Psycho‐Oncology最新文献

{"title":"Comparative and Dose-Response Effects of Exercise Modalities on Sleep Quality in Individuals With Breast Cancer: A Bayesian Network Meta-Analysis.","authors":"Yongqing Guo, Xianyang Xin, Xiupeng Li, Pengfei Wang, Zhihao Qi, Qinzheng Liu, Mingyue Jiao, Zhide Liang, Qinlong Liu","doi":"10.1002/pon.70553","DOIUrl":"10.1002/pon.70553","url":null,"abstract":"<p><strong>Objective: </strong>To compare the effects of exercise modalities on sleep quality in individuals with breast cancer, and to examine dose-response associations between exercise dose and sleep improvement.</p><p><strong>Methods: </strong>PubMed, Web of Science, Embase, the Cochrane Library, and EBSCO were searched from inception to March 2026. Risk of bias was assessed using RoB 2. Bayesian multilevel network meta-analysis compared exercise modalities against active controls. Meta-regression and nonlinear dose-response analyses explored effect modifiers and dose-response patterns.</p><p><strong>Results: </strong>Thirty-nine randomized controlled trials involving 4066 participants were included. Compared with active controls, Tai Chi/Qigong showed the largest sleep benefit (Hedges' g = -0.45, 95% CrI: -0.86 to -0.04), followed by yoga and combined exercise (COM; both g = -0.30). Aerobic exercise suggested possible benefit but with uncertainty, whereas resistance training, dance, and stretching showed no clear advantage. Dose-response analyses suggested greater benefits around potentially beneficial moderate-dose ranges, with exploratory estimated values of approximately 4.5 METs, 281.3 MET·min/session, and 910 MET·min/week. Higher baseline Pittsburgh Sleep Quality Index scores were associated with greater sleep improvement.</p><p><strong>Conclusions: </strong>Tai Chi/Qigong, yoga, and COM may be promising exercise modalities for improving sleep quality in this population. Exercise-related sleep benefits may occur within a moderate dose window. Given the very low certainty of evidence and limited head-to-head comparisons, these findings should be interpreted cautiously and confirmed by high-quality randomized controlled trials.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70553"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13374674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148472228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Mental Health Screening Tools for Cancer Patients, and Their Caregivers: An Umbrella Review\".","authors":"","doi":"10.1002/pon.70530","DOIUrl":"10.1002/pon.70530","url":null,"abstract":"","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70530"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13484139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148339937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Experiences of Cancer Patients Following an Internet-Based Cognitive Behavioral Therapy for Insomnia With Professional Phone Guidance: The Sleep-4-All-2.0 Study.","authors":"Jonathan Journiac, Anne-Laure Sébert, Louise Zanni, Léonor Fasse, Dominique Hernot, Alexandra Monod, Cécile Charles, Jean-Bernard Le Provost, Estelle Guerdoux, Guilhem Paillard-Brunet, Josée Savard, Sarah Dauchy, Diane Boinon","doi":"10.1002/pon.70532","DOIUrl":"10.1002/pon.70532","url":null,"abstract":"<p><strong>Background: </strong>Sleep problems affect 30%-95% of cancer patients. Cognitive Behavioral Therapy for Insomnia is recognized as the most effective treatment for insomnia. However, implementing it is challenging due to a lack of time, human resources, and financial support. Internet-Based Cognitive Behavioral Therapy (ICBT-I) is appreciated by patients, but it lacks professional guidance.</p><p><strong>Aims: </strong>The Sleep-4-All-2.0 study combined a validated ICBT-I program, lasting 6-12 weeks, with up to four individual, phone-based ICBT-I psychology sessions. The current study sought to explore patients' experiences of the program, focusing on their perceptions of the professional guidance.</p><p><strong>Methods: </strong>Cancer patients from three different hospitals were interviewed. Out of their discourse, a thematic analysis was conducted.</p><p><strong>Results: </strong>48 patients were included. Three themes were constructed: (1) Coping with the program, (2) Connections at play (professionals, family, patients, sleep interactions), (3) Benefits and limits of psychological guidance. Although most participants were delighted with the program and the guidance, they encountered numerous difficulties due to personal and external issues, as well as the demands of CBT. Participants highlighted the need to be connected to other patients, supported by their families, and to receive well-informed care from healthcare professionals (HCP). The phone guidance was important for pragmatic and motivational reasons.</p><p><strong>Conclusion: </strong>In order to improve program follow-up, clinicians should work beforehand to adjust expectations and take into account the specific vulnerabilities of certain patients.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70532"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148339992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical Appointments are Associated With Same-Day Worry and Sleep Difficulties Among Cancer Survivors.","authors":"Katharine E Daniel, Amanda C Collins, Kirsten L Greene, Kelly M Shaffer, Philip I Chow","doi":"10.1002/pon.70531","DOIUrl":"10.1002/pon.70531","url":null,"abstract":"<p><strong>Background: </strong>Symptoms of anxiety, including worry and sleep, can be exacerbated by impending medical appointments. These symptoms can impact cancer survivors' ability to prepare for or process information during their appointments.</p><p><strong>Aims: </strong>The current study aimed to investigate how worry and sleep change during days or weeks prior to a medical appointment in individuals receiving active treatment for cancer or those in follow-up care. In addition, we examined how coping strategies are associated with fluctuations in worry and sleep around medical appointments.</p><p><strong>Methods: </strong>Participants with a history of cancer (N = 259, age M = 49, 90.7% female, 84.2% non-Hispanic white) completed a baseline assessment, ecological momentary assessments, and weekly surveys for 5 weeks. We conducted a series of multi-level models to examine how appointment day, treatment status, and coping strategies, along with their interactions, predict daily worry and self-reported sleep.</p><p><strong>Results: </strong>On average, participants reported greater worry on days with (vs. without) a medical appointment, regardless of their coping strategies and treatment status. In addition, greater use of emotion suppression was associated with worse self-reported sleep quality the night before an appointment. Reduced self-reported sleep duration was also associated with greater use of suppression, but only among those in active treatment.</p><p><strong>Conclusions: </strong>Medical appointments are associated with worry and self-reported sleep difficulties among cancer survivors, but effects on sleep depend on stage in treatment and/or habitual use of suppression. Cancer survivors may benefit from strategies to manage appointment-related anxiety, with an emphasis on targeted interventions to improve putatively adaptive coping strategies.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70531"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13310531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"As Long as I Live, My Sweet Boy You'll Be:\" Parents' Continuing Bonds in Early Bereavement.","authors":"Ben Herold, Christy M Lucas, Sarah B McCarthy, Jennifer M Snaman","doi":"10.1002/pon.70556","DOIUrl":"10.1002/pon.70556","url":null,"abstract":"<p><strong>Background: </strong>Bereaved parents seek ways to maintain connections with their deceased child throughout their lifelong grief. These continuing bonds may bolster parental social functioning, yet limited research has explored continuing bonds early in bereavement.</p><p><strong>Aims: </strong>To explore how parents maintain connection with their child within the first 2 years following death.</p><p><strong>Methods: </strong>Parents of children who died from cancer 6-24 months prior completed the 11-item Continuing Bonds Scale (CBS) and an open-ended question querying ongoing connections. CBS scores ranged from 11 to 55, with higher scores indicating stronger continuing bonds. We examined associations between CBS scores and parent/child factors and qualitatively analyzed free-text responses.</p><p><strong>Results: </strong>Among 128 parents who completed the CBS, 103 (80%) provided free-text responses. Most respondents identified as non-Hispanic (91%), white (81%), and female (63%). Surveys were completed a mean of 15 (range 8-26) months after the child's death. The mean CBS score was 45.6 (SD = 7.8), indicating strong continuing bonds. Mothers reported higher scores than fathers (mean 46.9, SD = 7.2 vs. 43.4 SD = 8.2, p = 0.023). Free-text responses fell into five thematic domains: (1) physical connection; (2) symbolic and spiritual connection; (3) emotional and relational connection; (4) continuing shared experiences; and (5) legacy and action. Most parents described ongoing connections across multiple domains.</p><p><strong>Conclusion: </strong>Bereaved parents exhibit strong and complex continuing bonds in early bereavement. Improved understanding of these continuing bonds may help to develop supportive interventions focused on strengthening bonds that facilitate grief integration and potentially mitigate long-term psychosocial sequelae.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70556"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13409192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148607082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Image Following Ostomy Surgery for Cancer: A Systematic Review.","authors":"Emma Hanlon, Lucy Hayden, Johannes Karl, Simon Dunne","doi":"10.1002/pon.70538","DOIUrl":"10.1002/pon.70538","url":null,"abstract":"<p><strong>Background: </strong>Ostomy surgery, often required in the treatment of colorectal, bladder, prostate and gynaecological cancers, has profound effects on body image and psychosocial well-being. While previous reviews have examined body image in colorectal cancer patients, no synthesis to date, to our knowledge, has focused on body image across cancer-related ostomy populations.</p><p><strong>Methods: </strong>A systematic review methodology was employed, following PRISMA guidelines. Four databases (PsycINFO, MEDLINE, CINAHL, and Web of Science) were systematically searched for peer-reviewed, quantitative studies assessing body image in cancer survivors with ostomies. Inclusion criteria required validated body image measures and separable ostomy data. Ten studies met eligibility criteria, comprising 1454 participants.</p><p><strong>Results: </strong>Across studies, the presence of a stoma was consistently associated with poorer body image compared to non-stoma groups. Permanent stomas were linked with the greatest body image disturbance, while reversal of temporary stomas was associated with improvements. Body image was associated with psychosocial outcomes including quality of life, anxiety, depression, self-efficacy, and social support, and many of these psychosocial variables mediated the relationship between stoma status and psychological wellbeing. However, evidence regarding differences across cancer types was limited, and definitions and measures of body image varied considerably, with some studies relying on instruments not specifically designed for cancer populations.</p><p><strong>Conclusions: </strong>Body image distress is a significant yet under-recognised concern for cancer survivors with ostomies. Greater conceptual clarity, standardised and ostomy-sensitive measurement, and longitudinal research across cancer diagnoses are needed.</p><p><strong>Implications for cancer survivors: </strong>More refined ostomy-sensitive measurement, routine assessment of body image concerns and access to tailored psychosocial interventions may improve body image and related outcomes for cancer survivors with ostomies.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70538"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13332680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148387968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mixed Methods Trajectory Analysis of Daily Educational and Social Experiences of Youth With Cancer From Diagnosis to Early Survivorship.","authors":"Emily L Moscato, Qing Duan, Shabeeb Hammad, Michelle A Siddiqui, Ian Stabl, Daniel Skinner, Megan P Elam, Mary Kay Irwin","doi":"10.1002/pon.70543","DOIUrl":"10.1002/pon.70543","url":null,"abstract":"<p><strong>Background: </strong>Youth with cancer may face acute and long-term academic and social challenges. Most existing research has relied on cross-sectional or single-informant methods to describe these challenges. This longitudinal, convergent mixed-methods study aimed to characterize academic and social challenges faced by youth with cancer, from the perspective of youth, caregivers, and educators-from onset of diagnosis into survivorship.</p><p><strong>Methods: </strong>Seventy-five triads of youth (M_age = 9.07 years, SD_age = 3.15 years, range 5-14 years), caregivers, and educators completed a Perceptions Questionnaire across three timepoints: at diagnosis (T1), mid-treatment (T2), and one-year post-treatment (T3). Higher ratings indicated greater perceived impact on school attendance, medical issues, teacher knowledge, social issues, and academic performance. A subset of fifteen triads also participated in semi-structured Waking Day interviews at parallel timepoints. A convergent analysis involving mixed modeling using questionnaire data and trajectory analysis by three qualitative coders characterized patterns of change and compared diagnostic groups.</p><p><strong>Results: </strong>Significant disruptions were observed at T1, which mostly improved over time (p < 0.001). Academic and social concerns persisted for those with brain tumors or who were female. Caregivers and educators consistently expressed concern about long-term academic impact, while youth showed decreasing concern compared to caregivers and educators (b = 0.61, SE = 0.26, p = 0.02 and b = 0.76, SE = 0.31, p = 0.02). Qualitative responses generally suggested more difficulties than questionnaire data and provided additional context.</p><p><strong>Conclusions: </strong>Results affirm the importance of ongoing needs assessment for youth with cancer through multiple methods. Findings also may inform tailored psychosocial and educational interventions to enhance the quality of life for youth affected by cancer and their families.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70543"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13379807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148472301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The American Psychosocial Oncology Society's Psychosocial Oncology Virtual Academy: Enhancing Access to Specialized Psychosocial Oncology Care.","authors":"Sharla Wells-Di Gregorio, Brad McAlister, Karen Kayser, Amy Siston, Stacy Flowers, Cathy Donnell, George Fitchett, Tamryn F Gray, Jesse R Fann, Jessica Vanderlan, Debbie Snyder, Nicole Bates, Teresa Deshields, Sarah Baltimore, Madison Voinovich, Tanya Smit, Donald R Marks","doi":"10.1002/pon.70520","DOIUrl":"10.1002/pon.70520","url":null,"abstract":"<p><strong>Objective: </strong>By 2040, there will be 26 million cancer survivors in the United States, with approximately 40% experiencing cancer-related challenges warranting psychosocial care. Simultaneously, the US has a psychosocial workforce shortage. The American Psychosocial Oncology Society (APOS) created the Psychosocial Oncology (PSO) Virtual Academy in 2022 to expand the PSO workforce. This study provides a formative evaluation of this curriculum.</p><p><strong>Methods: </strong>The PSO Virtual Academy is a 15-session training program provided via the Trusted Provider Network (TPN), a continuing education platform. The majority of registrants come from West Virginia (n = 28) and California (n = 21), states in which APOS has partnered to increase access to evidence-based PSO care. After finishing each session, course participants completed a brief mixed methods survey. In this study, we examine feasibility (educational, technical, and operational), acceptability, learning effectiveness, strengths, and areas for improvement.</p><p><strong>Results: </strong>Since 2022, 262 behavioral health specialists have registered, and 147 (56%) have completed the certificate course. Eighty-four percent reported satisfaction with their overall experience with the program. Technology use was satisfactory for 76% of participants. Ninety-six percent reported learning an average amount to a great deal. Areas of strength included engaging faculty and inclusion of clinical discussions. Areas for improvement included providing slide handouts, greater focus on clinical interventions, and assessment tools.</p><p><strong>Conclusions: </strong>The PSO Virtual Academy 1.0 has provided satisfactory and useful training to over 147 behavioral health professionals, helping APOS to expand the PSO workforce in several mental health shortage areas. Work is underway to complete a summative evaluation and develop version 2.0, which will incorporate a briefer, standardized format for didactic content, in-person skills-based training components, and a case-based community of practice.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70520"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148472404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Associations Between Inflammatory Markers at 12-Months and Three Core Symptoms of Depression at 12- and 24-Months After Colorectal Cancer Diagnosis: Results From the Population-Based PROFILES Registry.","authors":"Chris Hinnen, Floortje Mols, Dounya Schoormans","doi":"10.1002/pon.70555","DOIUrl":"10.1002/pon.70555","url":null,"abstract":"<p><strong>Purpose: </strong>Depression is a heterogeneous construct comprising distinct symptom domains, including motivational anhedonia, consummatory anhedonia, and negative affect, commonly experienced by colorectal cancer (CRC) survivors. Inflammation has been implicated in depression, its association with specific depressive symptom domains in CRC survivors remains insufficiently characterized.</p><p><strong>Methods: </strong>CRC patients (n = 497) completed questionnaires assessing depressive symptoms 12- and 24-months post-diagnosis: motivational anhedonia (Multidimensional Fatigue Inventory), consummatory anhedonia (Hospital Anxiety and Depression Scale-depression), and negative affect (EORTC QLQ-C30, emotional functioning). Associations between 11 inflammatory markers (CRP, IL-1α, IL-1β, IL-6, IL-8, IL-10, IL-17A, IL-22, IFN-γ, sTNFRI, and sTNFRII) at 12-months and depressive symptoms at 12- and 24-months were examined using linear mixed models.</p><p><strong>Results: </strong>IL-1β (Est = 0.089, p = 0.003) and IFN-γ (Est = 0.067, p = 0.001) were associated with more consummatory anhedonia symptoms across time, and a small sTNFRI × time interaction was found (Est = 0.000, p = 0.007). Negative affect was associated with IL-1β (Est = -0.496, p < 0.001), IFN-γ (Est = -0.354, p < 0.001), and sTNFRI (Est = -0.003, p < 0.001). A significant IL-1α × time interaction was observed (Est = 0.250, p = 0.038) for motivational anhedonia.</p><p><strong>Conclusions: </strong>Most consistently IL-1β, IFN-γ, and sTNFRI was associated with greater consummatory anhedonia and more negative affect in CRC survivors. In addition, inflammatory correlates (IL-1α and sTNFRI) of motivational anhedonia and consummatory anhedonia changed over time. These findings suggest that selected inflammatory pathways may contribute to specific depressive symptom domains during colorectal cancer survivorship. Given the exploratory nature of the analyses, replication in independent cohorts is required before clinical implications can be drawn.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70555"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13379931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148497964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain Experiences During Early Treatment for Pediatric Acute Lymphoblastic Leukemia: A Qualitative Study.","authors":"Kimberly L Klages, Cecelia I Nelson, Julia K Herriott, Robin E Norris, Meghan E McGrady, Susmita Kashikar-Zuck, Ahna L H Pai","doi":"10.1002/pon.70550","DOIUrl":"10.1002/pon.70550","url":null,"abstract":"<p><strong>Background: </strong>Pain is a common and distressing symptom for pediatric patients with acute lymphoblastic leukemia (ALL), arising from the disease itself, its treatment, and associated medical procedures. The early phase of treatment is particularly challenging, as children experience multiple, rapidly evolving sources of pain. Despite its prevalence, pain during this period remains poorly characterized. This study qualitatively examined pain experiences among children with ALL during induction and early consolidation.</p><p><strong>Methods: </strong>Twenty caregivers of children with ALL (ages 2-17) and eight patients (ages 8-17) participated in two semi-structured interviews capturing pain experiences across early treatment. Interviews were audio-recorded, transcribed, and analyzed using thematic analysis.</p><p><strong>Results: </strong>Eight themes described key dimensions of the pain experience: Sources of Pain, Pain Characteristics, Pain-Related Symptoms, Factors Influencing Pain, Pain Impact, Pain Expression, Pain Management Tools, and Barriers to Pain Management. These themes reflected the evolving, multidimensional nature of pain during early treatment.</p><p><strong>Conclusions: </strong>Children with ALL experience substantial and multifaceted pain early in their cancer trajectory. Findings underscore the need for early, developmentally informed, and family-centered approaches to pain assessment and management that address the complex and evolving nature of pain during initial treatment.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70550"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13366143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148437891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}