Psycho‐Oncology最新文献

{"title":"Family Resilience in Adolescent and Young Adult Patients With Hematological Malignancies: A Qualitative Study of Patients and Family Caregivers.","authors":"Yiwen Zhang, Li Wang, Rui Cao, Lu Chen, Hongyan Yuan, Ruiye Li, Xiuping Jiang, Yanmei Cheng, Huijing Zou, Bing Xiang Yang, Qian Liu","doi":"10.1002/pon.70224","DOIUrl":"https://doi.org/10.1002/pon.70224","url":null,"abstract":"<p><strong>Objective: </strong>Family resilience plays a vital role in coping with cancer. However, little research has explored how adolescents and young adults (AYAs) with hematological malignancies and their families adapt to cancer, particularly during this critical developmental stage.</p><p><strong>Aims: </strong>This study aims to explore how AYAs with hematological malignancies and their families experience the dynamic process of family resilience.</p><p><strong>Methods: </strong>Using a descriptive phenomenological approach, semi-structured interviews were conducted with 40 participants from 26 families, including 19 AYAs with hematological malignancies and 21 family caregivers. Data were collected between April 2023 and March 2025 at two general hospitals in central China. Interviews were analyzed using Colaizzi's method.</p><p><strong>Results: </strong>Four themes and 11 subthemes emerged. Theme 1: challenges faced by families: (a) multiple challenges for patients, (b) intense family caregiver burden, and (c) shared fear of relapse and uncertainty. Theme 2: internal adaptation within families: (a) flexible role and responsibility adjustment, (b) fostering shared decision-making and autonomy through communication, and (c) emotional suppression and coping strategies. Theme 3: external social support and resources: (a) received social support, and (b) limitations in the social support system. Theme 4: self-transcendence and growth: (a) personal growth, (b) gratitude toward family and society, and (c) maintaining hope and adjusting plans.</p><p><strong>Conclusions: </strong>This study reveals that family resilience among AYAs with hematological malignancies is a dynamic and cyclical process shaped by continuous adaptation to evolving challenges. While family resilience supports personal growth, families remain under ongoing stress. These findings highlight the need for culturally sensitive and developmentally tailored interventions to better support both patients and caregivers throughout the illness trajectory.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70224"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144619931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Communication Skills Training to Improve Confidence and Skills in Pediatric Cancer Truth-Telling of Registered Nurses: A Quasi-Experimental Study.","authors":"Shih-Ying Chen, Shih-Hsiang Chen, Meng-Xian Zhou, Chih-Cheng Hsiao, Chung-Chih Lin, Ji-Tseng Fang, Maiko Fujimori, Woung-Ru Tang","doi":"10.1002/pon.70215","DOIUrl":"https://doi.org/10.1002/pon.70215","url":null,"abstract":"<p><strong>Aims: </strong>Evaluate the effectiveness of combining an online pediatric communication skill training (PedCST) with an interactive e-picture book application by measuring outcomes for registered nurses (RNs), children with leukemia, and their parents.</p><p><strong>Methods: </strong>This quasi-experimental study implemented a PedCST designed for RNs followed by an interactive e-picture book application for children with leukemia and their parents. Outcome variables included RNs' communication confidence and skills; children's quality of life (QOL) and symptom distress; and parents' QOL, satisfaction with medical communication, and emotional distress. Multiple linear regression was used for data analysis.</p><p><strong>Results: </strong>Forty-three pediatric RNs and 29 pairs of children with leukemia and their parents were recruited. The PedCST effectively enhanced the RNs' confidence (p < 0.001, f = 0.68) and communication skills (p < 0.001, f = 0.26) when interacting with children with leukemia and their parents. The combined intervention showed a large effect on enhancing children's QOL (76.4 vs. 87.1, p < 0.01, f = 0.66) and relieving several distress symptoms (depression, anxiety, and appetite), but it had a limited impact on improving parents' QOL (54.1 vs. 48.0, p = 0.202), satisfaction with medical communication (4.4 vs. 4.5, p = 0.159), or emotional distress (3.3 vs. 2.6, p = 0.209).</p><p><strong>Conclusions: </strong>The PedCST enhanced RNs' confidence and communication skills. Additionally, the combined intervention effectively improved children's QOL and emotional well-being. However, its impact on parents' QOL, communication satisfaction, and emotional distress could not be confirmed with our quasi-experimental design. These findings demonstrated the potential effectiveness of the innovative intervention; however, further research with a control group is necessary to accurately confirm its effectiveness.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70215"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144542050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial Interventions to Relieve Traumatic Stress Symptoms in Family Caregivers of Children With Cancer: A Scoping Review.","authors":"Stephanie M Nanos, Argin Malakian, Laura Foran, Elizaveta Klekovkina, Kyle P Fitzgibbon, Ally Yu, Angela Mathews, Gary Rodin, Lindsay A Jibb","doi":"10.1002/pon.70230","DOIUrl":"10.1002/pon.70230","url":null,"abstract":"<p><strong>Background: </strong>Traumatic stress symptoms are common, severe, and persistent in family caregivers of children with cancer, but the benefits of therapeutic interventions to relieve them are not well established.</p><p><strong>Aim: </strong>To review, describe, and appraise the available research on psychosocial interventions aimed at alleviating traumatic stress symptoms in family caregivers of children with cancer.</p><p><strong>Methods: </strong>Systematic searches of APA PsycInfo, CINAHL, MEDLINE, and Embase were conducted to identify randomized controlled trials (RCTs) and nonrandomized studies of psychosocial interventions (NRSIs) for families affected by pediatric cancer in which traumatic stress symptoms were reported as a primary or secondary outcome. Results were screened by independent reviewers in duplicate. 18 articles were included. All were evaluated for risk of bias and data on study design, intervention format, delivery, and impact, and were abstracted for narrative synthesis.</p><p><strong>Results: </strong>Study samples (8-430 participants) were primarily comprised of mothers of children with acute leukemia. Most interventions (1 day-15 weeks) involved an interventionist (n = 17; 94%) and used cognitive-behavioral techniques (n = 14; 78%). Eight RCTs (n = 10; 80%) and seven NRSIs (n = 8; 87.5%) found a significant reduction in traumatic stress symptoms following intervention delivery, with small to large effect sizes (Cohen's d = 0.28-1.30). However, only three RCTs confirmed having adequate power to comment on effectiveness. Risk of bias ranged from low to moderate.</p><p><strong>Conclusions: </strong>The prevalence and problematic nature of traumatic stress symptoms in this population is well documented in the observational literature. However, the evidence remains unclear as to the effectiveness of psychosocial interventions to alleviate them due to methodological limitations in current interventional research. High quality RCTs that include a diverse group of family caregivers are needed to demonstrate their effectiveness and to inform clinical care practices aimed at improving family wellbeing.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70230"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociocultural Factors Influencing Late Presentation for Health Care Among Cervical Cancer Patients: A Qualitative Exploratory Study.","authors":"Cynthia Mwachande, Dorothy Adong Olet, Stanley Wilson Acuda, Mwandida Matilda Nkhoma, Germanus Natuhwera","doi":"10.1002/pon.70229","DOIUrl":"https://doi.org/10.1002/pon.70229","url":null,"abstract":"<p><strong>Introduction: </strong>Malawi has the highest cervical cancer mortality rates in the world. Late presentation for care associated with late diagnosis and poor survival rates remain a huge issue. Research into social and cultural factors and how these influence women's access to early healthcare in Malawi is still scanty.</p><p><strong>Objective: </strong>This study aimed to explore sociocultural factors that influence late presentation for healthcare among cervical cancer patients at Zomba Central Hospital, Malawi.</p><p><strong>Methods: </strong>This qualitative exploratory descriptive study recruited purposively selected women with advanced cancer of the cervix attending Zomba Central Hospital in Southeastern Malawi. Data were collected through one-on-one audio-taped interviews using a pilot-tested semi-structured interview guide. Thematic data analysis was used. Data saturation was reached at the 21^st interview.</p><p><strong>Results: </strong>21 patients living with cervical cancer participated. Two broad domains and six main themes; three themes under each domain emerged: Domain 1: Sociocultural barriers (knowledge gap about cervical cancer, influence of culture and social networks, poverty and financial cost as a barrier) and Domain 2: Healthcare system-related barriers (access barriers related to limited health (cancer) care services, delays in the healthcare and referral system, human resource and knowledge gaps among health professionals).</p><p><strong>Conclusion: </strong>All the participants in this study narrated that they presented late when the cancer was already advanced with no possibility of cure. Ignorance about cervical cancer was common to all the participants in this study and appeared to be a wider sociocultural issue. There is an urgent need for multistakeholder and multicultural involvement and strengthening mass education of the community about cancer to improve awareness, destigmatize cancer, and dispel harmful cultural beliefs and practices regarding causes and treatment of cervical cancer. Training of health professionals at all levels about early detection and effective referral pathways is also urgent.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70229"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Parental Distress in Children's Health-Related Quality of Life in Pediatric Acute Lymphoblastic Leukemia.","authors":"Ana Ferraz, Susana Faria, Mónica Jerónimo, M Graça Pereira","doi":"10.1002/pon.70207","DOIUrl":"https://doi.org/10.1002/pon.70207","url":null,"abstract":"<p><strong>Objective: </strong>The diagnosis of childhood acute lymphoblastic leukemia (ALL) and the subsequent treatment-related challenges impact the children's health-related quality of life (HRQoL) and parental distress (psychological morbidity and traumatic stress symptoms). This study examined the relationship between parental distress and children's HRQoL, focusing on preschool-aged children and toddlers. The aims were: to assess changes in children's HRQoL over time, compare HRQoL between children with ALL and healthy children, and evaluate the longitudinal association between parental distress and children's HRQoL.</p><p><strong>Methods: </strong>The sample consisted of 46 parents of children with ALL, 58 parents of healthy children, and their children. Assessments were conducted in the first week of three treatment phases, (T0-Consolidation; T1-Intensification; T2-Maintenance). Linear mixed models and Mann-Whitney U tests were performed. Results revealed significant improvements in children's HRQoL over time, although lower than the healthy group. Parental psychological morbidity was associated with children's HRQoL at T1 but not at T2. Traumatic stress symptoms showed no association with children's HRQoL.</p><p><strong>Conclusion: </strong>These findings underscore the importance of targeting parental psychological morbidity (anxiety and depression symptoms) during more intensive treatment phases. Incorporating family-centered care strategies that address parents' psychological morbidity can promote better outcomes for both children and parents, supporting adaptation during this challenging period.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70207"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oncologist and General Practitioner Perspectives of Shared Care for Colorectal Cancer Survivors: A Qualitative Study.","authors":"Karolina Lisy, Matthew Tieu, Claire Gore, Penelope Schofield, Raymond J Chan, Jon Emery, Andrew Martin, Richard De Abreu Lourenco, Michael Jefford","doi":"10.1002/pon.70223","DOIUrl":"10.1002/pon.70223","url":null,"abstract":"<p><strong>Background: </strong>There is a growing body of evidence to support shared survivorship care. The shared care of colorectal cancer survivors (SCORE) randomised controlled trial (RCT) demonstrated that shared care is an appropriate and cost-effective model. Understanding the perspectives of oncologists and general practitioners (GPs) who participated in SCORE will provide crucial insights to support wider implementation of shared care and adoption into clinical practice.</p><p><strong>Aims: </strong>To explore the experiences of oncologists and GPs who provided shared survivorship care for colorectal cancer survivors within the SCORE RCT, focussing on perceptions of acceptability and appropriateness of shared care, and facilitators and barriers to implementation.</p><p><strong>Methods: </strong>This qualitative descriptive study utilised semi-structured interviews for data collection. Interviews were recorded and transcribed, and data analysed by hybrid deductive/inductive thematic analysis.</p><p><strong>Results: </strong>Interviews from 20 HCPs (13 GPs and 7 oncologists) were analysed. Seven themes were developed describing overall acceptance of the shared care model, the importance and challenges regarding bilateral communication between providers, mixed views on the need for GP training, and patients suitable for shared care. The need to support GPs with a direct hospital-based contact person, as well as clear guidance on their role, was emphasised, as was the need for care coordination and logistical support.</p><p><strong>Conclusions: </strong>Our study offers novel findings regarding shared care from the perspective of participants who have direct experience with delivering the model. While shared care was broadly supported by both GPs and specialists, successful implementation requires agreed-upon bilateral communication, clear guidance for GPs, and coordination support.</p><p><strong>Clinical trial registration: </strong>The Shared Care for Colorectal Cancer (SCORE) Trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12617000004369p. Registered on 3 January 2017; protocol version 4 approved 24 February 2017.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70223"},"PeriodicalIF":3.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144619932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of a Predictive Model for Anticipatory Grief in Family Caregivers of Cancer Patients: Based on LASSO-Logistic Regression Model.","authors":"Di Sun, Tingting Huang, Jiaojiao Li, Meishuo Liu, Xu Zhang, Mengyao Cui","doi":"10.1002/pon.70236","DOIUrl":"10.1002/pon.70236","url":null,"abstract":"<p><strong>Background: </strong>Anticipatory grief is a significant emotional challenge for family caregivers of cancer patients, yet its early identification remains limited by subjective assessments and a lack of predictive tools. This study aimed to develop and validate a predictive model for anticipatory grief among family caregivers of cancer patients in China.</p><p><strong>Methods: </strong>A multicenter cross-sectional study was conducted from February to October 2023, involving 642 family caregivers of lung and breast cancer patients from two tertiary hospitals in Liaoning Province, China. Latent Profile Analysis (LPA) classified caregivers into anticipatory grief risk categories based on the Anticipatory Grief Scale. LASSO-logistic regression was used to identify predictors and construct a predictive model, which was validated using discrimination (AUC), calibration (Hosmer-Lemeshow test), and clinical utility (Decision Curve Analysis). A web-based nomogram was developed for practical application.</p><p><strong>Results: </strong>The mean anticipatory grief score was 72.44 ± 18.49, with LPA identifying three profiles: low (54.52%), moderate (30.53%), and high (14.95%) anticipatory grief. Seven predictors were identified: caregiver education level, monthly income, physical condition, caregiving duration, and patient cancer type, employment status, and time since diagnosis. The model showed good discrimination (AUC: 0.769 training, 0.671 validation), calibration (P = 0.095 training, P = 0.801 validation), and clinical utility (net benefit at 34%-62% threshold). The web-based tool is accessible at https://nomogrameofag.shinyapps.io/dynnomapp/.</p><p><strong>Conclusions: </strong>This study developed a predictive model for anticipatory grief, identifying key risk factors and providing a practical tool for healthcare providers to identify high-risk caregivers. The findings support targeted interventions to enhance caregiver well-being and patient care quality, though future research should expand cancer types and incorporate qualitative insights for broader applicability.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70236"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"These Drugs Are Going to Save Our Lives\" A Mixed Methods Study on the Role of Medication Perceptions in Adherence to Oral Anticancer Agents Among Patients With Gastrointestinal Tract Cancer.","authors":"Yongfeng Chen, Marques Shek Nam Ng, Bei Dong, Carmen Wing Han Chan","doi":"10.1002/pon.70213","DOIUrl":"10.1002/pon.70213","url":null,"abstract":"<p><strong>Objective: </strong>Patients with gastrointestinal tract cancer reported suboptimal adherence to oral anticancer agents (OAAs), reducing the therapeutic benefit. According to the Common-Sense Model of Self-Regulation, patients' medication perceptions decide adherence. However, how perceptions of OAAs influence adherence remains unknown among this population. This study explored this relationship.</p><p><strong>Methods: </strong>A convergent mixed methods study was conducted. In the quantitative part, medication perceptions were evaluated among 253 participants using the Beliefs about Medicines Questionnaire, Perceived Sensitivity to Medicine, and Self-efficacy for Appropriate Medication Use Scale. Adherence was measured by the Morisky 4-item Medication Adherence Scale. In the qualitative part, 37 participants from the quantitative cohort were interviewed concurrently. Perceptions of OAAs were identified using content analysis. Findings were integrated using side-by-side comparisons and joint displays.</p><p><strong>Results: </strong>Quantitative data showed that 58.89% of patients were considered adherent. Adherent patients exhibited lower harm beliefs, less sensitivity to medicine, and higher medication self-efficacy. Qualitative data identified four categories of perceptions: emphasizing the effectiveness of OAAs despite the hazardous nature, experiencing negative emotions in relation to taking OAAs, taking responsibility for OAAs routine management, and encountering multiple barriers to taking OAAs. The qualitative findings supplemented the quantitative results regarding the associations between harm beliefs, perceived sensitivity to medicine, medication self-efficacy, and adherence; however, they revealed a discordance in the associations between necessity beliefs, concern beliefs, and adherence.</p><p><strong>Conclusions: </strong>Strategies targeting medication perceptions were suggested to promote adherence to OAAs, particularly those aimed at modifying negative medication beliefs and emotions, enhancing medication self-efficacy, and improving self-management abilities.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70213"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An HRQOL Proof-Of-Concept Analysis of the eHealth TOGETHER Intervention for Adolescent and Young Adult Cancer Survivors: A Brief Report.","authors":"Rina S Fox, Terry A Badger, Samantha Moya, Lisa M Gudenkauf, Marjorie A Nelson, Riley M O'Neill, Jacqueline J Leete, Sydney E Friedman, Emmanuel Katsanis, David E Victorson, Stacy D Sanford, Frank J Penedo, Michael H Antoni, Laura B Oswald","doi":"10.1002/pon.70234","DOIUrl":"10.1002/pon.70234","url":null,"abstract":"<p><strong>Background: </strong>Adolescent and young adult (AYA) cancer survivors ages 18-39 report elevated stress and poor health-related quality of life (HRQOL), yet few evidence-based stress management interventions exist that meet their specific needs. Our team designed TOGETHER, a 10-week eHealth group-delivered behavioral intervention designed to improve HRQOL via stress management skills training. To date, TOGETHER has been delivered to seven groups of AYAs, and its feasibility and acceptability have been well established.</p><p><strong>Aims: </strong>This proof-of-concept analysis explored TOGETHER's impact on patient-reported outcomes among AYAs.</p><p><strong>Methods: </strong>Participants were English-speaking AYAs aged 18-39 who were diagnosed with cancer while aged 15-39 and had completed curative treatment within the past five years. Patient-reported outcomes were assessed at baseline and post-intervention and included HRQOL, stress management skills self-efficacy, coping strategies, and depression and anxiety symptoms. Pre-to-post-intervention changes were assessed with paired-samples t-tests among those with complete data (n = 39) and using a series of imputation strategies. The proportion of participants achieving clinically meaningful change was computed when possible.</p><p><strong>Results: </strong>Participants (N = 51) had an average age of 29 years and were predominantly female (78%), White (69%), and non-Hispanic (80%). HRQOL significantly improved from pre-to post-intervention with small-to-moderate effect sizes (gs ranged from 0.32-0.60), and more than half of participants (51%-59%) demonstrated clinically meaningful improvement. Statistically significant improvements were found for stress management skills self-efficacy, coping, and depression symptoms, but not anxiety symptoms.</p><p><strong>Conclusions: </strong>Results provide proof-of-concept evidence that TOGETHER can meaningfully improve patient-reported outcomes among AYA survivors, supporting continued evaluation of the intervention.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov; NCT05048316, NCT05054569, NCT05597228, NCT05952492.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70234"},"PeriodicalIF":3.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Psychosocial Factors and Decision Making Regarding Primary Treatment in Older Women With Early-Stage Breast Cancer.","authors":"G Hindler, I Alabaster, R Zahit, A Jahan, D Giza, H M Holmes, H Blake, K-L Cheung, R M Parks","doi":"10.1002/pon.70240","DOIUrl":"10.1002/pon.70240","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer is increasingly prevalent among older adults, who are likely to have numerous comorbidities and unique psychosocial challenges.</p><p><strong>Aims: </strong>The aim of this study was to measure the prevalence of psychosocial factors in a cohort of older women diagnosed with early-stage operable breast cancer and the influence these factors may have on treatment decisions.</p><p><strong>Methods: </strong>As part of a prospective study in three UK centres, 199 patients with a new diagnosis of early-stage operable primary breast cancer, aged ≥ 70 years (mean 77, range 68-93) were recruited. A cancer-specific Comprehensive Geriatric Assessment (CGA) was conducted within 6 weeks of diagnosis. Association between treatment decision and psychosocial aspects (as measured by the 'psychosocial support', 'social activity' and 'social support' domains) of the CGA was determined. Treatment decision was not guided by this study and was determined usual conventional methods as per the breast multi-disciplinary team.</p><p><strong>Results: </strong>Scores for 'psychosocial support' averaged 82.1/102, 'social activity' averaged 13.5/24, and 'social support' averaged 43.3/72; with a higher score indicating a more positive outcome. There was no association between total scores in these domains and the type of treatment received. A lower score in three individual questions was associated with a higher likelihood of non-surgical treatment.</p><p><strong>Conclusions: </strong>While no direct link emerged between overall psychosocial scores and treatment decisions using CGA, specific sub-questions displayed associations with non-surgical treatment. This study is the only one of its kind to our knowledge. This may have implications for the design of a pre-CGA screening tool.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70240"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12286772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}