MICROWAVE-ASSISTED FUNCTIONALIZATION OF INDAZOLES: AN OVERVIEW

Abstract

Indazole-based heterocyclic compounds possessing significant medicinal properties form the basis of developing several pharmaceuticals. Microwave-assisted organic synthesis is one of the most effective and promising techniques from the perspective of green chemistry, as it increases reaction rates and yields while decreasing wasteful byproducts. Functionalization of indazole derivatives under microwave irradiation is achieving tremendous interest in recent times. Various cross-coupling reactions are generally utilized during the microwave-assisted functionalization of indazoles. This review article chronologically describes different types of functionalization of indazoles assisted by microwave irradiation with up-to-date literature coverage.