Psycho‐Oncology最新文献

{"title":"Intervention-Related Changes in Coping Ability Drives Improvements in Mood and Quality of Life for Patients Taking Adjuvant Endocrine Therapy.","authors":"Leah E Walsh, Laura Dunderdale, Nora Horick, Jennifer S Temel, Joseph A Greer, Jamie M Jacobs","doi":"10.1002/pon.70049","DOIUrl":"10.1002/pon.70049","url":null,"abstract":"<p><strong>Objective: </strong>A recent randomized trial of a group psychosocial telehealth intervention (STRIDE) improved anxiety, depression, quality of life (QOL), symptom distress, coping, and self-efficacy to manage symptoms related to taking adjuvant endocrine therapy (AET) in women with non-metastatic hormone receptor-positive breast cancer. This study examined whether changes in coping and self-efficacy mediated intervention effects on anxiety, depression, QOL, and symptom distress.</p><p><strong>Method: </strong>Women (N = 100) were recruited between 10/2019-06/2021 from Massachusetts General Hospital and were randomized to STRIDE or to the medication monitoring control group. Participants completed self-report measures of anxiety and depression (Hospital Anxiety and Depression Scale), QOL (Functional Assessment of Cancer Therapy-Breast Cancer scale), symptom distress (Breast Cancer Prevention Trial Symptom Scale), coping (Measure of Current Status-Part A), and self-efficacy (Self Efficacy for Managing AET Symptoms) at baseline and 24-week follow-up. Mediated regression models tested whether changes in coping ability and self-efficacy mediated the intervention effects on anxiety, depression, QOL, and symptom distress, controlling for key variables.</p><p><strong>Results: </strong>Improvements in coping across the 24-week study period mediated the effect of STRIDE on anxiety symptoms (indirect effect, B = -0.61, SE = 0.28, 95% CI: -1.28, -0.17), depressive symptoms (indirect effect, B = -0.50, SE = 0.21, 95% CI: -0.97, -0.15), and QOL (indirect effect, B = 3.80, SE = 1.25, 95% CI: 1.54, 6.49), but not symptom distress. Changes in self-efficacy did not mediate improvements in any of the proposed outcomes.</p><p><strong>Conclusion: </strong>Coping is an essential component of a brief group psychosocial intervention that drives improvements in mood and QOL for women with non-metastatic hormone receptor-positive breast cancer taking AET.</p><p><strong>Clinical trial registration: </strong>NCT03837496.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70049"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-Reported Worst-Case Scenarios in Advanced Cancer: Presence, Contents, and Predictors.","authors":"Joanna J Arch, Mackenzie H Kirk, Lauren B Finkelstein","doi":"10.1002/pon.70039","DOIUrl":"https://doi.org/10.1002/pon.70039","url":null,"abstract":"<p><strong>Background: </strong>Advancements in precision oncology have led to a growing community of adults with advanced cancer who live longer but face prognostic uncertainty, with corresponding fears of the future. Their worst future fears related to cancer remain understudied, hindering support efforts.</p><p><strong>Aims: </strong>This study aimed to characterize the presence, content, and predictors of imagined future worst-case scenarios related to cancer (WCS) among distressed adults with advanced cancer.</p><p><strong>Methods: </strong>Two hundred fifteen distressed adults with advanced solid tumor cancer (mixed type) responded to survey questions regarding the presence (Yes/No) of a WCS related to cancer and if yes, to briefly describe it. Mixed methods were used to assess WCS prevalence, thematic content, and sociodemographic, psychological, and medical predictors.</p><p><strong>Results: </strong>Two thirds (66.5%) of advanced cancer survivors endorsed having a WCS. Content reflected four major themes of Death (52.2%), Suffering and Deterioration (47.1%), Cancer Progression and Future Uncertainty (28.7%), and Concern about Family (18.4%). WCS often contained more than one major theme, further distinguished by additional themes and sub-themes that revealed distinct fears. Higher anxiety and lower life meaning/peace predicted the presence of a WCS whereas sociodemographic characteristics, depression, time since diagnosis, and physical symptom burden did not. Younger age and living with children predicted a WCS focused on loved ones.</p><p><strong>Conclusions: </strong>WCS are prevalent and diverse in content among distressed adults with advanced cancer. Assessing WCS offers a quick and straightforward way to solicit advanced cancer survivors' most intense fears about the future with cancer, thereby facilitating patient-provider communication and support efforts.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70039"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coming out of the Integrative Oncology Comfort Zone: Addressing Healthcare Providers' Wartime-Related Concerns.","authors":"Shir Eliyas, Orit Gressel, Eran Ben-Arye, Jan Vagedes, Noah Samuels, Sameer Kassem","doi":"10.1002/pon.70042","DOIUrl":"10.1002/pon.70042","url":null,"abstract":"<p><strong>Study objective: </strong>To assess the impact of a personalized integrative medicine (IM) intervention on healthcare providers (HCPs) expressing war-related emotional/spiritual and physical concerns.</p><p><strong>Methods: </strong>Physicians, nurses, para-medical and other HCPs from 5 hospital departments in northern Israel underwent IM treatments provided by IM-trained practitioners working in integrative oncology (IO) care settings. The two main HCP-reported concerns were scored (from 0 to 6) before and following the intervention using the Measure Yourself Concerns and Wellbeing questionnaire. Post-intervention narratives were examined for emotional/spiritual keywords (ESKs).</p><p><strong>Results: </strong>Of 190 participating HCPs, 121 (63.7%) expressed ESKs in post-treatment narratives (ESK group), with 69 not expressing ESKs (nESK group). Both groups had similar demographic and professional backgrounds, and reported improved measure yourself concerns and well-being (MYCAW) QoL-related concerns immediately post-intervention. However, between-group analysis found significantly greater improvement in the ESK group for the first (p < 0.001) and second (p = 0.01) MYCAW concerns, as well as emotional/spiritual concerns (p < 0.001). Pain-related concerns improved similarly in both groups, with improved scores continuing to 24-h post-treatment.</p><p><strong>Conclusions: </strong>HCPs with war-related emotional/spiritual and physical QoL-related concerns showed significant improvement following the IM intervention. This was more significant among those reporting ESKs for their two major and emotional/spiritual concerns, with pain scores improving similarly in both groups. Future research needs to explore specific and non-specific effects of IM intervention provided by IO practitioners working outside their \"comfort zone\", fostering collaboration between IM and mental health providers to address HCP wellbeing and resilience during a time of national crisis.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70042"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Value of Individual Behavioral Risk Factors for New Mood-Related Psychiatric Disorder After Diagnosis of Cancer.","authors":"Seiichi Villalona, Carlos Chavez Perez, E Paul Wileyto, Samuel Takvorian, Peter Gabriel, Abigail Doucette, Daniel Blumenthal, Robert Schnoll","doi":"10.1002/pon.70046","DOIUrl":"10.1002/pon.70046","url":null,"abstract":"<p><strong>Objective: </strong>The diagnosis of a mood-related psychiatric disorder (MRPD) among patients with cancer has been associated with decreased quality of life and lower cancer survival. This study aimed to understand the risk of a new MRPD after cancer diagnosis by individual risk behaviors, with a specific focus on tobacco use and the presence of a human papillomavirus (HPV)-associated cancer.</p><p><strong>Methods: </strong>Single-center retrospective cohort study of 11,712 patients diagnosed with cancer between 2009 and 2020. We identified predictors of a new MRPD after cancer diagnosis using a time-to-event analysis and Cox proportional hazards model including demographics, disease characteristics, and tobacco use and HPV-associated tumors.</p><p><strong>Results: </strong>Univariate analyses revealed lower hazard ratios (HRs) of a new MRPD among individuals that identified as Asian/Pacific Islanders and among the older age groups (> 51 years). Univariate analyses additionally demonstrated higher HRs of MRPD among females; sexual minorities; former and current smokers; individuals with HPV-associated cancers; and individuals diagnosed at later stages. These relationships were observed in the multivariate model when adjusting for covariates. Shorter time-to-MRPD was observed when stratifying by individual behavioral risk factors, with active smokers and individuals with an HPV-associated cancer being at the highest risk.</p><p><strong>Conclusions: </strong>Individual behavioral risk factors increase risk of new MRPD after being diagnosed with cancer. These findings build on past studies by linking tobacco use and HPV-associated cancers with MRPD risk in oncology and can be used to identify patients at risk of developing new MRPDs post-cancer diagnosis and engaging them in treatment.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70046"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breadth and Depth of Patient and Caregiver Supportive Services in Community Oncology (WF-1803CD).","authors":"Laurie E McLouth, Katherine R Sterba, Anna C Snavely, Kathryn E Weaver, Emily V Dressler, Erin E Kent, Christian S Adonizio, Suzanne C Danhauer, Charles Kuzma, Timothy Moore, Chandylen L Nightingale","doi":"10.1002/pon.70034","DOIUrl":"10.1002/pon.70034","url":null,"abstract":"<p><strong>Background: </strong>Providing supportive services to patients and their caregivers is essential to quality cancer care, yet the depth, availability, and infrastructure underlying these services remains unknown in community practice. We assessed these factors among practices within the National Cancer Institute Community Oncology Research Program (NCORP) to guide priorities for comprehensive supportive service(s) development and inform implementation of evidence-based interventions in clinical practice.</p><p><strong>Methods: </strong>Supportive care leaders at NCORP practices completed online surveys regarding availability of services to patients and caregivers within seven domains, service infrastructure (e.g., staffing, technology), and implementation recommendations for caregiver-specific services. Primary outcomes were the proportion of practices offering at least one service in each domain to both populations and the proportion offering caregiver training/education.</p><p><strong>Results: </strong>Of the 103 participating practice groups, only 15.5% offered at least one service in each domain to both populations; 21.4% offered caregiver training/education. Psychological (83.5%) and spiritual/religious (75.7%) services were most widely available to both; health promotion (28.2%) services were least available to both. Services offered were largely available on-site with dedicated staff; caregiver-specific services were nearly always off-site and typically self-pay. Practices most often used the patient health portal to communicate with patients and caregivers (54.4%). Only 28.9% provided bilingual staff for services. Social workers (35.7%) and navigators (34.7%) were recommended to support caregiver services.</p><p><strong>Conclusions: </strong>To meet national recommendations for supportive service provision, practices should invest in caregiver education/training programs, expand health promotion programs, and increase interpretation services. Future interventions should leverage existing resources (e.g., recommended staff, patient portal).</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70034"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation on the Changes of Perioperative Psychological State of Young Patients With Early Breast Cancer.","authors":"Yinpeng Ren, Xiangyu Wang, Wenya Peng, Kairong Yang, Xiangyi Kong, Jiang Jiang, Jing Wang","doi":"10.1002/pon.70027","DOIUrl":"10.1002/pon.70027","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to explore the variations and dynamics in the mental states of young patients with early breast cancer across different perioperative periods and to analyse how different surgical methods impact these patients' psychological well-being.</p><p><strong>Methods: </strong>A prospective observational study was conducted on young patients with early breast cancer who underwent surgery from March 2021 to March 2022. Mental status questionnaires were administered at four key time points: preoperatively, 1 month, 6 months and 1 year postoperatively. The collected data were statistically analysed to discern the psychological shifts in these patients throughout the perioperative timeline. The patients were categorized into either the breast-conserving or mastectomy group based on their surgical procedure, and their mental state scores during each phase were analysed to investigate the effects of different surgical methods on their psychological health.</p><p><strong>Results: </strong>During the study period, 149 young patients with early breast cancer completed the four-phase questionnaire. Statistically significant differences were observed in self-evaluation, self-esteem, physiological state, fear of death, economic stress, negative emotion, and anxiety and depression among these patients across different periods. The baseline data revealed differences in marital status, place of residence and prior tumour history between the two surgical groups. Significant differences in self-evaluation, depression, self-esteem and positive emotions were found between the breast-conserving group and mastectomy groups.</p><p><strong>Conclusion: </strong>Breast cancer presents significant physical and psychological challenges from diagnosis through treatment. Our findings indicate that young patients with early breast cancer experience varying degrees of psychological distress during the entire perioperative period, influencing their surgical choices and postoperative recovery. This study found that the psychological state of patients undergoing breast-conserving surgery is more favourable compared with that of patients who received mastectomies, particularly in terms of self-assessment, self-esteem, positive affect and depression levels.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70027"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Shame and Stigma, and Other Psychosocial Predictors of Psychological Distress Among Cancer Patients in Malaysia.","authors":"Hui Ting Eyu, Nik Ruzyanei Nik Jaafar, Mohammad Farris Iman Leong Abdullah, Hajar Mohd Salleh Salimi, Mohd Razif Mohamad Yunus, Fuad Ismail, Nur Fa'izah Ab Muin, Noor Syazwani Abdul Aziz","doi":"10.1002/pon.70020","DOIUrl":"https://doi.org/10.1002/pon.70020","url":null,"abstract":"<p><strong>Background: </strong>Patients' sociodemographic factors, clinical characteristics, distress factors, perceived shame and stigma may give rise to psychological distress in cancer patients that bring about further psychosocial impact.</p><p><strong>Aims: </strong>(1) to determine the degrees of shame and stigma towards cancer and psychological distress among cancer patients in Malaysia and (2) to examine the clinical and psychosocial predictors of psychological distress.</p><p><strong>Methods: </strong>This cross-sectional study recruited a total of 217 cancer patients. The participants were administered the sociodemographic and clinical characteristics questionnaires, the Malay version of the Shame and Stigma Scale (SSS-M) to assess for the degree of cancer shame and stigma, and the Malay version of the Distress Thermometer and Problem List to assess for presence of psychological distress and identify its sources.</p><p><strong>Results: </strong>There was a significant level of shame and stigma among cancer patients with the total mean SSS-M score of 12.08 (SD = 6.09). Anger (adjusted odds ratio [AOR] = 11.97, 95% confidence interval [CI] = 2.96-86.8, p = 0.001), loss of interest or enjoyment (AOR = 14.84, 95% CI = 2.93-75.20, p = 0.001), loneliness (AOR = 8.10, 95% CI = 1.13-58.02, p = 0.001), feeling of worthlessness or being a burden (AOR = 6.24, 95% CI = 1.32-29.59, p = 0.021), fear (AOR = 4.52, 95% CI = 1.79-11.43, p = 0.001), pain (AOR = 4.07, 95% CI = 1.53-10.82, p = 0.005), financial constraint (AOR = 2.95, 95% CI = 1.22-7.13, p = 0.016), and having regret (AOR = 1.89, 95% CI = 1.03-3.79, p = 0.039) increased the odds of developing psychological distress.</p><p><strong>Conclusion: </strong>Treating clinicians should monitor for and provide psychosocial interventions for the biopsychosocial factors which may worsen psychological distress among cancer patients.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70020"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scanxiety and Fear of Recurrence in Young Adult Female Breast and Gynaecological Cancer Survivors: Investigating Shared Mechanisms.","authors":"Diya S Patel, Sarah N Webster, Emily J Dowling, Claudia R Knowles, Georgina Lockwood-Taylor, Daelin Coutts-Bain, Laura E Simons, Elisabeth J Diver, Joseph Chilcot, Lidia Schapira, Lauren C Heathcote","doi":"10.1002/pon.70050","DOIUrl":"10.1002/pon.70050","url":null,"abstract":"<p><strong>Background: </strong>Adolescent and young adult (AYA) females are vulnerable to psychological sequelae following cancer diagnosis and treatment. Fear of cancer recurrence (FCR) is well-documented in cancer survivors, however AYA survivors of breast and gynaecological cancers are less well-studied. Moreover, little is known about scan-related fears and anxiety ('scanxiety') in survivors of any age group.</p><p><strong>Aims: </strong>This study aimed to assess demographic, medical, and quality-of-life correlates of FCR and scanxiety in AYA female breast and gynaecological cancer survivors post-treatment. Additionally, we explored potential shared mechanisms of FCR and scanxiety, including intolerance of uncertainty, bodily threat monitoring, and perceived stress.</p><p><strong>Methods: </strong>AYA breast and gynaecological cancer survivors (N = 115) completed measures of FCR, scanxiety, intolerance of uncertainty, bodily threat monitoring, perceived stress, and quality of life. Bivariate associations and a structural equation model explored relationships between these variables.</p><p><strong>Results: </strong>Both FCR and scanxiety were prevalent, with 84% reporting clinically meaningful FCR and 38% reporting severe FCR. Higher FCR and scanxiety were both associated with poorer quality of life. FCR and scanxiety were moderately associated but not entirely overlapping. Intolerance of uncertainty, bodily threat monitoring, and perceived stress were significantly correlated with both FCR and scanxiety. The structural equation model indicated that bodily threat monitoring is a plausible intermediate variable linking intolerance of uncertainty and FCR, but not scanxiety.</p><p><strong>Conclusions: </strong>FCR and scanxiety are common in AYA survivors of breast and gynaecological cancers, with potentially distinct underlying mechanisms. Interventions targeting intolerance of uncertainty and bodily threat monitoring may reduce FCR, while further research is needed to identify therapeutic targets for scanxiety.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70050"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living a Cancer Surveillance Life: A Meta-Ethnographic Synthesis of Everyday Experiences and Ambivalences for Women Living With Hereditary Risk of Breast and/or Ovarian Cancer.","authors":"Julie Isabelle Plougmann Gislinge, Anna Byrjalsen, Klara Vinsand Naver, Helle Vibeke Clausen, Pernille Ravn, Kresten Rubeck Petersen, Karin Wadt, Ayo Wahlberg","doi":"10.1002/pon.70054","DOIUrl":"10.1002/pon.70054","url":null,"abstract":"<p><strong>Objective: </strong>Women with or at risk of hereditary breast- and ovarian cancer (HBOC) often live a surveillance-focused life from young adulthood. As they navigate a life of heightened medical vigilance, or a \"cancer surveillance life,\" we explore how women with HBOC, as well as their partners and families, experience this particular kind of living through a thorough literature review of existing qualitative research.</p><p><strong>Methods: </strong>We performed Boolean searches in PubMed, EMBASE, EBSCOhost, PSYCHinfo, Scopus, and Web of Science from April-May 2022, identifying 506 relevant articles. After eliminating duplicates and quantitative studies, we systematically analyzed 53 articles. Articles examining all aspects of living with HBOC were eligible for inclusion. Following quality assessment by a verified appraisal tool, 28 articles were included in this review. We undertook an \"a-lines-of-argument synthesis,\" and identified key similarities across studies to highlight generalizable aspects of living with HBOC.</p><p><strong>Results: </strong>We discovered five central themes which capture the ambivalences experienced by women living with HBOC: (1) an unresolved balancing act regarding genetic testing (2) burdens of relaying genetic information within the family (3) experienced risk discrepancies (4) preservation of the self and: (5) unsettled reproductive feelings.</p><p><strong>Conclusions: </strong>Living with HBOC is filled with ambivalences, which are critical for decision making concerning disclosing risks to family members and children, choosing between risk-reducing surgeries or surveillance, and family planning. Healthcare professionals should be aware of these findings when counseling women and families with HBOC to provide the best support possible in navigating their unique kind of living.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70054"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Web-Based Acceptance and Commitment Therapy on Health-Related Outcomes Among Patients With Lung Cancer: A Feasibility Randomized Controlled Trial.","authors":"Yalin Zhang, Chunhua Liu, Xiaoli Chen, Yun Zhang, Yunhuan Li, Xiaolin Hu","doi":"10.1002/pon.70045","DOIUrl":"10.1002/pon.70045","url":null,"abstract":"<p><strong>Objective: </strong>To identify the feasibility, acceptability, and effectiveness of web-based acceptance and commitment therapy (ACT) on health-related outcomes in patients with lung cancer.</p><p><strong>Methods: </strong>A feasibility, prospective, parallel, individual-based, assessor-blinded randomized controlled trial was designed. This study was conducted at a third-level hospital in Sichuan Province, China. A total of 101 participants were enrolled and randomly assigned to usual care group or 7-weekly web-based acceptance and commitment therapy group. The primary outcome was feasibility and acceptability of the intervention, and the secondary outcomes including quality of life, psychological flexibility, anxiety, depression, fatigue, and sleep disturbance. Generalized estimating equations were used to evaluate the group differences. All analyses followed the principle of intention-to-treat.</p><p><strong>Results: </strong>Web-based ACT presented good feasibility and acceptability in this study, with an attrition rate of 13.86%, a median compliance rate of 71.43%, and a satisfaction rate of 65.9%. Compared with control group, participants in intervention group reported statistically significant increases in quality of life (MD = 15.10, 95% CI: [10.09, 20.11], d = 0.37), psychological flexibility (MD = -8.42, 95% CI: [-10.81, -6.03], d = -1.47), anxiety (MD = -1.27, 95% CI: [-2.50, -0.05], d = -0.44), depression (MD = -2.11, 95% CI: [-3.28, -0.95], d = -0.76), and sleep disturbance (MD = -1.85, 95% CI: [-3.10, -0.59], d = 0.13) at postintervention, however, the improvement in fatigue was not statistically significant (MD = -2.02, 95% CI: [-9.02, 4.98], d = -0.12).</p><p><strong>Conclusions: </strong>Web-based ACT was an approach with good feasibility and acceptability, and it could effectively improve quality of life, psychological flexibility, anxiety, depression, and sleep disturbance in patients with lung cancer. In order to achieve better results, there is a need to design a more tailored intervention plan and a more operational platform.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 12","pages":"e70045"},"PeriodicalIF":3.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}