Rasayan Journal of Chemistry最新文献

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ADSORPTION CAPACITY, KINETICS, AND APPLICATION OF MOLECULARLY IMPRINTED POLYMERS DI-(2-ETHYLHEXYL) PHTHALATE AS ADSORBENTS IN SOLID-PHASE EXTRACTION METHOD 分子印迹聚合物邻苯二甲酸二(2-乙基己基)酯在固相萃取法中的吸附能力、动力学和应用
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1636816
None S. Fauziah, N.H. Soekamto, None P. Taba, A. M. Gafur, None A. Sapar
{"title":"ADSORPTION CAPACITY, KINETICS, AND APPLICATION OF MOLECULARLY IMPRINTED POLYMERS DI-(2-ETHYLHEXYL) PHTHALATE AS ADSORBENTS IN SOLID-PHASE EXTRACTION METHOD","authors":"None S. Fauziah, N.H. Soekamto, None P. Taba, A. M. Gafur, None A. Sapar","doi":"10.31788/rjc.2023.1636816","DOIUrl":"https://doi.org/10.31788/rjc.2023.1636816","url":null,"abstract":"The purpose of this research is to synthesize, characterize, optimize, and apply MIP as an adsorbent material for solid phase extraction (SPE). The synthesis method used is precipitation polymerization. MAA as a monomer was combined with EGDMA as a crosslinker and used DEHP as imprinting molecules. Structural characterization of MIP using SEM","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135596717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE EFFECT OF pH ON THE SYNTHESIS AND CHARACTERIZATION OF HYDROXYAPATITEPOLYETHYLENE GLYCOL COMPOSITES BY IN-SITU PROCESS 研究了pH对原位合成羟基磷灰石聚乙二醇复合材料的影响
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1638319
Novesar Jamarun, Zulia Rahma Putri, Upita Septiani, Yulizar Yusuf, Vivi Sisca, None Zilfa
{"title":"THE EFFECT OF pH ON THE SYNTHESIS AND CHARACTERIZATION OF HYDROXYAPATITEPOLYETHYLENE GLYCOL COMPOSITES BY IN-SITU PROCESS","authors":"Novesar Jamarun, Zulia Rahma Putri, Upita Septiani, Yulizar Yusuf, Vivi Sisca, None Zilfa","doi":"10.31788/rjc.2023.1638319","DOIUrl":"https://doi.org/10.31788/rjc.2023.1638319","url":null,"abstract":"Hydroxyapatite (HAp) has a structure and chemical composition similar to bone and teeth, so Hap is widely used in the biomedical field. However, Hap has the disadvantage of being brittle, so it needs to be composited with polyethylene glycol (PEG) using an in-situ method with the aim of improving the mechanical properties of Hap. X-Rays Diffraction (XRD) results show a diffraction pattern at an angle of 2θ which is in accordance with the Hap standard (ICSD #97849). Fourier-Transform infrared (FTIR) characterization showed the presence of Hap and PEG functional group vibrations. Characterization of Scanning Electron Microscopy-Energy Dispersive Spectroscopy (SEM-EDS) showed that the synthesis pH can be morphological and Hap ratio. Thermogravimetric Differential Analysis Thermal Analysis (TGA-DTA) analyzed that the HAP/PEG composites decreased in weight at temperatures >200°C due to the decomposition of organic compounds originating from PEG. The results of the Hap/PEG composite degradation behavior test showed that pH 10 was the optimum synthesis pH.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135596719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SYNTHETIC STUDY OF Pc-2, AN ACTIVE COMPOUND FROM INDONESIAN RED BETEL LEAF 印尼红槟榔叶活性化合物Pc-2的合成研究
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1617052
Ritmaleni, Dong-Hwi Kim
{"title":"SYNTHETIC STUDY OF Pc-2, AN ACTIVE COMPOUND FROM INDONESIAN RED BETEL LEAF","authors":"Ritmaleni, Dong-Hwi Kim","doi":"10.31788/rjc.2023.1617052","DOIUrl":"https://doi.org/10.31788/rjc.2023.1617052","url":null,"abstract":"PC-2 is one of the active compounds isolated from Indonesian red betel leaf. The structure of the compound is named 2-allyl-4-(1'-hydroxy-1'-(3\",4\",5\"-trimethoxyphenyl)propan-2'-yl)-3,5-dimethoxycyclohexa-3,5-dienone and included in the neolignan’s structure category. This compound was reported to have very good biological activity in giving antiproliferative effects on human breast (T47D) cells. From 2.12 g of its leaf methanolic extract, only 12.1 mg of Pc-2 was collected. This amount is too small to do more studies about its biological activities. The synthetic work should be applied to get a sufficient amount. This paper is aimed to explain the synthetic study and design of the Pc2 compound. The first approach is by involving the aldol reaction in the synthetic pathway through the disconnection approach. The result showed that this attempt did not work very well. The second approach is to design the new synthetic pathway by using the synthia Organic Retrosynthesis Software by Merck. This software gave a reasonable result to be tried. The result proposed the use of the Suzuki coupling reaction for the new synthetic pathway of Pc-2.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69409787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NOVEL SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF N-(5BROMO-2-(5-PHENYL1,3,4-OXADIAZOL-2-YL)NAPHTHA[2,1-B]FURAN-1- YL)ACETAMIDE AND N-(5-NITRO-2-(5-PHENYL-1,3,4- OXADIAZOL-2-YL)NAPHTHA[2,1-BFURAN-1-YL]ACETAMIDE AND THEIR DERIVATIVES n -(5-溴-2-(5-苯基1,3,4-恶二唑-2-基)萘[2,1- b]呋喃-1-基)乙酰胺和n -(5-硝基-2-(5-苯基-1,3,4-恶二唑-2-基)萘[2,1-呋喃-1-基]乙酰胺及其衍生物的新合成、表征和抗菌活性
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618088
K. M. Nagarsha, T. Sharanakumar, D. Ramesh, N. Kumar, M. N. Kumarswamy, D. Ramesh, K. P. Latha
{"title":"NOVEL SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF N-(5BROMO-2-(5-PHENYL1,3,4-OXADIAZOL-2-YL)NAPHTHA[2,1-B]FURAN-1- YL)ACETAMIDE AND N-(5-NITRO-2-(5-PHENYL-1,3,4- OXADIAZOL-2-YL)NAPHTHA[2,1-BFURAN-1-YL]ACETAMIDE AND THEIR DERIVATIVES","authors":"K. M. Nagarsha, T. Sharanakumar, D. Ramesh, N. Kumar, M. N. Kumarswamy, D. Ramesh, K. P. Latha","doi":"10.31788/rjc.2023.1618088","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618088","url":null,"abstract":"The novel derivatives of naphtho-furan such N-(5bromo-2-(5-phenyl-1,3,4-oxadiazol-2-yl)naphtha[2,1-b]furan-1- yl)acetamide (8), N-(5-bromo-2-(hydrazinecarbonyl)naphtha[2,1-b]furan-1-yl]acetamide (7), ethyl-1-acetamido-5- bromonaphtho[2,1-b]furan-2-carboxylate (6), N-(5-nitro-2-(5-phenyl-1,3,4-oxadiazol-2-yl)naphtha[2,1-bfuran-1- yl]acetamide (5),N-(2-(hydrazinecarbonyl)-5-nitronaphtho[2,1-b]furan-1-yl)acetamide (4), ethyl-1-acetamido-5- nitrpnaphtho[2,1-b]furan-2-carboxylate (3), are prepared by ethyl-1-acetamidonaphtho[2,1-b]furan-2-carboxyate and ethyl 1-aminonaphtho[2,1-b]furan-2-carboxylate. All newly synthesized compounds were confirmed by Mass, NMR, and FTIR spectroscopic techniques. Those compounds were used for antimicrobial activity it exhibits good antibacterial and anti-functional activity.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GREEN SYNTHESIS OF SILVER NANOPARTICLES FROM Scoparia dulcis L. PLANT EXTRACT AND ITS In-vitro ACETYLCHOLINESTERASE, ANTIOXIDANT ACTIVITY 绿色银纳米颗粒的合成及其体外乙酰胆碱酯酶、抗氧化活性研究
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618075
R. Mini, V. Prabhu, K. Poonkodi, K. Vimaladevi, K. Revathi
{"title":"GREEN SYNTHESIS OF SILVER NANOPARTICLES FROM Scoparia dulcis L. PLANT EXTRACT AND ITS In-vitro ACETYLCHOLINESTERASE, ANTIOXIDANT ACTIVITY","authors":"R. Mini, V. Prabhu, K. Poonkodi, K. Vimaladevi, K. Revathi","doi":"10.31788/rjc.2023.1618075","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618075","url":null,"abstract":"Silver oxide nanoparticles exhibit distinctive material and biotic properties that contain passionate research impact as vital applications in the pharmaceutical, biomedical, paper and textile industries. The goal of the current task is to synthesize AgNPs through a facile, low-cost, environmentally friendly route. In this method, we use the aqueous leaf extract of Scoparia dulcis Linn, found in the Western Ghats region, because the use of an aqueous medium is critical for reducing time and minimizing the possibility of side effects. The synthesized Ag nanoparticles were evaluated using UV-Visible, FTIR technique, scanning electron microscopy (SEM) with EADX, transmission electron microscopy (TEM), X-ray powder diffraction (XRD). Results confirmed that UV-visible spectroscopic analysis showed the absorbance peak at 460 nm, which implies the formation of silver nanoparticles. The FTIR spectrum aimed to such that biomolecules involved in wrapping and binding AgNPs synthesized by the plant extract. SEM and TEM are used to visualize the size and shape of nanoparticles. The XRD analysis revealed spherical structures with an average grain size of 21nm and a diameter range of 2 to 20nm. The EDAX study also exhibits the presence of 86.34 % Silver and 13.6 % Oxygen. Alzheimer's disease symptoms were controlled with a drug known as an acetylcholinesterase inhibitor. The in vitro acetylcholinesterase inhibitory activity of the AgNPs from Scoparia dulcis plant extract was evaluated using an Ellman's test with an IC50 value of 149µg/ml. The generated nanoparticles significantly inhibit AChE. The SD-AgNPs were examined for antioxidant activity via the DPPH and ABTS assays having IC50 values of 73.29µg/ml and 55.29µg/ml, respectively","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SYNTHESIS AND CHARACTERIZATION OF BARIUM MHEXAFERRITE BaFe12-2xCoxZnxO19 (0 ≤ X ≤ 1) PREPARED FROM CO-PRECIPITATION 共沉淀法制备钡铁氧体BaFe12-2xCoxZnxO19(0≤X≤1)的合成与表征
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1626810
Susilawati, D. Pangga, M. Zainuri, A. Doyan, S. Prayogi, M. R. Bilad
{"title":"SYNTHESIS AND CHARACTERIZATION OF BARIUM MHEXAFERRITE BaFe12-2xCoxZnxO19 (0 ≤ X ≤ 1) PREPARED FROM CO-PRECIPITATION","authors":"Susilawati, D. Pangga, M. Zainuri, A. Doyan, S. Prayogi, M. R. Bilad","doi":"10.31788/rjc.2023.1626810","DOIUrl":"https://doi.org/10.31788/rjc.2023.1626810","url":null,"abstract":"Barium hexaferrite (BaFe12O19) has attracted research attention due to its diverse applications. This study reports the synthesis of barium M-hexaferrite (BaFe12-2xCoxZnxO19) powder using co-precipitation of BaCO3 and FeCl3.6H2O powder, Co and Zn powder as a dopant material on the variation of x = 0, 0.2, 0.4, 0.6, 0.8, and 1. Results show that co-precipitation is an effective method for the synthesis of nanomaterial barium M-hexaferrites (BaFe12-2xCoxZnxO19) containing >89% of Fe elements and an average particle size of 50 nm. The DTA/TGA analyses show phase transformation at T ≤ 285°C and T = 750-840°C. The results of refinement using the Rietveld method show that the barium M-hexaferrite phase begins to form at low temperatures, with the best yield at x = 0.4. At high temperatures T > 740°C, it tends to form single-phase α-Fe2O3 (hematite). Substitution ion dopant Co/Zn only slightly changes the lattice parameters of the hexagonal basic crystal structure","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
DESIGN, SYNTHESIS, AND PHARMACOLOGICAL EVALUATION OF NOVEL BIS-INTERCALATORS AS POSSIBLE ANTICANCER AGENTS 新型双插层剂的设计、合成和药理学评价
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618207
{"title":"DESIGN, SYNTHESIS, AND PHARMACOLOGICAL EVALUATION OF NOVEL BIS-INTERCALATORS AS POSSIBLE ANTICANCER AGENTS","authors":"","doi":"10.31788/rjc.2023.1618207","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618207","url":null,"abstract":"An attempt is made to design, synthesize and pharmacologically evaluate novel bis-intercalators as possible anticancer agents. According to a literature study on bis-intercalators, 4-substituted bis-benzamides are widely recognized for their medicinal uses and may be effective anticancer and antioxidant agents. Synthetic studies revealed that the yield of Chain linkers L1-L14, 4-substituted bis benzamides, and L-proline derivatives were in the 50-70% range. The 4-substituted bis benzamides compounds have been evaluated for anticancer and antioxidant activity studies. Among the 4-substituted bis benzamides compounds, Compound IIIc, IIIf, and IIIg have revealed promising anticancer and antioxidant activity. Compounds III7 and III12 have good cytotoxicity and antioxidant activity among L-proline derivatives. As a result, the current study emphasizes the significance of 4-substituted bis benzamides and L-proline derivatives with various heterocyclic moiety features responsible for cytotoxicity and antioxidant activity. It might be a starting point for further alterations to create new entities with therapeutically useful properties.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MICROENCAPSULATION OF FLAVONOIDS FROM GEDI LEAVES (Abelmoschus manihot L.) IN β-CYCLODEXTRIN USING COPRECIPITATION AND KNEADING METHODS 葛地叶黄酮的微胶囊化研究在β-环糊精中采用共沉淀法和揉制法
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1628287
H. Parbuntari, F. Azra, O. Suryani, M. Melati
{"title":"MICROENCAPSULATION OF FLAVONOIDS FROM GEDI LEAVES (Abelmoschus manihot L.) IN β-CYCLODEXTRIN USING COPRECIPITATION AND KNEADING METHODS","authors":"H. Parbuntari, F. Azra, O. Suryani, M. Melati","doi":"10.31788/rjc.2023.1628287","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628287","url":null,"abstract":"The protection of active compounds such as flavonoids as candidate drug compounds has been the focus of several studies in recent years. This is due to the different physicochemical properties of flavonoids. Furthermore, the function of these flavonoid compounds can be maximized from the initial process of separating them from the plant of origin known as extraction. This study compared the effectiveness and efficiency of using microwave extraction and maceration of Gedi leaves (Abelmoschus manihot L.). Then, the extract was encapsulated to protect the unstable flavonoids. There were two methods to encapsulate the extract in this study. They were the coprecipitation and kneading methods. The result shows that microwave extraction assisted has higher product in less solvent and was time-consuming. The coprecipitation also shows better performance in encapsulating the extract. The calculation of the efficiency of encapsulation was done for 3 different volumes of both methods. The addition of 1 mL extract by coprecipitation showed approximately 92.12%. It was also supported by the data of FTIR and UV VIS.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SYNTHESIS, MOLECULAR DOCKING, IN-SILICO ADMET SCREENING, STRUCTURAL SAFETY EVALUATION OF ABACAVIR SULFATE AND ITS NOVEL MODIFIED SUBSTANCE 硫酸阿巴卡韦及其新型修饰物的合成、分子对接、硅基筛选、结构安全性评价
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1638335
Mohit Ananda, Abhishek Ghosh, Hridhya Mohandas, Rudranil Karmakar, Belagala Nagesh, S. Jubie, Sanal Dev K. T., Jeyaprakash M. R.
{"title":"SYNTHESIS, MOLECULAR DOCKING, IN-SILICO ADMET SCREENING, STRUCTURAL SAFETY EVALUATION OF ABACAVIR SULFATE AND ITS NOVEL MODIFIED SUBSTANCE","authors":"Mohit Ananda, Abhishek Ghosh, Hridhya Mohandas, Rudranil Karmakar, Belagala Nagesh, S. Jubie, Sanal Dev K. T., Jeyaprakash M. R.","doi":"10.31788/rjc.2023.1638335","DOIUrl":"https://doi.org/10.31788/rjc.2023.1638335","url":null,"abstract":"Abacavir Sulfate is a nucleoside analog and reverse transcriptase inhibitor which is used in combination with Lamivudine and Zidovudine for the treatment of HIV and AIDS. Abacavir has higher toxicity levels and is least stable in heat. The specified temperature for the drug was proposed to be not more than 25°C. The present study focuses on the stability-related problem of the ABC. The new synthetic moiety will help to stabilize the drug, it can be used as a pro-drug formulation and can take the present scenario of the market which supplies any anti-retroviral drug. The aim of the current study is to synthesize a novel drug using Schiff base synthesis and perform its structural elucidation by different modes of Instrumental Analysis and perform in silico studies. From the above study, we can conclude that the novel moiety is safe to use as a drug and could be explored furthermore for its use.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69412454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PHYTOCHEMICAL ANALYSIS IN ROOTS AND TUBERS OF BOTSWANA MEDICINAL PLANTS- Solanum Aculeastrum dunal, Elephantorrhiza elephentina, Cadaba aphylla (Thunb) AND Adenia glauca 博茨瓦纳药用植物- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Rasayan Journal of Chemistry Pub Date : 2023-01-01 DOI: 10.31788/rjc.2023.1618097
A. Immaculate, J. Vimala, D. Takuwa
{"title":"PHYTOCHEMICAL ANALYSIS IN ROOTS AND TUBERS OF BOTSWANA MEDICINAL PLANTS- Solanum Aculeastrum dunal, Elephantorrhiza elephentina, Cadaba aphylla (Thunb) AND Adenia glauca","authors":"A. Immaculate, J. Vimala, D. Takuwa","doi":"10.31788/rjc.2023.1618097","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618097","url":null,"abstract":"Medicinal plants play an important role in our life. Worldwide modern drugs used in healthcare are derived from plants. Several Rhizomes and tubers are important for people due to their edible as well as medicinal properties. The Rhizome and tuberous plants namely Solanum aculeastrum dunal, Elephantorrhiza elephentina, Cadaba aphylla (Thunb), and Adenia glauca which are indigenous plants of Botswana have been so far employed in the treatment of cutaneous, subcutaneous parasitic infection, wounds, dermatological diseases, gastrointestinal system disorders, sexual dysfunction, and sexually transmitted infections. This study was conducted to identify the phytoconstituents by subjecting them to Ultrasound-Assisted Extraction (UAE) with distilled water, methanol, ethanol, chloroform, and hexane, each extract of which was further applied to the phytochemical screening through qualitative and quantitative tests. The extracting yields of Solanum aculeastrum dunal with different solvents gave the values of 13.0% (hexane), 13.0% (chloroform), 66.6% (ethanol), 66.6% (methanol) and 46.6% (aqueous), Elephantorrhiza elephentina 13.0% (hexane), 20.0% (chloroform), 66.6% (ethanol), 80.0% (methanol) and 86.0% (aqueous), Cadaba aphylla 60% (ethanol), 66.6% (methanol) and 53.3% (aqueous), Adenia glauca 40% (ethanol), 40.0% (methanol) and 46.6% (aqueous). Standards were used to determine the total content of alkaloid, flavonoid, phenol, saponin, and tannin (Atropine, Quercetin, Gallic acid, Tannic acid, and Quillaja). The regression coefficient (R2 ) was calculated and for Alkaloids, it is 0.9925, flavonoid (0.9953), phenol (0.9978), tannin (0.9955), and saponin (0.9912) respectively. These medicinal plants have produced many phytochemical substances in quantitative analysis, which will be applied in future drug analysis research","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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