Radiologia Medica最新文献

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Background parenchymal enhancement on contrast-enhanced mammography: associations with breast density and patient's characteristics. 对比增强乳腺 X 射线造影术的背景实质增强:与乳腺密度和患者特征的关系。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-07-26 DOI: 10.1007/s11547-024-01860-5
Veronica Magni, Andrea Cozzi, Giulia Muscogiuri, Adrienn Benedek, Gabriele Rossini, Marianna Fanizza, Giuseppe Di Giulio, Francesco Sardanelli
{"title":"Background parenchymal enhancement on contrast-enhanced mammography: associations with breast density and patient's characteristics.","authors":"Veronica Magni, Andrea Cozzi, Giulia Muscogiuri, Adrienn Benedek, Gabriele Rossini, Marianna Fanizza, Giuseppe Di Giulio, Francesco Sardanelli","doi":"10.1007/s11547-024-01860-5","DOIUrl":"10.1007/s11547-024-01860-5","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate if background parenchymal enhancement (BPE) on contrast-enhanced mammography (CEM), graded according to the 2022 CEM-dedicated Breast Imaging Reporting and Data System (BI-RADS) lexicon, is associated with breast density, menopausal status, and age.</p><p><strong>Methods: </strong>This bicentric retrospective analysis included CEM examinations performed for the work-up of suspicious mammographic findings. Three readers independently and blindly evaluated BPE on recombined CEM images and breast density on low-energy CEM images. Inter-reader reliability was estimated using Fleiss κ. Multivariable binary logistic regression was performed, dichotomising breast density and BPE as low (a/b BI-RADS categories, minimal/mild BPE) and high (c/d BI-RADS categories, moderate/marked BPE).</p><p><strong>Results: </strong>A total of 200 women (median age 56.8 years, interquartile range 50.5-65.6, 140/200 in menopause) were included. Breast density was classified as a in 27/200 patients (13.5%), as b in 110/200 (55.0%), as c in 52/200 (26.0%), and as d in 11/200 (5.5%), with moderate inter-reader reliability (κ = 0.536; 95% confidence interval [CI] 0.482-0.590). BPE was minimal in 95/200 patients (47.5%), mild in 64/200 (32.0%), moderate in 25/200 (12.5%), marked in 16/200 (8.0%), with substantial inter-reader reliability (κ = 0.634; 95% CI 0.581-0.686). At multivariable logistic regression, premenopausal status and breast density were significant positive predictors of high BPE, with adjusted odds ratios of 6.120 (95% CI 1.847-20.281, p = 0.003) and 2.416 (95% CI 1.095-5.332, p = 0.029) respectively.</p><p><strong>Conclusion: </strong>BPE on CEM is associated with well-established breast cancer risk factors, being higher in women with higher breast density and premenopausal status.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1303-1312"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MRI-guided transrectal prostate laser ablation for benign prostatic hypertrophy: a retrospective cohort study. 磁共振成像引导下经直肠前列腺激光消融术治疗良性前列腺肥大:一项回顾性队列研究。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-08-18 DOI: 10.1007/s11547-024-01855-2
Aaron Harman, Robert Toth, Zahra Mobley, Donnie Sartin, Ara Karamanian
{"title":"MRI-guided transrectal prostate laser ablation for benign prostatic hypertrophy: a retrospective cohort study.","authors":"Aaron Harman, Robert Toth, Zahra Mobley, Donnie Sartin, Ara Karamanian","doi":"10.1007/s11547-024-01855-2","DOIUrl":"10.1007/s11547-024-01855-2","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate whether MRI-guided transrectal laser ablation is safe and effective for the treatment of lower urinary tract symptoms caused by BPH.</p><p><strong>Materials and methods: </strong>This single-center retrospective cohort study evaluated men who underwent MRI-guided transrectal laser ablation for BPH between February 2017 and July 2021. Age, prostate-specific antigen, prostate volume, prior surgical BPH treatments if any, International Prostate Symptom Score (IPSS) and Sexual Health Inventory of Men (SHIM) were collected. The primary outcome measures assessed were change in IPSS and SHIM 6, 12 and 24 months after laser ablation and adverse events.</p><p><strong>Results: </strong>Fifty-two patients were included, having completed at least one follow-up survey. The mean patient age was 62.9 ± 5.7 years, and mean prostate volume was 80.2 ± 39.2 cc. Eighteen patients (34.6%) had received a prior BPH treatment. The IPSS scores dropped an average of 16.7 ± 7.0 (p < 0.001), 16.9 ± 7.5 (p < 0.001) and 17.1 ± 7.2 (p < 0.001) points from baseline at 6, 12 and 24 months, respectively. There was no statistically significant difference in IPSS score drop between patients who had received a prior BPH procedure and those who had not (p = 0.628). The SHIM scores showed a statistically insignificant increase at all time points. Nineteen patients (36.5%) reported a complication. There were 12 grade II complications (23%) and seven grade I complications (13.5%). There were no grade III or higher complications.</p><p><strong>Conclusion: </strong>Transrectal MRI-guided focal laser ablation is safe and effective for the treatment of lower urinary tract symptoms caused by BPH, with a significant improvement in symptom severity after 2 years.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1412-1423"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141996338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between mpMRI detected tumor apparent diffusion coefficient and 5-year biochemical recurrence risk after radical prostatectomy. mpMRI 检测到的肿瘤表观弥散系数与根治性前列腺切除术后 5 年生化复发风险之间的关系。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-07-16 DOI: 10.1007/s11547-024-01857-0
Sarah Alessi, Roberta Maggioni, Stefano Luzzago, Paul E Summers, Giuseppe Renne, Fabio Zugni, Maddalena Belmonte, Sara Raimondi, Silvano Vignati, Francesco A Mistretta, Letizia Di Meglio, Elisa D'Ascoli, Alice Scarabelli, Giulia Marvaso, Ottavio De Cobelli, Gennaro Musi, Barbara Alicja Jereczek-Fossa, Giuseppe Curigliano, Giuseppe Petralia
{"title":"Association between mpMRI detected tumor apparent diffusion coefficient and 5-year biochemical recurrence risk after radical prostatectomy.","authors":"Sarah Alessi, Roberta Maggioni, Stefano Luzzago, Paul E Summers, Giuseppe Renne, Fabio Zugni, Maddalena Belmonte, Sara Raimondi, Silvano Vignati, Francesco A Mistretta, Letizia Di Meglio, Elisa D'Ascoli, Alice Scarabelli, Giulia Marvaso, Ottavio De Cobelli, Gennaro Musi, Barbara Alicja Jereczek-Fossa, Giuseppe Curigliano, Giuseppe Petralia","doi":"10.1007/s11547-024-01857-0","DOIUrl":"10.1007/s11547-024-01857-0","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the ability of tumor apparent diffusion coefficient (ADC) values obtained from multiparametric magnetic resonance imaging (mpMRI) to predict the risk of 5-year biochemical recurrence (BCR) after radical prostatectomy (RP).</p><p><strong>Materials and methods: </strong>This retrospective analysis included 1207 peripheral and 232 non-peripheral zone prostate cancer (PCa) patients who underwent mpMRI before RP (2012-2015), with the outcome of interest being 5-year BCR. ADC was evaluated as a continuous variable and as categories: low (< 850 µm<sup>2</sup>/s), intermediate (850-1100 µm<sup>2</sup>/s), and high (> 1100 µm<sup>2</sup>/s). Kaplan-Meier curves with log-rank testing of BCR-free survival, multivariable Cox proportional hazard regression models were formed to estimate the risk of BCR.</p><p><strong>Results: </strong>Among the 1439 males with median age 63 (± 7) years, the median follow-up was 59 months, and 306 (25%) patients experienced BCR. Peripheral zone PCa patients with BCR had lower tumor ADC values than those without BCR (874 versus 1025 µm<sup>2</sup>/s, p < 0.001). Five-year BCR-free survival rates were 52.3%, 74.4%, and 87% for patients in the low, intermediate, and high ADC value categories, respectively (p < 0.0001). Lower ADC was associated with BCR, both as continuously coded variable (HR: 5.35; p < 0.001) and as ADC categories (intermediate versus high ADC-HR: 1.56, p = 0.017; low vs. high ADC-HR; 2.36, p < 0.001). In the non-peripheral zone PCa patients, no association between ADC and BCR was observed.</p><p><strong>Conclusion: </strong>Tumor ADC values and categories were found to be predictive of the 5-year BCR risk after RP in patients with peripheral zone PCa and may serve as a prognostic biomarker.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1394-1404"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141627509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of abdominal artery delineation by photon-counting detector CT. 光子计数探测器 CT 对腹部动脉划线的研究。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-07-24 DOI: 10.1007/s11547-024-01858-z
Takashi Ota, Hiromitsu Onishi, Toshihide Itoh, Hideyuki Fukui, Takahiro Tsuboyama, Atsushi Nakamoto, Yukihiro Enchi, Mitsuaki Tatsumi, Noriyuki Tomiyama
{"title":"Investigation of abdominal artery delineation by photon-counting detector CT.","authors":"Takashi Ota, Hiromitsu Onishi, Toshihide Itoh, Hideyuki Fukui, Takahiro Tsuboyama, Atsushi Nakamoto, Yukihiro Enchi, Mitsuaki Tatsumi, Noriyuki Tomiyama","doi":"10.1007/s11547-024-01858-z","DOIUrl":"10.1007/s11547-024-01858-z","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the ability of 50-keV virtual monoenergetic images (VMI) to depict abdominal arteries in abdominal CT angiography (CTA) compared with 70-keV VMI with photon-counting detector CT (PCD-CT).</p><p><strong>Methods: </strong>Fifty consecutive patients who underwent multiphase abdominal scans between March and April 2023 were included. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were quantitatively assessed for the abdominal aorta (AA), celiac artery (CeA), superior mesenteric artery (SMA), renal artery (RA), and right hepatic artery (RHA) at both 50- and 70-keV VMI. In addition, 3D images from CTA were analyzed to measure arterial lengths and evaluate the visualization of distal branches.</p><p><strong>Results: </strong>Significantly higher SNR and CNR were observed at 50-keV compared to 70-keV VMI for all arteries: AA (36.54 and 48.28 vs. 25.70 and 28.46), CeA (22.39 and 48.38 vs. 19.09 and 29.15), SMA (23.34 and 49.34 vs. 19.67 and 29.71), RA (22.88 and 48.84 vs. 20.15 and 29.41), and RHA (14.38 and 44.41 vs. 13.45 and 27.18), all p < 0.05. Arterial lengths were also significantly longer at 50-keV: RHA (192.6 vs. 180.3 mm), SMA (230.9 vs. 216.5 mm), and RA (95.9 vs. 92.0 mm), all p < 0.001.</p><p><strong>Conclusion: </strong>In abdominal CTA with PCD-CT, 50-keV VMI demonstrated superior quantitative image quality compared to 70-keV VMI. In addition, 50-keV VMI 3D CTA allowed better visualization of abdominal artery branches, highlighting its potential clinical advantage for improved imaging and detailed assessment of abdominal arteries.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1265-1274"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of an expert-derived, quick hands-on tool on classifying pulmonary hypertension in chest computed tomography: a study on inexperienced readers using RAPID-CT-PH. 源自专家的快速上手工具对胸部计算机断层扫描肺动脉高压分类的影响:使用 RAPID-CT-PH 对缺乏经验的读者进行的研究。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-07-24 DOI: 10.1007/s11547-024-01852-5
Lorenzo Cereser, Gaia Zussino, Carmelo Cicciò, Annarita Tullio, Chiara Montanaro, Mauro Driussi, Emma Di Poi, Vincenzo Patruno, Chiara Zuiani, Rossano Girometti
{"title":"Impact of an expert-derived, quick hands-on tool on classifying pulmonary hypertension in chest computed tomography: a study on inexperienced readers using RAPID-CT-PH.","authors":"Lorenzo Cereser, Gaia Zussino, Carmelo Cicciò, Annarita Tullio, Chiara Montanaro, Mauro Driussi, Emma Di Poi, Vincenzo Patruno, Chiara Zuiani, Rossano Girometti","doi":"10.1007/s11547-024-01852-5","DOIUrl":"10.1007/s11547-024-01852-5","url":null,"abstract":"<p><strong>Purpose: </strong>To test the inter-reader agreement in classifying pulmonary hypertension (PH) on chest contrast-enhanced computed tomography (CECT) between a consensus of two cardio-pulmonary-devoted radiologists (CRc) and inexperienced readers (radiology residents, RRs) when using a CECT-based quick hands-on tool built upon PH imaging literature, i.e., the \"Rapid Access and Practical Information Digest on Computed Tomography for PH-RAPID-CT-PH\".</p><p><strong>Material and methods: </strong>The observational study retrospectively included 60 PH patients who underwent CECT between 2015 and 2022. Four RRs independently reviewed all CECTs and classified each case into one of the five PH groups per the 2022 ESC/ERS guidelines. While RR3 and RR4 (RAPID-CT-PH group) used RAPID-CT-PH, RR1 and RR2 (control group) did not. RAPID-CT-PH and control groups' reports were compared with CRc using unweighted Cohen's Kappa (k) statistics. RRs' report completeness and reporting time were also compared using the Wilcoxon-Mann-Whitney test.</p><p><strong>Results: </strong>The inter-reader agreement in classifying PH between the RAPID-CT-PH group and CRc was substantial (k = 0.75 for RR3 and k = 0.65 for RR4); while, it was only moderate for the control group (k = 0.57 for RR1 and k = 0.49 for RR2). Using RAPID-CT-PH resulted in significantly higher report completeness (all p < 0.0001) and significantly lower reporting time (p < 0.0001) compared to the control group.</p><p><strong>Conclusion: </strong>RRs using RAPID-CT-PH showed a substantial agreement with CRc on CECT-based PH classification. RAPID-CT-PH improved report completeness and reduced reporting time. A quick hands-on tool for classifying PH on chest CECT may help inexperienced radiologists effectively contribute to the PH multidisciplinary team.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1313-1328"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141760603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Budget impact analysis of introducing digital breast tomosynthesis in breast cancer screening in Italy. 意大利在乳腺癌筛查中引入数字乳腺断层合成技术的预算影响分析。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-08-20 DOI: 10.1007/s11547-024-01850-7
Olivera Djuric, Silvia Deandrea, Paola Mantellini, Francesco Sardanelli, Francesco Venturelli, Stefania Montemezzi, Riccardo Vecchio, Lauro Bucchi, Carlo Senore, Livia Giordano, Eugenio Paci, Adriana Bonifacino, Massimo Calabrese, Francesca Caumo, Flori Degrassi, Priscilla Sassoli De' Bianchi, Francesca Battisti, Marco Zappa, Pierpaolo Pattacini, Cinzia Campari, Andrea Nitrosi, Giovanni Di Leo, Alfonso Frigerio, Veronica Magni, Francesca Fornasa, Giovanna Romanucci, Patrizia Falini, Noemi Auzzi, Paola Armaroli, Paolo Giorgi Rossi
{"title":"Budget impact analysis of introducing digital breast tomosynthesis in breast cancer screening in Italy.","authors":"Olivera Djuric, Silvia Deandrea, Paola Mantellini, Francesco Sardanelli, Francesco Venturelli, Stefania Montemezzi, Riccardo Vecchio, Lauro Bucchi, Carlo Senore, Livia Giordano, Eugenio Paci, Adriana Bonifacino, Massimo Calabrese, Francesca Caumo, Flori Degrassi, Priscilla Sassoli De' Bianchi, Francesca Battisti, Marco Zappa, Pierpaolo Pattacini, Cinzia Campari, Andrea Nitrosi, Giovanni Di Leo, Alfonso Frigerio, Veronica Magni, Francesca Fornasa, Giovanna Romanucci, Patrizia Falini, Noemi Auzzi, Paola Armaroli, Paolo Giorgi Rossi","doi":"10.1007/s11547-024-01850-7","DOIUrl":"10.1007/s11547-024-01850-7","url":null,"abstract":"<p><strong>Purpose: </strong>This study quantifies the impact on budget and cost per health benefit of implementing digital breast tomosynthesis (DBT) in place of digital mammography (DM) for breast cancer screening among asymptomatic women in Italy.</p><p><strong>Methods: </strong>A budget impact analysis and a cost consequence analysis were conducted using parameters from the MAITA project and literature. The study considered four scenarios for DBT implementation, i.e., DBT for all women, DBT for women aged 45-49 years, DBT based on breast density (BI-RADS C + D or D only), and compared these to the current DM screening. Healthcare provider's perspective was adopted, including screening, diagnosis, and cancer treatment costs.</p><p><strong>Results: </strong>Introducing DBT for all women would increase overall screening costs by 20%. Targeting DBT to women aged 45-49 years or with dense breasts would result in smaller cost increases (3.2% for age-based and 1.4-10.7% for density-based scenarios). The cost per avoided interval cancer was significantly higher when DBT was applied to all women compared to targeted approaches. The cost per gained early-detected cancer slightly increases in targeted approaches, while the assumptions on the clinical significance and overdiagnosis of cancers detected by DBT and not by DM have a strong impact.</p><p><strong>Conclusions: </strong>Implementing DBT as a primary breast cancer test in screening programs in Italy would lead to a substantial increase in costs. Tailoring DBT use to women aged 45-49 or with dense breasts could enhance the feasibility and sustainability of the intervention. Further research is needed to clarify the impact of DBT on overdiagnosis and the long-term outcomes.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1288-1302"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to editor on the article "assessment of post-thrombectomy brain hemorrhage in acute ischemic stroke with dual-energy CT: how reliable is it in clinical practice?" by Pacielli et al. 就 Pacielli 等人撰写的文章 "用双能 CT 评估急性缺血性脑卒中血栓切除术后脑出血:在临床实践中的可靠性如何?
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-06-19 DOI: 10.1007/s11547-024-01834-7
Yang Yang, Kunhua Li
{"title":"Letter to editor on the article \"assessment of post-thrombectomy brain hemorrhage in acute ischemic stroke with dual-energy CT: how reliable is it in clinical practice?\" by Pacielli et al.","authors":"Yang Yang, Kunhua Li","doi":"10.1007/s11547-024-01834-7","DOIUrl":"10.1007/s11547-024-01834-7","url":null,"abstract":"","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1424-1425"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141420517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply letter to Dr. Li and colleagues. 给李博士及其同事的回信。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-08-01 DOI: 10.1007/s11547-024-01866-z
Alberto Pacielli
{"title":"Reply letter to Dr. Li and colleagues.","authors":"Alberto Pacielli","doi":"10.1007/s11547-024-01866-z","DOIUrl":"10.1007/s11547-024-01866-z","url":null,"abstract":"","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1426-1427"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141875805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ASL, DSC, DCE perfusion MRI and 18F-DOPA PET/CT in differentiating glioma recurrence from post-treatment changes. ASL、DSC、DCE 灌注磁共振成像和 18F-DOPA PET/CT 在区分胶质瘤复发与治疗后变化方面的作用。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 Epub Date: 2024-08-08 DOI: 10.1007/s11547-024-01862-3
Giulia Moltoni, Andrea Romano, Gabriela Capriotti, Giuseppe Campagna, Anna Maria Ascolese, Allegra Romano, Francesco Dellepiane, Giuseppe Minniti, Alberto Signore, Alessandro Bozzao
{"title":"ASL, DSC, DCE perfusion MRI and 18F-DOPA PET/CT in differentiating glioma recurrence from post-treatment changes.","authors":"Giulia Moltoni, Andrea Romano, Gabriela Capriotti, Giuseppe Campagna, Anna Maria Ascolese, Allegra Romano, Francesco Dellepiane, Giuseppe Minniti, Alberto Signore, Alessandro Bozzao","doi":"10.1007/s11547-024-01862-3","DOIUrl":"10.1007/s11547-024-01862-3","url":null,"abstract":"<p><strong>Objectives: </strong>To discriminate between post-treatment changes and tumor recurrence in patients affected by glioma undergoing surgery and chemoradiation with a new enhancing lesion is challenging. We aimed to evaluate the role of ASL, DSC, DCE perfusion MRI, and 18F-DOPA PET/CT in distinguishing tumor recurrence from post-treatment changes in patients with glioma.</p><p><strong>Materials and methods: </strong>We prospectively enrolled patients with treated glioma (surgery plus chemoradiation) and a new enhancing lesion doubtful for recurrence or post-treatment changes. Each patient underwent a 1.5T MRI examination, including ASL, DSC, and DCE PWI, and an <sup>18</sup>F-DOPA PET/CT examination. For each lesion, we measured ASL-derived CBF and normalized CBF, DSC-derived rCBV, DCE-derived Ktrans, Vp, Ve, Kep, and PET/CT-derived SUV maximum. Clinical and radiological follow-up determined the diagnosis of tumor recurrence or post-treatment changes.</p><p><strong>Results: </strong>We evaluated 29 lesions (5 low-grade gliomas and 24 high-grade gliomas); 14 were malignancies, and 15 were post-treatment changes. CBF ASL, nCBF ASL, rCBV DSC, and PET SUVmax were associated with tumor recurrence from post-treatment changes in patients with glioma through an univariable logistic regression. Whereas the multivariable logistic regression results showed only nCBF ASL (p = 0.008) was associated with tumor recurrence from post-treatment changes in patients with glioma with OR = 22.85, CI95%: (2.28-228.77).</p><p><strong>Conclusion: </strong>In our study, ASL was the best technique, among the other two MRI PWI and the 18F-DOPA PET/CT PET, in distinguishing disease recurrence from post-treatment changes in treated glioma.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1382-1393"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141907516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: PSMA‑positive prostatic volume prediction with deep learning based on T2‑weighted MRI. 更正:基于 T2 加权磁共振成像的深度学习预测 PSMA 阳性前列腺体积。
IF 9.7 1区 医学
Radiologia Medica Pub Date : 2024-09-01 DOI: 10.1007/s11547-024-01829-4
Riccardo Laudicella, Albert Comelli, Moritz Schwyzer, Alessandro Stefano, Ender Konukoglu, Michael Messerli, Sergio Baldari, Daniel Eberli, Irene A Burger
{"title":"Correction: PSMA‑positive prostatic volume prediction with deep learning based on T2‑weighted MRI.","authors":"Riccardo Laudicella, Albert Comelli, Moritz Schwyzer, Alessandro Stefano, Ender Konukoglu, Michael Messerli, Sergio Baldari, Daniel Eberli, Irene A Burger","doi":"10.1007/s11547-024-01829-4","DOIUrl":"10.1007/s11547-024-01829-4","url":null,"abstract":"","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":"1428"},"PeriodicalIF":9.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142047060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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