Psycho‐Oncology最新文献

{"title":"Pain Experiences During Early Treatment for Pediatric Acute Lymphoblastic Leukemia: A Qualitative Study.","authors":"Kimberly L Klages, Cecelia I Nelson, Julia K Herriott, Robin E Norris, Meghan E McGrady, Susmita Kashikar-Zuck, Ahna L H Pai","doi":"10.1002/pon.70550","DOIUrl":"10.1002/pon.70550","url":null,"abstract":"<p><strong>Background: </strong>Pain is a common and distressing symptom for pediatric patients with acute lymphoblastic leukemia (ALL), arising from the disease itself, its treatment, and associated medical procedures. The early phase of treatment is particularly challenging, as children experience multiple, rapidly evolving sources of pain. Despite its prevalence, pain during this period remains poorly characterized. This study qualitatively examined pain experiences among children with ALL during induction and early consolidation.</p><p><strong>Methods: </strong>Twenty caregivers of children with ALL (ages 2-17) and eight patients (ages 8-17) participated in two semi-structured interviews capturing pain experiences across early treatment. Interviews were audio-recorded, transcribed, and analyzed using thematic analysis.</p><p><strong>Results: </strong>Eight themes described key dimensions of the pain experience: Sources of Pain, Pain Characteristics, Pain-Related Symptoms, Factors Influencing Pain, Pain Impact, Pain Expression, Pain Management Tools, and Barriers to Pain Management. These themes reflected the evolving, multidimensional nature of pain during early treatment.</p><p><strong>Conclusions: </strong>Children with ALL experience substantial and multifaceted pain early in their cancer trajectory. Findings underscore the need for early, developmentally informed, and family-centered approaches to pain assessment and management that address the complex and evolving nature of pain during initial treatment.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70550"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13366143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148437891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Image Concerns and Associated Factors up to Five Years After Cancer in Young Adulthood: A Swedish Longitudinal Population-Based Study.","authors":"Rebecca Skog, Sarah Marklund, Claudia Lampic, Lena Wettergren","doi":"10.1002/pon.70545","DOIUrl":"10.1002/pon.70545","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate prevalence of body image disturbance and how perceptions of the body evolve from 1.5 to 5 years following a cancer diagnosis in young adulthood. Additionally, to identify factors associated with worse body image over time.</p><p><strong>Methods: </strong>A population-based longitudinal study with 1010 individuals diagnosed with breast-, cervical-, ovarian-, testicular cancer, brain tumor or lymphoma at ages 18-39 years was conducted. Participants were approached with surveys 1.5, 3 and 5 years post-diagnosis. Body image was assessed using the Body Image Scale (BIS). Linear mixed models with random intercepts were used to investigate change in body image.</p><p><strong>Results: </strong>Approximately half of females and a fourth of males reported clinical levels of body image disturbance (≥ 10) at 1.5 years post diagnosis, followed by ∼40% and ∼15% respectively at follow-ups. The highest level of body image disturbance was reported among those diagnosed with breast cancer and lymphoma. Body image improved over time among male survivors and females diagnosed with breast cancer and lymphoma (p < 0.001), while other groups remained stable (all p > 0.05). Factors associated with worse body image in both models included intensive treatment and emotional distress.</p><p><strong>Conclusions: </strong>Although body image was found to improve over time among males and females with breast cancer and lymphoma, a substantial proportion report persistent body image disturbance at follow-up. Future research should employ qualitative methods in exploring the experiences and needs of young adults following cancer, in order to develop timely support for alleviating body image problems.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70545"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13379270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148472028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Activation, Patient-Physician Communication Quality, and Cancer-Related Fatigue: A Longitudinal Study of Cancer Survivors.","authors":"Duc Truong Nguyen, Martina E Schmidt, Marlena Milzer, Anna S Wagner, Senta Kiermeier, Imad Maatouk, Karen Steindorf","doi":"10.1002/pon.70542","DOIUrl":"10.1002/pon.70542","url":null,"abstract":"<p><strong>Objective: </strong>Cancer-related fatigue (CRF) is highly prevalent and often insufficiently addressed in routine survivorship care. This study examined whether patient activation and patient-physician communication quality in early survivorship are associated with subsequent CRF among cancer survivors.</p><p><strong>Methods: </strong>The observational German LIFT study enrolled 1175 adult survivors of various cancer types. CRF was assessed 4-6, 9, 12, and 24 months post-diagnosis using the EORTC QLQ-FA12. Patient activation was assessed with the German Patient Activation Measure (PAM-13-D (PAM)) and communication quality with an exploratory five-item scale (ComQ) 9 months after diagnosis. Multiple linear regression models examined associations of PAM and ComQ with physical and total CRF 12 months (n = 1132) and 24 months (n = 1067) after diagnosis, adjusting for sociodemographic and clinical covariates. Sensitivity analyses additionally adjusted for previous CRF 4-6 months after diagnosis. Missing data among alive participants were multiply imputed.</p><p><strong>Results: </strong>PAM at 9 months was negatively associated with physical and total CRF at both 12 and 24 months after diagnosis, whereas ComQ at 9 months was negatively associated with physical and total CRF at 12 months only. After additional adjustment for previous CRF at 4-6 months, negative associations for PAM with physical and total CRF persisted at 12 months but were attenuated.</p><p><strong>Conclusions: </strong>Higher patient activation and better perceived patient-physician communication were associated with lower subsequent CRF, particularly within the first year after diagnosis. Activation-oriented and communication-focused strategies may complement existing CRF interventions and warrant further evaluation in pragmatic trials across different survivor groups and settings.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70542"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13370050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Minority Within a Minority: Lived Meanings of Cancer Among Arab Young Adults in East Jerusalem.","authors":"Rola Abd Elgani, Yaffa Naomi Stokar","doi":"10.1002/pon.70547","DOIUrl":"10.1002/pon.70547","url":null,"abstract":"<p><strong>Objective: </strong>Young adulthood is a socially and biographically formative life stage, yet young adults from ethnic-national minority groups remain underrepresented in psycho-oncology research. This study examined how Arab young adults (YA) from East Jerusalem make meaning of cancer while receiving treatment in predominantly Jewish-Israeli hospitals.</p><p><strong>Methods: </strong>Guided by a context-informed, constructivist qualitative framework, we conducted semi-structured, in-depth interviews with 15 Arab YA (aged 23-45) who were undergoing active cancer treatment. Interviews were conducted in Arabic, transcribed verbatim, and analyzed using reflexive thematic analysis to capture culturally and developmentally embedded meanings of illness and care.</p><p><strong>Results: </strong>Two interrelated sets of lived meanings emerged. First, participants described cancer through culturally embedded frameworks shaped by stigma, secrecy, family responsibility, and faith-based interpretations that provided meaning and emotional containment. These meanings were closely tied to the future-oriented concerns and relational obligations of young adulthood. Second, participants experienced Israeli hospitals as ambivalent institutional spaces: often perceived as safe, compassionate, and politically neutral yet at times marked by cultural misattunement, language barriers, and subtle inequality. Together, the findings show that cancer was experienced not only as a medical condition but as a deeply contextualized social and developmental experience.</p><p><strong>Conclusions: </strong>The experience of cancer among Arab YA from East Jerusalem is shaped by the intersection of developmental stage, minority positioning, and institutional context. These findings highlight the importance of context-informed and culturally responsive psycho-oncology care for young patients from socially and politically marginalized backgrounds.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70547"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13370051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction Models for Psychological Distress in Patients With Malignant Tumors: A Scoping Review.","authors":"Huangli Chen, Wenjing Zhang, Xinyu Li, Junyi Li, Xiaodong Ning, Xueqin Yang","doi":"10.1002/pon.70540","DOIUrl":"10.1002/pon.70540","url":null,"abstract":"<p><strong>Objective: </strong>Psychological distress is common among patients with malignant tumors and adversely affects treatment adherence and quality of life. Numerous prediction models have been developed to identify high-risk patients, yet few have been implemented clinically. This scoping review synthesizes the development methods, performance, validation methods, and limitations of existing models to inform future research and support clinical translation.</p><p><strong>Methods: </strong>Following the Joanna Briggs Institute (JBI) methodology, eight databases were searched from inception to June 10, 2026. Two reviewers independently conducted screening, data extraction, and quality assessment.</p><p><strong>Results: </strong>Thirteen studies involving 26 prediction models were included. Logistic Regression (LR), Random Forests (RF), eXtreme Gradient Boosting (XGBoost), and Artificial Neural Network (ANN) were the most common development methods. Reported sensitivities ranged from 0.518 to 0.968, specificities from 0.651 to 1.000, and Areas Under the Curve (AUCs) from 0.673 to 1.000. Thirteen studies underwent internal validation only; none underwent external validation, and all were rated as high risk of bias. Frequently included predictors were tumor stage, sleep quality, pain degree, age, financial problems, and coping style. Nomograms and web-based calculators were the predominant presentation formats.</p><p><strong>Conclusion: </strong>Although models developed using XGBoost, RF, and ANN reported high performance, these findings are likely inflated due to small sample sizes, low Events Per Variable (EPV), and lack of external validation. Future research should strengthen methodological rigor, increase sample sizes, and conduct external validation to support clinical adoption.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70540"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148405567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Psychological Resilience in Colorectal Cancer Patients: A Comprehensive Mixed Methods Systematic Review\".","authors":"","doi":"10.1002/pon.70535","DOIUrl":"10.1002/pon.70535","url":null,"abstract":"","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70535"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Impact of Spine Sarcoma on Wellbeing.","authors":"V Williamson, G Mawhinney, D Cimatu, T Land, J J Reynolds","doi":"10.1002/pon.70546","DOIUrl":"10.1002/pon.70546","url":null,"abstract":"<p><strong>Background: </strong>Spine sarcomas are rare but debilitating cancers requiring extensive treatment with high morbidity. While physical outcomes are well studied, the psychological impact and support needs of patients remain poorly understood. The aim of this study was to qualitatively explore patient experiences of spine sarcoma on wellbeing and their perceived support needs.</p><p><strong>Method: </strong>Sixteen adult patients diagnosed or treated for spinal sarcoma at Oxford University Hospitals completed semi-structured qualitative interviews. Data were analysed using thematic analysis.</p><p><strong>Results: </strong>Patients frequently experienced significant delays to diagnosis, often enduring severe, persistent pain and having requests for further diagnostic tests declined by healthcare providers. After diagnosis, many underwent extensive and invasive treatment, with prolonged hospital stays and reliance on considerable caregiving support after discharge. Emotional challenges were common, including anger, anxiety and social withdrawal, often compounded by chronic pain and reduced mobility. Patients also described unmet rehabilitative care needs, including fragmented aftercare and limited psychological provision.</p><p><strong>Conclusions: </strong>Findings underscore the urgent need for earlier diagnosis, enhanced clinical training, integrated psychosocial support, and coordinated long-term survivorship care in spinal sarcoma.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70546"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13373986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148472379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing Dimensional Models of Psychopathology in Cancer: Insights From Applying the Hierarchical Taxonomy of Psychopathology (HiTOP).","authors":"Darren Haywood, Jai Carmichael, Miriam K Forbes, Roman Kotov, Robert F Krueger, Aidan G C Wright, Susan L Rossell, David Castle, Wendy Lam, Maryam Lustberg, Colin E Vize, Anna Ugalde, Phyllis Butow, Nicolas H Hart","doi":"10.1002/pon.70533","DOIUrl":"10.1002/pon.70533","url":null,"abstract":"<p><strong>Objective: </strong>Cancer survivors, defined as those living with or beyond a cancer diagnosis, experience more than double the prevalence of psychopathology when compared to the general population. Categorical diagnostic systems, such as the Diagnostic and Statistical Manual of Mental Disorders (DSM), remain dominant in psycho-oncology despite concerns about reliability, validity, and clinical utility for this population. Dimensional frameworks, such as the Hierarchical Taxonomy of Psychopathology (HiTOP), offer a more precise alternative; however, they have not yet been widely applied in cancer survivors. Accordingly, the objective of this research was to examine the applicability of HiTOP to cancer survivors.</p><p><strong>Methods: </strong>Data from 1389 participants in 28 countries (n = 728 cancer survivors; n = 661 community/psychiatric) were collected using the 405-item HiTOP-SR, alongside demographic, clinical, and cancer-specific measures. The HiTOP-SR normative sample (n = 780) was also used. Analyses included parametric, non-parametric, and factor analytic approaches.</p><p><strong>Results: </strong>All HiTOP-SR scales demonstrated strong homogeneity and reliability in cancer survivors. Cancer survivors showed significant elevations across Internalising and Somatoform spectra, with current cancer associated with additional elevations in domains of Thought Disorder and components of Disinhibited and Antagonistic psychopathology. An 11-factor model was developed and supported for both cancer and community/psychiatric samples, though the magnitudes of the factor loadings sometimes varied between samples. External validity was strong with theoretically aligned associations.</p><p><strong>Conclusion: </strong>The HiTOP-SR appears reliable within cancer survivors and provides utility in quantifying a broad array of psychopathology experienced. The results highlight the potential applicability and utility of HiTOP to improve cancer research and clinical practice in psycho-oncology.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70533"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13307643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148339989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial Impact of Sarcoma: Challenges and Adaptation, a Meta-Synthesis.","authors":"R Beghean, L O'Driscoll, E Ryan, P Carty, F Larkin, F O'Keeffe","doi":"10.1002/pon.70534","DOIUrl":"10.1002/pon.70534","url":null,"abstract":"<p><strong>Objectives: </strong>Sarcoma is a rare and heterogeneous cancer frequently associated with significant psychosocial burden. This review aims to synthesise qualitative research to examine the psychosocial impact of sarcoma in adults, focusing on how individuals experience and make sense of disruption across diagnosis, treatment, recovery, and survivorship, the ways they adapt to these challenges, and the psychosocial needs they identify throughout the sarcoma trajectory.</p><p><strong>Methods: </strong>A preregistered systematic review (PROSPERO CRD42024571502) was conducted following PRISMA and ENTREQ guidance. Four databases were searched (PsycINFO, MEDLINE, CINAHL, and Web of Science), and peer-reviewed qualitative studies involving adults with sarcoma were included. Updated search conducted on 30/12/2025. Study quality was appraised using CASP, and data were synthesised using inductive thematic synthesis to integrate experiential accounts and generate analytical insights.</p><p><strong>Results: </strong>Forty studies published between 2008 and 2025 involving 538 participants were included, with most rated high methodological quality. Five themes captured sarcoma as a cumulative psychosocial disruption, beginning with diagnostic delay and uncertainty, intensifying through invasive treatment and prolonged recovery, and extending into enduring changes in body image, function, identity, and social participation. Adaptation emerged as a dynamic, ongoing process involving self-management, meaning-making, selective information engagement, and reliance on relational and professional support. Persistent unmet needs were identified, particularly regarding specialist, coordinated care and sarcoma-informed rehabilitation.</p><p><strong>Conclusions: </strong>Experiences of sarcoma as adults are characterised by prolonged psychosocial disruption requiring adaptation across all stages of the illness. Findings highlight the importance of specialist, continuous, and rehabilitation-focused sarcoma care to support long-term adjustment and wellbeing.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70534"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13340199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148397555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introducing the Ottawa Clinical Fear of Recurrence-Self-Report; A New Assessment Tool for Clinical Fear of Cancer Recurrence.","authors":"Lauriane Giguère, Emma Kearns, Suchithra Shenthil, Brittany Mutsaers, Cheryl Harris, Allan 'Ben' Smith, Gerald M Humphris, Daniel Costa, Cary S Kogan, Sébastien Simard, Sophie Lebel","doi":"10.1002/pon.70537","DOIUrl":"10.1002/pon.70537","url":null,"abstract":"<p><strong>Background: </strong>The Ottawa Clinical Fear of Recurrence-Self-Report (OCFR-SR) was developed to enable brief assessment of clinically significant fear of cancer recurrence (FCR) according to recently updated criteria based on expert consensus: a) high levels of worry, b) high levels of preoccupation, c) hypervigilance of bodily symptoms, and d) that last for more than 3 months.</p><p><strong>Aim: </strong>The study evaluated the OCFR-SR item pool with the goal of optimizing its brevity and psychometric properties.</p><p><strong>Methods: </strong>The OCFR-SR's 23 candidate items were administered to mixed cancer survivors recruited from The Ottawa Hospital along with other assessment measures within the questionnaire package. Eligible participants had to have been diagnosed with any cancer, stages I-III, and have completed primary treatment. Exploratory factor analysis, item response theory, and internal reliability were used to optimize the number of items. Internal (MacDonald's omega and Cronbach's alpha) and test-retest reliability (intra-class correlation) were assessed. Finally, convergent and discriminant validity were explored (Pearson correlations and z-tests).</p><p><strong>Results: </strong>A total of N = 296 survivors completed the questionnaire package. Seven items were selected for the final version of the OCFR-SR. All items performed similarly on psychometric assessments. Theoretical considerations were decisive in selecting the final items. The final OCFR-SR demonstrated satisfactory convergent and discriminant validity, and internal and test-retest reliability.</p><p><strong>Conclusions: </strong>This study introduces the final seven-item OCFR-SR, enabling clinicians and researchers to assess the clinical significance of FCR according to the recently updated criteria. It is the first brief self-report tool aimed at assessing clinical FCR.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 7","pages":"e70537"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13340200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148397596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}