Psycho‐Oncology最新文献

{"title":"Positive Psychological Well-Being in Cancer Caregivers.","authors":"Lisa M Gudenkauf, M Tim Song, Emma P Keane, Isabella S Larizza, Fabian N Adri, Michael Baliousis, Elizabeth L Addington, Judith T Moskowitz, Hermioni L Amonoo","doi":"10.1002/pon.70290","DOIUrl":"https://doi.org/10.1002/pon.70290","url":null,"abstract":"","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 10","pages":"e70290"},"PeriodicalIF":3.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Change in Perceived Cognitive Performance Across Different Age Groups Following First Chemotherapy Infusion in Female Patients With Breast Cancer.","authors":"Hui-Ying Yang, Xiaoyin Li, Aasha I Hoogland, Taylor L Welniak, Yvelise Rodriguez, Kristen M Carpenter, Stacy M Fischer, Anita Y Kinney, Daneng Li, Oanh Nguyen, Daniel M Rotroff, Arshiya Mariam, Donna L Berry, Martine Extermann, Richard Kim, Kimberley T Lee, Heather S L Jim","doi":"10.1002/pon.70288","DOIUrl":"https://doi.org/10.1002/pon.70288","url":null,"abstract":"<p><strong>Background: </strong>Cancer-related cognitive impairment (CRCI) is frequently reported by women with breast cancer after chemotherapy. Yet, the acute effects of a single infusion on perceived cognition remain understudied, especially across different age groups.</p><p><strong>Aims: </strong>This study assessed acute changes in perceived cognition following the first chemotherapy infusion in young (< 40 years), middle-aged (40-64 years), and older adults (≥ 65 years) with breast cancer and identified baseline risk factors associated with worsened CRCI in these age groups.</p><p><strong>Methods: </strong>Chemotherapy-naïve women with breast cancer scheduled for intravenous chemotherapy completed PROMIS Cognitive Abilities 4a and Cognitive Function 8a assessments before and 5 days post-infusion. Clinically significant CRCI was defined as T-scores ≤ 45. Paired t-tests, chi-square tests, and residualized regression models (univariate and multivariable) were used to evaluate changes in cognition and associated risk factors.</p><p><strong>Results: </strong>Among all participants (N = 528; 85 young, 329 middle-aged, 114 older), perceived cognitive performance significantly declined, and the prevalence of CRCI increased across all three age groups (FDR adjusted p-values < 0.05). Among middle-aged patients, the White race (p = 0.011) and a college degree (p = 0.001) were associated with worsened cognitive function, while a college degree (p = 0.009) and sleep disturbance (p = 0.012) were linked to worsened cognitive ability. In older adults, depressive symptoms were associated with worsened cognitive function (p = 0.017) and cognitive ability (p = 0.011).</p><p><strong>Conclusions: </strong>Cognitive impairment develops acutely after the first chemotherapy infusion across all age groups, with risk factors varying by age. Age-specific interventions are needed to address early cognitive decline in breast cancer patients.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 10","pages":"e70288"},"PeriodicalIF":3.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonlinear Associations of Depression and Stigma With Subclinical Hikikomori in Cancer Survivors.","authors":"Wei Zhang, Xiao-Dan Wu, He-Li Sun, Yuan Feng, Qinge Zhang, Zhaohui Su, Teris Cheung, Lili Tang, Gabor S Ungvari, Chee H Ng, Yu-Tao Xiang","doi":"10.1002/pon.70268","DOIUrl":"https://doi.org/10.1002/pon.70268","url":null,"abstract":"<p><strong>Background: </strong>Cancer survivors often experience depression and stigma associated with chronic diseases, which may increase the risk of subclinical hikikomori.</p><p><strong>Aims: </strong>This study examined the prevalence of subclinical hikikomori and its nonlinear associations with depression and stigma among cancer patients.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted among 1951 cancer survivors. Depression and stigma associated with cancer were measured using the Patient Health Questionnaire-9 (PHQ-9) and Stigma Scale for Chronic Illnesses 8-Item Version (SSCI-8) scales, respectively, while subclinical hikikomori was assessed using the 1-month version of the validated 25-item Hikikomori Questionnaire (HQ-25M). Logistic regression and restricted cubic splines analysis were employed to explore the associations between depression, stigma, and subclinical hikikomori.</p><p><strong>Results: </strong>Of the 1951 cancer survivors, the prevalence of subclinical hikikomori was 21.6% (95% CI: 19.8%-23.5%). Both depression (OR = 1.06, 95% CI: 1.033-1.086, p < 0.001) and stigma (OR = 1.16, 95% CI: 1.132-1.182, p < 0.001) were significantly and positively associated with subclinical hikikomori. Nonlinear analyses revealed inflection points at PHQ-9 = 1.96 and SSCI = 9.41, beyond which the association between depression, stigma, and subclinical hikikomori significantly strengthened. Cancer survivors with chronic diseases, first-time cancer diagnoses, or a history of chemotherapy exhibited higher odds ratios of subclinical hikikomori across all measures.</p><p><strong>Conclusions: </strong>Subclinical hikikomori was common among cancer survivors and was significantly associated with both depression and stigma. To prevent subclinical hikikomori, these findings underscore the importance of early intervention to address depression and stigma, especially for those with chronic health conditions, first-time cancer diagnoses, or prior chemotherapies.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 9","pages":"e70268"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lived Experience of Caregivers of Terminally Ill Patients With Cancer: A Phenomenological Study at Ocean Road Cancer Institute in Dar es Salaam, Tanzania.","authors":"Fatuma Kaloya, Masunga K Iseselo, Gift Lukumay","doi":"10.1002/pon.70281","DOIUrl":"https://doi.org/10.1002/pon.70281","url":null,"abstract":"<p><strong>Background: </strong>Caregivers face numerous physical and emotional challenges when providing care to people suffering from life-threatening illnesses such as cancer. The study aimed to explore caregivers' experiences in providing care for terminally ill cancer patients in Dar es Salaam, Tanzania.</p><p><strong>Method: </strong>A phenomenological study design was conducted among caregivers of terminally ill cancer patients at Ocean Road Cancer Institute (ORCI). A purposive sampling technique was used to select a sample size of 10 participants. An in-depth interview method was used to collect the data. A semi-structured interview guide with an audio recorder was used to collect the information from the participants. Data were transcribed verbatim and analysed using a thematic analysis approach.</p><p><strong>Findings: </strong>The three themes were challenges in caring for patients, availability of social support, and coping strategies. Physical exhaustion and burnout, emotional distress and reduced social interaction were the challenges in caring for patients described by participants during the caring process. Family member support, community support and religious support were the available support systems that facilitated caregivers to care for the patients. However, adopting self-distraction towards patient behaviour, acquiring and using practical skills and following professional guidance were the individual coping strategies used by participants in caring for terminally ill cancer patients.</p><p><strong>Conclusion: </strong>Study findings highlight the fundamental role of caregivers in the care, and illuminate the neglected physical, psychological and social challenges they face amidst health system tensions and conflicting roles. The needs of caregivers should be embedded within cancer care, prevention and control programs, particularly in low-resource settings.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 9","pages":"e70281"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating Romantic Relationships and Sexual Intimacy: Challenges and Opportunities for Adolescents and Young Adults With Cancer - A Literature Review of Qualitative Studies.","authors":"Nicole Collaço, Céline Bolliger, Charlotte Cairns, Samantha Sodergren, Olga Husson, Winette T A van der Graaf, Maria Rothmund-Grenier, Milou J P Reuvers, Gudrun E Rohde, Anna L Hurley-Wallace, Konstantinos Angoumis, Emily I Holthuis, Lina H Lankhorst, Catarina S Padilla, Simone Hanebaum, Connor J Tyler, Katherine J Hunt, Kirsty Way, Richard Wagland, Thomas J Cartledge, Thom Legendal, Silvie H M Janssen, Anne-Sophie Darlington","doi":"10.1002/pon.70285","DOIUrl":"10.1002/pon.70285","url":null,"abstract":"<p><strong>Objective: </strong>This review explores the impact of cancer on adolescents' and young adults' (AYAs) romantic and sexual relationships, examining both challenges and opportunities.</p><p><strong>Methods: </strong>Qualitative studies on AYAs with cancer and/or their partners were searched based on a sub-set of studies identified in a previous literature review within the EU Horizon STRONG-AYA project, and supplemented with an additional search on romantic/sexual relationships. Articles were screened, reviewed in Rayyan and data extracted using a structured framework. Study quality was appraised, and findings were synthesised thematically.</p><p><strong>Results: </strong>Twenty studies were included. Findings revealed how cancer altered AYAs' sense of self, affecting the navigation of romantic relationships and sexual intimacy across four themes: (1) Romantic relationship development-connection, isolation and changing priorities: Disrupted romantic trajectories and fears of being undesirable hindered relationship formation, though some re-evaluated priorities, deepening emotional connections, (2) The disclosure dance: Finding the right time and way: AYAs struggled with when and how to disclose their diagnosis, with anxiety about burdening partners or altering dynamics. Open and honest communication fostered intimacy, (3) Body image, sexuality, intimacy, and fertility: Challenges in these areas impacted self-worth, but also led to sexual empowerment and adapted intimacy, (4) Partnerships and social support during cancer: Unsupportive partners heightened isolation, while supportive partners reinforced self-worth. Many AYAs experienced growth, resilience and a deeper understanding of themselves/their relationships.</p><p><strong>Conclusion: </strong>Results may inform age-appropriate interventions to adequately address the unique challenges AYAs with cancer face in navigating romantic relationships and sexual intimacy.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 9","pages":"e70285"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'How Did That Make You Feel?' Latinas' Use of Genetic Counseling and Testing for Hereditary Cancer Risk After Watching a Culturally Targeted Video and Receiving Patient Navigation.","authors":"Sara Gómez-Trillos, Pilar Carrera, Amparo Caballero, Vanessa B Sheppard, Kristi D Graves, Beth N Peshkin, Marc D Schwartz, Claudia Campos, Nathaly Garcés, Alejandra Hurtado de Mendoza","doi":"10.1002/pon.70261","DOIUrl":"https://doi.org/10.1002/pon.70261","url":null,"abstract":"<p><strong>Objective: </strong>Culturally targeted narrative education is a promising approach to cancer prevention and control. This study evaluates the uptake of genetic counseling and testing (GCT) in Latinas at risk for hereditary breast and ovarian cancers (HBOC) after watching a culturally targeted narrative video and being navigated to GCT services.</p><p><strong>Methods: </strong>Latina women at increased risk for HBOC were recruited through community-based organizations. Participants responded to surveys before and after watching Spanish-language telenovela-style video. Surveys measured sociodemographic and clinical variables, HBOC and GCT knowledge, transportation with the story, identification with characters, and emotions elicited by the video. After watching video, participants were offered patient navigation services to free or low-cost GCT and completed a 3-month follow-up phone survey to assess GCT uptake.</p><p><strong>Results: </strong>Participants (N = 40) were 47.35 years old on average (SD = 9.48); all were born outside the United States. At the 3-month follow-up (N = 37), 27 (72.9%) and 26 (70.27%) participants had attended genetic counseling and genetic testing, respectively. U Mann Whitney tests found statistically significant differences between women who attended counseling versus those who did not at baseline knowledge (U = 216.00, p = 0.000) and distress elicited by the video (U = 73.5, p = 0.03). A logistic regression with distress elicited by the video as a predictive variable reached statististical significance (β = -0.27, p = 0.037, CI 95% 0.58-0.98).</p><p><strong>Conclusions: </strong>GCT uptake was promising, supporting a role for culturally targeted narrative video education along with a patient navigation component in increasing interest in cancer prevention and reducing healthcare disparities in HBOC genetic services.</p><p><strong>Trial registration: </strong>NCT03075540 (Initial release 2/22/2017).</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 9","pages":"e70261"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in Decision-Making for Contralateral Prophylactic Mastectomy in Korea: A Qualitative Study of Perspectives of Patients With Hereditary Breast Cancer and Providers.","authors":"Sun-Young Park, Youlim Kim, Maria C Katapodi, Hye Jin Chun, Dohee Ahn, Mijin An, So-Youn Jung","doi":"10.1002/pon.70266","DOIUrl":"https://doi.org/10.1002/pon.70266","url":null,"abstract":"<p><strong>Background: </strong>The uptake of contralateral prophylactic mastectomy (CPM) has increased among patients with breast cancer and BRCA-pathogenic variants. However, CPM decision-making remains complex, involving various risks and benefits, and requiring comprehensive patient support. This study explored patients' and healthcare providers' (HCPs') perspectives during CPM decision-making in the Korean healthcare context.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 17 patients with breast cancer and BRCA pathogenic variants and 10 HCPs (7 breast surgeons, 3 advanced practice nurses) between August and September 2024. A reflexive thematic analysis was conducted based on Charles's decision-making model.</p><p><strong>Results: </strong>Three themes emerged across decision-making stages for both patients and HCPs. Patients needed more information and guidance during the information exchange phase. In contrast, HCPs hesitated to guide decision-making due to limited CPM evidence, negative perceptions of CPM, and time constraints. During the deliberation phase, patients required more counseling and trust-building with HCPs. However, HCPs faced resource constraints (time, staff, space), hindering these supports. In the decision-making phase, patients' preferences varied, ranging from autonomous to physician-led decisions, whereas HCPs maintained neutrality, recognizing patients as primary decision-makers. These opposing positions create a mismatch in decision-making role expectations between patients and HCPs.</p><p><strong>Conclusion: </strong>This study highlights gaps and challenges in information, support, and decision-making roles between patients and HCPs. A shared decision-making approach, backed by insurance reimbursement, could help bridge these gaps. Providing additional resources- counseling time, staffing, space, and decision aids-may improve patient-centered decision-making in the Korean healthcare context.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 9","pages":"e70266"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Trajectories of Fear of Cancer Recurrence: A Longitudinal Study on the Spouses of Young and Middle-Aged Breast Cancer Patients After Postoperative Chemotherapy\".","authors":"","doi":"10.1002/pon.70241","DOIUrl":"https://doi.org/10.1002/pon.70241","url":null,"abstract":"","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 9","pages":"e70241"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking the Conspiracy of Silence: Staging Loss.","authors":"Philip Vassallo","doi":"10.1002/pon.70270","DOIUrl":"https://doi.org/10.1002/pon.70270","url":null,"abstract":"","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 9","pages":"e70270"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Distress Among Colorectal Cancer Patient-Caregiver Dyads: Influencing Factors and Dyadic Intervention Preferences-A Mixed Methods Study.","authors":"Xiaoxiao Hu, Qiaomei Zhang, Honghong Wang, Jiping Tan, Qingchun Geng, Hongwen Ma, Yanfei Jin","doi":"10.1002/pon.70287","DOIUrl":"https://doi.org/10.1002/pon.70287","url":null,"abstract":"<p><strong>Background: </strong>Colorectal cancer imposes substantial psychological distress on patients and spouse caregivers, yet dyadic distress interactions, key influencing factors, and effective interventions remain insufficiently understood.</p><p><strong>Aims: </strong>To assess psychological distress levels in colorectal cancer patient-caregiver dyads, identify influencing factors, explore dyadic intervention patterns, and gather professional suggestions for prevention and mitigation strategies.</p><p><strong>Methods: </strong>A mixed-methods study with an explanatory sequential design was conducted. Quantitatively, 259 colorectal cancer patient-caregiver dyads from three tertiary hospitals completed surveys measuring psychological distress, perceived stress, relationship satisfaction, and distress disclosure. Qualitatively, in-depth interviews were conducted with 10 patient-caregiver dyads and 10 healthcare providers using maximum variation sampling.</p><p><strong>Results: </strong>Both patients and caregivers demonstrated significant psychological distress. For patients, key predictors included relationship satisfaction, distress disclosure, and perceived stress. For caregivers, significant predictors were caregivers' age, caregiving hours, relationship satisfaction, distress disclosure, perceived stress, and patients' relationship satisfaction. A distinctive \"mutual protection through concealment\" pattern emerged, where both patients and caregivers concealed distress to protect each other. Qualitative findings also identified additional distress triggers (role changes, symptom burden, prolonged caregiving) and protective factors (relationship support, acceptance, and open communication).</p><p><strong>Conclusions: </strong>Healthcare professionals should address psychological distress in colorectal cancer dyads through targeted interventions, considering dyadic interaction patterns. Interventions should include relationship strengthening, communication skills training, caregiver support with attention to their health status, symptom management education, and strategies addressing the culturally influenced mutual concealment pattern to promote authentic emotional disclosure, reduce psychological distress, and improve quality of life for both patients and caregivers.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 9","pages":"e70287"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}