Saudi Medical Journal最新文献

{"title":"Drug-coated balloons versus conventional percutaneous transluminal angioplasty for treatment-naïve dysfunctional arteriovenous fistulas.: A 10-year single center retrospective study.","authors":"Abdulaziz AlQubaisi, Mohammad Arabi, Yousof AlZahrani, Omar Bashir","doi":"10.15537/smj.2024.45.7.20230852","DOIUrl":"10.15537/smj.2024.45.7.20230852","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the primary patency and restenosis rates in treatment naieve dialysis arteriovenous fistulas (AVFs) after drug-coated balloons (DCB) versus plain balloon angioplasty (PTA).</p><p><strong>Methods: </strong>This retrospective study included 157 patients who underwent AVF angioplasty for treatment-native AVF stenosis between January 2012 to 2022. The fistulas were Brachiocephalic (75%), Brachiobasilic (17%), and radiocephalic (8%). The index intervention was with either DCB or percutaneous transluminal angioplasty (PTA) with subsequent follow up. Patients with central venous stenosis, thrombosed fistula, fistula stents, AV graft or surgical intervention after the index procedure were excluded.</p><p><strong>Results: </strong>Arteriovenous fistula angioplasty was done in 28 patients using DCB and in 129 patients using PTA. A total of 108 patients presented with a single stenosis, 42 with 2 stenoses, and 7 with 3 stenoses. The location of these stenoses was in the venous outflow (57%), the juxta anastomotic segment (31%), and cephalic arch (12%). The median time to re-intervention for the PTA was 216 days compared to 304 days for the DCB (<i>p</i>=0.079). Primary patency at 6 months was 60.4% for PTA and 75% for DCB (<i>p</i>=0.141) CONCLUSION: Although DCB angioplasty of treatmentnaïve dysfunctional AVF tends to improve the time to intervention and 6-month primary patency compared to PTA, this difference did not reach statistical significance.</p>","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"WHO unveils a digital health promoter harnessing generative AI for public health.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the correlation between the degree of tricuspid regurgitation and pulmonary hypertension: A comprehensive study.","authors":"Jamilah S AlRahimi, Yasser M Ismail, Noor A Aljubairi, Nawal W Kutob, Ghadi S Bakulka, Ruqayyah A Ahmed, Fatima A Ahmed, Ali A Haneef","doi":"10.15537/smj.2024.45.6.20240071","DOIUrl":"10.15537/smj.2024.45.6.20240071","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the relationship between severity of tricuspid regurgitation (TR) and pulmonary hypertension.</p><p><strong>Methods: </strong>Cross-sectional study of 118 patients with pulmonary hypertension was carried out at a single center in Jeddah, Saudi Arabia, between 2018-2021. Patients who had pulmonary or tricuspid valves organic diseases, previously undergone tricuspid or pulmonary valve surgeries, had permanent pacemakers or critically ill were excluded.</p><p><strong>Results: </strong>A high proportion of patients were women (n=100, 85%) and obese (n=57, 48%). Patients with more than mild TR had higher systolic pulmonary artery pressure (sPAP) than those with trivial or mild regurgitation (<i>p</i><0.001). There was a significant association between severity of TR (<i>p</i><0.001) and right chambers size (<i>p</i>=0.001). Furthermore, pulmonary artery pressure (PAP) was significantly higher in patients with mild right ventricular impairment (<i>p</i>=0.001).</p><p><strong>Conclusion: </strong>Increase in degree of TR and right atrial size were predictors of elevated sPAP. Our findings highlight the interplay among TR, right heart size, ventricular function, and PAP. Understanding these associations can aid in risk stratification, monitoring disease progression, and potentially guiding treatment in those patients.</p>","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do digital health information searches of individuals with chronic diseases affect health literacy and patient empowerment? A path analysis.","authors":"Şenay Şener, Seda Göger","doi":"10.15537/smj.2024.45.6.20240158","DOIUrl":"10.15537/smj.2024.45.6.20240158","url":null,"abstract":"<p><strong>Objectives: </strong>To analyze the relationship between chronically ill patients' behaviors in acquiring and verifying health information from a digital environment with health literacy and patient empowerment using a structural equation modeling approach.</p><p><strong>Methods: </strong>This study was carried out in a public hospital in Turkey between February and May 2023. The study consisted of 365 participants and used descriptive and correlation-based designs for statistical analyses. It also executed computations for descriptive statistics and correlations to carry out a path analysis to assess model fitness and to identify direct and indirect effects.</p><p><strong>Results: </strong>This study identified that Web 1.0 and health information acquisition and digital verification variables statistically and significantly affected access to information, understanding information, appraisal (valuing)/evaluation, and application/use variables. The study also found that access to information variables was statistically significant on identity/identicalness, self-control, decision-making, and recognition and comprehension. The tested model fit the data well and adequately explained the direct effects of the variables.</p><p><strong>Conclusion: </strong>The study concluded by suggestively improving the chronically ill patients' media or digital literacy levels through special training to stimulate their internet use effectively.</p>","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: Effect of cortisol and glycosylated-hemoglobin levels on mortality in intensive care unit.","authors":"Ghadah B Alanazi, Maysah G Amer","doi":"10.15537/smj.2024.45.6.20240443","DOIUrl":"10.15537/smj.2024.45.6.20240443","url":null,"abstract":"","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of candidemia risk factors and <i>Candida</i> species distribution in intensive care units among patients with and without COVID-19.","authors":"Cemile Uyar, Emel Yıldız, Özlem Genç, Öznur Ak, Emel Koçak, Sevil Alkan, Canan Balcı, Pınar Korkmaz, Duru Mıstanoğlu Özatağ, Halil Aslan","doi":"10.15537/smj.2024.45.6.20240102","DOIUrl":"10.15537/smj.2024.45.6.20240102","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the risk variables related to the types of candidemia for each patient, who was admitted into the intensive care unit regardless of the patient with or without complete diagnosis of COVID-19, during the period of March 2019 to December 2022.</p><p><strong>Methods: </strong>The evaluation comparison of demographic and clinical data of COVID-19 positive and negative patients with candidemia confirmed in blood, 113 cases were assessed. Variables such as gender, age, age of hospitalization, history of hospitalization, concurrently infection, The acute physiology and chronic health evaluation-II scores, comorbidity checking, intubation, central venous catheter use, parenteral nutrition use, steroid use, antibiotic use, lymphopenia, and laboratory variables were evaluated. <i>Candida</i> species distribution, antifungal susceptibility in blood culture were determined.</p><p><strong>Results: </strong>Coronavirus disease-19 was present in 62.8% of cases confirmed candidemia, and these cases were significantly different from COVID-19 negative cases. Significance was found in more intubation, central venous catheter use, parenteral nutrition, and steroid therapy in Group 2. There was no significance with species distribution and associated infection. In total, COVID-19 positive had higher hemoglobin, aspartate aminotransferase, alanine transaminase, and white blood cell levels, which may be associated with the possibility of revealing and controlling candidemia.</p><p><strong>Conclusion: </strong><i>Candida albicans</i> and <i>Candida Parapsilosis</i> (<i>C. parapsilosis</i>) are the species seen in infected COVID-19 patients, while C. parapsilosis and <i>Candida tropicalis</i> are found in non-COVID-19 ones. Risk factors were intubation, parenteral nutrition, central venous catheter, and steroid in the COVID-19 group.</p>","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of sarcopenia and vitamin D levels on the severity of lower urinary tract symptoms in older males.","authors":"Deniz M Surmeli, Hulusi C Karpuzcu, Volkan Atmis, Caglar Cosarderelioglu, Ahmet Yalcin, Murat Varli, Sevgi Aras","doi":"10.15537/smj.2024.45.6.20240166","DOIUrl":"10.15537/smj.2024.45.6.20240166","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the impact of sarcopenia and vitamin D levels on the severity of lower urinary tract symptoms (LUTS).</p><p><strong>Methods: </strong>A total of 193 male patients, aged 60 years and above, who visited the geriatric outpatient clinic at Ibn-i Sina Hospital in Ankara, Turkey, between December 2019 and March 2021, were enrolled. Sarcopenia was diagnosed according to the criteria set by the European Working Group on Sarcopenia in Older People. The presence and severity of lower urinary tract symptoms were assessed using the International Prostate Symptom Score questionnaire, categorizing symptom severity as mild or moderate-to-severe.</p><p><strong>Results: </strong>The median patient age was 71 years (range: 66-77). Sarcopenia affected 24.9% of the population studied. Mild LUTS was observed in 43.5% and moderate-to-severe LUTS was observed in 56.5% of patients. Sarcopenia prevalence was significantly higher in the individuals with moderate-to-severe LUTS compared to those with mild-LUTS (<i>p</i>=0.021). After adjusting for Charlson comorbidity index and age, only vitamin D levels were significantly associated with increased odds of moderate-to-severe LUTS (odds ratio [OR]=0.95, 95% confidence interval [CI]: [0.92-0.98], <i>p</i>=0.002). Sarcopenia was not significantly associated with the severity of LUTS (OR=2.04, 95% CI: [0.94-4.45], <i>p</i>=0.070). An inverse linear trend was observed between quartiles of 25 (OH) vitamin D and LUTS severity. As 25 (OH)vitamin D levels increased, the proportion of patients with moderate-to-severe LUTS decreased (<i>p</i>=0.023).</p><p><strong>Conclusion: </strong>Sarcopenia did not significantly impact LUTS severity, but low vitamin D levels were associated with moderate-to-severe LUTS.</p>","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of thyroid disorders among the diabetic population in Arar, Saudi Arabia.","authors":"Haider O Elmisbah, Riyad Y Laham, Hafiz O Almisbah, Hadeel T Alanazi, Taif A Alanazi, Raghad M Alanzi, Wejdan A Aldahmashi, Anshoo Agarwal, Rashad Q Othman","doi":"10.15537/smj.2024.45.6.20240144","DOIUrl":"10.15537/smj.2024.45.6.20240144","url":null,"abstract":"<p><strong>Objectives: </strong>To study the prevalence of thyroid disorders (TDs) among the diabetic population in Arar, Saudi Arabia.</p><p><strong>Methods: </strong>A cross-sectional design study carried out in Arar, northern province of Saudi Arabia, from October 2023 to January 2024. A structured questionnaire was used to collect the data. From the diabetic population aged over 18 years old.</p><p><strong>Results: </strong>A total of 501 participants were enrolled. Most fall within the 20-35 age range, comprising 36.5% of the sample. Vitamin D deficiency appears to be the most prevalent comorbid condition. Following closely behind is vitamin B12 deficiency; hypertension and high blood lipids also show notable prevalence rates, affecting 10.5-22.1% of the population. In terms of diabetes, 42.8% of the population has been diagnosed with the condition. Among those with diabetes, the majority (67.6%) have been diagnosed with the second type, while 32.4% have the first type. There is an association between diabetes and TDs, with 51.3% of participants reporting this.</p><p><strong>Conclusion: </strong>The findings indicate that the adults in Arar, Saudi Arabia, lack some knowledge of TDs and their relationship to diabetes.</p>","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma.","authors":"Ramy Samargandi, Mathilde Bernard, Elodie Miquelestorena-Standley, Louis Romée Le Nail","doi":"10.15537/smj.2024.45.6.20230720","DOIUrl":"10.15537/smj.2024.45.6.20230720","url":null,"abstract":"<p><p>Chondroblastoma is a rare benign cartilaginous tumor that accounts for approximately 1% of bone tumors, but it can be associated with lung metastasis in extremely rare cases, leading to a poor prognosis and death. Herein, we report the case of a 19-year-old male patient who presented with an aggressive chondroblastoma of the proximal humerus and bilateral lung metastasis. The patient was treated with wide local resection, partial metastasectomy, and denosumab. Denosumab treatment was effective in controlling metastatic progression and preventing local recurrence.</p>","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How does aspirin help prevent colorectal cancer development and progression?","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}