Psycho‐Oncology最新文献

{"title":"Unveiling Anxiety and Depression Symptoms in Patients With Cancer: A Cross-Cultural Comparison Between Brazil and Mexico.","authors":"Cristiane Decat Bergerot, Marcos Espinoza Bello, Joel Flores Juárez, Mónica Ramírez Orozco, Sebastian Hadaegh, Jazmín Hernández Marín, Renata Lemos Ferrari, Errol J Philip, Oscar Galindo Vázquez","doi":"10.1002/pon.70209","DOIUrl":"https://doi.org/10.1002/pon.70209","url":null,"abstract":"<p><strong>Background: </strong>Distress, including symptoms of anxiety and depression, is a common issue for patients with cancer. However, the prevalence and contributing factors can vary across regions due to cultural and systemic differences. This study aimed to assess distress prevalence among patients with cancer in Brazil and Mexico and explore the key factors influencing emotional well-being in these populations.</p><p><strong>Methods: </strong>A cross-sectional study was conducted involving patients from Brazil and Mexico. Participants completed standardized distress screening tools to assess symptoms of anxiety and depression, including the Generalized Anxiety Disorder 7-item scale (GAD-7) and the Patient Health Questionnaire-9 (PHQ-9). Logistic regression analysis was performed to identify associations between distress symptoms and patient characteristics such as age, gender, cancer type, disease stage, and country of origin.</p><p><strong>Results: </strong>A total of 1105 patients with cancer were included in the final analysis. The majority of patients were female (64.8%), married (54.4%), and held at least a college degree (53.0%). The most common diagnosis was breast cancer (32.7%), and most patients were diagnosed at an advanced stage of disease (62.6%). Significant differences in distress prevalence between the two countries were found. Brazilian patients reported higher levels of anxiety symptoms, while Mexican patients exhibited more depressive symptoms (p < 0.001). Multivariate logistic regression showed that gender, age and disease stage were significantly associated with symptoms of anxiety (p < 0.01) and gender with symptoms of depression in both countries.</p><p><strong>Conclusion: </strong>Distress prevalence and its determinants vary across patients in Brazil and Mexico, influenced by cultural, systemic, and healthcare-related factors. Notably, these distress levels are greater than those reported in high-income countries. These findings highlight the need for culturally tailored screening and interventions to address region-specific distress patterns. Targeted psychosocial care can improve emotional well-being and quality of life for patients with cancer in Latin America.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70209"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Explorative Study of the Unspoken Grieving Experiences of Bereaved Family Members-An Indian Perspective.","authors":"Dhayanandan Shanmugam, S G Raman, M Janarthinakani, Bhargavi Ilangovan, Shafika Banoo, Jegan Niwas K","doi":"10.1002/pon.70191","DOIUrl":"10.1002/pon.70191","url":null,"abstract":"<p><strong>Background: </strong>A vast majority of advanced cancer care, including palliative and end-of-life care, is provided by the family members. Loss of loved ones leads to practical, emotional and psychological distress and thereby poor quality of life.</p><p><strong>Aim: </strong>The present study aims to explore the psycho social experiences of bereaved family members in the Indian context.</p><p><strong>Methods: </strong>In this prospective observational qualitative study, bereaved family members were (N = 42) interviewed using a semi-structured in-depth interview schedule, after obtaining consent. Interviews were digitally recorded, transcribed and translated by the researcher. Manual thematic analysis was used for analysing the data collected.</p><p><strong>Results: </strong>The thematic analysis of the transcripts revealed six key themes: Heightened distress, family expectations, emotional conflicts versus collusion, challenges during COVID pandemic, coping with self and others, and gratification from caregiving. Many family members maintained a positive outlook on the care they provided and shared effective coping strategies. However, most reported heightened distress due to the loss of their loved one and struggled with emotional expectations during the grieving process. Negative experiences with collusion and its consequences were also noted. The COVID-19 pandemic's impact, particularly in limiting access to support, was another significant challenge for many family members.</p><p><strong>Conclusion: </strong>caregiving during illness or loss presents significant challenges, including emotional strain, family issues, and external stressors like the COVID-19 pandemic. However, caregivers often find fulfilment and develop effective coping strategies to manage these difficulties. It is essential to address both the emotional and practical aspects of caregiving, particularly during crises, to support family members throughout their journey.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70191"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144187833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Closer Look: Who Are Cancer Caregivers in 2025?","authors":"Leah E Walsh, Allison J Applebaum","doi":"10.1002/pon.70195","DOIUrl":"https://doi.org/10.1002/pon.70195","url":null,"abstract":"","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70195"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metaphors and Stigma in Confucian Culture: A Qualitative Study of Cancer Risk Communication Dilemmas for Cascade Screening Among Hereditary Cancer Families From China.","authors":"Chaonan Jiang, Ye Wang, Wu Jiang, Juan Cai, Lingyan Wang, Xiaodan Wu","doi":"10.1002/pon.70205","DOIUrl":"10.1002/pon.70205","url":null,"abstract":"<p><strong>Objective: </strong>The rate of cascade screening in China is very low, and little attention has been given to the communication of cancer risk. It is important to explore Confucian perspectives to identify cancer risk communication dilemmas for cascade screening among hereditary cancer families in China. This study aimed to gain insight into the processes and barriers of cancer risk communication for cascade screening among hereditary cancer families from the perspective of probands with hereditary cancer within the special Confucian cultural context of China.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 31 probands with hereditary cancer. Thematic analysis was conducted by two researchers. The Consolidated Criteria for Reporting Qualitative Research was used to guide this article.</p><p><strong>Results: </strong>Three major themes related to the processes and dilemmas in cancer risk communication for cascade screening among hereditary cancer families from China emerged: Confucian metaphors framing hereditary cancer as moral condemnation; Social stigma amplifying collective silence; Hereditary cancer means family doom due to poor communication about cancer risk.</p><p><strong>Conclusions: </strong>The findings of this study highlight the urgent need to integrate cultural factors into cancer risk communication and cascade screening strategies for hereditary cancer families in Confucian cultural contexts. By understanding and addressing the impact of Confucian metaphors and social stigma, it is possible to develop more culturally appropriate and effective communication models, which can improve the participation rate of cascade screening, reduce the psychological burden of families, and ultimately improve the prevention and treatment outcomes of hereditary cancer.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70205"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Lessons Learned: A Metaphorical Qualitative Study of Adolescent's Experiences After a Cancer Diagnosis Through Photo Art.","authors":"Ebru Akgün Çıtak, Nebahat Bora Güneş, Ebru Kılıçarslan","doi":"10.1002/pon.70208","DOIUrl":"10.1002/pon.70208","url":null,"abstract":"<p><strong>Background: </strong>A cancer diagnosis during childhood profoundly alters a child's emotional, cognitive, and social world. Beyond medical treatment, the illness experience often becomes a source of deeply personal learning and transformation.</p><p><strong>Aim: </strong>This study aimed to explore the emotional and cognitive insights adolescents gain following a cancer diagnosis, as well as how they interpret and express these learnings symbolically through metaphor and visual representation.</p><p><strong>Method: </strong>A qualitative, interpretive research design was employed. Fifteen adolescents aged 10-18, undergoing cancer treatment in a pediatric oncology clinic, participated in two interviews. A semi-structured interview guide with four open-ended questions was used. In the first interview, adolescents were invited to imagine a symbolic image representing their learnings. In the second interview, face-to-face, in-dept interview was conducted and AI-generated visual prompts based on their metaphors were co-created. The data were analyzed using Braun and Clarke's six-phase thematic analysis.</p><p><strong>Results: </strong>Three major themes emerged: (1) Balancing the Positive and Negative Aspects of Change, (2) Wisdom Through Hardship: Lessons and Insights from the Illness Journey, and (3) Transformation in Perspectives on Life and the Future. Adolescents expressed a wide range of emotional and cognitive shifts, including increased empathy, self-awareness, value formation, and future-oriented thinking. Metaphor analysis revealed symbolic representations of vulnerability, resilience, hope, and inner growth.</p><p><strong>Conclusion: </strong>The study highlights the transformative potential of illness in childhood, emphasizing how adolescents construct meaning, adapt, and evolve through adversity. Incorporating adolescents's metaphorical and visual expressions could enrich psychosocial care practices and provide deeper insight into their inner worlds.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70208"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Interest and Recommendations for Receipt of Polygenetic Risk Scores Among Adults Who Smoked Long-Term: A Descriptive Qualitative Analysis.","authors":"Meghan Underhill, Hayley Dunnack Yackel, Manan M Nayak, Andrea Borondy-Kitts, Sun S Kim, Peter J Castaldi, Mary E Cooley","doi":"10.1002/pon.70192","DOIUrl":"https://doi.org/10.1002/pon.70192","url":null,"abstract":"<p><strong>Objective: </strong>Researchers strive to develop more precise prediction models to understand smoking behaviors, facilitate tailored tobacco treatment and improve early detection of lung cancer, including the use of polygenic risk scores (PRS). This study aimed to better understand participants' knowledge, interest and recommendations for receipt of PRS information. Its specific aims were to (1) describe participants' knowledge and interest in obtaining PRS in the context of smoking behaviors, tobacco treatment and/or early detection of lung cancer and (2) identify patient-reported recommendations for incorporating genetic risk information into clinical care.</p><p><strong>Methods: </strong>A descriptive qualitative approach was used to gather data. A one-time semi-structured interview was conducted at the conclusion of a lung health intervention among individuals who smoked long-term and were eligible for lung cancer screening. Sociodemographic, tobacco, alcohol, and comorbidity data were gathered through an electronic survey. Interviews were audio-recorded, transcribed and analyzed using Braun and Clarke's methods for thematic analysis.</p><p><strong>Results: </strong>Forty-six participants were interviewed. The themes for aim 1 included: (1) knowing about PRS and (2) wanting PRS to prevent and treat tobacco addiction. The themes for aim 2 included: (1) receiving information from health professionals and (2) considering the risks of learning PRS.</p><p><strong>Conclusions: </strong>Results indicate high interest in PRS in clinical settings to help people who smoke to understand their health habits and change behaviors. The need for appropriate framing of risk messages and shared decision making emerged in the interviews.</p><p><strong>Trial registration: </strong>NCT0469129T.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70192"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mediating Role of Early Maladaptive Schemas in the Relationship Between Attachment Styles and Adjustment to Early-Stage Breast Cancer.","authors":"Spyridoula Karveli, Evangelos Karademas, Fiorita Poulakaki, Zoe Antonopoulou, Nikolaos Arkadopoulos, Christos Markopoulos","doi":"10.1002/pon.70196","DOIUrl":"10.1002/pon.70196","url":null,"abstract":"<p><strong>Background: </strong>Individual differences play an important role in adjustment to breast cancer. This longitudinal study explored the potential mediating role of Early Maladaptive Schemas (EMSs) in the relationship between attachment styles and psychological adjustment.</p><p><strong>Methods: </strong>Ninety-five early-stage female breast cancer patients participated in this longitudinal study and completed validated self-report questionnaires within 4 weeks and 12 months post-surgery measuring attachment styles (ECR-R), EMSs (YSQ-S3), anxiety (HADS-A), depression (HADS-D), and quality of life (EORTC-QLQ C30). Structural equation modeling was utilized to test direct and indirect effects.</p><p><strong>Results: </strong>Vulnerability to harm/illness schema had a direct effect on all outcomes, while the enmeshment EMS had a direct effect on anxiety only. Moreover, vulnerability to harm/illness schema fully mediated the relationship between attachment anxiety and psychological outcomes. No significant direct or indirect effects were observed for attachment avoidance.</p><p><strong>Conclusion: </strong>The findings underscore the role of the illness-specific EMS -vulnerability to harm/illness-in psychological distress pathways among breast cancer patients. In non-clinical samples, cancer-related demands and stressors likely amplify the activation of only those schemas closely tied to the psychological challenges of living with cancer, while other EMSs may hold little relevance. Interventions targeting illness-specific EMSs may enhance coping and emotional well-being in this population.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70196"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of a Mobile Application for Gynecological Cancer Patients on Their Physical and Psychosocial Adaptation: A Randomized Controlled Trial.","authors":"Okan Vardar, Pınar Serçekuş","doi":"10.1002/pon.70194","DOIUrl":"10.1002/pon.70194","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine the effect of a mobile application developed for gynecological cancer patients on their physical and psychosocial adaptation.</p><p><strong>Methods: </strong>This is a parallel groups, single blind, randomized, controlled study. The patients included in the study were contacted through social media sites of an association with a high number of members and followers. Block randomization was used and 32 patients were assigned to an intervention group and 32 into a control group. The intervention group used the mobile application and the control group received routine care. Data were gathered with a descriptive characteristics form, The M.D. Anderson Symptom Inventory, The Adaptation to Chronic Illness Scale, The Hospital Anxiety and Depression Scale, The Assessment of Survivor Concerns, The Eastern Cooperative Oncology Group Performance Status. The intervention lasted 8 weeks and a total of three follow-ups were performed: one follow-up before the intervention and two follow-ups after the intervention.</p><p><strong>Results: </strong>Symptom severity, anxiety risk and cancer-related worry decreased and physical, social and psychological adaptation increased in the intervention group compared to the control group.</p><p><strong>Conclusions: </strong>The mobile application developed for gynecological cancer patients can reduce symptom severity, anxiety risk and cancer-related worry and improves physical, social and psychological adaptation. It can be recommended that mobile applications with reliable content should be utilized to enhance physical and psychosocial adaptation of gynecological cancer patients receiving chemotherapy in addition to healthcare.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70194"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical Mistrust in Online Cancer Communities: A Large-Scale Analysis Across 10 Cancer Entities.","authors":"Fabian von Bubnoff, Johannes Werner, Nils R Hebach, Deepti A Chopra, Marc Cicero Schubert","doi":"10.1002/pon.70180","DOIUrl":"10.1002/pon.70180","url":null,"abstract":"<p><strong>Background: </strong>Medical mistrust is a barrier to optimal cancer care. Analyzing social media posts where patients voice mistrust provides an opportunity to understand its variations and derive potential ways to address medical mistrust.</p><p><strong>Aims: </strong>To (1) identify the frequency of mistrust expression in cancer-related Reddit posts, (2) characterize mistrusted entities and reasons for mistrust, and (3) identify emotional tone associated with mistrust.</p><p><strong>Methods: </strong>101,963 posts from 10 entity-specific cancer communities on the social media platform Reddit made before September 30, 2024, were analyzed using a Large Language Model (LLM, \"gpt-4o-mini\") in this cross-sectional study. Performance of the LLM was compared to human raters. Categories for mistrusted entities and reasons for mistrust were developed inductively by human evaluators. Subsequently, posts were assigned to these different categories by the LLM.</p><p><strong>Results: </strong>Of n = 101,963 posts analyzed, 19,159 posts (18.8%) were categorized as expressing mistrust, predominantly directed at healthcare professionals (n = 14,221, 74.2%). Most common reasons for mistrust were \"disregard for patient concerns\" (n = 8176, 42.7%), \"perceived incompetence of medical management\" (n = 4871, 25.4%), and problems in \"communication\" (n = 4060, 21.2%). Mistrust posts commonly contained \"worried\" (n = 5933, 31.0%), \"concerned\" (n = 3623, 18.9%) and \"frustrated\" (n = 3046, 15.9%) tones.</p><p><strong>Conclusions: </strong>Expression of medical mistrust is prevalent in social media and is predominantly directed at healthcare professionals. Mistrust is frequently associated with dismissal of patients' symptoms or concerns, a perceived lack of thoroughness in clinical management and communication difficulties, suggesting these as key actionable areas to address medical mistrust in clinical practice.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70180"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intellectual and Developmental Disabilities and Cancer Symptom Severity: A Matched Retrospective Cohort Study.","authors":"Rachel Giblon, Rinku Sutradhar, Julie Hallet, Rebecca Hansford, Christine Kelly, Natalie Coburn, Shahin Shooshtari, Alyson Mahar","doi":"10.1002/pon.70199","DOIUrl":"10.1002/pon.70199","url":null,"abstract":"<p><strong>Background: </strong>Individuals with intellectual or developmental disabilities (IDD) face increased cancer risks and disparities in cancer care accessibility and quality. Despite these concerns, there is limited research on cancer symptomology among individuals with IDD.</p><p><strong>Aims: </strong>This study explored differences in cancer symptoms between individuals with and without IDD.</p><p><strong>Methods: </strong>We conducted a matched retrospective study of adults in Ontario, Canada, with and without IDD who underwent cancer symptom screening using the Edmonton Symptom Assessment Scale-revised (ESAS-r), a patient-reported outcome measure, within 5 years of a new primary cancer diagnosis. Using administrative health data, we performed 1:1 hard matching of individuals with cancer and IDD to those without IDD on age at diagnosis, sex, diagnosis year, cancer type, and registration at a regional cancer center. Conditional logistic regression models compared odds of moderate to severe and severe cancer symptoms.</p><p><strong>Results: </strong>Among 873 matched pairs, individuals with IDD had higher odds of experiencing severe (vs. moderate, mild, or no) cancer-related symptoms compared to those without IDD. Symptoms included anxiety, depression, drowsiness, pain, shortness of breath, tiredness, and poor well-being. Largest magnitudes of effect were for anxiety (odds ratio; OR: 2.20; 95% confidence intervals, CI: 1.68, 2.89) and depression (OR: 2.16; 95% CI: 1.54, 3.02). Similar trends were observed for moderate to severe cancer symptoms compared to mild or no symptoms.</p><p><strong>Conclusions: </strong>Patients with both cancer and IDD report higher symptom severity than those without IDD, emphasizing the importance of tailored interventions and support services to address their unique needs and alleviate symptom burden.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 6","pages":"e70199"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}