A systematic review and meta-analysis on the concept of bone quality in dento-maxillofacial Cone Beam Computed Tomography.

IF 4.8 1区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiologia Medica Pub Date : 2025-08-01 Epub Date: 2025-07-16 DOI:10.1007/s11547-025-02052-5

Fabio Mistretta, Andrea Magnini, Lorenzo Cinci, Patrizio Zanobini, Maria Pisano, Eleonora Barcali, Leonardo Bocchi, Cosimo Nardi

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引用次数: 0

Abstract

Objectives: Bone quality is currently considered a set of intrinsic characteristics of the bone, among which macro- and microarchitecture of the trabecular bone tissue stands out. The investigation of bone quality is crucial in maxillofacial area and especially in dental implant planning. Nevertheless, there is currently no consensus about what bone quality really represents. The aim of this study was to investigate the role of CBCT in assessing bone quality of mandibular and maxillary bones.

Methods: This systematic review included fourteen articles selected via PubMed, Embase, and Web of Science databases, with the following features: samples of maxillary or mandibular bones from living individuals or corpses; CBCT as diagnostic investigation tool; a reference standard in assessing bone quality. Ten studies using µCT as reference standard were included in the meta-analysis.

Results: CBCT voxel size was from 80 to 400 µm. Only half of the studies evaluated a considerable number of morphometric parameters as described by the Society for Bone and Mineral Research. Meta-analysis was only possible for the 3D Accuitomo 170 CBCT scanner with a voxel size of 80 µm. Trabecular separation (Tb.Sp) and Degree of Anisotropy (DA) microstructural parameters showed moderate to low heterogeneity among studies without significative differences between CBCT and μCT.

Conclusions: High-resolution CBCT with a voxel size down to 80 μm should be considered a suitable tool for the assessment of bone microarchitecture. Tb.Sp and DA showed similar values between CBCT and μCT and they could thus be considered as reliable tools for the assessment of bone quality with CBCT. Nevertheless, the high heterogeneity in several bone microstructural parameters and the lack of standardization both in imaging protocols and in image analysis software made CBCT not adequate to be currently deemed the gold standard technique for the assessment of jawbones quality.

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牙颌面锥束计算机断层扫描中骨质量概念的系统回顾和荟萃分析。

目的：骨质量目前被认为是骨的一系列内在特征，其中骨小梁组织的宏观和微观结构尤为突出。骨质量的研究在颌面区，特别是种植体规划中是至关重要的。然而，目前对于骨质量究竟代表什么还没有达成共识。本研究的目的是探讨CBCT在评估下颌骨和上颌骨的骨质量中的作用。方法：本系统综述从PubMed、Embase和Web of Science数据库中选择了14篇文章，具有以下特征：来自活体个体或尸体的上颌或下颌骨样本；CBCT作为诊断调查工具；评价骨质量的参考标准。meta分析纳入了10项以µCT为参比标准的研究。结果：CBCT体素大小为80 ~ 400µm。只有一半的研究评估了骨与矿物研究协会所描述的相当数量的形态测量参数。荟萃分析仅适用于体素尺寸为80µm的3D Accuitomo 170 CBCT扫描仪。小梁分离度（Tb.Sp）和各向异性度（DA）微观结构参数在各研究间呈中等至低异质性，CBCT与μCT间无显著差异。结论：体素尺寸小于80 μm的高分辨率CBCT可作为评估骨微结构的合适工具。结核病。Sp和DA在CBCT和μCT之间的值相近，可作为CBCT评价骨质量的可靠工具。然而，由于几种骨微结构参数的高度异质性以及成像方案和图像分析软件的缺乏标准化，使得CBCT目前不足以被认为是评估颌骨质量的金标准技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiologia Medica 医学-核医学

CiteScore

14.10

自引率

7.90%

发文量

133

审稿时长

4-8 weeks

期刊介绍： Felice Perussia founded La radiologia medica in 1914. It is a peer-reviewed journal and serves as the official journal of the Italian Society of Medical and Interventional Radiology (SIRM). The primary purpose of the journal is to disseminate information related to Radiology, especially advancements in diagnostic imaging and related disciplines. La radiologia medica welcomes original research on both fundamental and clinical aspects of modern radiology, with a particular focus on diagnostic and interventional imaging techniques. It also covers topics such as radiotherapy, nuclear medicine, radiobiology, health physics, and artificial intelligence in the context of clinical implications. The journal includes various types of contributions such as original articles, review articles, editorials, short reports, and letters to the editor. With an esteemed Editorial Board and a selection of insightful reports, the journal is an indispensable resource for radiologists and professionals in related fields. Ultimately, La radiologia medica aims to serve as a platform for international collaboration and knowledge sharing within the radiological community.