Saudi Medical Journal最新文献_第9页

Severe childhood poisoning caused by Ferraga practices. Data from the Moroccan Poison Control and Pharmacovigilance Centre. Ferraga 做法导致的儿童严重中毒。数据来自摩洛哥毒物控制和药物警戒中心。

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240564

Mina Talib, Naima Rhalem, Abderrahim Chebat, Abdelmajid Soulaymani, Rachida Soulaymani-Bencheikh, Souad Skalli, Jamila Dahmani

{"title":"Severe childhood poisoning caused by Ferraga practices. Data from the Moroccan Poison Control and Pharmacovigilance Centre.","authors":"Mina Talib, Naima Rhalem, Abderrahim Chebat, Abdelmajid Soulaymani, Rachida Soulaymani-Bencheikh, Souad Skalli, Jamila Dahmani","doi":"10.15537/smj.2024.45.11.20240564","DOIUrl":"10.15537/smj.2024.45.11.20240564","url":null,"abstract":"Objectives: To highlight the complications associated with the products and practice of healers \"Ferraga\" who treat young children using traditional Moroccan pharmacopoeia.Methods: This is a retrospective analysis of cases of products and practice of \"Ferraga\" intoxication in young children reported to the Moroccan Poison Control and Pharmacovigilance Center (MPCPC), Rabat, Morocco, from 2010-2020.Results: During the study period, 24 cases of products and practice of \"Ferraga\" poisoning were reported to MPCPC, Rabat, Morocco. The average age of the patients was 2.48 years. The oral route was noted in 21 cases. The vast majority of patients (23 cases) exhibited symptoms upon admission, predominantly of digestive (16 cases), respiratory (3 cases), and neurological (4 cases). However, 29.16% of patients presented with both digestive and respiratory symptoms, 20.83% had digestive and neurological symptoms, and 4 cases manifested all 3 types of symptoms. The outcome was positive in 18 patients and fatal in 2 infants.Conclusion: Products and practice of \"Ferraga\" poisoning in children remains a major health problem. It is crucial to implement a strategy to combat this type of practice in order to reduce the prevalence of such poisoning.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1277-1280"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Burnout among emergency and surgery residents: An exploration of contributing factors and implications. 急诊和外科住院医师的职业倦怠：对诱因和影响的探讨。

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240436

Mohammed S Bu Bshait, Ahmad A Al Abdulqader, Abdullah K Almaqhawi, Haytham M Alarfaj, Nawaf A Al Khashram, Alwaleed A Alqarni, Mohammed K Alghamdi, Abdulrahman A Alshehri, Saad N Alharthi, Ali M Alajmi, Abdullah E Al-Melaifi

{"title":"Burnout among emergency and surgery residents: An exploration of contributing factors and implications.","authors":"Mohammed S Bu Bshait, Ahmad A Al Abdulqader, Abdullah K Almaqhawi, Haytham M Alarfaj, Nawaf A Al Khashram, Alwaleed A Alqarni, Mohammed K Alghamdi, Abdulrahman A Alshehri, Saad N Alharthi, Ali M Alajmi, Abdullah E Al-Melaifi","doi":"10.15537/smj.2024.45.11.20240436","DOIUrl":"10.15537/smj.2024.45.11.20240436","url":null,"abstract":"Objectives: To assess the prevalence of burnout among emergency and surgical residents and explore the associated factors.Methods: This study was carried out at King Faisal University, Al Hofuf, Saudi Arabia, through the period from January to march 2024. A cross-sectional survey design was employed, utilizing the Maslach burnout inventory-human services survey and the resilience scale-14 to measure burnout and resilience. The survey included demographic information, health-related questions, and specific burnout-related items. Descriptive statistics, frequency distributions, and inferential analyses were carried out to explore the relationships between burnout, demographic factors, and resilience.Results: The study revealed a diverse representation across demographic factors, with variations in burnout prevalence. Approximately 63% of participants reported experiencing burnout, with high levels of emotional exhaustion (55%) and depersonalization (28%). Resilience levels varied across different demographic characteristics. Significant associations were found between burnout and factors such as gender, marital status, having children, specialty, length of experience, and enrollment in postgraduate programs.Conclusion: The findings underscore the urgent need for targeted interventions to address burnout in healthcare professionals. The nuanced relationships between burnout, resilience, and demographic factors highlight the importance of tailored strategies to mitigate burnout effectively. Addressing burnout is crucial not only for the well-being of healthcare professionals but also for maintaining high-quality patient care.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1270-1276"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An 8-year review of upper limb congenital differences at a teaching hospital in Jordan: A retrospective study. 约旦一家教学医院上肢先天性差异的 8 年回顾：一项回顾性研究。

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240602

Omar Q Samarah, Ayham M Odeh, Zaid M Alkhadire, Roaa H Abu Hejleh, Yazeed Y Diab, Leen N Yousef, Yazan S Hammad, Mohamad S Yasin, Ahmad A Abu Halaweh

{"title":"An 8-year review of upper limb congenital differences at a teaching hospital in Jordan: A retrospective study.","authors":"Omar Q Samarah, Ayham M Odeh, Zaid M Alkhadire, Roaa H Abu Hejleh, Yazeed Y Diab, Leen N Yousef, Yazan S Hammad, Mohamad S Yasin, Ahmad A Abu Halaweh","doi":"10.15537/smj.2024.45.11.20240602","DOIUrl":"10.15537/smj.2024.45.11.20240602","url":null,"abstract":"Objectives: To review the types of upper limb congenital differences in patients seen in a tertiary hospital in Jordan and to evaluate the effectiveness of the Oberg-Manske-Tonkin (OMT) system.Methods: The medical charts and the X-rays of 222 patients with upper limb congenital differences were reviewed. All these cases were categorized using the OMT classification system.Results: A careful review of the medical charts identified 222 patients with 295 upper extremity anomalies. The prevalence was 45/10000 patients. The mean age of the patients was 6.18±5.5 years, with a higher prevalence in males 54.1%. most cases were malformations 176 (79%) and of these the radial polydactyly was the most common (18.5%). A total of 28 cases of dysplasia were identified. A total of 15 (6.7%) patients were diagnosed with syndromes, of which Poland syndrome showed the highest frequency at 2.3% of the total. The least presentation was for the deformation anomalies (1.4%).Conclusion: The malformation category constituted most of the congenital upper extremity difference in this study. Radial polydactyly was the most common in this category. Considering the regional differences, the need for a well-established healthcare infrastructure is a vital step toward managing and improving the outcomes of these patients.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1265-1269"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accuracy of imaging of BI-RADS 4 subcategorizations in breast lesion diagnosis: Radiologic-pathologic correlation. BI-RADS 4 亚分类在乳腺病变诊断中的成像准确性：放射学与病理学相关性。

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240001

Hadeel A Ghunaim, Rana E Alatawi, Walaa M Borhan, Tareef S Daqqaq, Ayman S Alhasan, Mervat M Aboualkheir, Reem M Elkady

{"title":"Accuracy of imaging of BI-RADS 4 subcategorizations in breast lesion diagnosis: Radiologic-pathologic correlation.","authors":"Hadeel A Ghunaim, Rana E Alatawi, Walaa M Borhan, Tareef S Daqqaq, Ayman S Alhasan, Mervat M Aboualkheir, Reem M Elkady","doi":"10.15537/smj.2024.45.11.20240001","DOIUrl":"10.15537/smj.2024.45.11.20240001","url":null,"abstract":"Objectives: To correlate breast imaging-reporting and data system (BI-RADS) category 4 lesions with histopathology results to assess the accuracy of subcategorization.Methods: A retrospective study was carried out from September 2021 to June 2022. A total of 247 breast lesions were reviewed categorized as BI-RADS 4 using ultrasound (US) and digital mammography. Feature analysis of the lesions were obtained using BI-RADS terminology and assigned to subcategories (4A, 4B, and 4C). Pathological analysis was carried out on tissue obtained through US-guided core biopsy. A p-value of <0.05 was considered significant.Results: Of the 247 lesions, 135 were categorized as subcategory 4A, 68 as 4B, and 44 as 4C. Overall, 41 (16.6%) had malignant lesions, while 206 (83.4%) had benign lesions. The mean age of the patients with benign versus malignant lesions was (43.18±14.02 vs. 51.24±14.15 years; p<0.001). Mean size of benign versus malignant lesions was (1.93±1.65 vs. 3.82±3.89 cm; p<0.001). Findings were compared with histopathology, and the positive predictive value fell within the reference range for subcategories 4C (>70%). High reliability was observed between the 2 readers, with a weighted Cohen's Kappa value of 0.79 (0.73-0.85). Significant disagreements in the assignment of features on radiological lesion characterization were observed between the 2 readers regarding lesion density, shape, echo pattern, vascularity, and borders.Conclusion: The results of this study contribute to the existing body of knowledge, emphasizing the need for standardized guidelines for the characterization of BI-RADS 4 subcategories and improved diagnostic accuracy in the management of breast lesions.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1228-1237"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dense breast tissue in screened postmenopausal women: Prevalence and determinants. 绝经后妇女筛查中的致密乳腺组织：发病率和决定因素

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240571

Ibrahem H Kanbayti

{"title":"Dense breast tissue in screened postmenopausal women: Prevalence and determinants.","authors":"Ibrahem H Kanbayti","doi":"10.15537/smj.2024.45.11.20240571","DOIUrl":"10.15537/smj.2024.45.11.20240571","url":null,"abstract":"Objectives: To explore the prevalence of dense breast tissue among screened postmenopausal women and identify the factors influencing breast density in this population.Methods: A retrospective analysis of data from postmenopausal women screened for breast cancer in Jeddah, Saudi Arabia, between April 2017 and June 2021 was carried out. Breast density was subjectively assessed, and influencing factors were retrieved from the hospital information system. Proportions were used for descriptive analysis, and binary logistic regression was used to identify the determinants of dense breast tissue.Results: Only 12.7% of the postmenopausal women had dense breast tissue. Non-Saudi women (odds ratio [OR]=1.95, 95% confidence interval [CI]: [1.07-3.54], p=0.02) and those who did not breastfeed (OR=2.75, 95% CI: [1.33-5.53], p=0.006) had a greater likelihood of having dense breast tissue. Women who had never been pregnant (nulliparous) were 4 times more likely to have dense breast tissue than those who had been pregnant (parous; p<0.001). Additionally, women with fewer children had a higher chance of dense breast tissue (OR=2.58, 95% CI: [1.23-5.40], p=0.01).Conclusion: The prevalence of dense breast tissue among screened postmenopausal women was low. However, certain factors increase the risk of having dense tissue in this population, including not being Saudi Arabian, never having breastfed, being nulliparous, and having fewer children.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1238-1244"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

WHO launches global strategic plan to fight rising dengue and other Aedes-borne arboviral diseases. 世卫组织启动全球战略计划，抗击登革热和其他伊蚊传播的虫媒病毒疾病。

IF 1.7 4区医学

Saudi Medical Journal Pub Date : 2024-11-01

引用次数: 0

Development and cultural adaptation of the Saudi pediatric speech intelligibility test. 沙特儿科语言清晰度测试的开发和文化适应。

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240539

Medhat Yousef, Tamer Mesallam, Yassin Abdelsamad, Sara Alkhamiss, Tahani Alotaibi, Shahad Alsanosi, Ayna Almasaad, Abdulrahman Alsanosi

{"title":"Development and cultural adaptation of the Saudi pediatric speech intelligibility test.","authors":"Medhat Yousef, Tamer Mesallam, Yassin Abdelsamad, Sara Alkhamiss, Tahani Alotaibi, Shahad Alsanosi, Ayna Almasaad, Abdulrahman Alsanosi","doi":"10.15537/smj.2024.45.11.20240539","DOIUrl":"10.15537/smj.2024.45.11.20240539","url":null,"abstract":"Objectives: To report the development and administration of the Saudi pediatric speech intelligibility (SPSI) test.Methods: This study was carried out at King Abdullah Ear Specialist Center, King Saud University, Riyadh, Saudi Arabia, between 2021 and 2023. A pilot study was carried out in 5 regions of Saudi Arabia including 100 normal hearing children aged 7-11 years old, with 20 children from each region. The final test materials were voice-recorded by a native Saudi radio announcer, and a software-based application for administering the SPSI was developed.Results: During the pilot study, minor adjustments were carried out to the test for more clarity. The developed SPSI software is an android-based application that includes features like automatic result calculation, data saving, and individual user accounts for examiners to review results. The SPSI test comprises 4-word cards and 2 sentence cards, each with 5 pictures, and operates in 3 modes: quiet, background noise, and competing sentences.Conclusion: The SPSI test has been developed in an android-based software using the Saudi local dialects. It can facilitate comprehensive and accurate assessment of speech intelligibility, particularly in children with hearing impairments.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1260-1264"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systemic immune-inflammatory index and platelet-to-lymphocyte ratio in intrahepatic cholestasis of pregnancy. 妊娠肝内胆汁淤积症的全身免疫炎症指数和血小板与淋巴细胞比率

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240760

Nihal Çallıoğlu, Güray Tuna, Özden Tandoğan, Fırat Ersan, Selçuk Atalay, Kübra K Bilirer

{"title":"Systemic immune-inflammatory index and platelet-to-lymphocyte ratio in intrahepatic cholestasis of pregnancy.","authors":"Nihal Çallıoğlu, Güray Tuna, Özden Tandoğan, Fırat Ersan, Selçuk Atalay, Kübra K Bilirer","doi":"10.15537/smj.2024.45.11.20240760","DOIUrl":"10.15537/smj.2024.45.11.20240760","url":null,"abstract":"Objectives: To investigate the role of systemic immune-inflammation index (SII) in the diagnosis and severity of intrahepatic cholestasis of pregnancy (ICP).Methods: This case-control research involved 173 pregnant women with ICP and 266 gestational age-related healthy pregnant women as the control group. Criteria for diagnosing ICP were acceptance of increased serum total bile acid (TBA) levels (≥10 μmol/L). The mild ICP group (n=109) had TBA levels ranging between 10-39 µmol/l, while the severe ICP group (n=64) had a minimum TBA level above 40 µmol/l. Sociodemographic data, laboratory results, and SII values were compared between groups. Cut-off values were calculated to predict ICP. The SII was calculated as the platelet count × neutrophil count/lymphocyte count.Results: The leukocyte and neutrophil counts were lower (p<0.01), and the monocyte count was higher (p=0.026) in the severe ICP group compared to the controls. The platelet-to-lymphocyte ratio (PLR) was higher in mild ICP groups than in controls (p<0.01). The optimum PRL cut-off value was 126.2238, with a sensitivity of 57.2% and specificity of 57.1%.Conclusion: Elevated SII values support the evidence for the inflammatory properties of ICP but do not aid in diagnosing and determining its severity. Platelet-to-lymphocyte ratio may be a useful marker in determining ICP.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1217-1222"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Central nervous system manifestations of tuberous sclerosis complex: A single centre experience in Qatar. 结节性硬化症复合体的中枢神经系统表现：卡塔尔单一中心的经验。

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240444

Munira Aden, Mahmoud O Fawzi, Debra Prosser, Muhammad Ather, Mehak Raja, Moegamad A Ederies, Khalid Al-Kharazi, Ata U Maaz

{"title":"Central nervous system manifestations of tuberous sclerosis complex: A single centre experience in Qatar.","authors":"Munira Aden, Mahmoud O Fawzi, Debra Prosser, Muhammad Ather, Mehak Raja, Moegamad A Ederies, Khalid Al-Kharazi, Ata U Maaz","doi":"10.15537/smj.2024.45.11.20240444","DOIUrl":"10.15537/smj.2024.45.11.20240444","url":null,"abstract":"Objectives: To review the clinical and radiological correlation of the central nervous system manifestations of tuberous sclerosis complex (TSC).Methods: All patients under the age of 18 years with TSC seen at the Department of Pediatrics, Sidra Medicine, Doha, Qatar, between January 2003 and February 2021 were included in this retrospective study. Severity of epilepsy was determined using the early childhood epilepsy severity score (E-CHESS) tool.Results: The study sample included 38 patients (50% male), 8 (21%) of whom were native to Qatar. The median age at diagnosis was 4 (range: 0-72) months. A family history of TSC was present in 10 (26%) cases, while 33 (86%) patients had a TSC2 gene mutation. Common presentations included seizures (79%), rhabdomyoma (26%), and developmental delay (13%). On MRI scans, cortical tubers were seen in all patients, subependymal nodules in 37 (97%), and subependymal giant cell astrocytoma was diagnosed in 8 (21%) cases. A total of 30 children developed epilepsy, 9 of whom had favorable and 21 had unfavorable E-CHESS scores, and 6 required pharmaceutical management. A total of 13 children were diagnosed with autistic spectrum disorder and 12 with attention deficit hyperactivity disorder.Conclusion: Multidisciplinary management and further research is needed to optimize the care and quality of life of TSC affected individuals and their families.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1245-1252"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive functions among school-going children and adolescents with type 1 diabetes mellitus: Matched case-control cross-sectional study. 1 型糖尿病学龄儿童和青少年的认知功能：匹配病例对照横断面研究。

IF 16.4 4区医学

Saudi Medical Journal Pub Date : 2024-11-01 DOI: 10.15537/smj.2024.45.11.20240509

Sultan A Meo, Metib Alotaibi, Narmeen Shaikh, Reem AlKhalifah

{"title":"Cognitive functions among school-going children and adolescents with type 1 diabetes mellitus: Matched case-control cross-sectional study.","authors":"Sultan A Meo, Metib Alotaibi, Narmeen Shaikh, Reem AlKhalifah","doi":"10.15537/smj.2024.45.11.20240509","DOIUrl":"10.15537/smj.2024.45.11.20240509","url":null,"abstract":"Objectives: To investigate the cognitive performance of Saudi children and adolescents with type 1 diabetes mellitus (T1DM) compared to matched control groups.Methods: A total of 64 participants (32 T1DM patients and 32 control), matched with age, gender, ethnicity, education, and body mass index were recruited. Cognitive functions were investigated using a highly reliable and valid \"Cambridge neuropsychological test automated battery\". The attention switching task (AST) and choice reaction time (CRT) test were carried out to evaluate the cognitive functions.Results: The cognitive test parameters AST mean correct latency, AST mean correct latency (congruent), AST mean correct latency (incongruent), and CRT mean correct latency were significantly delayed in the T1DM group compared to their control group (p<0.0001). Moreover, the control group did significantly better on the cognitive test parameters AST and CRT than the T1DM children and adolescents with hemoglobin A1c (HbA1C) ≥8% group (p<0.01).Conclusion: The findings demonstrate a delay in cognitive performance among children and adolescents with T1DM. Importantly, elevated HbA1C levels and duration of disease were associated with reduced cognitive functions. The present study findings highlight the importance of stringent glycemic management in children and adolescents with T1DM. The findings can support physicians and policymakers not only to prevent microvascular complications but also to mitigate potential cognitive deficits among children and adolescents with T1DM.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"45 11","pages":"1253-1259"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0