Psycho‐Oncology最新文献

{"title":"Getting Cancer Is \"Just Bad Luck\": Exploring Bereaved Emerging and Young Adults' Cancer Risk Uncertainty After Caring for a Parent With Advanced Cancer.","authors":"Amanda Kastrinos, Caroline Salafia, Rebecca R Gebert, Emily L Mroz, Carla L Fisher, Allison J Applebaum","doi":"10.1002/pon.70161","DOIUrl":"https://doi.org/10.1002/pon.70161","url":null,"abstract":"<p><strong>Background: </strong>Emerging and young adult caregivers (EYACs) who provide care to a parent with advanced cancer are underrepresented in caregiving scholarship, and yet, are not uncommon. Little is known about the psychosocial impacts of caring for a parent at this age or how EYACs manage their uncertainty regarding their own, potentially elevated, future cancer risk.</p><p><strong>Aims: </strong>To employ Uncertainty Management Theory (UMT) to examine how bereaved EYACs of a parent who died of advanced cancer appraise and manage their uncertainty regarding their personal cancer risk.</p><p><strong>Methods: </strong>We conducted a secondary analysis of in-depth, semi-structured interviews with EYACs (age 18-35) who cared for a parent who died of advanced cancer (n = 33) < 5 years prior. The interviews were transcribed and thematically analyzed.</p><p><strong>Results: </strong>Some EYACs described appraising their cancer risk uncertainty as an opportunity and were motivated to reduce their risks through behavior choices. Others appraised it as a danger and experienced anxiety, paranoia, and fatalism about their risk. Others described their parents' cancer as \"just bad luck,\" believing it to be a random anomaly that could not impact their cancer risk and reported no changes in their appraisal of their cancer risk uncertainty.</p><p><strong>Conclusions: </strong>EYACs' opportunity and danger appraisals align with studies of high hereditary risk populations but reporting no change in cancer risk uncertainty is unique. The long-term health implications of appraising their parent's cancer as a random occurrence, disconnected from their personal risk, remain unknown. Future research should seek to help both bereaved and active EYACs better understand their cancer risk and manage their uncertainty.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 5","pages":"e70161"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Facilitators and Barriers to Cancer Screening Participation Across Southeastic Asia: A Scoping Review\".","authors":"","doi":"10.1002/pon.70163","DOIUrl":"10.1002/pon.70163","url":null,"abstract":"","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 5","pages":"e70163"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"War and Cancer: Exploring Patient Narratives in a Randomized Integrative Oncology Study.","authors":"Eran Ben-Arye, Orit Gressel, Yael Keshet, Vika Zaritsky, Sameer Kassem, Yakir Segev, Noah Samuels","doi":"10.1002/pon.70172","DOIUrl":"https://doi.org/10.1002/pon.70172","url":null,"abstract":"<p><strong>Study objective: </strong>The current war in Israel has affected quality of life (QoL)-related concerns among patients with cancer. Integrative oncology (IO) provides complementary medicine within supportive and palliative care. The study examined an IO program in northern Israel for cancer and war-related concerns.</p><p><strong>Methods: </strong>This qualitative study, nested within a prospective randomized controlled trial, examined patients undergoing oncology and palliative care expressing cancer and war-related QoL concerns referred by oncology healthcare providers to an IO program. Patients were randomized to manual-relaxation with (Group A) or without (Group B) acupuncture. Narratives were recorded in MYCaW (Measure Yourself Concerns and Well-being) questionnaires immediately and after 24 h. Narrative excerpts were qualitatively analyzed using ATLAS.Ti software for systematic coding.</p><p><strong>Results: </strong>Patient narratives (Group A, 67; Group B, 58) focused primarily on themes which included a sense of calmness and reduced emotional distress (e.g., stress, anxiety, worries, nervousness), more prominently in Group B (manual-relaxation only; 55/56 immediately/after 24 h); and reduced pain severity, more so in Group A (with acupuncture; 19/24). Most excerpts described improved QoL in both groups (142/147, 97%) immediately after IO treatments, less so at 24 h (103/135).</p><p><strong>Conclusions: </strong>Narratives of patients facing cancer- and war-related QoL challenges due to the ongoing war in Israel describe a beneficial impact of IO treatments, both immediately and after 24 h. Manual-relaxation without acupuncture was more likely to improve emotional concerns, with pain relief more apparent with the addition of acupuncture. Further qualitative and quantitative research is needed to explore these findings.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 5","pages":"e70172"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health in Familial Adenomatous Polyposis: A Systematic Review.","authors":"M J Mol, H Bouchiba, A S Aelvoet, F Bennebroek Evertsz, F A M Duijkers, J G Karstensen, B A J Bastiaansen, E Dekker, E M A Bleiker","doi":"10.1002/pon.70176","DOIUrl":"10.1002/pon.70176","url":null,"abstract":"<p><strong>Objective: </strong>Familial adenomatous polyposis (FAP) is a hereditary disposition causing a nearly 100% risk of developing colorectal cancer without treatment. Therefore lifelong endoscopic surveillance and prophylactic colectomy, generally before the age of 30, are offered. Children of genetically confirmed FAP-patients have a 50% risk of inheriting the disease. It is a challenge to cope with the burden of FAP. The aim of this systematic review was to study the literature on the presence of mental issues, including anxiety, depression, distress, intellectual disability, and symptoms in the autism spectrum in FAP-patients.</p><p><strong>Methods: </strong>A search was performed in PubMed, EMBASE and Cochrane Library to retrieve English studies on mental health and FAP from inception to May 2024.</p><p><strong>Results: </strong>Of the 2045 identified papers, 35 met our criteria. Most papers did not show increased levels in mean scores of distress, anxiety or depression. However, subgroups with high levels of distress, anxiety and depression were identified, specifically around the time of genetic testing and bowel surgery. Associations between FAP and co-occurrent psychiatric disorders and lower cognitive function were suggested.</p><p><strong>Conclusions: </strong>In conclusion, there is some evidence that co-occurrent psychiatric disorders and intellectual deficits are more prevalent in FAP-patients compared to the general population. During genetic testing and bowel surgery, distress, anxiety and depressive symptoms in subgroups of FAP-patients might be increased. As FAP is a rare disease and sample sizes were small, firm conclusions cannot be drawn. Large prospective studies on mental health issues over time are needed.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 5","pages":"e70176"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Efficacy and Budget Impact of a Tailored Psychological Intervention Program Targeting Cancer Patients With Adjustment Disorder: A Randomized Controlled Trial\".","authors":"","doi":"10.1002/pon.70153","DOIUrl":"https://doi.org/10.1002/pon.70153","url":null,"abstract":"","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 4","pages":"e70153"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facilitators and Barriers to Cancer Screening Participation Across Southeastic Asia: A Scoping Review.","authors":"Isabelle Higgins, Paige Kleinig, Duy Toan Le, Jade Londema, Benn Shephard, Emily Mei Qiong Siow, Ekam Sohal, Saravana Kumar","doi":"10.1002/pon.70139","DOIUrl":"10.1002/pon.70139","url":null,"abstract":"<p><strong>Objective: </strong>As the prevalence of cancer cases in Southeast Asia (SEA) increases, understanding facilitators and barriers to participation in and uptake of cancer screening is important. However, to date, no review has been undertaken on this topic. This review aimed to address this knowledge gap.</p><p><strong>Methods: </strong>The search was conducted across academic databases and grey literature sources. Two reviewers independently screened the results, followed by data extraction. Social cognitive therapy was used as part of narrative synthesis of the data.</p><p><strong>Results: </strong>Of the 735 studies, 26 were included. Barriers and facilitators were grouped into headings of personal, environmental, societal, and behavioural domains. The commonly reported barriers to participation in cancer screening included poor knowledge, emotional factors, belief of low personal susceptibility, lack of time, misperceptions, cost, inconvenience, social influence, and lack of skills required. The facilitators were education, greater self-perceived risk, reassurance, past medical history, reduced cost and improved access to healthcare, social supports, religious beliefs, and routine health check-ups.</p><p><strong>Conclusions: </strong>A multitude of barriers, and some facilitators, to participation in cancer screening were reported in the literature. This complexity highlights the importance of a multifaceted and nuanced strategy in promoting cancer screening in SEA countries.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 4","pages":"e70139"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11969030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying the Influence of Psychosocial Characteristics, Supportive Care Needs and Quality of Life on Breast Cancer Survival.","authors":"Kieran Arasu, Kou Kou, Belinda Goodwin, Suzanne Chambers, Jeff Dunn, Chris Pyke, Peter Baade","doi":"10.1002/pon.70146","DOIUrl":"https://doi.org/10.1002/pon.70146","url":null,"abstract":"<p><strong>Objective: </strong>To identify the contribution of psychosocial characteristics, supportive care needs, or quality of life on breast cancer survival outcomes.</p><p><strong>Methods: </strong>This study used data from a population-based longitudinal study involving women diagnosed with invasive breast cancer (n = 3326, response rate = 71%) in Queensland, Australia, 2010-2013, and followed up to 2020. Flexible parametric survival models were used to identify which factors were associated with survival outcomes. Model fit was assessed using D and <math> <semantics> <mrow><msubsup><mi>R</mi> <mi>D</mi> <mn>2</mn></msubsup> </mrow> <annotation>${R}_{D}^{2}$</annotation></semantics> </math> statistics.</p><p><strong>Results: </strong>Unmet physical and daily living needs, social support, age, stage at diagnosis, tumour grade, clinical subtype and mode of detection explained 39% of survival variability ( <math> <semantics> <mrow><msubsup><mi>R</mi> <mi>D</mi> <mn>2</mn></msubsup> </mrow> <annotation>${R}_{D}^{2}$</annotation></semantics> </math> 0.39; 95% CI 0.33-0.44), with a Harrell's C statistic of 0.84 (95% CI 0.81-0.86). Unmet physical and daily living needs and social support, which fall under the categories of supportive care needs and psychosocial characteristics respectively, were identified as key factors that predict breast cancer survival, explaining 3% of survival variability. When compared to women who had less unmet physical needs and adequate social support (5-year survival: 96.6%, 95% CI 92%-99%), those who had more unmet physical needs and limited social support had poorer breast cancer-specific survival (5-year survival: 86.8%, 95% CI 72%-95%).</p><p><strong>Conclusion: </strong>The study found that unmet physical and daily living needs and social support play a marginal but significant role in influencing breast cancer outcomes. The findings enhance the current literature regarding the impact of psychosocial characteristics and supportive care needs on breast cancer survival and suggest that integrating psychosocial support and interventions alongside medical treatment may further improve the survival outcomes for women diagnosed with breast cancer.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 4","pages":"e70146"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11989191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Sexual Script Flexibility and Sexual Outcomes: An Investigation Among Breast Cancer Survivor Couples.","authors":"Jennifer Barsky Reese, Kristen A Sorice, Laura S Porter, Stephen J Lepore, Shelby L Langer, Jill Hasler, Caroline F Pukall","doi":"10.1002/pon.70147","DOIUrl":"https://doi.org/10.1002/pon.70147","url":null,"abstract":"<p><strong>Objectives: </strong>Breast cancer (BC) survivors often experience sexual concerns affecting their intimate relationships. Sexual script flexibility (SSF) refers to the ability to adapt one's sexual scripts in response to sexual problems and may have implications for sexual adjustment. We studied SSF and its links to sexual self-efficacy and sexual satisfaction in BC survivor couples.</p><p><strong>Methods: </strong>One hundred-twenty female post-treatment BC survivors reporting sexual concerns and their spouses (98% male) participating in a couples' sexual health intervention trial completed baseline surveys assessing SSF, sexual self-efficacy, and sexual satisfaction. Analyses included paired t-tests comparing survivors and spouses on SSF, ANOVA's to assess effects of couple-level SSF on sexual self-efficacy and satisfaction, and Actor-Partner Interdependence (APIM) models using multilevel modeling with generalized least squares analysis to assess effects of survivors' and spouses' SSF on their own and their spouses' sexual self-efficacy and satisfaction.</p><p><strong>Results: </strong>Survivors reported lower SSF and sexual self-efficacy than spouses (p's ≤ 0.001). Couples where both members reported above median SSF (23% of couples) were distinguished by greater sexual self-efficacy and sexual satisfaction. APIM results indicated that (1) the greater survivors' and spouses' own SSF, the greater their own sexual self-efficacy (p < 0.01); (2) the greater survivors' SSF, the greater their own sexual satisfaction (p < 0.001); and (3) the greater survivors' SSF, the greater their partners' sexual satisfaction (p < 0.05).</p><p><strong>Conclusions: </strong>Greater sexual script flexibility may benefit BC survivor couples coping with sexual concerns. Future studies should examine whether intervention-related changes in SSF lead to better sexual outcomes, with survivors' flexibility an especially promising target.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 4","pages":"e70147"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12011320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-Sectional Analysis of Psychosocial Mediators Between Discrimination and Health-Related Quality of Life Among Sexual and Gender Minority Cancer Survivors.","authors":"Oscar Y Franco-Rocha, Christopher W Wheldon, Carolyn S Phillips, Mansi Patel, Tiffany A Whittaker, Shelli R Kesler, Ashley M Henneghan","doi":"10.1002/pon.70154","DOIUrl":"https://doi.org/10.1002/pon.70154","url":null,"abstract":"<p><strong>Background: </strong>Acts of discrimination detrimentally impact the quality of life of sexual and gender minority (SGM) cancer survivors. However, it is unclear how demographic and psychosocial factors shape the impact of discrimination on health.</p><p><strong>Aims: </strong>To evaluate the intermediating role of everyday discrimination on physical and mental health-related quality of life (HRQOL), and how such relationships vary based on the demographic and psychosocial factors of SGM survivors.</p><p><strong>Methods: </strong>Secondary analysis with 381 SGM cancer survivors participating in the All of Us (AoU) research program. Valid and reliable measures to assess depression, anxiety, stress, social support, and loneliness were used to test whether these psychosocial variables mediated the relationship between discrimination and HRQOL. The hypothesized model was tested using structural equation modeling in the AoU workbench's RStudio platform.</p><p><strong>Results: </strong>Discrimination affected physical (β = -0.141, p < 0.001) and mental (β = -0.115, p < 0.001) HRQOL through loneliness and psychological distress. The relationship between racial/ethnic minority status and physical (β = -0.045, p = 0.007) and mental (β = -0.036, p = 0.008) HRQOL was directly mediated by discrimination via psychological distress, and indirectly through loneliness and psychological distress (β physical HRQOL = -0.025, p = 0.010; β mental HRQOL = -0.020, p = 0.010).</p><p><strong>Conclusions: </strong>Loneliness and psychological distress mediate the relationship between discrimination and HRQOL. The impact of discrimination on HRQOL was particularly higher for SGM survivors that were also part of a racial or ethnic minority group. Addressing psychosocial mediators through tailored support programs could mitigate the harmful effects of discrimination, thereby improving HRQOL for SGM cancer survivors.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 4","pages":"e70154"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Reporting Completeness of Patient-Reported Outcome in Randomized Controlled Trials of Non-Small Cell Lung Cancer Could Be Improved: A Systematic Review.","authors":"Wenbo He, Fangyuan Jing, Yinyan Gao, Hang Yi, Meixuan Li, Jiuhong You, Yanjiao Shen, Yi Wu, Pan Kang, Zhiruo Yu, Xinyi Wang, Yunmei Luo, Zhengchi Li, Liang Du","doi":"10.1002/pon.70152","DOIUrl":"https://doi.org/10.1002/pon.70152","url":null,"abstract":"<p><strong>Background: </strong>Non-small cell lung cancer (NSCLC) remains a highly symptomatic with a rapidly increasing incidence. The treatment options are for most patients limited to adjuvant immunotherapy and best supportive care. Therefore, patient-reported outcomes (PROs) are increasingly becoming an essential component in evaluating healthcare quality from the patient's perspective.</p><p><strong>Purpose: </strong>We aimed to assess differences in the use of PROs measurement tools and their reporting quality in NSCLC randomized controlled trials (RCTs).</p><p><strong>Methods: </strong>We searched for reports of PROs in NSCLC RCT studies in PubMed, Embase, Web of Science, and Scopus before June 6, 2024. The quality of PRO reporting was assessed using criteria recommended by the International Society for Quality-of-Life Research. Multivariate linear regression was performed to examine the relationship between report quality and influencing factors.</p><p><strong>Results: </strong>A total of 252 RCTs were included in the analysis, with 23% of these studies reporting PROs as primary endpoints. Overall, studies with PROs as primary endpoints demonstrated higher adherence to the reporting checklist (76%). The results of multivariate linear regression indicated a significant improvement in PRO reporting quality over time (β = 5.35, 95% CI [1.05, 9.64], p < 0.05). However, substantial shortcomings were identified in PRO reporting, including incomplete reporting of missing data and a lack of details on PRO data management modes (e.g., telephone, computer, etc.).</p><p><strong>Conclusion: </strong>The deficiencies observed in PRO reporting underscore the need for improved design and implementation of PRO endpoints in future NSCLC trials. Enhancing the quality of PRO reporting could improve the relevance and applicability of research findings to clinical practice.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 4","pages":"e70152"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}