Progress in neuro-psychopharmacology最新文献_第6页

Radioimmunoassay of melatonin in rat serum 大鼠血清中褪黑素的放射免疫测定

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90039-4

Lee J. Grota , Victor Snieckus , S.Osmond De Silva , Hing W. Tsui , William R. Holloway , Alfred J. Lewy , Gregory M. Brown

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引用次数: 50

3, 4 dihydroxyphenylethyleneglycol (DHPG) formation: The major route of rat brain norepinephrine metabolism 3,4二羟基苯乙二醇(DHPG)的形成:大鼠脑去甲肾上腺素代谢的主要途径

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90041-2

Peter P. Li, Jerry J. Warsh, Damodar D. Godse

引用次数: 13

Determination of brain regional normetanephrine levels by liquid chromatography with electrochemical detection (LC-EC) 液相色谱-电化学检测(LC-EC)测定脑区去甲肾上腺素水平

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90046-1

Andrew S. Chiu , Damodar D. Godse, Jerry J. Warsh

引用次数: 4

Role of serotonergic and adrenergic systems in alcohol tolerance 血清素和肾上腺素系统在酒精耐受性中的作用

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90027-8

J.M. Khanna, H. Kalant, A.D. Lê, A.E. LeBlanc

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引用次数: 14

Neurotransmitter systems in aging and senile dementia 衰老和老年性痴呆的神经递质系统

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90025-4

Edith G. McGeer

{"title":"Neurotransmitter systems in aging and senile dementia","authors":"Edith G. McGeer","doi":"10.1016/0364-7722(81)90025-4","DOIUrl":"10.1016/0364-7722(81)90025-4","url":null,"abstract":"<div><ul><li>1.1. Reported changes in neurotransmitter systems with aging in human and animal brain are briefly reviewed. The effects of age appear to vary from region to region in brain, as well as from system to system. Considerable evidence is available that dopaminergic activity decreases with age, particularly in the striatum and nucleus accumbens; this loss may be important to age-related losses in agility and increases in the incidence and severity of tardive dyskinesia. Lesser, but still convincing, evidence indicates decreases with age in noradrenergic, GABAergic and cholinergic systems, with the most marked effects being found, respectively, in the hypothalamus, thalamus and cortex-hippocampus. The cortical and hippocampal losses in cholinergic activity are markedly accentuated in senile dementia of the Alzheimer type and are probably related to memory defects in aging and dementia.</li><li>2.2. Serotonin and met-enkephalin systems in the hypothalamus are probably relatively unchanged by age and little or no information is available on numerous other putative transmitters.</li><li>3.3. Brief consideration is also given to age-related changes in the density of specific binding sites, possible reasons for lack of therapeutic effect of choline analogs in senile dementia, and the question of whether cell death, loss of nerve endings and/or decreased neuronal vitality underlie the deficits found.</li></ul></div>","PeriodicalId":20801,"journal":{"name":"Progress in neuro-psychopharmacology","volume":"5 5","pages":"Pages 435-445"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0364-7722(81)90025-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17189418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 61

Abstracts Presented at the Canadian College of Neuro-psychopharmacology Fourth Annual Meeting University of Toronto, Clark Institute of Psychiatry Toronto, April 23 – 25 1981 1981年4月23日至25日，多伦多大学克拉克精神病学研究所加拿大神经精神药理学学院第四届年会上发表

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90082-5

引用次数: 0

Antidepressant action of lithium: Proposed mechanism based upon behavioral analysis in the mouse 锂的抗抑郁作用:基于小鼠行为分析提出的机制

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90086-2

Henriette Frances, Marie-Hélène Marion, Pierre Simon

引用次数: 2

Effect of morphine on rectal temperature after acute and chronic treatment in the rat 吗啡对大鼠急慢性治疗后直肠温度的影响

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90087-4

Robert Numan , Harbans Lal

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引用次数: 22

The effects of acute and chronic administration of β-phenylethylamine on food intake and body weight in rats 急性和慢性给药β-苯乙胺对大鼠食物摄入和体重的影响

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-05-07 DOI: 10.1016/0364-7722(81)90093-X

Colin T. Dourish, Alan A. Boulton

引用次数: 34

Dextro-propranolol in schizophrenia 右心得安治疗精神分裂症

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 Epub Date: 2004-07-14 DOI: 10.1016/0364-7722(81)90106-5

Steven R Hirsch , Rahul Manchanda , Malcolm P.I Weller

引用次数: 12