Rasayan Journal of Chemistry最新文献

PHOTOCATALYTIC DEGRADATION OF RHODAMINE B UNDER UV USING DOUBLE-LAYER ZnO: Fe THIN FILM 双层ZnO: Fe薄膜在紫外光下光催化降解罗丹明B

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1617061

H. Sutanto, I. Alkian, Ulfa Hasanah, E. Hidayanto, I. Marhaendrajaya, Priyono

引用次数: 0

SYNTHESIS OF SILVER NANOPARTICLES USING ETHANOLIC EXTRACT OF Nelumbo nucifera Gaertn. LEAF AND ITS CYTOTOXIC ACTIVITY AGAINST T47D AND 4T1 CELL LINES 荷叶莲乙醇提取物合成纳米银的研究。叶片及其对t47d和4t1细胞系的细胞毒活性

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618000

K. Fitri, M. Andry, T. N. Khairani, H. S. Winata, A. Violenta, N. Lubis, M. F. Lubis

{"title":"SYNTHESIS OF SILVER NANOPARTICLES USING ETHANOLIC EXTRACT OF Nelumbo nucifera Gaertn. LEAF AND ITS CYTOTOXIC ACTIVITY AGAINST T47D AND 4T1 CELL LINES","authors":"K. Fitri, M. Andry, T. N. Khairani, H. S. Winata, A. Violenta, N. Lubis, M. F. Lubis","doi":"10.31788/rjc.2023.1618000","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618000","url":null,"abstract":"The cytotoxic activitiy of silver nanoparticles bio-functionalized by Nelumbo nucifera leaf extracts were examined in the current work. The nanoparticle (AgNPs) was characterized by scanning electron microscopy, UV–visible spectroscopy, and a particle size analyzer. Cytotoxic activity of silver nanoparticles against T47D and 4T1 cells using the MTT method using concentrations of 100 µg/mL, 50 µg/mL, and 25 µg/mL. For comparison, doxorubicin was used at the same dose. The size of the spherical nanoparticle was 66.4±0.93 nm and the polydispersity index was 0.23±0.05. Silver nanoparticles have anti-cancer properties against T47D and 4T1 cell lines based on inhibitory concentration. The inhibitory concentration (IC50) of AgNPs on T47D and 4T1 cells were obtained at 12.10±0.08 𝜇g/mL and 98.77±1.27 𝜇g/mL, respectively. Meanwhile, the IC50 values of doxorubicin in T47D and 4T1 cells were 4.45±0.03 𝜇g/mL and 36.77±1.15 𝜇g/mL, respectively. Overall, the results revealed that the green-synthetized silver nanoparticle had cytotoxic effects on breast cancer cells in comparison to doxorubicin.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69409800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

GREEN ENZYMES FROM PLANTS AND MICROBIAL SOURCES USED IN INDUSTRIES: AN OVERVIEW 植物和微生物来源的绿色酶在工业中的应用:概述

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1616846

Bhuvan Uthaiah Muruvanda, Akash Shanmugasundaram Prakash, K. Kalapriya, K. Sampath

引用次数: 0

DETERMINATION OF TOTAL PHYTOCHEMICAL COMPOUNDS FROM ETHANOL EXTRACT NANGKA (Artocarpus heterophyllus Lam.) LEAVES AND ANTIOXIDANT ACTIVITY FROM NORTH SUMATERA, INDONESIA 南卡乙醇提取物中总植物化学成分的测定印度尼西亚北苏门答腊叶及其抗氧化活性

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618113

Suharni P. Sinaga, R. Situmorang, N. Singarimbun, W. Lestari, K. Gurning

{"title":"DETERMINATION OF TOTAL PHYTOCHEMICAL COMPOUNDS FROM ETHANOL EXTRACT NANGKA (Artocarpus heterophyllus Lam.) LEAVES AND ANTIOXIDANT ACTIVITY FROM NORTH SUMATERA, INDONESIA","authors":"Suharni P. Sinaga, R. Situmorang, N. Singarimbun, W. Lestari, K. Gurning","doi":"10.31788/rjc.2023.1618113","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618113","url":null,"abstract":"Nangka (Artocarpus heterophyllus Lam.) has various nutritional contents and abundant bioactive compounds. Potential bioactive compounds including phenolic and flavonoid categorized as antioxidants. This study aimed to determine the levels of phenolics and flavonoids and to test their potential activity as antioxidants from the ethanol extract of nangka leaves. The extraction process used ethanol by maceration method, colorimetric determination of phenolic, flavonoid, and tannins content, and determination of antioxidant activity by 2,2-dipicryl -1-hydrazil (DPPH) method using UV-Vis spectrophotometry. Determination of phenolic content was measured at a maximum wavelength of 765 nm with gallic acid as the standard, flavonoid content was measured at a maximum wavelength of 431 nm with quercetin as standard, tannins content was measured at a maximum wavelength of 745 nm with tannic acid as standard and the determination of antioxidant activity at a maximum wavelength of 517 nm with positive control of vitamin C. The results showed that the ethanolic extract of nangka leaves has phenolic content with a total phenolic content of 27.654±0.054 mg GAE/g d.w ethanolic, flavonoid content of 2.978 ±0.192 mg QE/g d.w ethanolic, tannins content 0.46 ± 0.017 mg TAE/g d.w ethanolic extract and antioxidant activity (IC50) 25.561±0.055 ppm which categorized as a very strong antioxidant","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MICROWAVE FACILITATED THE SYNTHESIS OF ISOPROPYL MYRISTATE AND PALMITATE USING HETEROGENEOUS CATALYST 微波催化异相催化合成肉豆蔻酸异丙酯和棕榈酸酯

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618078

J. Tarigan, D. Barus, G. Brahmana, D. A. Hulu, W.S. Sembiring, S. Perangin-angin, E. K. Sitepu

引用次数: 1

STUDY OF MOLECULAR INTERACTIONS OF SUBSTITUTED 2-OXO-2-H-CHROMENE-3-CARBOHYDRAZIDE DERIVATIVES IN BINARY SOLVENTS USING ULTRASONIC INTERFEROMETER 用超声干涉仪研究取代的2-氧-2- h -铬-3-碳肼衍生物在二元溶剂中的分子相互作用

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618170

Pandurang Choudhari, P. V. Raut

引用次数: 0

IN VITRO ANTI-PROLIFERATIVE ACTIVITY OF NOVEL ANALOGUES OF(E)-2-BENZYLIDENE-N-(3-(3-OXO-2,3- DIHYDRO-4H-BENZO[B][1,4]OXAZIN-4-YL)PROPYL) HYDRAZINE-1-CARBOTHIOAMIDE 新型(e)-2-苄基- n -(3-(3-氧-2,3-二氢-4- h -苯并[b][1,4]恶嗪-4-基)丙基)肼-1-碳硫酰胺类似物的体外抗增殖活性

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628154

Palla Sai Lakshmi, P. Shankaraiah

引用次数: 0

APPLICATION OF SQUARE WAVE POTENTIAL REGIME TO ELECTRO REDUCTION OF CO2 IN ETHANOLAMINE INTO ETHYL CARBAMATE BY PALLADIUM ELECTRODE 方波电位在钯电极电还原乙醇胺中co2为氨基甲酸乙酯中的应用

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628290

A.K. Alkhawaldeh, A. Al-Dhuraibi

{"title":"APPLICATION OF SQUARE WAVE POTENTIAL REGIME TO ELECTRO REDUCTION OF CO2 IN ETHANOLAMINE INTO ETHYL CARBAMATE BY PALLADIUM ELECTRODE","authors":"A.K. Alkhawaldeh, A. Al-Dhuraibi","doi":"10.31788/rjc.2023.1628290","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628290","url":null,"abstract":"Electrochemical reduction of the CO2 present in 0.1 M Ethanolamine (EA) aqueous solution at Palladium metal electrodes for the synthesis of ethyl carbamate (CH3CH2OC(O)NH2) is investigated. The application square wave potential regime of the carbon dioxide in (EA) to be reduced to an organic product. In addition to identifying optimal conditions for CO2 electrocatalysis reduction by the square wave potential regime, the potential value was between - 1.0 to 0.4 V with 1.4 V amplitude, the time of reaction was 4 hours and the frequency was 100 Hz. We have carried out reactions at various pH levels and different voltages in an alkaline environment to ensure optimal conditions for the production of ethyl carbamate. The palladium catalysts electrode has demonstrated high CO2 electro-reduction activity to the organic compound. The organic product was analyzed by cyclic voltammetry, NMR, UV spectrometry, FT-IR spectroscopy, TGA, and MS. The results suggest the reduction of CO2-saturated in 0.1 M ethanolamine to ethyl carbamate, C2H5OCONH2. The Faradaic Efficiency and current density of electro-convert CO2-saturated in ethanolamine to ethyl carbamate are 93% and 71 mA cm−2, respectively","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EVALUATION OF CORROSION PROTECTION CAPACITY OF DOPED PPY FILM FOR STAINLESS STEEL IN AN ACIDIC MEDIUM 酸性介质中掺杂ppy膜对不锈钢的防腐性能评价

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628208

Monika, G. Rani, Naveen Kumar, R. Ahlawat

{"title":"EVALUATION OF CORROSION PROTECTION CAPACITY OF DOPED PPY FILM FOR STAINLESS STEEL IN AN ACIDIC MEDIUM","authors":"Monika, G. Rani, Naveen Kumar, R. Ahlawat","doi":"10.31788/rjc.2023.1628208","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628208","url":null,"abstract":"Advanced corrosion protection methods include covering stainless steel surfaces with conductive polymer-based coatings. Polypyrrole and polypyrrole composites of tungstate of different concentrations were deposited on stainless steel-304 using cyclic voltammetry and their elemental analysis was verified by EDX analysis. EIS and potentiodynamic polarization analysis show that the corrosion protection efficiency (CPE) of polypyrrole composites is higher than polypyrrole coating. The reduction in corrosion rate due to the inhibitory action of tungstate through the physical barrier and anodic protection mechanism was validated by greater Rct and lower Icorr values of polypyrrole composites. In the composites, with increasing the concentration of tungstate in polypyrrole from 5% to 15%, CPE also increases, as polypyrrole composites are more able to shift the corrosion potential of stainless steels towards the passive zone and form a new nonporous passive oxide film on the surface. With a 15% concentration coating, the highest CPE of 93% and the lowest corrosion rate of 130 mmpy were obtained, indicating that the entire stainless steel active surface area is completely absorbed and that no active sites exit for adsorption at this concentration. The synthesized polypyrrole composites with a 15% concentration offer excellent corrosion protection prospects.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

STABILITY INDICATING ISOCRATIC RP-HPLC AND SECOND DERIVATIVE UV SPECTROSCOPIC METHODS FOR SIMULTANEOUS DETERMINATION OF REMOGLIFLOZIN ETABONATE AND VILDAGLIPTIN HYDROCHLORIDE 稳定性表明等密度反相高效液相色谱法和二阶导数紫外光谱法同时测定盐酸维格列汀和雷莫列净

Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628212

J. Panchal, B. Dhaduk, J. Dhalani

{"title":"STABILITY INDICATING ISOCRATIC RP-HPLC AND SECOND DERIVATIVE UV SPECTROSCOPIC METHODS FOR SIMULTANEOUS DETERMINATION OF REMOGLIFLOZIN ETABONATE AND VILDAGLIPTIN HYDROCHLORIDE","authors":"J. Panchal, B. Dhaduk, J. Dhalani","doi":"10.31788/rjc.2023.1628212","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628212","url":null,"abstract":"Remogliflozin and Vildagliptin are the latest drug combination in order to treat type 2 diabetes. The present work describes a comparative study of 2nd-ordered derivative UV and isocratic stability indicating RP-HPLC methods for simultaneous determination of Remogliflozin and Vildagliptin in the drug and its formulation. The HPLC method was established with a C18 column and the mobile phase with Buffer (pH-6.50): Acetonitrile: Methanol ratio of 55:44:1, at 1.2 ml/min flow and wavelength of 210 nm. The UV spectrophotometric method works on spectrophotometry with 2nd order derivative spectra(2D) using a zero-line cross method. The absorbance determination was performed at 246.0 nm for REM and at 219 .6 nm for VIL. The methods were validated for Linearity, Precision, Recovery, Robustness, and Forced degradation as per ICH-Q2(R1). The linear range was established in the range of 4-80 ppm for REM and 2-40 ppm for VIL for the UV method and 2-200 ppm for REM and 1-100 ppm for VIL for the HPLC method with regression coefficient ≥0.990. The accuracy was 99.37% & 99.62% for UV and 100.98 & 100.65 for the HPLC method for REM and VIL respectively. The proposed methods have been effectively used for the quantification of REM and VIL in API mixture and formulation dosage forms. Both methods are economical, fast, simple, and accurate which can be easily adopted for laboratory use.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0