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GREEN ENZYMES FROM PLANTS AND MICROBIAL SOURCES USED IN INDUSTRIES: AN OVERVIEW 植物和微生物来源的绿色酶在工业中的应用:概述
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1616846
Bhuvan Uthaiah Muruvanda, Akash Shanmugasundaram Prakash, K. Kalapriya, K. Sampath
{"title":"GREEN ENZYMES FROM PLANTS AND MICROBIAL SOURCES USED IN INDUSTRIES: AN OVERVIEW","authors":"Bhuvan Uthaiah Muruvanda, Akash Shanmugasundaram Prakash, K. Kalapriya, K. Sampath","doi":"10.31788/rjc.2023.1616846","DOIUrl":"https://doi.org/10.31788/rjc.2023.1616846","url":null,"abstract":"Green chemistry, an emerging field of science, focuses on the prevention of waste and the use of hazardous substances. It also emphasizes the elimination or reduction of the use of harmful elements in various stages of the manufacturing process or a product development setting. The unpredictable climatic changes and the environmental hazards produced by the industries made the researcher’s attention in this arena. At present, industries make an effort to produce their products greener. As a consequence, several biotechnological and biological applications join hands with green chemistry, making the manufacturing process not only greener but also economical. Enzymes are the result of the combination of green chemistry and biotechnology. In the current scenario, there is a need for new versatile enzymes to develop sustainable and economically competitive production processes. The present article reviews the types of enzymes obtained from plants and microorganisms used in different industries and their vital role in the conservation of an eco-friendly environment.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
APPLICATION OF SQUARE WAVE POTENTIAL REGIME TO ELECTRO REDUCTION OF CO2 IN ETHANOLAMINE INTO ETHYL CARBAMATE BY PALLADIUM ELECTRODE 方波电位在钯电极电还原乙醇胺中co2为氨基甲酸乙酯中的应用
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628290
A.K. Alkhawaldeh, A. Al-Dhuraibi
{"title":"APPLICATION OF SQUARE WAVE POTENTIAL REGIME TO ELECTRO REDUCTION OF CO2 IN ETHANOLAMINE INTO ETHYL CARBAMATE BY PALLADIUM ELECTRODE","authors":"A.K. Alkhawaldeh, A. Al-Dhuraibi","doi":"10.31788/rjc.2023.1628290","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628290","url":null,"abstract":"Electrochemical reduction of the CO2 present in 0.1 M Ethanolamine (EA) aqueous solution at Palladium metal electrodes for the synthesis of ethyl carbamate (CH3CH2OC(O)NH2) is investigated. The application square wave potential regime of the carbon dioxide in (EA) to be reduced to an organic product. In addition to identifying optimal conditions for CO2 electrocatalysis reduction by the square wave potential regime, the potential value was between - 1.0 to 0.4 V with 1.4 V amplitude, the time of reaction was 4 hours and the frequency was 100 Hz. We have carried out reactions at various pH levels and different voltages in an alkaline environment to ensure optimal conditions for the production of ethyl carbamate. The palladium catalysts electrode has demonstrated high CO2 electro-reduction activity to the organic compound. The organic product was analyzed by cyclic voltammetry, NMR, UV spectrometry, FT-IR spectroscopy, TGA, and MS. The results suggest the reduction of CO2-saturated in 0.1 M ethanolamine to ethyl carbamate, C2H5OCONH2. The Faradaic Efficiency and current density of electro-convert CO2-saturated in ethanolamine to ethyl carbamate are 93% and 71 mA cm−2, respectively","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EVALUATION OF CORROSION PROTECTION CAPACITY OF DOPED PPY FILM FOR STAINLESS STEEL IN AN ACIDIC MEDIUM 酸性介质中掺杂ppy膜对不锈钢的防腐性能评价
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628208
Monika, G. Rani, Naveen Kumar, R. Ahlawat
{"title":"EVALUATION OF CORROSION PROTECTION CAPACITY OF DOPED PPY FILM FOR STAINLESS STEEL IN AN ACIDIC MEDIUM","authors":"Monika, G. Rani, Naveen Kumar, R. Ahlawat","doi":"10.31788/rjc.2023.1628208","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628208","url":null,"abstract":"Advanced corrosion protection methods include covering stainless steel surfaces with conductive polymer-based coatings. Polypyrrole and polypyrrole composites of tungstate of different concentrations were deposited on stainless steel-304 using cyclic voltammetry and their elemental analysis was verified by EDX analysis. EIS and potentiodynamic polarization analysis show that the corrosion protection efficiency (CPE) of polypyrrole composites is higher than polypyrrole coating. The reduction in corrosion rate due to the inhibitory action of tungstate through the physical barrier and anodic protection mechanism was validated by greater Rct and lower Icorr values of polypyrrole composites. In the composites, with increasing the concentration of tungstate in polypyrrole from 5% to 15%, CPE also increases, as polypyrrole composites are more able to shift the corrosion potential of stainless steels towards the passive zone and form a new nonporous passive oxide film on the surface. With a 15% concentration coating, the highest CPE of 93% and the lowest corrosion rate of 130 mmpy were obtained, indicating that the entire stainless steel active surface area is completely absorbed and that no active sites exit for adsorption at this concentration. The synthesized polypyrrole composites with a 15% concentration offer excellent corrosion protection prospects.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SYNTHESIS AND CHARACTERIZATION OF BENZOXAZINE: URETHANE COPOLYMER FROM VANILLIN WITH ADAMANTANE SIDE CHAIN AND ITS ANTICORROSIVE COATING ON MILD STEEL 含金刚烷侧链香兰素-氨基甲酸乙酯共聚物的合成与表征及其在低碳钢上的防腐涂层
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628362
K. Jayanthi, M. Sivaraju
{"title":"SYNTHESIS AND CHARACTERIZATION OF BENZOXAZINE: URETHANE COPOLYMER FROM VANILLIN WITH ADAMANTANE SIDE CHAIN AND ITS ANTICORROSIVE COATING ON MILD STEEL","authors":"K. Jayanthi, M. Sivaraju","doi":"10.31788/rjc.2023.1628362","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628362","url":null,"abstract":"Corrosion is a significant issue with metallic materials, notably in steel due to its extensive use in a variety of industries. Benzoxazine polymers have been used to produce anti-corrosive compounds that have a remarkable ability to limit corrosion. In the same ink line, we have explored a new approach with a very hydrophobic benzoxazine monomer which is co-polymerized with urethane, and its characterization was studied with IR, UV, and NMR techniques. The corrosion resistance of the same is investigated using Tafel polarization and EIS experiment methodologies. The DFT and MEP studies explain the reactivity towards the anti-corrosive properties of the monomer.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COORDINATION BEHAVIOUR AND COMPUTATIONAL STUDIES OF 3-FORMYL CHROMONE N(4)-METHYL-N(4)- PHENYLTHIOSEMICARBAZONE AND ITS TRANSITION METAL COMPLEXES 3-甲酰基色素n(4)-甲基- n(4)-苯基硫代氨基脲及其过渡金属配合物的配位行为和计算研究
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1638352
K. Sangeetha, K. K. Aravindakshan
{"title":"COORDINATION BEHAVIOUR AND COMPUTATIONAL STUDIES OF 3-FORMYL CHROMONE N(4)-METHYL-N(4)- PHENYLTHIOSEMICARBAZONE AND ITS TRANSITION METAL COMPLEXES","authors":"K. Sangeetha, K. K. Aravindakshan","doi":"10.31788/rjc.2023.1638352","DOIUrl":"https://doi.org/10.31788/rjc.2023.1638352","url":null,"abstract":"This article reports on the 3-formylchromone N(4)-substituted thiosemicarbazone’s coordination behavior towards transition metal ions. CHNS analysis, magnetic moment, thermal analysis, IR, UV, NMR, and EPR spectroscopy were used to characterize the compounds. Moreover, DFT, insilico ADME, and docking studies of the ligand were done. Based on the spectral results, copper, cobalt, and nickel complexes had square planar geometry. Conversely, the manganese complex has octahedral geometry. The Gaussian 09 program is utilized for DFT studies. The GLIDE program was used for docking calculations. As receptor molecules, histone deacetylase, ribonucleotide reductase, and DNA methyltransferase were chosen. The SwissADME tool was used to evaluate the pharmacokinetics of the ligand. Based on Lipinski's rules, the estimation of insilico ADMET discovered that ligands procure significant drug-likeness characteristics. Its ability to block histone deacetylase 8 (PDB ID 1T69) protein is shown by docking calculations, and its proper action can be further confirmed in wet lab tests.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69412575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PHOTOCATALYTIC DEGRADATION OF RHODAMINE B UNDER UV USING DOUBLE-LAYER ZnO: Fe THIN FILM 双层ZnO: Fe薄膜在紫外光下光催化降解罗丹明B
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1617061
H. Sutanto, I. Alkian, Ulfa Hasanah, E. Hidayanto, I. Marhaendrajaya, Priyono
{"title":"PHOTOCATALYTIC DEGRADATION OF RHODAMINE B UNDER UV USING DOUBLE-LAYER ZnO: Fe THIN FILM","authors":"H. Sutanto, I. Alkian, Ulfa Hasanah, E. Hidayanto, I. Marhaendrajaya, Priyono","doi":"10.31788/rjc.2023.1617061","DOIUrl":"https://doi.org/10.31788/rjc.2023.1617061","url":null,"abstract":"Waste dyes are a major source of water pollution, which is a critical environmental issue. The purpose of this study is to synthesize double-layer ZnO: Fe 5-20% thin films and investigate the degradation of rhodamine B in these films. The creation of the ZnO phase with the wurtzite hexagonal structure may be seen in the thin film X-ray diffraction pattern. Only marginally lessened energy bandgap (3.11-3.09 eV), optical transmission spectra, and lattice strain was seen after Fe was added to ZnO thin films. With increasing Fe concentration, it was found that the hydrophilicity and photocatalytic characteristics of ZnO thin films considerably decreased, as shown by the contact angle going from 51.4 to 70.71 and the decomposition efficiency going from 61.46% to 50.35%. The double-layer ZnO layer's optical characteristics diminish as the Fe concentration rises.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69409791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DETERMINATION OF TOTAL PHYTOCHEMICAL COMPOUNDS FROM ETHANOL EXTRACT NANGKA (Artocarpus heterophyllus Lam.) LEAVES AND ANTIOXIDANT ACTIVITY FROM NORTH SUMATERA, INDONESIA 南卡乙醇提取物中总植物化学成分的测定印度尼西亚北苏门答腊叶及其抗氧化活性
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618113
Suharni P. Sinaga, R. Situmorang, N. Singarimbun, W. Lestari, K. Gurning
{"title":"DETERMINATION OF TOTAL PHYTOCHEMICAL COMPOUNDS FROM ETHANOL EXTRACT NANGKA (Artocarpus heterophyllus Lam.) LEAVES AND ANTIOXIDANT ACTIVITY FROM NORTH SUMATERA, INDONESIA","authors":"Suharni P. Sinaga, R. Situmorang, N. Singarimbun, W. Lestari, K. Gurning","doi":"10.31788/rjc.2023.1618113","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618113","url":null,"abstract":"Nangka (Artocarpus heterophyllus Lam.) has various nutritional contents and abundant bioactive compounds. Potential bioactive compounds including phenolic and flavonoid categorized as antioxidants. This study aimed to determine the levels of phenolics and flavonoids and to test their potential activity as antioxidants from the ethanol extract of nangka leaves. The extraction process used ethanol by maceration method, colorimetric determination of phenolic, flavonoid, and tannins content, and determination of antioxidant activity by 2,2-dipicryl -1-hydrazil (DPPH) method using UV-Vis spectrophotometry. Determination of phenolic content was measured at a maximum wavelength of 765 nm with gallic acid as the standard, flavonoid content was measured at a maximum wavelength of 431 nm with quercetin as standard, tannins content was measured at a maximum wavelength of 745 nm with tannic acid as standard and the determination of antioxidant activity at a maximum wavelength of 517 nm with positive control of vitamin C. The results showed that the ethanolic extract of nangka leaves has phenolic content with a total phenolic content of 27.654±0.054 mg GAE/g d.w ethanolic, flavonoid content of 2.978 ±0.192 mg QE/g d.w ethanolic, tannins content 0.46 ± 0.017 mg TAE/g d.w ethanolic extract and antioxidant activity (IC50) 25.561±0.055 ppm which categorized as a very strong antioxidant","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MICROWAVE FACILITATED THE SYNTHESIS OF ISOPROPYL MYRISTATE AND PALMITATE USING HETEROGENEOUS CATALYST 微波催化异相催化合成肉豆蔻酸异丙酯和棕榈酸酯
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618078
J. Tarigan, D. Barus, G. Brahmana, D. A. Hulu, W.S. Sembiring, S. Perangin-angin, E. K. Sitepu
{"title":"MICROWAVE FACILITATED THE SYNTHESIS OF ISOPROPYL MYRISTATE AND PALMITATE USING HETEROGENEOUS CATALYST","authors":"J. Tarigan, D. Barus, G. Brahmana, D. A. Hulu, W.S. Sembiring, S. Perangin-angin, E. K. Sitepu","doi":"10.31788/rjc.2023.1618078","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618078","url":null,"abstract":"In the present research, a microwave-intensified esterification reaction of myristic acid and palmitic acid with isopropyl alcohol (IPA) to produce an emollient ester using Amberlyst46 as a catalyst was studied. The effect of the ratio of molar fatty acid to alcohol, catalyst weight, reaction time, and microwave power on isopropyl myristate (IPM) and isopropyl palmitate (IPP) conversion and yield were investigated systematically. The results showed that catalyst weight and microwave power significantly affect the conversion and yield of IPM and IPP, respectively. The maximum conversion and yield of IPM were achieved under microwave irradiation power of 100% and catalyst weight of 15 wt.% while only 50% microwave power was required to achieve maximum conversion and yield of IPP using 18 wt.% of catalyst weight. These findings show that microwave-facilitated esterification reaction is a promising alternative method to produce emollient ester as the maximum conversion could achieve in a short reaction time.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
STUDY OF MOLECULAR INTERACTIONS OF SUBSTITUTED 2-OXO-2-H-CHROMENE-3-CARBOHYDRAZIDE DERIVATIVES IN BINARY SOLVENTS USING ULTRASONIC INTERFEROMETER 用超声干涉仪研究取代的2-氧-2- h -铬-3-碳肼衍生物在二元溶剂中的分子相互作用
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618170
Pandurang Choudhari, P. V. Raut
{"title":"STUDY OF MOLECULAR INTERACTIONS OF SUBSTITUTED 2-OXO-2-H-CHROMENE-3-CARBOHYDRAZIDE DERIVATIVES IN BINARY SOLVENTS USING ULTRASONIC INTERFEROMETER","authors":"Pandurang Choudhari, P. V. Raut","doi":"10.31788/rjc.2023.1618170","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618170","url":null,"abstract":"At 32°C, the apparent molal volume (v), apparent molal compressibility (k), relative association (RA), and solvation number (Sn) of substituted 2-oxo-2-H-chromene-3-carbohydrazide derivatives in 60% DMF-water were measured. The data is used to determine the interaction that is taking place in the solution. The ultrasonic technique is used to determine the interaction of a solute and a solvent. The variation of factors in binary mixtures with different concentrations indicates a significant interaction between solute and solvent molecules, associative molecular interaction, and ion-solvent interaction.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IN VITRO ANTI-PROLIFERATIVE ACTIVITY OF NOVEL ANALOGUES OF(E)-2-BENZYLIDENE-N-(3-(3-OXO-2,3- DIHYDRO-4H-BENZO[B][1,4]OXAZIN-4-YL)PROPYL) HYDRAZINE-1-CARBOTHIOAMIDE 新型(e)-2-苄基- n -(3-(3-氧-2,3-二氢-4- h -苯并[b][1,4]恶嗪-4-基)丙基)肼-1-碳硫酰胺类似物的体外抗增殖活性
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628154
Palla Sai Lakshmi, P. Shankaraiah
{"title":"IN VITRO ANTI-PROLIFERATIVE ACTIVITY OF NOVEL ANALOGUES OF(E)-2-BENZYLIDENE-N-(3-(3-OXO-2,3- DIHYDRO-4H-BENZO[B][1,4]OXAZIN-4-YL)PROPYL) HYDRAZINE-1-CARBOTHIOAMIDE","authors":"Palla Sai Lakshmi, P. Shankaraiah","doi":"10.31788/rjc.2023.1628154","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628154","url":null,"abstract":"A novel analog of substituted-(E)-2-benzylidene-N-(3-(3-oxo-2,3-dihydro-4H-benzo[b] [1,4] oxazin-4-yl)propyl) hydrazine-1-carbothioamides (9a-j) appeared to be assess being anti-proliferative activity in vitro environment some of the newly derived derivatives have shown sufficiently great to modest suppression in the number of cells in cancer among GrowthInhibition50 was (0.180-4.20 µM). Compounds 9a, 9b, 9d, 9g, 9i, and 9j showed promising acts contrarily 4 human being tumor cell lines. Out of 9a and 9g displayed heartening cancer act in opposition to IMR-32 (Human being neuroblastoma cells) at 0.23 M and MIAPACA(human pancreatic carcinoma cells) at 0.18 M respectively. Notably, compound 9g showed significant activity at 0.18 M against the MIAPACA cell line respectively.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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