Rasayan Journal of Chemistry最新文献_第4页

SYNTHESIS OF LiFe1-xNixPO4/C USING THE REFLUX WITH MICROWAVE IRRADIATION METHOD 微波辐照回流法制备LiFe1-xNixPO4/C

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628164

D. Purwaningsih, H. Sutrisno, K. Sugiyarto, C. Kusumawardani, N. A. Kusumaningrum

引用次数: 0

SIMULTANEOUS REVERSE PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP-HPLC) ESTIMATION OF AZELASTINE HYDROCHLORIDE, FLUTICASONE PROPIONATE, AND PHENYL ETHYL ALCOHOL IN DYMISTA (MEDA) NASAL SPRAY 反相高效液相色谱(rp-hplc)同时测定盐酸氮唑elastine、丙酸氟替卡松和苯乙醇在dymista (meda)鼻喷雾剂中的含量

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1616916

A. Gupta, P. Singour, S. K. Jain

{"title":"SIMULTANEOUS REVERSE PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP-HPLC) ESTIMATION OF AZELASTINE HYDROCHLORIDE, FLUTICASONE PROPIONATE, AND PHENYL ETHYL ALCOHOL IN DYMISTA (MEDA) NASAL SPRAY","authors":"A. Gupta, P. Singour, S. K. Jain","doi":"10.31788/rjc.2023.1616916","DOIUrl":"https://doi.org/10.31788/rjc.2023.1616916","url":null,"abstract":"This work reported a reverse phase-high performance liquid chromatography method for quantitative estimation of Azelastine Hydrochloride, Fluticasone Propionate, and Phenylethyl Alcohol in Nasal Spray formulation. The assay involved an isocratic elution of these components by using Intersil Octadecylsilane (C18) column (25 cm x 4.6 mm x 5 μm) using mobile phase composition of Buffer: Solvent Mixture (40:60 %v/v) and pH adjusted to 6.5 with dilute orthophosphoric acid. The flow rate was 1.4 mLmin-1 and the analytes are monitored at 254 nm. Separation was completed within 20 minutes. Calibration curves were linear with correlation coefficient more than 0.99 over a concentration range of 50%, 75%, 100%, 125%, and 150% for Azelastine Hydrochloride, Fluticasone Propionate and Phenylethyl Alcohol. The method was proven to be accurate between 50 to 150% with 98 to 102 % recovery of the actives from a spiked placebo. The method was shown to be precise yielding acceptable results for the system reproducibility and method repeatability. All the validation parameters were within the acceptance range according to International Conference on Harmonization norms. The developed method is simple and rapid which could be applied for routine estimation of the formulation.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69409717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

QUALITY TEST OF CMC (CARBOXYMETHYL CELLULOSE) USING SEMI-BATCH REAKTOR 半间歇反应器法测定羧甲基纤维素的质量

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1626922

R. Futeri, S. Samah, G. R. Putri

{"title":"QUALITY TEST OF CMC (CARBOXYMETHYL CELLULOSE) USING SEMI-BATCH REAKTOR","authors":"R. Futeri, S. Samah, G. R. Putri","doi":"10.31788/rjc.2023.1626922","DOIUrl":"https://doi.org/10.31788/rjc.2023.1626922","url":null,"abstract":"Carboxymethyl Cellulose, one of the additives commonly used in the industrial sector, is carboxymethyl cellulose. The state of the art of this research is because no research makes a reactor to manufacture carboxymethyl cellulose. This study tested the quality of making carboxymethyl cellulose using a semi-batch reactor using samples of potential organic cellulose waste materials: durian seeds, taro rods, and bagasse. This sample has been used to make carboxymethyl cellulose in previous studies using a laboratory scale. Then compared, the manufacture of carboxymethyl cellulose using a reactor laboratory scale. From the result obtained, carboxymethyl cellulose from durian seeds, taro rod, and bagasse made on a laboratory scale and using a reactor has become carboxymethyl cellulose in quality number 1 and 2, which are commonly called carboxymethyl cellulose industrial grade and food chemical codex quality which met the minimum quality requirements by SNI 8762; 2019. Carboxymethyl cellulose from durian seeds, taro rod, and bagasse obtained from research that has been tested with FTIR, the spectra of the best results of carboxymethyl cellulose from durian seeds, taro rod, and bagasse can be seen in the picture there are similar peaks that appear indicates carboxymethyl cellulose durian seeds, carboxymethyl cellulose taro rod, and carboxymethyl cellulose bagasse produced in this study have the same chemical molecule as industrial grade and food chemical codex.1.2","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

POLYMERIC COMPOSITIONS TO INCREASE OIL RECOVERY 聚合物成分，提高石油采收率

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628295

A. Issa, O. K. Beisenbayev, U. Akhmedov, B. Smailov, M. Yessirkepova, A.Sh. Kydyraliyeva, Z. Artykova

引用次数: 0

ANTIOXIDANT ACTIVITY OF N-HEXANE, DICHLOROMETHANE, ETHYL ACETATE, AND METHANOL EXTRACTS OF Litsea cubeba Lour. BARKS 山苍子正己烷、二氯甲烷、乙酸乙酯和甲醇提取物的抗氧化活性。叫

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628238

A. Dalimunthe, M. Muhammad, M. Rafi, V. M. Syafma, F. Hulwani, I. Aprilliawati, D. Satria

{"title":"ANTIOXIDANT ACTIVITY OF N-HEXANE, DICHLOROMETHANE, ETHYL ACETATE, AND METHANOL EXTRACTS OF Litsea cubeba Lour. BARKS","authors":"A. Dalimunthe, M. Muhammad, M. Rafi, V. M. Syafma, F. Hulwani, I. Aprilliawati, D. Satria","doi":"10.31788/rjc.2023.1628238","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628238","url":null,"abstract":"Free radicals are molecules with unstable unpaired electrons and originate from environmental pollutants and from unhealthy people's lifestyles that reduce the quality of life in the presence of various degenerative diseases from premature aging, stroke, and even cancer. Antioxidants are used to neutralize, reduce and inhibit the formation of new free radicals in the body by becoming electron donors for free radicals so that free electrons in free radicals become paired and stop damage in the body. With the presence of antioxidant compounds, oxidative stress triggered by free radicals can be stabilized and neutralized to reduce the risk of damage to body cells. Indonesia is a country rich in spice plant resources. One type of spice plant that has the potential to be developed is Attarasa (Litsea cubeba Lour.) which is widely found in the North Tapanuli area. This plant contains essential oils in the fruit, stems, roots, and leaves. This makes all parts of this plant smell good. This study aimed to determine the antioxidant activity of a fraction of Litsea cubeba Lour. barks. The fraction with n-hexane, dichloromethane, ethyl acetate, and methanol as solvent. Antioxidant activities were determined with ABTS, CUPRAC, and O-Phenanthroline method. The data were analyzed using the Principle Component Analysis (PCA) multivariate exploration technique, which was analyzed using the Minitab software. The extracts were obtained IC50 values from the ABTS (395.65 ± 0.37; 344.78 ± 0.57; 30.37 ± 0.04; 283.07 ± 0.85); CUPRAC (220.77 ± 0.21; 144.50 ± 0.26; 10.00 ± 0.01; 11.13 ± 0.04); O-Phenanthroline (798.27 ± 0.06; 410.01 ± 0.23; 175.75 ± 0.25; 32.01 ± 0.03) respectively. While the total phenol was analyzed (23.56 ± 0.56; 2.63 ± 0.01; 77.44 ± 0.56; 600.21 ± 0.54) respectively. Based on the results obtained, the ethyl acetate extract of Litsea cubeba Lour. barks have antioxidant activity with a very strong category.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

BIOENERGY TRANSFORMATION OF PRESS MUD VIA ANAEROBIC DIGESTION USING IRON OXIDE NANOPARTICLES: AN ANALYSIS 利用氧化铁纳米颗粒厌氧消化对压浆进行生物能转化:分析

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1638011

S. Sundaranayagi, A. Sirajunnisa, S. Sarathkumar, Sk. Munimasthani

引用次数: 0

ANALYSIS OF DENSITY, BIODEGRADATION, AND MORPHOLOGY OF BIOPLASTIC COMPOSITES 生物塑料复合材料的密度、生物降解和形态分析

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1638313

D. Tanjung, R. S. Budi, M. Paramuji

引用次数: 0

A CAPILLARY GC-MS ANALYSIS OF RESIDUAL ETHANESULFONATES IN TENELIGLIPTIN 替尼格列汀中残留乙磺酸盐的毛细管气相色谱-质谱分析

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628311

M. Manivannan, P. Parthiban, P. Ilayaraja

引用次数: 0

QUANTIFICATION OF HAZARDOUS HIGH BOILING SOLVENTS IMPURITIES IN ANTI-DIABETIC DRUG LINAGLIPTIN BY NOVEL GC-ALS METHOD DEVELOPMENT AND VALIDATION 新型气相色谱法定量降糖药利格列汀中有害高沸溶剂杂质

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1638331

Sachin S. Garad, Dhananjay V. Mane

{"title":"QUANTIFICATION OF HAZARDOUS HIGH BOILING SOLVENTS IMPURITIES IN ANTI-DIABETIC DRUG LINAGLIPTIN BY NOVEL GC-ALS METHOD DEVELOPMENT AND VALIDATION","authors":"Sachin S. Garad, Dhananjay V. Mane","doi":"10.31788/rjc.2023.1638331","DOIUrl":"https://doi.org/10.31788/rjc.2023.1638331","url":null,"abstract":"A new precise and accurate GC-ALS method was developed and validated for quantitative determination of hazardous high boiling solvents impurities i.e. acetic acid and dimethyl sulphoxide in Linagliptin drug molecule using direct injection technique by GC-ALS with the help of Flame ionization detector (FID). The column used was Agilent J & W DB-FFAP, 30M X 0.530 mm X 1µm capillary column. The stationary phase of the column was nitro terephthalic acid-modified polyethylene glycol (PEG). The method was validated for specificity, precision, LOD, LOQ, accuracy, linearity, range, solution stability, and robustness. The detection limit and quantitation limit obtained for acetic acid was 83.3µg/g and 252.4 µg/g respectively. For Dimethyl sulphoxide detection limit and quantitation limit obtained were 83.7 µg/g and 253.7 µg/g respectively. The method was found to be linear in the range between 253.9 µg/g to 7616.9 µg/g for acetic acid and 253.5 µg/g to 7605.8 µg/g for dimethyl sulphoxide. The average recoveries obtained were 85.20% and 89.69% at LOQ level for acetic acid and dimethyl sulphoxide respectively, and for 150% level recovery were 94.26% and 100.43% for acetic acid and dimethyl sulphoxide respectively. The developed method was found to be robust, specificity was also demonstrated, and standard and the spiked solution was stable for up 20 Hrs. Thus, the method is used for routine analysis of their intended use. For quantification of Acetic acid and Dimethyl sulphoxide in Linagliptin, no pharmacopeial method is available so developed this simple method for laboratory use.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69412418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DETERMINATION OF SHELF LIFE OF AN AYURVEDIC FORMULATION KAISHORA GUGGULU USING RP-HPLC ANALYSIS OF CHEMICAL MARKERS 化学标记物反相高效液相色谱法测定阿育吠陀中药制剂枇杷膏的保质期

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1638336

Syeda Alisha Md Isha Ali, Niharika Gaddam, K. Bhat, B. Muddukrishna, Murlidhar Ballal, Sandeep G. Datarkar, S. G. Vasantharaju

引用次数: 0