Natasha A Roberts, Ian D Davis, David Wyld, Jeffrey Goh, Maxwell Thompson, Craig Gedye, Haryana M Dhillon
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引用次数: 0
Abstract
Background: Clinical trials are fundamental to improving cancer treatment and clinical outcomes. Whilst clinical trials offer treatment options to affected individuals, less is known about how to best support those who participate.
Aim: To explore the experiences of participants in urogenital and prostate cancer clinical trials to identify opportunities to improve care for this cohort of patients.
Methods: This qualitative study was conducted in Australian hospitals. Participants were included if they had consented to participate in an Australian collaborative investigator led clinical trial for prostate or other urogenital cancer. Semi-structured interviews with participants were completed by telephone. Using verbatim transcriptions, their experiences relative to key stages of a clinical trial were analysed using a Framework Method. Findings were interpreted to develop key recommendations for use by investigators developing a clinical trial.
Results: 22 people consented and participated in interviews. They came from rural, regional, and metropolitan areas across Australia. Participants were being treated for advanced uro-genital and prostate cancers. Across interviews, participants spoke about their supportive care needs and how they valued their relationships with the multi-disciplinary research team and the clinical oncology and urology teams. There was variation in participant needs according to the stage of the clinical trial. Despite times of uncertainty, it was reported clinical trial participation was meaningful. Receiving information about overall findings of the clinical trial was important to participants allowing them to understand the impact of their contribution.
Conclusion: Understanding the experiences of clinical trial participants can improve the design of trial protocol processes and procedures. Participants want to stay connected with their clinical trial.
期刊介绍：
Psycho-Oncology is concerned with the psychological, social, behavioral, and ethical aspects of cancer. This subspeciality addresses the two major psychological dimensions of cancer: the psychological responses of patients to cancer at all stages of the disease, and that of their families and caretakers; and the psychological, behavioral and social factors that may influence the disease process. Psycho-oncology is an area of multi-disciplinary interest and has boundaries with the major specialities in oncology: the clinical disciplines (surgery, medicine, pediatrics, radiotherapy), epidemiology, immunology, endocrinology, biology, pathology, bioethics, palliative care, rehabilitation medicine, clinical trials research and decision making, as well as psychiatry and psychology.
This international journal is published twelve times a year and will consider contributions to research of clinical and theoretical interest. Topics covered are wide-ranging and relate to the psychosocial aspects of cancer and AIDS-related tumors, including: epidemiology, quality of life, palliative and supportive care, psychiatry, psychology, sociology, social work, nursing and educational issues.
Special reviews are offered from time to time. There is a section reviewing recently published books. A society news section is available for the dissemination of information relating to meetings, conferences and other society-related topics. Summary proceedings of important national and international symposia falling within the aims of the journal are presented.
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