index of 26.5 kg/m2. Medications, mainly statins (22.4%) and illicit drugs (15.5%), constituted the root causes of rhabdomyolysis in the cohort (44.8%). The most common presenting complaints were myalgia (63.8%) and fatigue (37.9%). More than one-third of the participants (32.8%) developed AKI, with 3 patients requiring temporary hemodialysis, and only 8.6% developed acute liver failure (ALF). Intensive care unit (ICU) admission was required for 10 patients (17.2%), and the overall mortality rate was 8.6%. Patients who developed complications (composite outcomes of AKI, ALF, multiorgan failure, or death) had significantly reduced kidney function and higher levels of blood urea nitrogen, anion gap, and uric acid upon admission than those who did not.Conclusion: This study offers a thorough understanding of clinical and laboratory features, causes, complications, and outcomes of rhabdomyolysis among Saudi patients. The insights gained enhance our understanding of rhabdomyolysis within this population, providing a foundation for future research and improvements in clinical management.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140909239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0