Psycho‐Oncology最新文献

{"title":"Experience and Coping Strategies of Endocrine Therapy-Related Symptoms in Breast Cancer Patients: A Systematic Review and Qualitative Meta-Synthesis.","authors":"Lin He, Min Wen, Bo Tao, Shanwen Sun, Hao Huang, Xiaofeng Wang, Hui Xu","doi":"10.1002/pon.70198","DOIUrl":"10.1002/pon.70198","url":null,"abstract":"<p><strong>Objective: </strong>Endocrine therapy is an essential treatment to improve disease-free and overall survival in patients with hormone receptor-positive breast cancer. However, symptoms associated with endocrine therapy severely affect patients' quality of life and medication adherence. To inform symptom management strategies, this study systematically reviews research on patients' symptom experiences and coping strategies during endocrine therapy.</p><p><strong>Methods: </strong>This study conducted a thematic synthesis of qualitative research, including patients' experiences with endocrine therapy-related symptoms and the coping strategies they employ. Systematic searches were conducted in nine databases, including six English-language databases (PsycINFO, PubMed, CINAHL, Cochrane Library, Embase, and Web of Science) and three Chinese-language databases (SinoMed, CNKI, and Weipu), with searches covering the period from database inception to May 2024. The PICoS (Population, Interest of phenomena, Context, Study design) search strategy was applied to include the required qualitative studies.</p><p><strong>Results: </strong>A total of 1758 studies were screened, and 19 qualitative studies were ultimately included, comprising 584 female patients receiving endocrine therapy. Identified five main themes: (1) antecedent factors influence symptom perception and adaptation; (2) outcomes of symptom experiences; (3) the complexity and diversity of symptoms; (4) selection of coping strategies; (5) symptom management needs. Reveals the impact of antecedent factors on symptom perception and adaptation, provides recommendations for managing endocrine therapy-related symptoms, and indicate the clinical significance and limitations of the research.</p><p><strong>Conclusions: </strong>Findings indicate that information accessibility and individual differences influence symptom perception, while physiological changes, experiences, psychological states, and information affect symptom adaptation. After symptom onset, patients often face distress and daily life/work limitations. A major challenge in symptom management is the lack of a systematic approach that accounts for symptom complexity and dynamics. Additionally, patients' informational needs are unmet, and professional support is lacking.</p><p><strong>Trial registration: </strong>This systematic review has been registered on PROSPERO (CRD:42023444435).</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70198"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Providing Outpatient Oncology Mental Health Support: Understanding Staff Perspectives.","authors":"Elizabeth Matthews, Kate Webber, Joshua F Wiley, Catriona Parker","doi":"10.1002/pon.70206","DOIUrl":"10.1002/pon.70206","url":null,"abstract":"<p><strong>Objective: </strong>Mental health challenges are common in individuals with cancer, but accessing support remains a gap, particularly in outpatient oncology. Real-world factors influencing staff's ability to integrate mental health assessment and support into workflows are unclear. We aimed to (1) identify and explore factors influencing the assessment and management of mental health in outpatient oncology and (2) identify factors that influence normalising support for mental health during cancer treatment.</p><p><strong>Methods: </strong>Through an exploratory qualitative approach, data was collected via focus groups with oncology healthcare professionals at a major metropolitan hospital. Reflexive thematic analysis revealed seven themes.</p><p><strong>Results: </strong>Staff recognised the critical need for mental health support during treatment. However, staff participation in mental health assessment and referral processes was impeded by feelings of futility due to the lack of available oncology-specific services. Staff reported insufficient resources and time constraints, and reliance on experiential knowledge rather than the preferred support from clinicians with mental health training. Staff highlighted inequities in access to mental health support which exacerbate disparities in care provision. Staff reported that a lack of role clarity and responsibilities hindered monitoring of patient mental health management and contributed to a perceived lack of accountability. Short-term initiatives such as improved documentation, creation of central referral pathways and clinical supervision for all staff were reported as desirable.</p><p><strong>Conclusions: </strong>While systemic resource constraints were acknowledged, oncology staff also identified several feasible, shorter-term initiatives they felt would be helpful and desirable until mental health professionals can be integrated into oncology outpatient care.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70206"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"You Can Rest Knowing That We Know What You Want\"-Longitudinal Advance Care Planning Discussions With Young Adults Receiving Hematopoietic Stem Cell Transplantation.","authors":"Anna Katharina Vokinger, Brian Pennarola, Paige Kube, Devon Ciampa, Gisela Michel, Jennifer Hendricks, Brigit Rweikiza, Sara K Silbert, Lori Wiener","doi":"10.1002/pon.70189","DOIUrl":"10.1002/pon.70189","url":null,"abstract":"<p><strong>Objective: </strong>Young adults (YAs) undergoing hematopoietic stem cell transplantation (HSCT) often face significant transplant-related morbidity and mortality. Advance care planning (ACP) discussions can provide YAs with the opportunity to address treatment goals and care preferences with their family members and healthcare team. However, such discussions often do not occur until YAs are critically ill or at the end of life. This pilot study aimed to examine the usefulness of a series of planned ACP discussions during transplantation and their impact on dyadic (patient-caregiver) relationships.</p><p><strong>Methods: </strong>Qualitative, semi-structured interviews were conducted with YAs, aged 18-39 years, and caregivers following completion of three ACP conversations, one of which used the Voicing My CHOiCES communication guide. Data were analyzed using a reflexive thematic approach.</p><p><strong>Results: </strong>Thirty-two interviews were conducted with 19 YAs and 13 caregivers of 21 YAs undergoing HSCT. Two main themes emerged: navigating uncertainty while facing potential mortality and reducing decisional regret. Having ACP conversations helped YAs communicate with their caregivers, often for the first time, about their preferences for care if they became seriously ill. This improved communication also often led to a sense of empowerment in knowing one another's preferences. Enhanced communication was reported to strengthen dyadic relationships.</p><p><strong>Conclusion: </strong>Age-appropriate ACP conversations allowed YAs to express their preferences for care and provided an opportunity to address possible discrepancies with their caregivers. Such conversations can help to decrease stress, empower YAs and their caregivers, and potentially reduce decisional regret through a shared understanding of the YA's voice.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70189"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12159713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Death Risk Perception and Hospice Care Decisions in Advanced Cancer: A Psychosocial Pathway Analysis of Emotional and Cognitive Mediators.","authors":"Xiaoling Zhang, Jianwei Zheng, Yuchen Lin, Huina Zou, Guojuan Chen, Huimin Xiao","doi":"10.1002/pon.70201","DOIUrl":"10.1002/pon.70201","url":null,"abstract":"<p><strong>Objectives: </strong>This study examines how death risk perception influences hospice care decision-making through psychosocial pathways in advanced cancer, with specific focus on the mediating roles of emotional distress and decision self-efficacy, and the moderating effects of social support and hospice care knowledge.</p><p><strong>Methods: </strong>A multicenter cross-sectional study with 394 advanced cancer patients was conducted between April 2023 and August 2023. Hospice care decision, death risk perception, emotional reactions, decision self-efficacy, social support, and cognition of hospice care were measured. Path analysis with bootstrapping tested sequential mediation and moderation effects. This study conformed to STROBE checklist guidelines.</p><p><strong>Results: </strong>Death risk perception directly predicted decision avoidance (b = -0.19, p < 0.001) and indirectly through emotional reactions and decision self-efficacy pathway (b = -0.29, p < 0.001). A sequential mediating effect of emotional reactions via decision self-efficacy was found, with a mediating effect size of 0.096 (p < 0.001). Moreover, social support and hospice care cognition played moderating roles in the paths from death risk perception to emotional reaction and from decision self-efficacy to hospice care decision, respectively.</p><p><strong>Conclusions: </strong>Our psycho-oncological framework reveals that enhancing death risk communication while concurrently addressing emotional reactions and strengthening social support networks may optimize advance care planning. Clinicians should integrate decision support interventions targeting these modifiable psychosocial factors.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70201"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Antidepressants on Surgical Outcomes Among Patients With Abdominal Cancer and Comorbid Depression.","authors":"Erryk S Katayama, Sidharth Iyer, Selamawit Woldesenbet, Zayed Rashid, Mujtaba Khalil, Kristen M Carpenter, Timothy M Pawlik","doi":"10.1002/pon.70210","DOIUrl":"10.1002/pon.70210","url":null,"abstract":"<p><strong>Objective: </strong>Depression is commonly linked to cancer and may negatively impact patient outcomes; however, the influence of antidepressants on surgical outcomes remains unclear. We sought to evaluate the role of antidepressants among patients with gastrointestinal cancer and comorbid depression undergoing surgical resection.</p><p><strong>Methods: </strong>Patients diagnosed with hepatobiliary, pancreatic, and colorectal cancers (2008-2019) were identified within SEER-Medicare. Comorbid depression, within 12 months before or after a cancer diagnosis, and antidepressant prescriptions were assessed. An \"ideal\" postoperative textbook outcome required no complications, prolonged stay, 90-day readmission, or 90-day mortality. Hospitalization and post-discharge expenditures were also assessed.</p><p><strong>Results: </strong>Among 32,726 cancer patients (hepatobiliary: 2313, 7%; pancreatic: 2583, 8%; colorectal: 27,830, 85%), 1731 (5.3%) had documented depression (478 treated vs. 1253 untreated with antidepressant medications). Patients were more likely to receive treatment for depression if they were female (treated: 71% vs. untreated: 68%), White (treated: 88% vs. untreated: 80%), and had lower comorbidity burden (treated: 65% vs. untreated: 54%) (all p < 0.001). Patients with depression, both treated and untreated, had worse postoperative outcomes. Preoperative treatment with antidepressants decreased the effect of depression on adverse outcomes as patients with untreated depression were more likely to experience complications, prolonged stay, readmission, and mortality (all p < 0.001). Patients with untreated depression incurred higher in-hospital and 90-day post-discharge expenditures (no depression: $17,551; treated: $22,086 [7.3% increase]; untreated: $24,897 [10.2% increase]; p < 0.001).</p><p><strong>Conclusions: </strong>Depression reduced the likelihood to achieve optimal postoperative outcomes, yet antidepressant treatment preoperatively mitigated the size of these effects. Screening for depression and initiating appropriate therapy may enhance outcomes.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70210"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12185974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supportive Care Needs of Individuals With Colorectal Cancer in a Low- and Middle-Income Setting: Implications for Advancing Patient-Centered Cancer Care.","authors":"Nur-Nadiatul-Asyikin Bujang, Mahmoud Danaee, Yek-Ching Kong, Muthukkumaran Thiagarajan, Harenthri Devy Alagir Rajah, William E Rosa, Muhd Ash-Shafawi Adznan, Hazzeeq-Safin Hashim, Nur Akmalrudin Nur Dzainuddin, Muhammad Radzi Abu Hassan, April Camilla Roslani, Meheshinder Singh, Wan Zamaniah Wan Ishak, Nirmala Bhoo-Pathy","doi":"10.1002/pon.70190","DOIUrl":"https://doi.org/10.1002/pon.70190","url":null,"abstract":"<p><strong>Background: </strong>Increasing prevalence of colorectal cancer (CRC) demands comprehensive understanding of the corresponding supportive care needs (SCN), especially in low and middle-income settings.</p><p><strong>Aims: </strong>We measured SCN following CRC in a multiethnic, upper middle-income setting, and the associated factors.</p><p><strong>Methods: </strong>Six-hundred-thirty individuals with CRC were recruited from seven oncology centres and a non-governmental organization in Malaysia. A locally developed, and validated 48-item bilingual Needs Assessment Tool for Colorectal Cancer with a 6-point Likert scale was used to assess six domains: diagnosis, psychosocial and information, healthcare, practical, financial, and employment. Vulnerable subgroups were identified using multivariable generalized linear models.</p><p><strong>Results: </strong>High healthcare needs (78.6%) namely shorter hospital waiting times (79.7%) and conveniently located hospital facilities (79.5%), as well as, psychosocial and information needs (70.0%) including easily understood information (87.9%) and compassion from healthcare teams (73.0%) were highly prevalent. High diagnosis (59.4%), financial (36.8%), employment (31.7%), and practical needs (26.7%) also prevailed. Multivariable analyses identified several vulnerable subgroups with high SCN across multiple domains: Younger age (< 60 years) was significantly associated with heightened SCN, especially in psychosocial and information, financial, employment and practical domains. Receiving care in public hospitals was significantly associated with increased psychosocial and information needs, and healthcare needs. Those living with CRC over longer terms (> 3 years vs. 1 year) reported higher practical needs.</p><p><strong>Conclusion: </strong>As the SCN of patients with CRC extend beyond the traditional scope of disease-directed oncology care, addressing high levels of needs in resource-limited settings will require collective action across diverse disciplines and sectors.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70190"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive and Anxiety Symptoms During Chemotherapy for Breast Cancer and the Potential Impact of Pre-Treatment Health Behaviors.","authors":"Gwen W-J Lau, Allison M Deal, Annie B Page, Hyman B Muss, Zev M Nakamura","doi":"10.1002/pon.70204","DOIUrl":"https://doi.org/10.1002/pon.70204","url":null,"abstract":"<p><strong>Objective: </strong>To characterize changes in depressive and anxiety symptoms during breast cancer chemotherapy and investigate how smoking, alcohol use, and physical activity impact these symptoms.</p><p><strong>Methods: </strong>We conducted a secondary analysis of depressive and anxiety symptoms experienced by women with stage I-III breast cancer during the first 12 weeks of chemotherapy. Symptoms were evaluated using single-item measures (PRSM, PRO-CTCAE) at repeated timepoints. Generalized estimating equation methods estimated the odds of experiencing depressive or anxiety symptoms according to baseline smoking, alcohol use, and physical activity, adjusting for age, race, living alone, and chemotherapy regimen. Cochran Mantel Haenszel tests explored relationships between health behaviors and mental health symptom patterns.</p><p><strong>Results: </strong>Among 330 participants, 74% were White, 77% had stage I or II breast cancer, and 41% received anthracycline-based regimens. At least moderately severe depressive and anxiety symptoms were reported by 27% and 38%, respectively, and were most prevalent during the first 3 weeks of chemotherapy. Participants who reported current smoking had higher odds of depressive symptoms compared to those who never smoked (aOR 3.17, 95% CI 1.27-7.96) and higher odds of anxiety symptoms compared to both participants who never (aOR 3.67, 95% CI 1.70-7.95) and previously smoked (aOR 3.03, 95% CI 1.5-6.79). Participants who reported current smoking were also more likely to experience delayed and persistent patterns of anxiety.</p><p><strong>Conclusions: </strong>While depressive and anxiety symptoms declined over time, a substantial minority (≥ 27%) experienced at least moderately severe symptoms during chemotherapy. Patients who smoke may be at particularly elevated risk.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70204"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast and Pelvic Cancer Survivors' Preferences for Psychosexual Interventions to Address Sexual Health Concerns: A Qualitative Study.","authors":"Lauren M Carney, Melanie Besculides, Ksenia Gorbenko, Julie B Schnur, Cindy Munoz, Jezelle Lynch, Carly Feldman, Guy H Montgomery, Vishal Gupta, Sheryl Green, Zahra Ghiassi-Nejad, Karyn A Goodman, Deborah C Marshall","doi":"10.1002/pon.70200","DOIUrl":"https://doi.org/10.1002/pon.70200","url":null,"abstract":"<p><strong>Objective: </strong>Breast and pelvic cancer patients commonly experience sexual dysfunction post-treatment. This study qualitatively examined breast and pelvic cancer survivors' preferences for the delivery and content of psychosexual interventions to address their sexual health concerns post-cancer treatment.</p><p><strong>Methods: </strong>We conducted one-on-one, semi-structured qualitative interviews with 35 female and gender-diverse breast and pelvic cancer survivors who had completed radiotherapy at least 12 months prior to enrollment. Data were analyzed using thematic analysis.</p><p><strong>Results: </strong>Patients preferred a therapist who specialized in sexual health to help them with their sexual concerns. Patients preferred to engage in psychosexual interventions after active treatment was complete. While some patients expected to receive validation and support from a psychosexual intervention in a group format, other patients preferred a one-on-one format due to cultural values which stressed the importance of keeping sexual health concerns private. Finally, patients had several preferences for psychosexual intervention content based on their current unmet psychosexual needs: (a) psychosexual education, (b) help with managing negative thoughts and emotions around sex, (c) communication skills around sex, and (d) help with being flexible in the face of sexual side effects.</p><p><strong>Conclusions: </strong>This study highlights the importance of integrating medical and psychosexual support for breast and pelvic cancer survivors. These results indicate a need to improve training for mental health providers in assessing and treating sexual health concerns, to examine how cultural values may impact patients' preferences for engaging in psychosexual interventions, and to consider the potential impact of sexual script flexibility interventions in this population.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70200"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'As Important as Medication'. A Qualitative Investigation of the Beliefs, Barriers and Facilitators of Physical Activity for Women With Metastatic Breast Cancer.","authors":"Zainab Faatimah Haider, Rebecca J Beeken, Anam Ayaz-Shah, Kelly E Lloyd, Samuel George Smith","doi":"10.1002/pon.70193","DOIUrl":"10.1002/pon.70193","url":null,"abstract":"<p><strong>Background: </strong>Women with metastatic breast cancer (MBC) experience a range of physical and psychological challenges. Physical activity is safe and supports quality of life in individuals with MBC. However, most women with MBC are not meeting physical activity recommendations.</p><p><strong>Aims: </strong>To inform the development of an accessible and effective physical activity intervention, we investigated the beliefs, barriers and facilitators of physical activity of women with MBC.</p><p><strong>Methods: </strong>We conducted semi-structured telephone interviews with UK women living with MBC. Participants were asked open-ended questions about physical activity levels, beliefs, barriers, facilitators, support and preferences. Reflexive thematic analysis was used to analyse the transcripts and themes were mapped onto the Theoretical Domains Framework.</p><p><strong>Results: </strong>23 women with MBC (mean age = 53.7 years; White British = 69.7%) were interviewed between May 2022 and October 2024. Average time since diagnosis was 6 years, 1 month. Most had bone metastases (68.8%). Our analysis generated five themes. Participants generally believed physical activity was important (1) but were limited by physical symptoms (2) and psychological barriers (3). Most women noted a significant lack of physical activity support from healthcare providers (4). They discussed how physical activity could be more accessible for their diverse needs (5), including increasing provision of tailored support.</p><p><strong>Conclusions: </strong>Improvements in physical activity support for women with MBC are needed. Our findings provide several implications for future interventions. This includes implementing physical activity recommendations, improving knowledge about risks and benefits, and incorporating psycho-social and tailored support which consider the unique needs of the MBC population.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70193"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling Anxiety and Depression Symptoms in Patients With Cancer: A Cross-Cultural Comparison Between Brazil and Mexico.","authors":"Cristiane Decat Bergerot, Marcos Espinoza Bello, Joel Flores Juárez, Mónica Ramírez Orozco, Sebastian Hadaegh, Jazmín Hernández Marín, Renata Lemos Ferrari, Errol J Philip, Oscar Galindo Vázquez","doi":"10.1002/pon.70209","DOIUrl":"https://doi.org/10.1002/pon.70209","url":null,"abstract":"<p><strong>Background: </strong>Distress, including symptoms of anxiety and depression, is a common issue for patients with cancer. However, the prevalence and contributing factors can vary across regions due to cultural and systemic differences. This study aimed to assess distress prevalence among patients with cancer in Brazil and Mexico and explore the key factors influencing emotional well-being in these populations.</p><p><strong>Methods: </strong>A cross-sectional study was conducted involving patients from Brazil and Mexico. Participants completed standardized distress screening tools to assess symptoms of anxiety and depression, including the Generalized Anxiety Disorder 7-item scale (GAD-7) and the Patient Health Questionnaire-9 (PHQ-9). Logistic regression analysis was performed to identify associations between distress symptoms and patient characteristics such as age, gender, cancer type, disease stage, and country of origin.</p><p><strong>Results: </strong>A total of 1105 patients with cancer were included in the final analysis. The majority of patients were female (64.8%), married (54.4%), and held at least a college degree (53.0%). The most common diagnosis was breast cancer (32.7%), and most patients were diagnosed at an advanced stage of disease (62.6%). Significant differences in distress prevalence between the two countries were found. Brazilian patients reported higher levels of anxiety symptoms, while Mexican patients exhibited more depressive symptoms (p < 0.001). Multivariate logistic regression showed that gender, age and disease stage were significantly associated with symptoms of anxiety (p < 0.01) and gender with symptoms of depression in both countries.</p><p><strong>Conclusion: </strong>Distress prevalence and its determinants vary across patients in Brazil and Mexico, influenced by cultural, systemic, and healthcare-related factors. Notably, these distress levels are greater than those reported in high-income countries. These findings highlight the need for culturally tailored screening and interventions to address region-specific distress patterns. Targeted psychosocial care can improve emotional well-being and quality of life for patients with cancer in Latin America.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70209"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}