Radiologia Medica最新文献

筛选
英文 中文
Multimodal prediction of major adverse cardiovascular events in hypertensive patients with coronary artery disease: integrating pericoronary fat radiomics, CT-FFR, and clinicoradiological features. 高血压合并冠心病患者主要心血管不良事件的多模式预测:整合冠状动脉周围脂肪放射组学、CT-FFR和临床放射学特征
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-21 DOI: 10.1007/s11547-025-01991-3
Qing Zou, Taichun Qiu, Chunxiao Liang, Fang Wang, Yongji Zheng, Jie Li, Xingchen Li, Yudan Li, Zhongyan Lu, Bing Ming
{"title":"Multimodal prediction of major adverse cardiovascular events in hypertensive patients with coronary artery disease: integrating pericoronary fat radiomics, CT-FFR, and clinicoradiological features.","authors":"Qing Zou, Taichun Qiu, Chunxiao Liang, Fang Wang, Yongji Zheng, Jie Li, Xingchen Li, Yudan Li, Zhongyan Lu, Bing Ming","doi":"10.1007/s11547-025-01991-3","DOIUrl":"https://doi.org/10.1007/s11547-025-01991-3","url":null,"abstract":"<p><strong>Purpose: </strong>People with both hypertension and coronary artery disease (CAD) are at a significantly increased risk of major adverse cardiovascular events (MACEs). This study aimed to develop and validate a combination model that integrates radiomics features of pericoronary adipose tissue (PCAT), CT-derived fractional flow reserve (CT-FFR), and clinicoradiological features, which improves MACE prediction within two years.</p><p><strong>Materials and methods: </strong>Coronary-computed tomography angiography data were gathered from 237 patients diagnosed with hypertension and CAD. These patients were randomly categorized into training and testing cohorts at a 7:3 ratio (165:72). The least absolute shrinkage and selection operator logistic regression and linear discriminant analysis method were used to select optimal radiomics characteristics. The predictive performance of the combination model was assessed through receiver operating characteristic curve analysis and validated via calibration, decision, and clinical impact curves.</p><p><strong>Results: </strong>The results reveal that the combination model (Radiomics.</p><p><strong>Clinical: </strong>Imaging) improves the discriminatory ability for predicting MACE. Its predictive efficacy is comparable to that of the Radiomics.Imaging model in both the training (0.886 vs. 0.872) and testing cohorts (0.786 vs. 0.815), but the combination model exhibits significantly improved specificity, accuracy, and precision. Decision and clinical impact curves further confirm the use of the combination prediction model in clinical practice.</p><p><strong>Conclusions: </strong>The combination prediction model, which incorporates clinicoradiological features, CT-FFR, and radiomics features of PCAT, is a potential biomarker for predicting MACE in people with hypertension and CAD.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
State of the art of CT myocardial perfusion. CT心肌灌注的研究现状。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2024-12-20 DOI: 10.1007/s11547-024-01942-4
Giuseppe Muscogiuri, Pierpaolo Palumbo, Kakuya Kitagawa, Satoshi Nakamura, Alberto Senatieri, Carlo Nicola De Cecco, Gabrielle Gershon, Gregorio Chierchia, Jessica Usai, Daniele Sferratore, Tommaso D'Angelo, Marco Guglielmo, Serena Dell'Aversana, Sonja Jankovic, Rodrigo Salgado, Luca Saba, Riccardo Cau, Paolo Marra, Ernesto Di Cesare, Sandro Sironi
{"title":"State of the art of CT myocardial perfusion.","authors":"Giuseppe Muscogiuri, Pierpaolo Palumbo, Kakuya Kitagawa, Satoshi Nakamura, Alberto Senatieri, Carlo Nicola De Cecco, Gabrielle Gershon, Gregorio Chierchia, Jessica Usai, Daniele Sferratore, Tommaso D'Angelo, Marco Guglielmo, Serena Dell'Aversana, Sonja Jankovic, Rodrigo Salgado, Luca Saba, Riccardo Cau, Paolo Marra, Ernesto Di Cesare, Sandro Sironi","doi":"10.1007/s11547-024-01942-4","DOIUrl":"10.1007/s11547-024-01942-4","url":null,"abstract":"<p><p>Coronary computed tomography angiography (CCTA) is a powerful tool to rule out coronary artery disease (CAD). In the last decade, myocardial perfusion CT (CTP) technique has been developed for the evaluation of myocardial ischemia, thereby increasing positive predictive value for diagnosis of obstructive CAD. A diagnostic strategy combining CCTA and perfusion acquisitions provides both anatomical coronary evaluation and functional evaluation of the stenosis, increasing the specificity and the positive predictive value of cardiac CT. This could improve risk stratification and guide revascularization procedures, reducing unnecessary diagnostic procedures in invasive coronary angiography. Two different acquisitions protocol have been developed for CTP. Static CTP allows a qualitative or semiquantitative evaluation of myocardial perfusion using a single scan during the first pass of iodinated contrast material in the myocardium. Dynamic CTP is capable of a quantitative evaluation of perfusion through multiple acquisitions, providing direct measure of the myocardial blood flow. For both, CTP acquisition hyperemia is reached using stressor agents such as adenosine or regadenoson. CTP in addition to CCTA acquisition shows good diagnostic accuracy compared to invasive fractional flow reserve (FFR). Furthermore, the evaluation of late iodine enhancement (LIE) could be performed allowing the detection of myocardial infarction.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"438-452"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The radiologist as an independent "third party" to the patient and clinicians in the era of generative AI. 在生成式人工智能时代,放射科医生作为患者和临床医生的独立“第三方”。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2025-02-26 DOI: 10.1007/s11547-025-01967-3
Anna Colarieti, Francesco Sardanelli
{"title":"The radiologist as an independent \"third party\" to the patient and clinicians in the era of generative AI.","authors":"Anna Colarieti, Francesco Sardanelli","doi":"10.1007/s11547-025-01967-3","DOIUrl":"10.1007/s11547-025-01967-3","url":null,"abstract":"<p><p>Radiologists are crucial in the diagnostic workflow. They must maintain an independent perspective, being a \"third party\" to the patients and referral clinicians. This is important when documenting the absence of relevant abnormalities or providing information that contradicts the self-reported symptoms and/or the impression of the colleagues, as well as in the case of incidental findings that impact patient management. Appropriate communication is the outcome of this professional independence, becoming more and more important in the current era of application of generative artificial intelligence to the radiological world. In fact, while radiological reports could be improved by our smart use of large language models, patients are already using such tools to understand their meaning and practical implications.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"281-283"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143503795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gut-brain axis and neuroplasticity in health and disease: a systematic review. 健康和疾病中的肠脑轴和神经可塑性:系统综述。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2024-12-24 DOI: 10.1007/s11547-024-01938-0
Alberto Di Napoli, Luca Pasquini, Emiliano Visconti, Maria Vaccaro, Maria Camilla Rossi-Espagnet, Antonio Napolitano
{"title":"Gut-brain axis and neuroplasticity in health and disease: a systematic review.","authors":"Alberto Di Napoli, Luca Pasquini, Emiliano Visconti, Maria Vaccaro, Maria Camilla Rossi-Espagnet, Antonio Napolitano","doi":"10.1007/s11547-024-01938-0","DOIUrl":"10.1007/s11547-024-01938-0","url":null,"abstract":"<p><p>The gut microbiota emerged as a potential modulator of brain connectivity in health and disease. This systematic review details current evidence on the gut-brain axis and its influence on brain connectivity. The initial set of studies included 532 papers, updated to January 2024. Studies were selected based on employed techniques. We excluded reviews, studies without connectivity focus, studies on non-human subjects. Forty-nine papers were selected. Employed techniques in healthy subjects included 15 functional magnetic resonance imaging studies (fMRI), 5 diffusion tensor imaging, (DTI) 1 electroencephalography (EEG), 6 structural magnetic resonance imaging, 2 magnetoencephalography, 1 spectroscopy, 2 arterial spin labeling (ASL); in patients 17 fMRI, 6 DTI, 2 EEG, 9 structural MRI, 1 transcranial magnetic stimulation, 1 spectroscopy, 2 R2*MRI. In healthy subjects, the gut microbiota was associated with connectivity of areas implied in cognition, memory, attention and emotions. Among the tested areas, amygdala and temporal cortex showed functional and structural differences based on bacteria abundance, as well as frontal and somatosensory cortices, especially in patients with inflammatory bowel syndrome. Several studies confirmed the connection between microbiota and brain functions in healthy subjects and patients affected by gastrointestinal to renal and psychiatric diseases.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"327-358"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Baseline 18F-FDG PET/CT for predicting pathological response to neoadjuvant chemotherapy and prognosis in locally advanced breast cancer patients: analysis of tumor and lymphoid organs metabolic parameters. 18F-FDG PET/CT基线预测局部晚期乳腺癌患者新辅助化疗病理反应及预后:肿瘤及淋巴器官代谢参数分析
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2025-02-12 DOI: 10.1007/s11547-025-01961-9
Silvia Taralli, Armando Orlandi, Pia Clara Pafundi, Valeria Tempesta, Alba Di Leone, Letizia Pontolillo, Lorenzo Scardina, Margherita Lorusso, Ida Paris, Maria Lucia Calcagni
{"title":"Baseline <sup>18</sup>F-FDG PET/CT for predicting pathological response to neoadjuvant chemotherapy and prognosis in locally advanced breast cancer patients: analysis of tumor and lymphoid organs metabolic parameters.","authors":"Silvia Taralli, Armando Orlandi, Pia Clara Pafundi, Valeria Tempesta, Alba Di Leone, Letizia Pontolillo, Lorenzo Scardina, Margherita Lorusso, Ida Paris, Maria Lucia Calcagni","doi":"10.1007/s11547-025-01961-9","DOIUrl":"10.1007/s11547-025-01961-9","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate metabolic parameters from baseline <sup>18</sup>F-FDG PET/CT as predictors of pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) and disease recurrence in locally advanced breast cancer (LABC) patients.</p><p><strong>Materials and methods: </strong>From 142 LABC in 137 patients (bilateral-synchronous BC: 5/137), the following parameters from baseline (pre-treatment) <sup>18</sup>F-FDG PET/CT were retrospectively analyzed, along with clinic-histological data: primary tumor activity (SUVmax, SUVmean, SUVpeak, tumor-to-liver ratio-TLR-, MTV, TLG); lymphoid organs activity (spleen and bone marrow SUVmax and SUVmean, spleen-to-liver ratio-SLR-, bone marrow-to-liver ratio-BLR); and PET-positive lymph-nodes' number. Predictors of pCR and recurrence-free survival (RFS) were assessed by univariable logistic regression and Cox regression (significant or suggestive association: p < 0.05; p < 0.10).</p><p><strong>Results: </strong>74/142 tumors were \"Luminal A/B HER2-\", 44/142 \"Luminal B HER2+/HER2+\", 24/142 TNBC; pCR after NAC occurred in 26/142 tumors (18.3%) and disease recurrence at follow-up (45 ± 18.1 months) in 25/127 assessable patients (19.7%). Significant or suggestive predictors of NAC response, in Luminal A/B HER2-: lower spleen SUVmax and patients' age (OR 0.06; 0.93) for pCR; lower TLRmax, TLRmean and BLRmax (OR 1.33; 1.22; and 26.42) for residual disease. Significant negative RFS predictors: higher SUVmax, SUVmean, SUVpeak (HR 1.10; 1.15; 1.11), TLRmax and TLRmean (HR 1.02; 1.00), MTV and TLG (HR 1.32; 1.26) in Luminal A/B HER2-; higher spleen SUVmax, PET-positive nodes' number and patients' age (HR 6.24; 1.20; 1.08) in Luminal B HER2+/HER2+.</p><p><strong>Conclusion: </strong>Primary tumor and lymphoid organs parameters at baseline <sup>18</sup>F-FDG PET/CT resulted as predictors of NAC response and prognosis in LABC patients, respectively, reflecting the BC cells' proliferative activity and metabolic burden, and the role of tumor-induced immune-system activation on tumors' behavior and treatment responsiveness. In LABC candidates to NAC, baseline PET information could improve treatment planning and prognostic stratification.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"422-437"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weight censorial score: estimation of the weight loss during concurrent chemo-radiotherapy in nasopharyngeal carcinoma patients by image features predicts prognosis. 体重检查评分:通过影像特征估计鼻咽癌患者同步放化疗期间体重减轻情况预测预后。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2025-01-28 DOI: 10.1007/s11547-025-01953-9
Jiachen Sun, Sai Kit Edmond Lam, Jiang Zhang, Xinzhi Teng, Francis Kar-Ho Lee, Celia Wai-Yi Yip, James Chung Hang Chow, Victor Ho Fun Lee, Ying Sun, Jing Cai
{"title":"Weight censorial score: estimation of the weight loss during concurrent chemo-radiotherapy in nasopharyngeal carcinoma patients by image features predicts prognosis.","authors":"Jiachen Sun, Sai Kit Edmond Lam, Jiang Zhang, Xinzhi Teng, Francis Kar-Ho Lee, Celia Wai-Yi Yip, James Chung Hang Chow, Victor Ho Fun Lee, Ying Sun, Jing Cai","doi":"10.1007/s11547-025-01953-9","DOIUrl":"10.1007/s11547-025-01953-9","url":null,"abstract":"<p><strong>Purpose: </strong>Bodyweight loss is commonly found in Nasopharyngeal Carcinoma patients during Concurrent Chemo-radiotherapy (CCRT) and has implications for treatment decisions. However, the prognostic value of this weight loss remains uncertain. We addressed it by proposing a novel index Weight Censorial Score (WCS) that characterizes the patient-specific CCRT response on actual to estimated weight loss.</p><p><strong>Methods: </strong>A retrospective study included 315 patients from two independent hospitals. An Estimated WCS (eWCS) was obtained through linear regression of image and dosimetry features. The eWCS was converted to an estimated net weight loss (nWL), with its accuracy evaluated. The Determined WCS (dWCS) was calculated by centering and scaling the post-RT actual nWL with patient's pre-RT body information. The ratio of dWCS to eWCS (WCS ratio) reflected the actual to estimated weight loss of a patient. The prognostic ability of WCS ratio dichotomized at 1 was evaluated.</p><p><strong>Results: </strong>The mean absolute error of estimated to actual nWL was 1.84 kg. Patients who had their actual WL larger than estimated WL were found to have significantly worse OS (p = 0.005, HR = 3.35[1.45-7.73]), PFS (p = 0.038, HR = 1.86[1.03-3.35]), and DMFS (p = 0.050, HR = 2.20[1.00-4.85]), respectively, in multivariable cox analysis. They were also found not to benefit from adjuvant chemotherapy (p = 0.572), whereas the adjuvant chemotherapy provided significant PFS benefit in patients with actual WL smaller than estimated WL (p = 0.036, HR = 0.53[0.29-0.96]).</p><p><strong>Conclusion: </strong>The nWL of patient during CCRT can be reasonably estimated by dosimetry factors at pre-RT stage. The prognostic value of the actual to expected weight loss holds promise for highlighting vulnerable patients after CCRT.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"381-396"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11903536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shapley-based saliency maps improve interpretability of vertebral compression fractures classification: multicenter study. 基于shapley的显著性图提高椎体压缩性骨折分类的可解释性:多中心研究。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2025-02-24 DOI: 10.1007/s11547-025-01968-2
Liang Xia, Jun Zhang, Zhipeng Liang, Jun Tang, Jianguo Xia, Yongkang Liu
{"title":"Shapley-based saliency maps improve interpretability of vertebral compression fractures classification: multicenter study.","authors":"Liang Xia, Jun Zhang, Zhipeng Liang, Jun Tang, Jianguo Xia, Yongkang Liu","doi":"10.1007/s11547-025-01968-2","DOIUrl":"10.1007/s11547-025-01968-2","url":null,"abstract":"<p><strong>Purpose: </strong>Evaluate the classification performance and interpretability of the Vision Transformer (ViT) model on acute and chronic vertebral compression fractures using Shapley significance maps.</p><p><strong>Materials and methods: </strong>This retrospective study utilized medical imaging data from December 2018 to December 2023 from three hospitals in China. The study included 942 patients, with imaging data comprising X-rays, CTs, and MRIs. Patients were divided into training, validation, and test sets with a ratio of 7:2:1. The ViT model variant, SimpleViT, was fine-tuned on the training dataset. Statistical analyses were performed using the PixelMedAI platform, focusing on metrics such as ROC curves, sensitivity, specificity, and AUC values, with statistical significance assessed using the DeLong test.</p><p><strong>Results: </strong>A total of 942 patients (mean age 69.17 ± 10.61 years) were included, with 1076 vertebral fractures analyzed (705 acute, 371 chronic). In the test set, the ViT model demonstrated superior performance over the ResNet18 model, with an accuracy of 0.880 and an AUC of 0.901 compared to 0.843 and 0.833, respectively. The use of ViT Shapley saliency maps significantly enhanced diagnostic sensitivity and specificity, reaching 0.883 (95% CI: 0.800, 0.963) and 0.950 (95% CI: 0.891, 1.00), respectively.</p><p><strong>Conclusion: </strong>In vertebral compression fractures classification, Vision Transformer outperformed Convolutional Neural Network, providing more effective Shapley-based saliency maps that were favored by radiologists over GradCAM.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"412-421"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive CT study to assess local and systemic involvement in patients with infective endocarditis: experience from a multidisciplinary team of a tertiary referral center. 综合CT研究评估局部和全身累及感染性心内膜炎患者:来自三级转诊中心多学科团队的经验。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2025-02-12 DOI: 10.1007/s11547-025-01960-w
Anna Palmisano, Elisa Bruno, Davide Vignale, Ludovica Bognoni, Raffaele Ascione, Giacomo Ingallina, Paolo Scarpellini, Marco Ripa, Silvia Carletti, Andrea Bettinelli, Roberto Mapelli, Elena Busnardo, Ursula Pajoro, Benedetto Del Forno, Cinzia Trumello, Elisabetta La Penna, Francesco Maisano, Michele De Bonis, Eustachio Agricola, Antonio Esposito
{"title":"Comprehensive CT study to assess local and systemic involvement in patients with infective endocarditis: experience from a multidisciplinary team of a tertiary referral center.","authors":"Anna Palmisano, Elisa Bruno, Davide Vignale, Ludovica Bognoni, Raffaele Ascione, Giacomo Ingallina, Paolo Scarpellini, Marco Ripa, Silvia Carletti, Andrea Bettinelli, Roberto Mapelli, Elena Busnardo, Ursula Pajoro, Benedetto Del Forno, Cinzia Trumello, Elisabetta La Penna, Francesco Maisano, Michele De Bonis, Eustachio Agricola, Antonio Esposito","doi":"10.1007/s11547-025-01960-w","DOIUrl":"10.1007/s11547-025-01960-w","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the value of a computed tomography (CT) protocol, including ECG-gated cardiac angiographic and venous phase, in patients with infective endocarditis (IE).</p><p><strong>Material and methods: </strong>From January 2019 to October 2022, consecutive patients with IE submitted to total-body CT, including ECG-gated cardiac acquisition in angiographic and venous phase, were enrolled. Transesophageal echocardiography was performed in all cases. Rate of local complications including vegetation, pseudoaneurysm, abscess, fistula and valve dehiscence was compared in CT and echocardiography. Systemic embolization was identified through CT scans.</p><p><strong>Results: </strong>Seventy-six adults (median age 69 [IQR 55-77] years old; males 54/76, 71%] were enrolled. Most patients underwent surgery (51/76, 67%), and the in-hospital mortality rate was 8% (6/76). CT showed higher detection rate of valve vegetation compared to echocardiography (67/76, 88% vs 58/76, 76%; p = 0.008), including vegetation smaller than 10 mm (24/76, 36% vs 16/76, 28%; p = 0.013) and higher detection rate of pseudoaneurysm and abscess (p = 0.004 and p = 0.009, respectively). Abscess showed higher contrast-to-noise ratio (CNR) in the venous scan compared to angiographic scan (2.75 [IQR 2.27; 5.17] vs 1.97 [IQR 1.21; 3.32], p = 0.039) and higher density of perivalvular and epicardial fat compared to pseudoaneurysm (35 [IQR 31; 52]HU and - 50 [IQR - 62; - 35]HU versus 52 [IQR - 60; - 18]HU; p = 0.001, and - 91 [IQR - 95; - 81]HU; p = 0.007, respectively), for greater inflammation. CT overestimated valve dehiscence when compared to echocardiography and surgery.</p><p><strong>Conclusion: </strong>A comprehensive CT study enhances the diagnostic assessment of patients with IE, not only by detecting distant sites of embolization, but also increasing sensitivity for valve vegetation and local complications.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"302-314"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polyethylene Glycol microspheres for uterine artery embolization for the treatment of symptomatic uterine fibroids. 聚乙二醇微球用于子宫动脉栓塞治疗症状性子宫肌瘤。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2025-01-20 DOI: 10.1007/s11547-025-01955-7
Floriana Nardelli, Fernanda Ciferri, Pierluigi Muratore, Federica Fumarola, Riccardo Faletti, Maria Antonella Ruffino, Marco Calandri, Valeria Accortanzo, Paolo Cortese, Andrea Discalzi
{"title":"Polyethylene Glycol microspheres for uterine artery embolization for the treatment of symptomatic uterine fibroids.","authors":"Floriana Nardelli, Fernanda Ciferri, Pierluigi Muratore, Federica Fumarola, Riccardo Faletti, Maria Antonella Ruffino, Marco Calandri, Valeria Accortanzo, Paolo Cortese, Andrea Discalzi","doi":"10.1007/s11547-025-01955-7","DOIUrl":"10.1007/s11547-025-01955-7","url":null,"abstract":"<p><strong>Background: </strong>Uterine fibroids are prevalent benign pelvic tumors, often causing debilitating symptoms that impair quality of life. Uterine fibroid embolization (UFE) is a consolidated minimally invasive treatment option. The purpose of this study is to report our experience with polyethylene glycol microspheres (HydroPearl) in UFE for symptomatic patients.</p><p><strong>Methods: </strong>This single-center retrospective study evaluated 37 consecutive patients with symptomatic uterine fibroids referred to our institution since November 2016 to February 2020 for UFE with HydroPearl microspheres. All patients included completed a comprehensive pre-UFE clinical assessment and underwent a magnetic resonance imaging (MRI) pre- and post-procedure. Technical success, procedure-related complications, clinical outcomes, follow-up MRI findings, and patient satisfaction were evaluated.</p><p><strong>Results: </strong>A technical success rate of 97% with complete bilateral uterine artery embolization was achieved. Significant improvements were observed in menorrhagia, bulk-type symptoms, abdominal pain, and urinary dysfunctions after UFE. Post-procedural MRI assessments demonstrated reductions in uterine and dominant fibroid volumes, indicating successful devascularization. No immediate procedural complications were reported. Symptoms interfering with everyday activities significantly improved after the procedure. Patient satisfaction was high, with 89% expressing satisfaction with the treatment and 84% indicating purpose to repeat the procedure if necessary.</p><p><strong>Conclusions: </strong>Uterine artery embolization with HydroPearl is a safe and effective treatment option for symptomatic uterine fibroids. A significant improvement in menorrhagia and bulk-type symptoms after the procedure was observed correlated by a reduction in diameters and volumes of both the uterus and the main fibroid in post-procedural MRI.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"315-326"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Importance of technıcal standardızatıon on ultrasound-based lıver fat quantıfıcatıon. technıcal standardızatıon对基于超声的lıver脂肪quantıfıcatıon的重要性。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2025-03-01 Epub Date: 2025-01-15 DOI: 10.1007/s11547-025-01948-6
Halit Nahit Şendur, Mahi Nur Cerit, Atiye Cenay Karabörk Kılıç, Ethem Turgay Cerit
{"title":"Importance of technıcal standardızatıon on ultrasound-based lıver fat quantıfıcatıon.","authors":"Halit Nahit Şendur, Mahi Nur Cerit, Atiye Cenay Karabörk Kılıç, Ethem Turgay Cerit","doi":"10.1007/s11547-025-01948-6","DOIUrl":"10.1007/s11547-025-01948-6","url":null,"abstract":"","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"284-285"},"PeriodicalIF":9.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信